JP2023524206A5 - - Google Patents
Info
- Publication number
- JP2023524206A5 JP2023524206A5 JP2022564519A JP2022564519A JP2023524206A5 JP 2023524206 A5 JP2023524206 A5 JP 2023524206A5 JP 2022564519 A JP2022564519 A JP 2022564519A JP 2022564519 A JP2022564519 A JP 2022564519A JP 2023524206 A5 JP2023524206 A5 JP 2023524206A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- pharmaceutically acceptable
- acceptable salt
- compound according
- tetrahydroisoquinoline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2005863.2 | 2020-04-22 | ||
| GBGB2005863.2A GB202005863D0 (en) | 2020-04-22 | 2020-04-22 | Therapeutic compounds |
| PCT/GB2021/050973 WO2021214470A1 (en) | 2020-04-22 | 2021-04-22 | Tetrahydroisoquinoline compounds as nrf2 activators |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023524206A JP2023524206A (ja) | 2023-06-09 |
| JP2023524206A5 true JP2023524206A5 (https=) | 2024-05-01 |
| JP7679400B2 JP7679400B2 (ja) | 2025-05-19 |
Family
ID=70860156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022564519A Active JP7679400B2 (ja) | 2020-04-22 | 2021-04-22 | Ｎｒｆ２活性化剤としてのテトラヒドロイソキノリン化合物 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20230167084A1 (https=) |
| EP (1) | EP4139294B1 (https=) |
| JP (1) | JP7679400B2 (https=) |
| KR (1) | KR20230004720A (https=) |
| CN (1) | CN115667243B (https=) |
| AR (1) | AR121912A1 (https=) |
| AU (1) | AU2021259366A1 (https=) |
| BR (1) | BR112022021244A2 (https=) |
| CA (1) | CA3174361A1 (https=) |
| ES (1) | ES3032247T3 (https=) |
| GB (1) | GB202005863D0 (https=) |
| IL (1) | IL297434A (https=) |
| MX (1) | MX2022013398A (https=) |
| PH (1) | PH12022552775A1 (https=) |
| WO (1) | WO2021214470A1 (https=) |
| ZA (1) | ZA202211465B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2021004566A (es) | 2018-10-22 | 2021-06-08 | C4X Discovery Ltd | Compuestos terapeuticos. |
| PE20241779A1 (es) * | 2022-01-07 | 2024-09-03 | Chugai Pharmaceutical Co Ltd | Compuesto heterociclico que contiene nitrogeno que tiene un efecto de activacion del nrf2 |
| WO2025237912A1 (en) | 2024-05-13 | 2025-11-20 | Astrazeneca Ab | Keap1 inhibitors for use in the treatment of bronchiectasis |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003041641A2 (en) * | 2001-11-09 | 2003-05-22 | Bristol-Myers Squibb Company | Tetrahydroisoquinoline analogs as modulators of chemokine receptor activity |
| US20140256767A1 (en) * | 2011-10-31 | 2014-09-11 | The Broad Institute, Inc. | Direct inhibitors of keap1-nrf2 interaction as antioxidant inflammation modulators |
| CA2988373A1 (en) * | 2015-06-15 | 2016-12-22 | Glaxosmithkline Intellectual Property Development Limited | Nrf2 regulators |
| JP2020097526A (ja) * | 2017-03-28 | 2020-06-25 | 武田薬品工業株式会社 | 複素環化合物 |
| MX2021004566A (es) * | 2018-10-22 | 2021-06-08 | C4X Discovery Ltd | Compuestos terapeuticos. |
-
2020
- 2020-04-22 GB GBGB2005863.2A patent/GB202005863D0/en not_active Ceased
-
2021
- 2021-04-22 US US17/920,226 patent/US20230167084A1/en active Pending
- 2021-04-22 CN CN202180031435.0A patent/CN115667243B/zh active Active
- 2021-04-22 AU AU2021259366A patent/AU2021259366A1/en active Pending
- 2021-04-22 CA CA3174361A patent/CA3174361A1/en active Pending
- 2021-04-22 EP EP21723350.1A patent/EP4139294B1/en active Active
- 2021-04-22 KR KR1020227040550A patent/KR20230004720A/ko active Pending
- 2021-04-22 WO PCT/GB2021/050973 patent/WO2021214470A1/en not_active Ceased
- 2021-04-22 IL IL297434A patent/IL297434A/en unknown
- 2021-04-22 AR ARP210101080A patent/AR121912A1/es unknown
- 2021-04-22 PH PH1/2022/552775A patent/PH12022552775A1/en unknown
- 2021-04-22 BR BR112022021244A patent/BR112022021244A2/pt unknown
- 2021-04-22 MX MX2022013398A patent/MX2022013398A/es unknown
- 2021-04-22 ES ES21723350T patent/ES3032247T3/es active Active
- 2021-04-22 JP JP2022564519A patent/JP7679400B2/ja active Active
-
2022
- 2022-10-19 ZA ZA2022/11465A patent/ZA202211465B/en unknown
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