JP2023524133A5 - - Google Patents

Info

Publication number
JP2023524133A5
JP2023524133A5 JP2022567286A JP2022567286A JP2023524133A5 JP 2023524133 A5 JP2023524133 A5 JP 2023524133A5 JP 2022567286 A JP2022567286 A JP 2022567286A JP 2022567286 A JP2022567286 A JP 2022567286A JP 2023524133 A5 JP2023524133 A5 JP 2023524133A5
Authority
JP
Japan
Prior art keywords
ethyl
oxo
trifluoromethoxy
phenyl
triazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022567286A
Other languages
English (en)
Japanese (ja)
Other versions
JP7697974B2 (ja
JP2023524133A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2021/000304 external-priority patent/WO2021224680A1/en
Publication of JP2023524133A publication Critical patent/JP2023524133A/ja
Publication of JP2023524133A5 publication Critical patent/JP2023524133A5/ja
Application granted granted Critical
Publication of JP7697974B2 publication Critical patent/JP7697974B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022567286A 2020-05-08 2021-05-06 Ｇｐｒ１３９アゴニストの置換ベンゾトリアジノン代謝物 Active JP7697974B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063021895P 2020-05-08 2020-05-08
US63/021,895 2020-05-08
PCT/IB2021/000304 WO2021224680A1 (en) 2020-05-08 2021-05-06 Substituted benzotriazinone metabolites of a gpr139 agonist

Publications (3)

Publication Number Publication Date
JP2023524133A JP2023524133A (ja) 2023-06-08
JP2023524133A5 true JP2023524133A5 (https=) 2024-04-30
JP7697974B2 JP7697974B2 (ja) 2025-06-24

Family

ID=76624075

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022567286A Active JP7697974B2 (ja) 2020-05-08 2021-05-06 Ｇｐｒ１３９アゴニストの置換ベンゾトリアジノン代謝物

Country Status (5)

Country Link
US (1) US12559465B2 (https=)
EP (1) EP4146635A1 (https=)
JP (1) JP7697974B2 (https=)
CA (1) CA3177117A1 (https=)
WO (1) WO2021224680A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CR20220160A (es) 2019-09-16 2022-06-16 Takeda Pharmaceuticals Co Derivados de piridazin-3(2h)-ona fusionados con azol
WO2021224680A1 (en) 2020-05-08 2021-11-11 Takeda Pharmaceutical Company Limited Substituted benzotriazinone metabolites of a gpr139 agonist
CN116693545A (zh) * 2022-03-01 2023-09-05 上海科技大学 噻吩并含氮杂环类化合物、含其的药物组合物、其制备方法及其应用
CN116693536A (zh) * 2022-03-01 2023-09-05 上海科技大学 吡咯并三嗪酮类化合物、含其的药物组合物、其制备方法及其应用
CN121159462A (zh) * 2025-11-19 2025-12-19 杭州市第七人民医院(杭州市心理危机研究与干预中心) 喹唑啉酮类化合物及其在制备神经系统疾病药物中的应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3794726A (en) 1972-08-21 1974-02-26 Uniroyal Inc Inhibiting aggressive behavior with 1,2,3-benzotriazin-(3h)-one
EP0315390B1 (en) 1987-11-04 1994-07-20 Beecham Group Plc Novel 4-oxobenzotriazines and 4-oxoquinazolines
JP4079727B2 (ja) * 2002-09-06 2008-04-23 セントラル硝子株式会社 光学活性１−（フルオロ、トリフルオロメチルまたはトリフルオロメトキシ置換フェニル）アルキルアミンｎ−モノアルキル誘導体とその製造方法
CA2526506A1 (en) 2003-06-09 2004-12-16 Boehringer Ingelheim International Gmbh Inhibitors of papilloma virus
AU2004261283B2 (en) 2003-07-31 2008-05-01 Irm, Llc Bicyclic compounds and compositions as PDF inhibitors
FR2875805B1 (fr) 2004-09-27 2006-12-29 Genfit S A Composes derives de n-(benzyl) phenylacetamide substitues, preparation et utilisations
TW200736227A (en) 2005-12-23 2007-10-01 Astrazeneca Ab New compounds III
TWI433839B (zh) 2006-08-11 2014-04-11 Neomed Inst 新穎的苯并咪唑衍生物290
WO2009086303A2 (en) 2007-12-21 2009-07-09 University Of Rochester Method for altering the lifespan of eukaryotic organisms
WO2011138265A2 (en) 2010-05-03 2011-11-10 Evotec Ag Indole and indazole derivatives as orexin receptor antagonists
WO2014152917A2 (en) 2013-03-14 2014-09-25 Janssen Pharmaceutica Nv Physiological ligands for gpr139
JO3719B1 (ar) 2014-11-20 2021-01-31 Takeda Pharmaceuticals Co 4- أوكسو-4،3- داي هيدرو-3،2،1- بنزوترايازينات كمواد ضابطة لأجل gpr139
CR20220160A (es) 2019-09-16 2022-06-16 Takeda Pharmaceuticals Co Derivados de piridazin-3(2h)-ona fusionados con azol
WO2021224680A1 (en) 2020-05-08 2021-11-11 Takeda Pharmaceutical Company Limited Substituted benzotriazinone metabolites of a gpr139 agonist
US20230310441A1 (en) 2020-09-21 2023-10-05 Takeda Pharmaceutical Company Treatment for schizophrenia

Similar Documents

Publication Publication Date Title
JP2023524133A5 (https=)
JP2021534124A5 (https=)
JP2010508360A5 (https=)
JP7358342B2 (ja) 新規なグルタミンアンタゴニストおよびそれらの使用
JP2013535460A5 (https=)
CN105579035B (zh) 二巯基化物类粘液溶解剂
JP2024514010A5 (https=)
RU2005100836A (ru) Производные пептидов, содержащие тиазепиновую группу, для лечения гиперлипемических состояний
CN105001165A (zh) 取代的二氨基嘧啶其组合物，和用其治疗的方法
CN1169145A (zh) 新的法呢基转移酶抑制剂、其制法及其药物组合物
RU2009112719A (ru) Производные n-биарил(гетеро)арилсульфонамида, применимые в лечении заболеваний, опосредованных взаимодействием лимфоцитов
JP2010508361A5 (https=)
JP2022533913A5 (https=)
RU2008142834A (ru) Модуляция церамидкиназы
RU2013108702A (ru) Ингибиторы деметилазы lsd1 на основе арилциклопропиламина и их применение в медицине
JP2018528261A (ja) グルタミン類似体のプロドラッグ
RU2007124545A (ru) Производные [4-(гетероарил)пиперазин-1-ил]-(2,5-замещенный фенил)метанона в качестве ингибиторов переносчика глицина-1 (glyt-1) для лечения неврологических и психоневрологических заболеваний
EA200601287A1 (ru) Производные (3-оксо-3,4-дигидрохиноксалин-2-иламино) бензамида и родственные соединения в качестве ингибиторов гликогенфосфорилазы для лечения диабета и ожирения
US20250135005A1 (en) Processes for preparing functionalized cyclooctenes
JP2010533131A5 (https=)
RU2010145463A (ru) Производные замещенного 2-фенилпиридина
JP2024525693A5 (https=)
CN1104214A (zh) 新颖的2-硫代碳青霉烯
KR20170108088A (ko) 신규 모노티올 점액용해제
RU2008128875A (ru) Аминное соединение и его применение в медицинских целях