JP2024525693A5 - - Google Patents
Info
- Publication number
- JP2024525693A5 JP2024525693A5 JP2024501540A JP2024501540A JP2024525693A5 JP 2024525693 A5 JP2024525693 A5 JP 2024525693A5 JP 2024501540 A JP2024501540 A JP 2024501540A JP 2024501540 A JP2024501540 A JP 2024501540A JP 2024525693 A5 JP2024525693 A5 JP 2024525693A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- alkyl
- tautomer
- prodrug
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163222380P | 2021-07-15 | 2021-07-15 | |
| US63/222,380 | 2021-07-15 | ||
| PCT/US2022/037387 WO2023288109A1 (en) | 2021-07-15 | 2022-07-15 | N-heterocyclyl substituted 2-cyano-3-(naphthalen-2-yl)acrylamide derivatives as fluorophors for detection of amyloid and amyloid-like proteins for diagnosis of neurodegenerative disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024525693A JP2024525693A (ja) | 2024-07-12 |
| JP2024525693A5 true JP2024525693A5 (https=) | 2025-07-16 |
Family
ID=82943006
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024501540A Pending JP2024525693A (ja) | 2021-07-15 | 2022-07-15 | 神経変性障害の診断のためにアミロイドおよびアミロイド様タンパク質を検出するためのフルオロフォアとしてのｎ－ヘテロシクリル置換２－シアノ－３－（ナフタレン－２－イル）アクリルアミド誘導体 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20240325572A1 (https=) |
| EP (1) | EP4370510A1 (https=) |
| JP (1) | JP2024525693A (https=) |
| CN (1) | CN117916225A (https=) |
| AU (1) | AU2022310502A1 (https=) |
| CA (1) | CA3226490A1 (https=) |
| WO (1) | WO2023288109A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA52796A (fr) | 2018-05-31 | 2021-04-14 | Amydis Inc | Compositions et procédés de détection d'une lésion cérébrale traumatique |
| IL305647A (en) * | 2021-03-12 | 2023-11-01 | Amydis Inc | Methods for the detection of systemic amyloidosis by binding to misfolded protein or aggregates |
| WO2024155678A1 (en) * | 2023-01-18 | 2024-07-25 | Amydis, Inc. | Amyloid targeting agents |
| CN116178303B (zh) * | 2023-03-17 | 2024-04-02 | 许昌学院 | 一类含氮荧光染料、其合成方法及应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2015231239B2 (en) * | 2014-03-19 | 2018-11-29 | Amydis, Inc. | Amyloid targeting agents and methods of using the same |
| WO2016040891A2 (en) * | 2014-09-12 | 2016-03-17 | Amydis Diagnostics | In vitro compositions comprising human sample and amyloid targeting agent |
| MA52796A (fr) * | 2018-05-31 | 2021-04-14 | Amydis Inc | Compositions et procédés de détection d'une lésion cérébrale traumatique |
| AU2019372432B2 (en) | 2018-11-02 | 2025-05-29 | Amydis, Inc. | Phosphate compounds for detecting neurological disorders |
| AU2020348382A1 (en) * | 2019-09-18 | 2022-04-28 | Amydis, Inc. | Methods of detecting neurological disorders via binding to phosphorylated tau protein |
-
2022
- 2022-07-15 JP JP2024501540A patent/JP2024525693A/ja active Pending
- 2022-07-15 CA CA3226490A patent/CA3226490A1/en active Pending
- 2022-07-15 CN CN202280060212.1A patent/CN117916225A/zh active Pending
- 2022-07-15 US US18/579,251 patent/US20240325572A1/en active Pending
- 2022-07-15 AU AU2022310502A patent/AU2022310502A1/en active Pending
- 2022-07-15 WO PCT/US2022/037387 patent/WO2023288109A1/en not_active Ceased
- 2022-07-15 EP EP22757396.1A patent/EP4370510A1/en active Pending
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