JP2023523218A5 - - Google Patents

Info

Publication number
JP2023523218A5
JP2023523218A5 JP2022563971A JP2022563971A JP2023523218A5 JP 2023523218 A5 JP2023523218 A5 JP 2023523218A5 JP 2022563971 A JP2022563971 A JP 2022563971A JP 2022563971 A JP2022563971 A JP 2022563971A JP 2023523218 A5 JP2023523218 A5 JP 2023523218A5
Authority
JP
Japan
Prior art keywords
approximately
cancer
weeks
storage
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022563971A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023523218A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2021/053254 external-priority patent/WO2021214658A1/en
Publication of JP2023523218A publication Critical patent/JP2023523218A/ja
Publication of JP2023523218A5 publication Critical patent/JP2023523218A5/ja
Pending legal-status Critical Current

Links

JP2022563971A 2020-04-22 2021-04-20 ヘテロ二量体ヒトインターロイキン-15(hetIL-15)の医薬組成物及び医薬製品 Pending JP2023523218A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063013801P 2020-04-22 2020-04-22
US63/013,801 2020-04-22
PCT/IB2021/053254 WO2021214658A1 (en) 2020-04-22 2021-04-20 Pharmaceutical compositions and pharmaceutical products of heterodimeric human interleukin-15 (hetil-15)

Publications (2)

Publication Number Publication Date
JP2023523218A JP2023523218A (ja) 2023-06-02
JP2023523218A5 true JP2023523218A5 (enExample) 2024-04-30

Family

ID=75639945

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022563971A Pending JP2023523218A (ja) 2020-04-22 2021-04-20 ヘテロ二量体ヒトインターロイキン-15(hetIL-15)の医薬組成物及び医薬製品

Country Status (14)

Country Link
US (1) US20210330747A1 (enExample)
EP (1) EP4138782A1 (enExample)
JP (1) JP2023523218A (enExample)
KR (1) KR20230004655A (enExample)
CN (1) CN115443127A (enExample)
AR (1) AR122428A1 (enExample)
AU (1) AU2021260989A1 (enExample)
BR (1) BR112022020973A2 (enExample)
CA (1) CA3178895A1 (enExample)
CO (1) CO2022014867A2 (enExample)
IL (1) IL297326A (enExample)
MX (1) MX2022013352A (enExample)
TW (1) TW202214290A (enExample)
WO (1) WO2021214658A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117024749A (zh) 2019-06-28 2023-11-10 国立大学法人东京大学 蛋白质内包高分子胶束
TWI857396B (zh) * 2021-11-18 2024-10-01 大陸商山東先聲生物製藥有限公司 Il-15突變體融合蛋白藥物組合物
IL322075A (en) * 2023-02-14 2025-09-01 Akron Bioproducts Llc Pharmaceutical compositions of interleukin for use in vivo
CN117883565A (zh) * 2023-12-25 2024-04-16 中山大学 沙美特罗和pd-1抗体联用在制备治疗黑色素瘤的药物中的应用
WO2025206413A1 (en) * 2024-03-28 2025-10-02 The University Of Tokyo Protein-enclosing polymeric complexes

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6174666B1 (en) 1992-03-27 2001-01-16 The United States Of America As Represented By The Department Of Health And Human Services Method of eliminating inhibitory/instability regions from mRNA
EP3263581B2 (en) 2005-05-17 2025-07-09 University of Connecticut Compositions and methods for immunomodulation in an organism
NZ569541A (en) 2006-01-13 2012-05-25 Us Gov Health & Human Serv Codon optimized IL-15 and IL-15R-alpha genes for expression in mammalian cells
CN101743249B (zh) 2007-05-11 2017-08-08 阿尔托生物科学有限公司 融合分子与il‑15变异体
CA2711984A1 (en) * 2008-01-15 2009-07-23 Abbott Gmbh & Co. Kg Powdered protein compositions and methods of making same
CA2727953C (en) 2008-08-22 2017-05-16 Magna Seating Inc. Disc recliner with reduced backlash
US8915886B2 (en) * 2009-10-21 2014-12-23 Owen Mumford Limited Autoinjector
US8507222B2 (en) 2010-09-21 2013-08-13 Altor Bioscience Corporation Multimeric IL-15 soluble fusion molecules and methods of making and using same
EP3292873B1 (en) * 2013-02-22 2019-05-01 CureVac AG Combination of vaccination and inhibition of the pd-1 pathway
ES2811974T3 (es) * 2014-07-29 2021-03-15 Novartis Ag Regímenes de aumento escalonado de la dosis del heterodímero de il-15 e il-15ralfa para tratar afecciones
WO2017177063A1 (en) * 2016-04-06 2017-10-12 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Use of heterodimeric il-15 in adoptive cell transfer
WO2019019998A1 (zh) * 2017-07-25 2019-01-31 江苏恒瑞医药股份有限公司 一种il-15蛋白复合物药物组合物及其用途
EP3810171B1 (en) * 2018-06-22 2025-07-09 Cugene Inc. Novel interleukin-15 (1l-15) fusion proteins and uses thereof
JP2022530130A (ja) * 2019-04-26 2022-06-27 ルビウス セラピューティクス, インコーポレイテッド 除核赤血球細胞を含む緩衝組成物

Similar Documents

Publication Publication Date Title
JP2023523218A5 (enExample)
KR102864931B1 (ko) 인간화 항-전립선 특이적 막 항원(psma) 항체 약물 접합체
ES2633453T3 (es) Constructos de fusión de dominios líticos y métodos de preparación y utilización de los mismos
ES2872964T3 (es) Inmunoconjugado de IL-12
CN111328346B (zh) 基于人铁蛋白和蛋白酶可切割肽的融合蛋白及其作为化学治疗载体的用途
JP2020522494A5 (enExample)
ES3031307T3 (en) Proteins binding nkg2d, cd16 and egfr
JP2020138981A5 (enExample)
ES2773103T3 (es) Formulación de anticuerpos anti HER2
ES2526219T3 (es) Procedimientos de tratamiento de cáncer usando una inmunotoxina
BR112021002278A2 (pt) proteínas que ligam nkg2d, cd16 e um antígeno associado a tumor
JP2005508981A5 (enExample)
JP2010047601A (ja) カハラリドf
JP2009521206A5 (enExample)
RU2017146657A (ru) Пролекарства, содержащие коньюгат гиалуроновой кислоты, ликера и и двойного агониста glp-1глюкагона
US20110124564A1 (en) Nucleolin-binding peptides, nucleolin- binding lytic peptides, fusion constructs and methods of making and using same
KR20230010221A (ko) 암 치료를 위한 암 요법과 병용된 다량체 항-dr5 결합 분자의 용도
JP2019509311A5 (enExample)
ES2674491T3 (es) Nuevos fragmentos de anticuerpos, composiciones y usos de los mismos
JP7660523B2 (ja) アルカリリン酸塩に基づいた癌治療
WO2024153224A1 (zh) 一种含艾日布林衍生物药物偶联物的药物组合物
CN103347514A (zh) Fgfr1胞外域组合疗法
JP2011506436A (ja) 細胞傷害性tリンパ球抗原4(ctla4)に対する抗体と組み合わせられたアルファチモシンペプチドによる黒色腫の処置の方法
EP3996680B1 (en) Stable formulations of recombinant proteins
JP2023553561A (ja) Glp-1/glp-2デュアルアゴニストの医薬組成物