JP2023523218A5 - - Google Patents

Info

Publication number
JP2023523218A5
JP2023523218A5 JP2022563971A JP2022563971A JP2023523218A5 JP 2023523218 A5 JP2023523218 A5 JP 2023523218A5 JP 2022563971 A JP2022563971 A JP 2022563971A JP 2022563971 A JP2022563971 A JP 2022563971A JP 2023523218 A5 JP2023523218 A5 JP 2023523218A5
Authority
JP
Japan
Prior art keywords
approximately
cancer
weeks
storage
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022563971A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023523218A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2021/053254 external-priority patent/WO2021214658A1/en
Publication of JP2023523218A publication Critical patent/JP2023523218A/ja
Publication of JP2023523218A5 publication Critical patent/JP2023523218A5/ja
Pending legal-status Critical Current

Links

JP2022563971A 2020-04-22 2021-04-20 ヘテロ二量体ヒトインターロイキン-15(hetIL-15)の医薬組成物及び医薬製品 Pending JP2023523218A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063013801P 2020-04-22 2020-04-22
US63/013,801 2020-04-22
PCT/IB2021/053254 WO2021214658A1 (en) 2020-04-22 2021-04-20 Pharmaceutical compositions and pharmaceutical products of heterodimeric human interleukin-15 (hetil-15)

Publications (2)

Publication Number Publication Date
JP2023523218A JP2023523218A (ja) 2023-06-02
JP2023523218A5 true JP2023523218A5 (enExample) 2024-04-30

Family

ID=75639945

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022563971A Pending JP2023523218A (ja) 2020-04-22 2021-04-20 ヘテロ二量体ヒトインターロイキン-15(hetIL-15)の医薬組成物及び医薬製品

Country Status (14)

Country Link
US (1) US20210330747A1 (enExample)
EP (1) EP4138782A1 (enExample)
JP (1) JP2023523218A (enExample)
KR (1) KR20230004655A (enExample)
CN (1) CN115443127A (enExample)
AR (1) AR122428A1 (enExample)
AU (1) AU2021260989A1 (enExample)
BR (1) BR112022020973A2 (enExample)
CA (1) CA3178895A1 (enExample)
CO (1) CO2022014867A2 (enExample)
IL (1) IL297326A (enExample)
MX (1) MX2022013352A (enExample)
TW (1) TW202214290A (enExample)
WO (1) WO2021214658A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7083206B2 (ja) 2019-06-28 2022-06-10 国立大学法人 東京大学 タンパク質内包高分子ミセル
EP4434998A4 (en) * 2021-11-18 2025-06-18 Shandong Simcere Biopharmaceutical Co., Ltd. PHARMACEUTICAL COMPOSITION OF IL-15 MUTANT FUSION PROTEIN
KR20250144433A (ko) * 2023-02-14 2025-10-10 아크론 바이오프로덕츠 엘엘씨 생체내 이용을 위한 인터루킨 제형물
CN117883565A (zh) * 2023-12-25 2024-04-16 中山大学 沙美特罗和pd-1抗体联用在制备治疗黑色素瘤的药物中的应用
WO2025206413A1 (en) * 2024-03-28 2025-10-02 The University Of Tokyo Protein-enclosing polymeric complexes

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6174666B1 (en) 1992-03-27 2001-01-16 The United States Of America As Represented By The Department Of Health And Human Services Method of eliminating inhibitory/instability regions from mRNA
PL1899364T5 (pl) 2005-05-17 2024-12-09 University Of Connecticut Kompozycje i sposoby immunomodulacji w organizmie
EP1984505B1 (en) 2006-01-13 2019-12-25 The Government of the U.S.A., as repr. by the Secretary, Dept. of Health & Human Services, the Nat. Inst. of Health Codon optimized il-15 and il-15r-alpha genes for expression in mammalian cells
DK2160401T3 (da) 2007-05-11 2014-10-20 Altor Bioscience Corp Fusionsmolekyler og il-15-varianter
EP2249809A1 (en) * 2008-01-15 2010-11-17 Abbott GmbH & Co. KG Powdered protein compositions and methods of making same
CN102099221B (zh) 2008-08-22 2014-01-29 麦格纳座椅公司 具有减小空转的盘形调角器
KR101746881B1 (ko) * 2009-10-21 2017-06-14 오웬 멈포드 리미티드 오토인젝터
EP2619229B1 (en) 2010-09-21 2016-04-06 Altor BioScience Corporation Multimeric il-15 soluble fusion molecules and methods of making and using same
BR122021025267B1 (pt) * 2013-02-22 2023-12-05 Curevac Ag Partes de kit e composição farmacêutica compreendendo um inibidor da via de pd-1
WO2016018920A1 (en) * 2014-07-29 2016-02-04 Admune Therapeutics Llc Il-15 and il-15ralpha heterodimer dose escalation regimens for treating conditions
WO2017177063A1 (en) * 2016-04-06 2017-10-12 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Use of heterodimeric il-15 in adoptive cell transfer
PL3639845T3 (pl) * 2017-07-25 2023-10-23 Jiangsu Hengrui Medicine Co., Ltd. Kompozycja farmaceutyczna zawierająca kompleks białka il-15 i jej zastosowania
CA3102821A1 (en) * 2018-06-22 2019-12-26 Cugene Inc. Novel interleukin-15 (1l-15) fusion proteins and uses thereof
KR20220005028A (ko) * 2019-04-26 2022-01-12 루비우스 테라퓨틱스, 아이엔씨. 탈핵 적혈구를 포함하는 조성물

Similar Documents

Publication Publication Date Title
KR102864931B1 (ko) 인간화 항-전립선 특이적 막 항원(psma) 항체 약물 접합체
ES2706428T3 (es) Inmunoconjugado de IL-12
ES2633453T3 (es) Constructos de fusión de dominios líticos y métodos de preparación y utilización de los mismos
CN111328346B (zh) 基于人铁蛋白和蛋白酶可切割肽的融合蛋白及其作为化学治疗载体的用途
ES3031307T3 (en) Proteins binding nkg2d, cd16 and egfr
ES2774296T3 (es) Terapias de combinación para tratar cánceres quimiorresistentes
JP2005508981A5 (enExample)
JP2010047601A (ja) カハラリドf
RU2017146657A (ru) Пролекарства, содержащие коньюгат гиалуроновой кислоты, ликера и и двойного агониста glp-1глюкагона
US20110124564A1 (en) Nucleolin-binding peptides, nucleolin- binding lytic peptides, fusion constructs and methods of making and using same
KR20230010221A (ko) 암 치료를 위한 암 요법과 병용된 다량체 항-dr5 결합 분자의 용도
JP2020509737A5 (enExample)
CN103347514B (zh) Fgfr1胞外域组合疗法
TW201907947A (zh) 一種il-15蛋白質複合物醫藥組成物及其用途
ES2674491T3 (es) Nuevos fragmentos de anticuerpos, composiciones y usos de los mismos
JP7660523B2 (ja) アルカリリン酸塩に基づいた癌治療
JP2004512370A5 (enExample)
ES2930351T3 (es) Un dímero de IL-22 para su uso en el tratamiento de enterocolitis necrosante
WO2024153224A1 (zh) 一种含艾日布林衍生物药物偶联物的药物组合物
EP3996680B1 (en) Stable formulations of recombinant proteins
JP2023553562A (ja) Glp-1/glp-2デュアルアゴニストの医薬組成物
CN116710114A (zh) Glp-1/glp-2双重激动剂的药物组合物
AU2015216941B2 (en) Polypeptide fragments of 168A-T2 and compositions comprising them for use in treating cancer
JP2023512337A (ja) インターロイキン-12とフィブロネクチンのエクストラドメインbに結合する抗体とを含む組換えタンパク質を含む組成物の投与単位およびレジメン、使用、方法または製剤
WO2024179453A1 (zh) 重组人源化抗Nectin-4单抗-MMAE偶联药物的药物组合物