JP2023521491A5 - - Google Patents

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Publication number
JP2023521491A5
JP2023521491A5 JP2022562985A JP2022562985A JP2023521491A5 JP 2023521491 A5 JP2023521491 A5 JP 2023521491A5 JP 2022562985 A JP2022562985 A JP 2022562985A JP 2022562985 A JP2022562985 A JP 2022562985A JP 2023521491 A5 JP2023521491 A5 JP 2023521491A5
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JP
Japan
Prior art keywords
cysteine
glutamine
lysine
alanine
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022562985A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023521491A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/KR2021/004961 external-priority patent/WO2021215801A1/ko
Publication of JP2023521491A publication Critical patent/JP2023521491A/ja
Publication of JP2023521491A5 publication Critical patent/JP2023521491A5/ja
Pending legal-status Critical Current

Links

JP2022562985A 2020-04-20 2021-04-20 グルカゴン、glp-1及びgip受容体の全てに対して活性を有する三重活性体又はその結合体を含む高脂血症の予防又は治療用薬学的組成物及び予防又は治療方法 Pending JP2023521491A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20200047733 2020-04-20
KR10-2020-0047733 2020-04-20
PCT/KR2021/004961 WO2021215801A1 (ko) 2020-04-20 2021-04-20 글루카곤, glp-1 및 gip 수용체 모두에 활성을 갖는 삼중 활성체 또는 이의 결합체를 포함하는 고지혈증 예방 또는 치료용 약학적 조성물 및 예방 또는 치료 방법

Publications (2)

Publication Number Publication Date
JP2023521491A JP2023521491A (ja) 2023-05-24
JP2023521491A5 true JP2023521491A5 (https=) 2024-05-07

Family

ID=78232790

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022562985A Pending JP2023521491A (ja) 2020-04-20 2021-04-20 グルカゴン、glp-1及びgip受容体の全てに対して活性を有する三重活性体又はその結合体を含む高脂血症の予防又は治療用薬学的組成物及び予防又は治療方法

Country Status (12)

Country Link
US (1) US20230158117A1 (https=)
EP (1) EP4140496A4 (https=)
JP (1) JP2023521491A (https=)
KR (1) KR20210129614A (https=)
CN (1) CN115916238A (https=)
AU (1) AU2021203645B2 (https=)
BR (1) BR112022020531A2 (https=)
CA (1) CA3174423A1 (https=)
IL (1) IL296960A (https=)
MX (1) MX2022012847A (https=)
TW (1) TW202203963A (https=)
WO (1) WO2021215801A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230095665A (ko) * 2021-12-22 2023-06-29 한미약품 주식회사 간 표적 약물 및 이의 용도
KR20250177375A (ko) * 2024-06-13 2025-12-23 한미약품 주식회사 Glp-1, gip, 및 글루카곤 수용체 모두에 활성을 갖는 삼중 활성체 및 이를 포함하는 지질 대사 질환 예방 또는 치료용 약학적 조성물
WO2026082095A1 (en) * 2024-10-17 2026-04-23 Innovent Biologics (Suzhou) Co., Ltd. Compounds for treating metabolic disorders

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6096871A (en) 1995-04-14 2000-08-01 Genentech, Inc. Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life
JP4046354B2 (ja) 1996-03-18 2008-02-13 ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム 増大した半減期を有する免疫グロブリン様ドメイン
EP1667724A2 (en) * 2003-09-19 2006-06-14 Novo Nordisk A/S Albumin-binding derivatives of therapeutic peptides
JP2009534423A (ja) * 2006-04-20 2009-09-24 アムジェン インコーポレイテッド Glp−1化合物
AU2013366692B2 (en) * 2012-12-21 2017-11-23 Sanofi Dual GLP1/GIP or trigonal GLP1/GIP/Glucagon agonists
CN105829339B (zh) * 2013-11-06 2021-03-12 西兰制药公司 胰高血糖素-glp-1-gip三重激动剂化合物
SG11201805586SA (en) * 2015-12-31 2018-07-30 Hanmi Pharmaceutical Co Ltd Triple glucagon/glp-1/gip receptor agonist
EP3479841A4 (en) * 2016-06-29 2020-03-04 Hanmi Pharm. Co., Ltd. GLUCAGON DERIVATIVE, CONJUGATE THEREOF, COMPOSITION THEREOF AND THERAPEUTIC USE THEREOF
TW201833131A (zh) * 2016-12-02 2018-09-16 法商賽諾菲公司 作為胜肽類glp1/升糖素/gip受體促效劑之新化合物
SG11202001283PA (en) * 2017-08-16 2020-03-30 Dong A St Co Ltd Acylated oxyntomodulin peptide analog

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