IL296960A - Composition for prevention or treatment of hyperlipidemia comprising trigonal glucagon/glp-1/gip receptor agonist or conjugate thereof and method using the same - Google Patents
Composition for prevention or treatment of hyperlipidemia comprising trigonal glucagon/glp-1/gip receptor agonist or conjugate thereof and method using the sameInfo
- Publication number
- IL296960A IL296960A IL296960A IL29696022A IL296960A IL 296960 A IL296960 A IL 296960A IL 296960 A IL296960 A IL 296960A IL 29696022 A IL29696022 A IL 29696022A IL 296960 A IL296960 A IL 296960A
- Authority
- IL
- Israel
- Prior art keywords
- cysteine
- glutamine
- lysine
- alanine
- glutamic acid
- Prior art date
Links
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Landscapes
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- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
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- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20200047733 | 2020-04-20 | ||
| PCT/KR2021/004961 WO2021215801A1 (ko) | 2020-04-20 | 2021-04-20 | 글루카곤, glp-1 및 gip 수용체 모두에 활성을 갖는 삼중 활성체 또는 이의 결합체를 포함하는 고지혈증 예방 또는 치료용 약학적 조성물 및 예방 또는 치료 방법 |
Publications (1)
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|---|---|
| IL296960A true IL296960A (en) | 2022-12-01 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL296960A IL296960A (en) | 2020-04-20 | 2021-04-20 | Composition for prevention or treatment of hyperlipidemia comprising trigonal glucagon/glp-1/gip receptor agonist or conjugate thereof and method using the same |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20230158117A1 (https=) |
| EP (1) | EP4140496A4 (https=) |
| JP (1) | JP2023521491A (https=) |
| KR (1) | KR20210129614A (https=) |
| CN (1) | CN115916238A (https=) |
| AU (1) | AU2021203645B2 (https=) |
| BR (1) | BR112022020531A2 (https=) |
| CA (1) | CA3174423A1 (https=) |
| IL (1) | IL296960A (https=) |
| MX (1) | MX2022012847A (https=) |
| TW (1) | TW202203963A (https=) |
| WO (1) | WO2021215801A1 (https=) |
Families Citing this family (3)
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| KR20230095665A (ko) * | 2021-12-22 | 2023-06-29 | 한미약품 주식회사 | 간 표적 약물 및 이의 용도 |
| KR20250177375A (ko) * | 2024-06-13 | 2025-12-23 | 한미약품 주식회사 | Glp-1, gip, 및 글루카곤 수용체 모두에 활성을 갖는 삼중 활성체 및 이를 포함하는 지질 대사 질환 예방 또는 치료용 약학적 조성물 |
| WO2026082095A1 (en) * | 2024-10-17 | 2026-04-23 | Innovent Biologics (Suzhou) Co., Ltd. | Compounds for treating metabolic disorders |
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| US6096871A (en) | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
| JP4046354B2 (ja) | 1996-03-18 | 2008-02-13 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | 増大した半減期を有する免疫グロブリン様ドメイン |
| EP1667724A2 (en) * | 2003-09-19 | 2006-06-14 | Novo Nordisk A/S | Albumin-binding derivatives of therapeutic peptides |
| JP2009534423A (ja) * | 2006-04-20 | 2009-09-24 | アムジェン インコーポレイテッド | Ｇｌｐ−１化合物 |
| AU2013366692B2 (en) * | 2012-12-21 | 2017-11-23 | Sanofi | Dual GLP1/GIP or trigonal GLP1/GIP/Glucagon agonists |
| CN105829339B (zh) * | 2013-11-06 | 2021-03-12 | 西兰制药公司 | 胰高血糖素-glp-1-gip三重激动剂化合物 |
| SG11201805586SA (en) * | 2015-12-31 | 2018-07-30 | Hanmi Pharmaceutical Co Ltd | Triple glucagon/glp-1/gip receptor agonist |
| EP3479841A4 (en) * | 2016-06-29 | 2020-03-04 | Hanmi Pharm. Co., Ltd. | GLUCAGON DERIVATIVE, CONJUGATE THEREOF, COMPOSITION THEREOF AND THERAPEUTIC USE THEREOF |
| TW201833131A (zh) * | 2016-12-02 | 2018-09-16 | 法商賽諾菲公司 | 作為胜肽類ｇｌｐ１／升糖素／ｇｉｐ受體促效劑之新化合物 |
| SG11202001283PA (en) * | 2017-08-16 | 2020-03-30 | Dong A St Co Ltd | Acylated oxyntomodulin peptide analog |
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2021
- 2021-04-20 EP EP21793803.4A patent/EP4140496A4/en active Pending
- 2021-04-20 CN CN202180038989.3A patent/CN115916238A/zh active Pending
- 2021-04-20 TW TW110114173A patent/TW202203963A/zh unknown
- 2021-04-20 JP JP2022562985A patent/JP2023521491A/ja active Pending
- 2021-04-20 IL IL296960A patent/IL296960A/en unknown
- 2021-04-20 KR KR1020210051337A patent/KR20210129614A/ko active Pending
- 2021-04-20 CA CA3174423A patent/CA3174423A1/en active Pending
- 2021-04-20 WO PCT/KR2021/004961 patent/WO2021215801A1/ko not_active Ceased
- 2021-04-20 MX MX2022012847A patent/MX2022012847A/es unknown
- 2021-04-20 BR BR112022020531A patent/BR112022020531A2/pt unknown
- 2021-04-20 AU AU2021203645A patent/AU2021203645B2/en active Active
- 2021-04-20 US US17/917,846 patent/US20230158117A1/en active Pending
Also Published As
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| TW202203963A (zh) | 2022-02-01 |
| AU2021203645A1 (en) | 2021-11-04 |
| WO2021215801A1 (ko) | 2021-10-28 |
| BR112022020531A2 (pt) | 2022-12-06 |
| EP4140496A4 (en) | 2024-05-22 |
| KR20210129614A (ko) | 2021-10-28 |
| EP4140496A1 (en) | 2023-03-01 |
| US20230158117A1 (en) | 2023-05-25 |
| CA3174423A1 (en) | 2021-10-28 |
| CN115916238A (zh) | 2023-04-04 |
| JP2023521491A (ja) | 2023-05-24 |
| MX2022012847A (es) | 2022-11-07 |
| AU2021203645B2 (en) | 2024-06-27 |
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