JP2023520412A5 - - Google Patents
Info
- Publication number
- JP2023520412A5 JP2023520412A5 JP2022559619A JP2022559619A JP2023520412A5 JP 2023520412 A5 JP2023520412 A5 JP 2023520412A5 JP 2022559619 A JP2022559619 A JP 2022559619A JP 2022559619 A JP2022559619 A JP 2022559619A JP 2023520412 A5 JP2023520412 A5 JP 2023520412A5
- Authority
- JP
- Japan
- Prior art keywords
- mhci
- mhc
- item
- monomer
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063003177P | 2020-03-31 | 2020-03-31 | |
| US63/003,177 | 2020-03-31 | ||
| PCT/US2021/025167 WO2021202727A2 (en) | 2020-03-31 | 2021-03-31 | Barcodable exchangeable peptide-mhc multimer libraries |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023520412A JP2023520412A (ja) | 2023-05-17 |
| JP2023520412A5 true JP2023520412A5 (https=) | 2024-04-11 |
| JP7846628B2 JP7846628B2 (ja) | 2026-04-15 |
Family
ID=75660333
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022559619A Active JP7846628B2 (ja) | 2020-03-31 | 2021-03-31 | バーコード化可能な交換可能ペプチド－ｍｈｃ多量体ライブラリー |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230287394A1 (https=) |
| EP (1) | EP4126923A2 (https=) |
| JP (1) | JP7846628B2 (https=) |
| CN (1) | CN115776987A (https=) |
| AU (1) | AU2021248941A1 (https=) |
| CA (1) | CA3176448A1 (https=) |
| IL (1) | IL296789A (https=) |
| WO (1) | WO2021202727A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114644706B (zh) * | 2022-02-16 | 2024-04-09 | 国家纳米科学中心 | 基于DNA纳米技术的pMHC多聚体制备方法及其应用 |
| AU2023314797A1 (en) | 2022-07-29 | 2024-12-12 | Repertoire Immune Medicines, Inc. | T cell epitopes associated with type 1 diabetes |
| WO2025072849A1 (en) | 2023-09-29 | 2025-04-03 | Repertoire Immune Medicines, Inc. | Mhc-presentable peptides associated with type 1 diabetes |
| WO2025137580A1 (en) * | 2023-12-22 | 2025-06-26 | Antiger Therapeutics, Inc. | Class ii hla with inter-chain disulfide bond |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE30985E (en) | 1978-01-01 | 1982-06-29 | Serum-free cell culture media | |
| NO155316C (no) | 1982-04-23 | 1987-03-11 | Sintef | Fremgangsmaate for fremstilling av magnetiske polymerpartikler. |
| US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
| US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
| US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
| US5672502A (en) | 1985-06-28 | 1997-09-30 | Celltech Therapeutics Limited | Animal cell culture |
| US4927762A (en) | 1986-04-01 | 1990-05-22 | Cell Enterprises, Inc. | Cell culture medium with antioxidant |
| US6048728A (en) | 1988-09-23 | 2000-04-11 | Chiron Corporation | Cell culture medium for enhanced cell growth, culture longevity, and product expression |
| FR2646437B1 (fr) | 1989-04-28 | 1991-08-30 | Transgene Sa | Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant |
| US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
| US5525491A (en) | 1991-02-27 | 1996-06-11 | Creative Biomolecules, Inc. | Serine-rich peptide linkers |
| AU3220593A (en) | 1991-11-19 | 1993-06-15 | Anergen, Inc. | Soluble mhc molecules and their uses |
| DE4237113B4 (de) | 1992-11-03 | 2006-10-12 | "Iba Gmbh" | Peptide und deren Fusionsproteine, Expressionsvektor und Verfahren zur Herstellung eines Fusionsproteins |
| DK0752248T3 (da) | 1992-11-13 | 2000-11-13 | Idec Pharma Corp | Terapeutisk anvendelse af kimæriske og radioaktivt mærkede antistoffer mod humant B-lymfocytbegrænset differentieringsantig |
| DE19641876B4 (de) | 1996-10-10 | 2011-09-29 | Iba Gmbh | Streptavidinmuteine |
| DE10247014A1 (de) * | 2002-10-09 | 2004-04-22 | Erfle, Volker, Prof. Priv.-Doz. Dr. | MHC-Multimere |
| GB0226227D0 (en) * | 2002-11-09 | 2002-12-18 | Avidex Ltd | Receptors |
| WO2005047902A1 (en) | 2003-11-03 | 2005-05-26 | Beckman Coulter, Inc. | Solution-based methods for detecting mhc-binding peptides |
| GB2422834B8 (en) * | 2005-02-04 | 2007-01-04 | Proimmune Ltd | MHC oligomer and method of making the same |
| WO2006136763A1 (en) * | 2005-06-20 | 2006-12-28 | Medigene Limited | Synthetic ligands of peptide-mhc complexes, or cd1-antigen complexes |
| GB2430256B (en) | 2005-09-19 | 2008-06-25 | Proimmune Ltd | A method of screening MHC molecules |
| EP3620465B1 (en) * | 2007-07-03 | 2025-02-19 | Dako Denmark A/S | Improved methods for generation, labeling and use of mhc multimers |
| TWI496582B (zh) | 2008-11-24 | 2015-08-21 | 必治妥美雅史谷比公司 | 雙重專一性之ｅｇｆｒ／ｉｇｆｉｒ結合分子 |
| EP2396000A1 (en) | 2009-02-11 | 2011-12-21 | Bristol-Myers Squibb Company | Combination vegfr2 therapy with temozolomide |
| EP2558491B1 (en) | 2010-04-13 | 2018-07-04 | Bristol-Myers Squibb Company | Fibronectin based scaffold domain proteins that bind pcsk9 |
| CN102296807B (zh) | 2011-06-27 | 2013-06-05 | 中国葛洲坝集团股份有限公司 | 管、槽圆弧形混凝土底板轻便滑模 |
| JP6364352B2 (ja) * | 2012-01-06 | 2018-07-25 | オレゴン ヘルス アンド サイエンス ユニバーシティ | 部分的ｍｈｃコンストラクト及びその使用方法 |
| US10816554B2 (en) * | 2014-04-04 | 2020-10-27 | The Board Of Trustees Of The Leland Stanford Junior University | Ligand discovery for T cell receptors |
| EP2952520A1 (en) * | 2014-06-06 | 2015-12-09 | Stichting Sanquin Bloedvoorziening | Cleavage and exchange of major histocompatibility complex ligands employing azobenzene-containing peptides. |
| SG10202005892SA (en) * | 2014-06-06 | 2020-07-29 | Herlev Hospital | Determining antigen recognition through barcoding of mhc multimers |
| WO2015200541A1 (en) | 2014-06-24 | 2015-12-30 | Bio-Rad Laboratories, Inc. | Digital pcr barcoding |
| SG11202007686VA (en) * | 2018-02-12 | 2020-09-29 | 10X Genomics Inc | Methods characterizing multiple analytes from individual cells or cell populations |
| WO2019238939A1 (en) * | 2018-06-15 | 2019-12-19 | F. Hoffmann-La Roche Ag | A system for identification of antigens recognized by t cell receptors expressed on tumor infiltrating lymphocytes |
| US20220073908A1 (en) * | 2019-01-04 | 2022-03-10 | Repertoire Immune Medicines, Inc. | Methods of producing high diversity peptide libraries and promoting protein folding |
-
2021
- 2021-03-31 WO PCT/US2021/025167 patent/WO2021202727A2/en not_active Ceased
- 2021-03-31 AU AU2021248941A patent/AU2021248941A1/en active Pending
- 2021-03-31 CA CA3176448A patent/CA3176448A1/en active Pending
- 2021-03-31 EP EP21721278.6A patent/EP4126923A2/en active Pending
- 2021-03-31 IL IL296789A patent/IL296789A/en unknown
- 2021-03-31 CN CN202180039282.4A patent/CN115776987A/zh active Pending
- 2021-03-31 US US17/995,074 patent/US20230287394A1/en active Pending
- 2021-03-31 JP JP2022559619A patent/JP7846628B2/ja active Active
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