JP2023517206A5 - - Google Patents

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Publication number
JP2023517206A5
JP2023517206A5 JP2022553675A JP2022553675A JP2023517206A5 JP 2023517206 A5 JP2023517206 A5 JP 2023517206A5 JP 2022553675 A JP2022553675 A JP 2022553675A JP 2022553675 A JP2022553675 A JP 2022553675A JP 2023517206 A5 JP2023517206 A5 JP 2023517206A5
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JP
Japan
Prior art keywords
compound
cancer
pharmaceutically acceptable
linker
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022553675A
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English (en)
Japanese (ja)
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JP2023517206A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/021201 external-priority patent/WO2021178887A1/en
Publication of JP2023517206A publication Critical patent/JP2023517206A/ja
Publication of JP2023517206A5 publication Critical patent/JP2023517206A5/ja
Pending legal-status Critical Current

Links

JP2022553675A 2020-03-06 2021-03-05 Car-t細胞活性を改変するための方法、化合物、および組成物 Pending JP2023517206A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062986349P 2020-03-06 2020-03-06
US62/986,349 2020-03-06
PCT/US2021/021201 WO2021178887A1 (en) 2020-03-06 2021-03-05 Methods, compounds, and compositions for modifying car-t cell activity

Publications (2)

Publication Number Publication Date
JP2023517206A JP2023517206A (ja) 2023-04-24
JP2023517206A5 true JP2023517206A5 (https=) 2024-03-14

Family

ID=77613014

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022553675A Pending JP2023517206A (ja) 2020-03-06 2021-03-05 Car-t細胞活性を改変するための方法、化合物、および組成物

Country Status (10)

Country Link
US (1) US20240058458A1 (https=)
EP (1) EP4114471A4 (https=)
JP (1) JP2023517206A (https=)
KR (1) KR20220153027A (https=)
CN (1) CN115551555A (https=)
AU (1) AU2021231887A1 (https=)
BR (1) BR112022017815A2 (https=)
CA (1) CA3169152A1 (https=)
IL (1) IL296176A (https=)
WO (1) WO2021178887A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4282419A1 (en) 2012-12-20 2023-11-29 Purdue Research Foundation Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
EP3439675A4 (en) 2016-04-08 2019-12-18 Purdue Research Foundation METHOD AND COMPOSITIONS FOR CAR-T CELL THERAPY
WO2018160622A1 (en) 2017-02-28 2018-09-07 Endocyte, Inc. Compositions and methods for car t cell therapy
US11311576B2 (en) 2018-01-22 2022-04-26 Seattle Children's Hospital Methods of use for CAR T cells
AU2019225174B2 (en) 2018-02-23 2025-11-20 Endocyte, Inc. Sequencing method for CAR T cell therapy
CN115210252A (zh) 2020-02-04 2022-10-18 西雅图儿童医院(Dba西雅图儿童研究所) 抗二硝基苯酚的嵌合抗原受体
EP4644537A1 (en) 2024-04-30 2025-11-05 ConvEyXo Targeted extracellular vesicle
CN121449625B (zh) * 2026-01-06 2026-03-27 中国药科大学 一种靶向vista免疫检查点的荧光素探针分子及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4282419A1 (en) * 2012-12-20 2023-11-29 Purdue Research Foundation Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
US20160166679A1 (en) * 2014-12-12 2016-06-16 Purdue Research Foundation Method of treatment using folate conjugates and tyrosine kinase inhibitors
BR112017013981A2 (pt) * 2015-01-26 2018-01-02 Cellectis receptores antigênicos quiméricos com uma única cadeia específicos anti-cll1 (sccars) para imunoterapia de câncer
US11091546B2 (en) * 2015-04-15 2021-08-17 The Scripps Research Institute Optimized PNE-based chimeric receptor T cell switches and uses thereof
WO2017024318A1 (en) * 2015-08-06 2017-02-09 Dana-Farber Cancer Institute, Inc. Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses
CN112543651B (zh) * 2018-08-07 2023-06-02 普渡研究基金会 使car t细胞恢复活力

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