JP2023516381A5 - - Google Patents

Info

Publication number
JP2023516381A5
JP2023516381A5 JP2022552782A JP2022552782A JP2023516381A5 JP 2023516381 A5 JP2023516381 A5 JP 2023516381A5 JP 2022552782 A JP2022552782 A JP 2022552782A JP 2022552782 A JP2022552782 A JP 2022552782A JP 2023516381 A5 JP2023516381 A5 JP 2023516381A5
Authority
JP
Japan
Prior art keywords
cancer
amino acid
alkyl
formula
pyridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022552782A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023516381A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/KR2021/002622 external-priority patent/WO2021177721A1/ko
Publication of JP2023516381A publication Critical patent/JP2023516381A/ja
Publication of JP2023516381A5 publication Critical patent/JP2023516381A5/ja
Pending legal-status Critical Current

Links

JP2022552782A 2020-03-03 2021-03-03 Kras変異および活性化ronが存在する癌の予防または治療のための医薬組成物 Pending JP2023516381A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2020-0026381 2020-03-03
KR20200026381 2020-03-03
PCT/KR2021/002622 WO2021177721A1 (ko) 2020-03-03 2021-03-03 Kras 돌연변이 및 활성화된 ron이 존재하는 암의 예방 또는 치료용 약학 조성물

Publications (2)

Publication Number Publication Date
JP2023516381A JP2023516381A (ja) 2023-04-19
JP2023516381A5 true JP2023516381A5 (enExample) 2024-03-12

Family

ID=77612768

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022552782A Pending JP2023516381A (ja) 2020-03-03 2021-03-03 Kras変異および活性化ronが存在する癌の予防または治療のための医薬組成物

Country Status (6)

Country Link
US (1) US20230099204A1 (enExample)
EP (1) EP4115887A4 (enExample)
JP (1) JP2023516381A (enExample)
KR (1) KR20210111711A (enExample)
CN (1) CN115209900A (enExample)
WO (1) WO2021177721A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019217307A1 (en) 2018-05-07 2019-11-14 Mirati Therapeutics, Inc. Kras g12c inhibitors
EA202190749A1 (ru) 2018-09-10 2021-07-09 Мирати Терапьютикс, Инк. Способы комбинированной терапии
EP3849535A4 (en) 2018-09-10 2022-06-29 Mirati Therapeutics, Inc. Combination therapies
JP2022500385A (ja) 2018-09-10 2022-01-04 ミラティ セラピューティクス, インコーポレイテッド 組み合わせ療法
EP3849537B1 (en) 2018-09-10 2024-10-23 Mirati Therapeutics, Inc. Combination therapies
MX2021002804A (es) 2018-12-05 2021-07-15 Mirati Therapeutics Inc Terapias de combinacion.
EP3908283A4 (en) 2019-01-10 2022-10-12 Mirati Therapeutics, Inc. KRAS G12C INHIBITORS
US20220235064A1 (en) * 2019-08-02 2022-07-28 Wellmarker Bio Co., Ltd. Oxo-pyridine fusion ring derivative and pharmaceutical composition comprising same
MX2022002465A (es) 2019-08-29 2022-05-19 Mirati Therapeutics Inc Inhibidores de kras g12d.
WO2021061749A1 (en) 2019-09-24 2021-04-01 Mirati Therapeutics, Inc. Combination therapies
PH12022551513A1 (en) 2019-12-20 2023-04-24 Mirati Therapeutics Inc Sos1 inhibitors
EP4210833A4 (en) 2020-09-11 2024-09-11 Mirati Therapeutics, Inc. CRYSTALLINE FORMS OF A KRAS G12C INHIBITOR
JP2023553492A (ja) 2020-12-15 2023-12-21 ミラティ セラピューティクス, インコーポレイテッド アザキナゾリン汎KRas阻害剤
EP4262803A4 (en) 2020-12-16 2025-03-12 Mirati Therapeutics, Inc. Tetrahydropyridopyrimidine pan-kras inhibitors
KR20230144483A (ko) * 2022-04-06 2023-10-16 웰마커바이오 주식회사 Ron 돌연변이와 관련된 두경부암 예방 또는 치료용 약학 조성물

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2089364T1 (sl) 2006-11-08 2013-10-30 Bristol-Myers Squibb Company Spojine piridinona
CN102816175B (zh) * 2011-06-09 2015-12-16 上海汇伦生命科技有限公司 一种杂环并吡啶酮类化合物,其中间体、制备方法和用途
RU2014102935A (ru) 2011-08-02 2015-09-10 Пфайзер Инк. Кризотиниб для применения в лечении рака
EP2836482B1 (en) * 2012-04-10 2019-12-25 The Regents of The University of California Compositions and methods for treating cancer
KR101350006B1 (ko) * 2012-09-06 2014-02-13 씨제이제일제당 (주) 피리돈 유도체를 포함하는 단백질 키나제 억제제
US11564915B2 (en) 2013-04-04 2023-01-31 Exelixis, Inc. Cabozantinib dosage form and use in the treatment of cancer
CN107517590B (zh) * 2014-07-29 2021-11-12 威马克生物有限公司 与表皮生长因子受体-靶制剂有关的感受性预测用新型生物标志物及其用途
US11946934B2 (en) * 2014-09-03 2024-04-02 Wellmarker Bio Co., Ltd. Biomarker for predicting the sensitivity to a protein kinase inhibitor and a use thereof
WO2019182274A1 (en) * 2018-03-08 2019-09-26 Wellmarker Bio Co., Ltd. Thienopyridine derivatives and pharmaceutical composition comprising same
US20220235064A1 (en) * 2019-08-02 2022-07-28 Wellmarker Bio Co., Ltd. Oxo-pyridine fusion ring derivative and pharmaceutical composition comprising same
EP3819300A4 (en) * 2019-09-06 2021-11-24 Wellmarker Bio Co., Ltd. THERAPEUTIC COMPOSITION BASED ON BIOMARKERS
JP2023513675A (ja) * 2020-02-06 2023-04-03 ウェルマーカー・バイオ・カンパニー・リミテッド Kras変異に関連する癌の予防または治療のための医薬組成物

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