JP2023516300A5 - - Google Patents

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Publication number
JP2023516300A5
JP2023516300A5 JP2022551637A JP2022551637A JP2023516300A5 JP 2023516300 A5 JP2023516300 A5 JP 2023516300A5 JP 2022551637 A JP2022551637 A JP 2022551637A JP 2022551637 A JP2022551637 A JP 2022551637A JP 2023516300 A5 JP2023516300 A5 JP 2023516300A5
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JP
Japan
Prior art keywords
agonist
population
tils
optionally
tumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022551637A
Other languages
English (en)
Japanese (ja)
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JP2023516300A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/019861 external-priority patent/WO2021173964A1/en
Publication of JP2023516300A publication Critical patent/JP2023516300A/ja
Publication of JP2023516300A5 publication Critical patent/JP2023516300A5/ja
Pending legal-status Critical Current

Links

JP2022551637A 2020-02-28 2021-02-26 腫瘍浸潤リンパ球の活性化及び増殖のための方法 Pending JP2023516300A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202062983416P 2020-02-28 2020-02-28
US62/983,416 2020-02-28
US202063074841P 2020-09-04 2020-09-04
US63/074,841 2020-09-04
US202163144853P 2021-02-02 2021-02-02
US63/144,853 2021-02-02
PCT/US2021/019861 WO2021173964A1 (en) 2020-02-28 2021-02-26 Methods for activation and expansion of tumor infiltrating lymphocytes

Publications (2)

Publication Number Publication Date
JP2023516300A JP2023516300A (ja) 2023-04-19
JP2023516300A5 true JP2023516300A5 (https=) 2024-01-26

Family

ID=77491997

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022551637A Pending JP2023516300A (ja) 2020-02-28 2021-02-26 腫瘍浸潤リンパ球の活性化及び増殖のための方法

Country Status (8)

Country Link
US (1) US20230108584A1 (https=)
EP (1) EP4110352A4 (https=)
JP (1) JP2023516300A (https=)
KR (1) KR20230034198A (https=)
CN (1) CN116096865A (https=)
AU (1) AU2021228701A1 (https=)
CA (1) CA3168932A1 (https=)
WO (1) WO2021173964A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109536444B (zh) * 2018-12-11 2022-06-28 吉林省拓华生物科技有限公司 一种适用于恶性实体瘤肿瘤浸润t淋巴细胞的分离诱导方法
CA3158133A1 (en) 2020-04-28 2021-11-04 Lyell Immunopharma, Inc. Methods for culturing cells
EP4239059A4 (en) 2020-11-19 2024-05-15 Suzhou Grit Biotechnology Co., Ltd. METHOD FOR CULTIVATION OF TUMOR INFILTRATING LYMPHOCYTES AND USE THEREOF
US12144827B2 (en) 2021-02-25 2024-11-19 Lyell Immunopharma, Inc. ROR1 targeting chimeric antigen receptor
CN117043321A (zh) * 2021-04-23 2023-11-10 苏州沙砾生物科技有限公司 一种修饰的肿瘤浸润淋巴细胞及其用途
JP2024547000A (ja) * 2021-12-17 2024-12-26 インスティル バイオ インコーポレイテッド 腫瘍浸潤リンパ球の処理
CN118414422A (zh) * 2021-12-30 2024-07-30 苏州沙砾生物科技有限公司 一种修饰的肿瘤浸润淋巴细胞及其用途
WO2023143515A1 (zh) * 2022-01-29 2023-08-03 苏州沙砾生物科技有限公司 一种修饰的肿瘤浸润淋巴细胞及其用途
WO2024020531A1 (en) * 2022-07-21 2024-01-25 Tract Therapeutics, Inc. Immune cell expansion and uses thereof
EP4694917A1 (en) * 2023-04-12 2026-02-18 Beam Therapeutics Inc. Modified immune effector cells with improved efficacy
CN117417894A (zh) * 2023-09-15 2024-01-19 毕诺济(上海)生物技术有限公司 敲除Roquin-1和/或Regnase-1基因的肿瘤浸润淋巴细胞及其应用
WO2025092690A1 (zh) * 2023-10-30 2025-05-08 苏州沙砾生物科技有限公司 一种修饰的细胞及其用途
WO2025096638A2 (en) * 2023-10-30 2025-05-08 Turnstone Biologics Corp. Genetically modified tumor infilitrating lymphocytes and methods of producing and using the same
WO2025106513A1 (en) * 2023-11-13 2025-05-22 KSQ Therapeutics, Inc. Methods for producing edited tumor infiltrating lymphocytes

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2711418B1 (en) * 2012-09-25 2017-08-23 Miltenyi Biotec GmbH Method for polyclonal stimulation of T cells by flexible nanomatrices
EP2961415B1 (en) * 2013-03-01 2021-01-06 The United States of America, as represented by The Secretary, Department of Health and Human Services Methods of producing enriched populations of tumor-reactive t cells from tumor
WO2015157636A1 (en) * 2014-04-10 2015-10-15 H. Lee Moffitt Cancer Center And Research Institute, Inc. Enhanced expansion of tumor-infiltrating lymphocytes for adoptive cell therapy
EP3322424B1 (en) * 2015-07-16 2023-10-11 Yeda Research and Development Co., Ltd. Use of anti third party central memory t cells
KR20180063320A (ko) * 2015-10-20 2018-06-11 카이트 파마 인코포레이티드 T 세포 요법을 위한 t 세포를 제조하는 방법
MX2019007963A (es) * 2017-01-06 2019-10-21 Iovance Biotherapeutics Inc Expansion de linfocitos infiltrantes de tumor (til) con agonistas de la superfamilia de recptor de factor de necrosis tumoral (tnfrsf) y combinaciones terapeuticas de til- y agonistas de tnfrsf.
KR20200003913A (ko) * 2017-05-10 2020-01-10 이오반스 바이오테라퓨틱스, 인크. 액상 종양으로부터의 종양 침윤 림프구의 확장 및 그의 치료 용도
CR20200251A (es) * 2017-11-17 2020-07-17 Iovance Biotherapeutics Inc Expansión de til de aspirados con aguja fina y biopsias por punción
US20190284553A1 (en) * 2018-03-15 2019-09-19 KSQ Therapeutics, Inc. Gene-regulating compositions and methods for improved immunotherapy

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