CN116096865A - 用于激活和扩增肿瘤浸润淋巴细胞的方法 - Google Patents

用于激活和扩增肿瘤浸润淋巴细胞的方法 Download PDF

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CN116096865A
CN116096865A CN202180031516.0A CN202180031516A CN116096865A CN 116096865 A CN116096865 A CN 116096865A CN 202180031516 A CN202180031516 A CN 202180031516A CN 116096865 A CN116096865 A CN 116096865A
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til
population
cytokine
culture medium
final concentration
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迈卡·本森
诺亚·雅各布·图博
尼古拉斯·约翰·克莱蒂
罗伯特·安德鲁·拉莫特
格雷戈里·V·克留科夫
迈克尔·施拉巴赫
肖恩·菲利普·利里·阿劳卡斯
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Ksq Treatment Co
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CN202180031516.0A 2020-02-28 2021-02-26 用于激活和扩增肿瘤浸润淋巴细胞的方法 Pending CN116096865A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202062983416P 2020-02-28 2020-02-28
US62/983,416 2020-02-28
US202063074841P 2020-09-04 2020-09-04
US63/074,841 2020-09-04
US202163144853P 2021-02-02 2021-02-02
US63/144,853 2021-02-02
PCT/US2021/019861 WO2021173964A1 (en) 2020-02-28 2021-02-26 Methods for activation and expansion of tumor infiltrating lymphocytes

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CN116096865A true CN116096865A (zh) 2023-05-09

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US (1) US20230108584A1 (https=)
EP (1) EP4110352A4 (https=)
JP (1) JP2023516300A (https=)
KR (1) KR20230034198A (https=)
CN (1) CN116096865A (https=)
AU (1) AU2021228701A1 (https=)
CA (1) CA3168932A1 (https=)
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WO2025055493A1 (zh) * 2023-09-15 2025-03-20 毕诺济(上海)生物技术有限公司 基因编辑的肿瘤浸润淋巴细胞及其在免疫细胞治疗中的应用
WO2025092690A1 (zh) * 2023-10-30 2025-05-08 苏州沙砾生物科技有限公司 一种修饰的细胞及其用途

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CN109536444B (zh) * 2018-12-11 2022-06-28 吉林省拓华生物科技有限公司 一种适用于恶性实体瘤肿瘤浸润t淋巴细胞的分离诱导方法
US12365871B2 (en) 2020-04-28 2025-07-22 Lyell Immunopharma, Inc. Methods for culturing cells
CN114901805B (zh) 2020-11-19 2023-07-25 苏州沙砾生物科技有限公司 肿瘤浸润淋巴细胞的培养方法及其用途
AU2022227686A1 (en) 2021-02-25 2023-07-27 Lyell Immunopharma, Inc. Ror1 targeting chimeric antigen receptor
US20240197873A1 (en) * 2021-04-23 2024-06-20 Suzhou Grit Biotechnology Co., Ltd. Modified tumor-infiltrating lymphocyte and use thereof
AU2022409848A1 (en) * 2021-12-17 2024-07-04 Instil Bio, Inc. Processing of tumor infiltrating lymphocytes
CN118414422A (zh) * 2021-12-30 2024-07-30 苏州沙砾生物科技有限公司 一种修饰的肿瘤浸润淋巴细胞及其用途
EP4471128A4 (en) * 2022-01-29 2026-03-04 Suzhou Grit Biotechnology Co Ltd Modified tumor infiltrating lymphocyte and use thereof
WO2024020531A1 (en) * 2022-07-21 2024-01-25 Tract Therapeutics, Inc. Immune cell expansion and uses thereof
WO2024215414A1 (en) * 2023-04-12 2024-10-17 Beam Therapeutics Inc. Modified immune effector cells with improved efficacy
WO2025096638A2 (en) * 2023-10-30 2025-05-08 Turnstone Biologics Corp. Genetically modified tumor infilitrating lymphocytes and methods of producing and using the same
WO2025106513A1 (en) * 2023-11-13 2025-05-22 KSQ Therapeutics, Inc. Methods for producing edited tumor infiltrating lymphocytes

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WO2025055493A1 (zh) * 2023-09-15 2025-03-20 毕诺济(上海)生物技术有限公司 基因编辑的肿瘤浸润淋巴细胞及其在免疫细胞治疗中的应用
WO2025092690A1 (zh) * 2023-10-30 2025-05-08 苏州沙砾生物科技有限公司 一种修饰的细胞及其用途

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US20230108584A1 (en) 2023-04-06
AU2021228701A1 (en) 2022-09-15
CA3168932A1 (en) 2021-09-02
EP4110352A1 (en) 2023-01-04
JP2023516300A (ja) 2023-04-19

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