JP2023514750A5 - - Google Patents
Info
- Publication number
- JP2023514750A5 JP2023514750A5 JP2022550891A JP2022550891A JP2023514750A5 JP 2023514750 A5 JP2023514750 A5 JP 2023514750A5 JP 2022550891 A JP2022550891 A JP 2022550891A JP 2022550891 A JP2022550891 A JP 2022550891A JP 2023514750 A5 JP2023514750 A5 JP 2023514750A5
- Authority
- JP
- Japan
- Prior art keywords
- cycloalkyl
- groups
- heterocycloalkyl
- group
- optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062980700P | 2020-02-24 | 2020-02-24 | |
| US62/980,700 | 2020-02-24 | ||
| US202063053565P | 2020-07-17 | 2020-07-17 | |
| US63/053,565 | 2020-07-17 | ||
| PCT/US2021/019181 WO2021173523A1 (en) | 2020-02-24 | 2021-02-23 | Hot melt extruded solid dispersions containing a bcl2 inhibitor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023514750A JP2023514750A (ja) | 2023-04-07 |
| JP2023514750A5 true JP2023514750A5 (https=) | 2024-03-04 |
| JP7849296B2 JP7849296B2 (ja) | 2026-04-21 |
Family
ID=74875347
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022550891A Active JP7849296B2 (ja) | 2020-02-24 | 2021-02-23 | Ｂｃｌ２阻害剤を含むホットメルト押出し固体分散体 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230295183A1 (https=) |
| EP (1) | EP4110298A1 (https=) |
| JP (1) | JP7849296B2 (https=) |
| KR (1) | KR20220158725A (https=) |
| CN (1) | CN115484933B (https=) |
| AU (1) | AU2021228622A1 (https=) |
| CA (1) | CA3173041A1 (https=) |
| IL (1) | IL295803A (https=) |
| MX (1) | MX2022010410A (https=) |
| WO (1) | WO2021173523A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3238433A1 (en) | 2021-12-06 | 2023-06-15 | Xingguo LIU | Anti-apoptotic protein bcl-2 inhibitor, pharmaceutical composition and uses thereof |
| TW202340210A (zh) | 2022-01-21 | 2023-10-16 | 美商艾伯維有限公司 | １，３，４，７－四氫－２Ｈ－吡咯并［３＇，２＇：５，６］吡啶并［２，３－ｂ］［１，４］氮呯Ｂｃｌ－２抑制劑 |
| CN115894495B (zh) * | 2022-11-29 | 2024-08-09 | 大连理工大学 | 一种基于尿酸与苯硼酸衍生物复合晶体的纯有机室温磷光材料的制备方法 |
| CN116270660A (zh) * | 2023-03-30 | 2023-06-23 | 广州麓鹏制药有限公司 | 一种含Bcl-2/Bcl-xl抑制剂的组合物及其制备方法与应用 |
| CN116236583A (zh) * | 2023-03-30 | 2023-06-09 | 广州麓鹏制药有限公司 | 一种含Bcl-2/Bcl-xl抑制剂的组合物及其制备方法与应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19913692A1 (de) | 1999-03-25 | 2000-09-28 | Basf Ag | Mechanisch stabile pharmazeutische Darreichungsformen, enthaltend flüssige oder halbfeste oberflächenaktive Substanzen |
| DE19929361A1 (de) | 1999-06-25 | 2001-01-04 | Basf Ag | Mechanisch stabile pharmazeutische Darreichungsformen, enthaltend flüssige oder halbfeste oberflächenaktive Substanzen |
| WO2005049593A2 (en) | 2003-11-13 | 2005-06-02 | Abbott Laboratories | N-acylsulfonamide apoptosis promoters |
| US7790190B2 (en) | 2004-03-20 | 2010-09-07 | Yasoo Health, Inc. | Aqueous emulsions of lipophile solubilized with vitamin E TPGS and linoleic acid |
| US20080182845A1 (en) | 2006-11-16 | 2008-07-31 | Abbott Laboratories | Method of preventing or treating organ, hematopoietic stem cell or bone marrow transplant rejection |
| CA2705294C (en) | 2007-11-16 | 2016-05-17 | Abbott Laboratories | Methods of treating arthritis by the administration of substituted benzenesulfonamides |
| US20100297194A1 (en) * | 2009-04-30 | 2010-11-25 | Nathaniel Catron | Formulation for oral administration of apoptosis promoter |
| TWI471321B (zh) * | 2009-06-08 | 2015-02-01 | 亞培公司 | Ｂｃｌ－２族群抑制劑之口服醫藥劑型 |
| CA3152557A1 (en) * | 2010-10-29 | 2012-05-03 | Abbvie Inc. | Solid dispersions containing an apoptosis-inducing agent |
| UA113500C2 (xx) * | 2010-10-29 | 2017-02-10 | Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб | |
| CN106232144B (zh) * | 2014-03-18 | 2019-12-06 | 武田药品工业株式会社 | 固体分散体 |
| WO2017132474A1 (en) | 2016-01-30 | 2017-08-03 | Newave Pharmaceutical Inc. | Bcl-2 inhibitors |
| EP3333167A1 (en) * | 2016-12-09 | 2018-06-13 | LEK Pharmaceuticals d.d. | Solid forms of venetoclax |
| CN111511748B (zh) * | 2017-08-23 | 2023-05-02 | 广州麓鹏制药有限公司 | Bcl-2抑制剂 |
| US11903950B2 (en) * | 2018-08-22 | 2024-02-20 | Newave Pharmaceutical Inc. | BCL-2 inhibitors |
-
2021
- 2021-02-23 JP JP2022550891A patent/JP7849296B2/ja active Active
- 2021-02-23 CN CN202180016511.0A patent/CN115484933B/zh active Active
- 2021-02-23 WO PCT/US2021/019181 patent/WO2021173523A1/en not_active Ceased
- 2021-02-23 CA CA3173041A patent/CA3173041A1/en active Pending
- 2021-02-23 KR KR1020227033262A patent/KR20220158725A/ko active Pending
- 2021-02-23 MX MX2022010410A patent/MX2022010410A/es unknown
- 2021-02-23 EP EP21712350.4A patent/EP4110298A1/en active Pending
- 2021-02-23 US US17/798,904 patent/US20230295183A1/en active Pending
- 2021-02-23 IL IL295803A patent/IL295803A/en unknown
- 2021-02-23 AU AU2021228622A patent/AU2021228622A1/en active Pending
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