JP2023512452A5 - - Google Patents
Info
- Publication number
- JP2023512452A5 JP2023512452A5 JP2022542664A JP2022542664A JP2023512452A5 JP 2023512452 A5 JP2023512452 A5 JP 2023512452A5 JP 2022542664 A JP2022542664 A JP 2022542664A JP 2022542664 A JP2022542664 A JP 2022542664A JP 2023512452 A5 JP2023512452 A5 JP 2023512452A5
- Authority
- JP
- Japan
- Prior art keywords
- bcma
- cells
- subdomain
- intracellular signaling
- car
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062960285P | 2020-01-13 | 2020-01-13 | |
| US62/960,285 | 2020-01-13 | ||
| PCT/US2021/012977 WO2021146147A1 (en) | 2020-01-13 | 2021-01-11 | Bcma-directed cellular immunotherapy compositions and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023512452A JP2023512452A (ja) | 2023-03-27 |
| JP2023512452A5 true JP2023512452A5 (enExample) | 2024-01-18 |
Family
ID=76864781
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022542664A Pending JP2023512452A (ja) | 2020-01-13 | 2021-01-11 | Ｂｃｍａ指向性細胞免疫療法組成物および方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230028399A1 (enExample) |
| EP (1) | EP4090337A4 (enExample) |
| JP (1) | JP2023512452A (enExample) |
| KR (1) | KR20220128650A (enExample) |
| CN (1) | CN115279381A (enExample) |
| AU (1) | AU2021207795A1 (enExample) |
| CA (1) | CA3164666A1 (enExample) |
| IL (1) | IL294518A (enExample) |
| MX (1) | MX2022008638A (enExample) |
| WO (1) | WO2021146147A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3805371A1 (en) | 2014-05-15 | 2021-04-14 | National University of Singapore | Modified natural killer cells and uses thereof |
| CN117363636A (zh) | 2017-03-27 | 2024-01-09 | 新加坡国立大学 | 一种编码嵌合受体的多核苷酸 |
| JP7360174B2 (ja) | 2018-02-09 | 2023-10-12 | ナショナル ユニヴァーシティー オブ シンガポール | ナチュラルキラー細胞免疫療法における活性化キメラ受容体及びその使用 |
| US12441787B2 (en) | 2018-04-02 | 2025-10-14 | National University Of Singapore | Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells |
| WO2020044239A1 (en) | 2018-08-29 | 2020-03-05 | National University Of Singapore | A method to specifically stimulate survival and expansion of genetically-modified immune cells |
| KR20210137085A (ko) | 2019-03-05 | 2021-11-17 | 엔카르타, 인크. | Cd19 유도된 키메라 항원 수용체 및 면역 요법에서 이의 용도 |
| CA3241912A1 (en) * | 2021-12-07 | 2023-06-15 | Huafeng Wei | Antibody binding to bcma and use thereof |
| WO2025171388A1 (en) | 2024-02-09 | 2025-08-14 | Dispatch Biotherapeutics, Inc. | Engineered cancer antigens with modified domains and related methods and uses |
| WO2025171383A2 (en) | 2024-02-09 | 2025-08-14 | Dispatch Biotherapeutics, Inc. | Engineered cancer antigens and related methods and uses |
| WO2026006767A1 (en) | 2024-06-28 | 2026-01-02 | Dispatch Biotherapeutics, Inc. | Tethered il-9/il-9r and related engineered cells and methods |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060057680A1 (en) * | 2004-08-11 | 2006-03-16 | Zheng Xin X | Mutant interleukin-15 polypeptides |
| AU2013246443B2 (en) * | 2012-04-11 | 2017-04-27 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Chimeric antigen receptors targeting B-cell maturation antigen |
| IL305629A (en) * | 2013-02-15 | 2023-11-01 | Univ California | Chimeric antigen receptor and methods of using it |
| AU2015292744C1 (en) * | 2014-07-21 | 2021-01-21 | Novartis Ag | Treatment of cancer using humanized anti-BCMA chimeric antigen receptor |
| GB201503742D0 (en) * | 2015-03-05 | 2015-04-22 | Ucl Business Plc | Chimeric antigen receptor |
| TWI833684B (zh) * | 2015-06-25 | 2024-03-01 | 美商生物細胞基因治療有限公司 | 嵌合抗原受體（ｃａｒ）、組合物及其使用方法 |
| CN117363636A (zh) * | 2017-03-27 | 2024-01-09 | 新加坡国立大学 | 一种编码嵌合受体的多核苷酸 |
| ES3052818T3 (en) * | 2018-02-09 | 2026-01-14 | Us Health | Tethered interleukin-15 and interleukin-21 |
| IL279367B2 (en) * | 2018-06-13 | 2026-05-01 | Novartis Ag | BCMA chimeric antigen receptors and their uses |
| CN109320615B (zh) * | 2018-09-25 | 2023-09-22 | 上海恒润达生生物科技股份有限公司 | 靶向新型bcma的嵌合抗原受体及其用途 |
| KR20210137085A (ko) * | 2019-03-05 | 2021-11-17 | 엔카르타, 인크. | Cd19 유도된 키메라 항원 수용체 및 면역 요법에서 이의 용도 |
| CN114174325A (zh) * | 2019-06-04 | 2022-03-11 | 恩卡尔塔公司 | 用于免疫疗法的工程化自然杀伤细胞和工程化t细胞的组合 |
-
2021
- 2021-01-11 WO PCT/US2021/012977 patent/WO2021146147A1/en not_active Ceased
- 2021-01-11 CA CA3164666A patent/CA3164666A1/en active Pending
- 2021-01-11 US US17/758,116 patent/US20230028399A1/en not_active Abandoned
- 2021-01-11 MX MX2022008638A patent/MX2022008638A/es unknown
- 2021-01-11 EP EP21740869.9A patent/EP4090337A4/en active Pending
- 2021-01-11 KR KR1020227028061A patent/KR20220128650A/ko active Pending
- 2021-01-11 IL IL294518A patent/IL294518A/en unknown
- 2021-01-11 JP JP2022542664A patent/JP2023512452A/ja active Pending
- 2021-01-11 AU AU2021207795A patent/AU2021207795A1/en active Pending
- 2021-01-11 CN CN202180019394.3A patent/CN115279381A/zh active Pending