KR20220128650A - Bcma-유도된 세포 면역요법 조성물 및 방법 - Google Patents

Bcma-유도된 세포 면역요법 조성물 및 방법 Download PDF

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KR20220128650A
KR20220128650A KR1020227028061A KR20227028061A KR20220128650A KR 20220128650 A KR20220128650 A KR 20220128650A KR 1020227028061 A KR1020227028061 A KR 1020227028061A KR 20227028061 A KR20227028061 A KR 20227028061A KR 20220128650 A KR20220128650 A KR 20220128650A
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seq
bcma
domain
chimeric antigen
antigen receptor
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Korean (ko)
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카냐 락쉬미 라잔감
제임스 바나비 트레이거
루쑤안 구오 버렌
차오 구오
알렉산드라 레이다 리아나 라제틱
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엔카르타, 인크.
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    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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KR1020227028061A 2020-01-13 2021-01-11 Bcma-유도된 세포 면역요법 조성물 및 방법 Pending KR20220128650A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062960285P 2020-01-13 2020-01-13
US62/960,285 2020-01-13
PCT/US2021/012977 WO2021146147A1 (en) 2020-01-13 2021-01-11 Bcma-directed cellular immunotherapy compositions and methods

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KR20220128650A true KR20220128650A (ko) 2022-09-21

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US (1) US20230028399A1 (enExample)
EP (1) EP4090337A4 (enExample)
JP (1) JP2023512452A (enExample)
KR (1) KR20220128650A (enExample)
CN (1) CN115279381A (enExample)
AU (1) AU2021207795A1 (enExample)
CA (1) CA3164666A1 (enExample)
IL (1) IL294518A (enExample)
MX (1) MX2022008638A (enExample)
WO (1) WO2021146147A1 (enExample)

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EP3805371A1 (en) 2014-05-15 2021-04-14 National University of Singapore Modified natural killer cells and uses thereof
CN117363636A (zh) 2017-03-27 2024-01-09 新加坡国立大学 一种编码嵌合受体的多核苷酸
JP7360174B2 (ja) 2018-02-09 2023-10-12 ナショナル ユニヴァーシティー オブ シンガポール ナチュラルキラー細胞免疫療法における活性化キメラ受容体及びその使用
US12441787B2 (en) 2018-04-02 2025-10-14 National University Of Singapore Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells
WO2020044239A1 (en) 2018-08-29 2020-03-05 National University Of Singapore A method to specifically stimulate survival and expansion of genetically-modified immune cells
KR20210137085A (ko) 2019-03-05 2021-11-17 엔카르타, 인크. Cd19 유도된 키메라 항원 수용체 및 면역 요법에서 이의 용도
CA3241912A1 (en) * 2021-12-07 2023-06-15 Huafeng Wei Antibody binding to bcma and use thereof
WO2025171388A1 (en) 2024-02-09 2025-08-14 Dispatch Biotherapeutics, Inc. Engineered cancer antigens with modified domains and related methods and uses
WO2025171383A2 (en) 2024-02-09 2025-08-14 Dispatch Biotherapeutics, Inc. Engineered cancer antigens and related methods and uses
WO2026006767A1 (en) 2024-06-28 2026-01-02 Dispatch Biotherapeutics, Inc. Tethered il-9/il-9r and related engineered cells and methods

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US20060057680A1 (en) * 2004-08-11 2006-03-16 Zheng Xin X Mutant interleukin-15 polypeptides
AU2013246443B2 (en) * 2012-04-11 2017-04-27 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Chimeric antigen receptors targeting B-cell maturation antigen
IL305629A (en) * 2013-02-15 2023-11-01 Univ California Chimeric antigen receptor and methods of using it
AU2015292744C1 (en) * 2014-07-21 2021-01-21 Novartis Ag Treatment of cancer using humanized anti-BCMA chimeric antigen receptor
GB201503742D0 (en) * 2015-03-05 2015-04-22 Ucl Business Plc Chimeric antigen receptor
TWI833684B (zh) * 2015-06-25 2024-03-01 美商生物細胞基因治療有限公司 嵌合抗原受體（ｃａｒ）、組合物及其使用方法
CN117363636A (zh) * 2017-03-27 2024-01-09 新加坡国立大学 一种编码嵌合受体的多核苷酸
ES3052818T3 (en) * 2018-02-09 2026-01-14 Us Health Tethered interleukin-15 and interleukin-21
IL279367B2 (en) * 2018-06-13 2026-05-01 Novartis Ag BCMA chimeric antigen receptors and their uses
CN109320615B (zh) * 2018-09-25 2023-09-22 上海恒润达生生物科技股份有限公司 靶向新型bcma的嵌合抗原受体及其用途
KR20210137085A (ko) * 2019-03-05 2021-11-17 엔카르타, 인크. Cd19 유도된 키메라 항원 수용체 및 면역 요법에서 이의 용도
CN114174325A (zh) * 2019-06-04 2022-03-11 恩卡尔塔公司 用于免疫疗法的工程化自然杀伤细胞和工程化t细胞的组合

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AU2021207795A1 (en) 2022-07-28
MX2022008638A (es) 2022-08-08
JP2023512452A (ja) 2023-03-27
EP4090337A1 (en) 2022-11-23
CN115279381A (zh) 2022-11-01
WO2021146147A1 (en) 2021-07-22
US20230028399A1 (en) 2023-01-26
EP4090337A4 (en) 2024-04-24
IL294518A (en) 2022-09-01

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