JP2023511908A5 - - Google Patents

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Publication number
JP2023511908A5
JP2023511908A5 JP2022544353A JP2022544353A JP2023511908A5 JP 2023511908 A5 JP2023511908 A5 JP 2023511908A5 JP 2022544353 A JP2022544353 A JP 2022544353A JP 2022544353 A JP2022544353 A JP 2022544353A JP 2023511908 A5 JP2023511908 A5 JP 2023511908A5
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JP
Japan
Application number
JP2022544353A
Other languages
Japanese (ja)
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JP2023511908A (ja
JPWO2021151012A5 (https=
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/014780 external-priority patent/WO2021151012A1/en
Publication of JP2023511908A publication Critical patent/JP2023511908A/ja
Publication of JPWO2021151012A5 publication Critical patent/JPWO2021151012A5/ja
Publication of JP2023511908A5 publication Critical patent/JP2023511908A5/ja
Pending legal-status Critical Current

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JP2022544353A 2020-01-22 2021-01-22 タウ発現抑制のためのジンクフィンガータンパク質転写因子 Pending JP2023511908A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062964501P 2020-01-22 2020-01-22
US62/964,501 2020-01-22
PCT/US2021/014780 WO2021151012A1 (en) 2020-01-22 2021-01-22 Zinc finger protein transcription factors for repressing tau expression

Publications (3)

Publication Number Publication Date
JP2023511908A JP2023511908A (ja) 2023-03-23
JPWO2021151012A5 JPWO2021151012A5 (https=) 2024-02-09
JP2023511908A5 true JP2023511908A5 (https=) 2024-02-09

Family

ID=74661487

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022544353A Pending JP2023511908A (ja) 2020-01-22 2021-01-22 タウ発現抑制のためのジンクフィンガータンパク質転写因子

Country Status (14)

Country Link
US (1) US20230242602A1 (https=)
EP (1) EP4093754A1 (https=)
JP (1) JP2023511908A (https=)
KR (1) KR20220131273A (https=)
CN (1) CN115210251A (https=)
AR (1) AR121118A1 (https=)
AU (1) AU2021209699A1 (https=)
BR (1) BR112022014160A2 (https=)
CA (1) CA3168805A1 (https=)
IL (1) IL294535A (https=)
MX (1) MX2022008953A (https=)
TW (1) TW202134288A (https=)
UY (1) UY39036A (https=)
WO (1) WO2021151012A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110214184B (zh) 2016-12-01 2024-07-02 桑格摩生物治疗股份有限公司 τ蛋白调节剂以及用于其递送的方法和组合物
KR20210070344A (ko) 2018-10-02 2021-06-14 상가모 테라퓨틱스, 인코포레이티드 타우 단백질의 조정을 위한 방법 및 조성물
KR20220071248A (ko) * 2019-10-02 2022-05-31 상가모 테라퓨틱스, 인코포레이티드 알파-시누클레인 발현을 억제시키기 위한 아연 핑거 단백질 전사 인자
WO2025193848A1 (en) * 2024-03-13 2025-09-18 Sangamo Therapeutics, Inc. Delivery of tau repressors using the blood-brain barrier penetrant capsid

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69534629D1 (de) 1994-01-18 2005-12-29 Scripps Research Inst Derivate von zinkfingerproteinen und methoden
US6140466A (en) 1994-01-18 2000-10-31 The Scripps Research Institute Zinc finger protein derivatives and methods therefor
ATE524545T1 (de) 1994-08-20 2011-09-15 Gendaq Ltd Verbesserungen bei oder im zusammenhang mit bindeproteinen zur erkennung von dna
GB9824544D0 (en) 1998-11-09 1999-01-06 Medical Res Council Screening system
GB9710807D0 (en) 1997-05-23 1997-07-23 Medical Res Council Nucleic acid binding proteins
GB9710809D0 (en) 1997-05-23 1997-07-23 Medical Res Council Nucleic acid binding proteins
DE69942334D1 (de) 1998-03-02 2010-06-17 Massachusetts Inst Technology Poly-zinkfinger-proteine mit verbesserten linkern
WO2001053480A1 (en) 2000-01-24 2001-07-26 Sangamo Biosciences, Inc. Nucleic acid binding polypeptides characterized by flexible linkers connected nucleic acid binding modules
US20020061512A1 (en) 2000-02-18 2002-05-23 Kim Jin-Soo Zinc finger domains and methods of identifying same
US20030044787A1 (en) 2000-05-16 2003-03-06 Joung J. Keith Methods and compositions for interaction trap assays
JP2002060786A (ja) 2000-08-23 2002-02-26 Kao Corp 硬質表面用殺菌防汚剤
GB0108491D0 (en) 2001-04-04 2001-05-23 Gendaq Ltd Engineering zinc fingers
US20040224385A1 (en) 2001-08-20 2004-11-11 Barbas Carlos F Zinc finger binding domains for cnn
US9394531B2 (en) 2008-05-28 2016-07-19 Sangamo Biosciences, Inc. Compositions for linking DNA-binding domains and cleavage domains
PT2566972T (pt) 2010-05-03 2020-03-02 Sangamo Biosciences Inc Composições para a ligação de módulos de dedo de zinco
AU2014312295C1 (en) 2013-08-28 2020-08-13 Sangamo Therapeutics, Inc. Compositions for linking DNA-binding domains and cleavage domains
CN106459894B (zh) 2014-03-18 2020-02-18 桑格摩生物科学股份有限公司 用于调控锌指蛋白表达的方法和组合物
WO2017011556A1 (en) * 2015-07-13 2017-01-19 The General Hospital Corporation Rare phosphorylated high molecular weight (hmw) tau species that are involved in neuronal uptake and propagation and applications thereof
EP3411056A4 (en) 2016-02-02 2019-10-02 Sangamo Therapeutics, Inc. COMPOUNDS FOR NETWORKING DNA BINDING DOMAINS AND SPLITTING DOMAINS
SG10201913948PA (en) 2016-08-24 2020-03-30 Sangamo Therapeutics Inc Engineered target specific nucleases
CN110214184B (zh) * 2016-12-01 2024-07-02 桑格摩生物治疗股份有限公司 τ蛋白调节剂以及用于其递送的方法和组合物
CA3115158A1 (en) 2018-10-02 2020-04-09 Sangamo Therapeutics, Inc. Engineered genetic modulators
KR20210070344A (ko) 2018-10-02 2021-06-14 상가모 테라퓨틱스, 인코포레이티드 타우 단백질의 조정을 위한 방법 및 조성물

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