JP2023511898A5 - - Google Patents

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Publication number
JP2023511898A5
JP2023511898A5 JP2022544267A JP2022544267A JP2023511898A5 JP 2023511898 A5 JP2023511898 A5 JP 2023511898A5 JP 2022544267 A JP2022544267 A JP 2022544267A JP 2022544267 A JP2022544267 A JP 2022544267A JP 2023511898 A5 JP2023511898 A5 JP 2023511898A5
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JP
Japan
Prior art keywords
antigen
bispecific antibody
binding moiety
seq
binding portion
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JP2022544267A
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English (en)
Japanese (ja)
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JP2023511898A (ja
JP7692422B2 (ja
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Priority claimed from PCT/CN2021/072584 external-priority patent/WO2021147829A1/en
Publication of JP2023511898A publication Critical patent/JP2023511898A/ja
Publication of JP2023511898A5 publication Critical patent/JP2023511898A5/ja
Application granted granted Critical
Publication of JP7692422B2 publication Critical patent/JP7692422B2/ja
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JP2022544267A 2020-01-21 2021-01-19 二重特異性抗pd-l1/vegf抗体及びその使用 Active JP7692422B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2020073497 2020-01-21
CNPCT/CN2020/073497 2020-01-21
PCT/CN2021/072584 WO2021147829A1 (en) 2020-01-21 2021-01-19 A bispecific anti-pd-l1/vegf antibody and uses thereof

Publications (3)

Publication Number Publication Date
JP2023511898A JP2023511898A (ja) 2023-03-23
JP2023511898A5 true JP2023511898A5 (https=) 2024-01-09
JP7692422B2 JP7692422B2 (ja) 2025-06-13

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ID=76993149

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JP2022544267A Active JP7692422B2 (ja) 2020-01-21 2021-01-19 二重特異性抗pd-l1/vegf抗体及びその使用

Country Status (8)

Country Link
US (1) US20230242645A1 (https=)
EP (1) EP4093765A4 (https=)
JP (1) JP7692422B2 (https=)
AU (1) AU2021210025A1 (https=)
BR (1) BR112022014487A2 (https=)
CA (1) CA3165556A1 (https=)
WO (1) WO2021147829A1 (https=)
ZA (1) ZA202208337B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114106190B (zh) * 2020-08-31 2025-04-08 普米斯生物技术(珠海)有限公司 一种抗vegf/pd-l1双特异性抗体及其用途
CN114230669B (zh) * 2021-12-24 2024-01-30 天士力生物医药股份有限公司 一种双特异性抗体的生产方法
EP4543488A2 (en) * 2022-08-25 2025-04-30 Bright Biologics LLC Multispecific antibodies and uses thereof
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof
WO2025257394A1 (en) * 2024-06-14 2025-12-18 BioNTech SE Combination therapy for cancer treatment
WO2025256761A1 (en) * 2024-06-14 2025-12-18 BioNTech SE Combination therapy for cancer treatment

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6884879B1 (en) * 1997-04-07 2005-04-26 Genentech, Inc. Anti-VEGF antibodies
CN106397592A (zh) * 2015-07-31 2017-02-15 苏州康宁杰瑞生物科技有限公司 针对程序性死亡配体(pd-l1)的单域抗体及其衍生蛋白
CN109575140B (zh) * 2017-09-29 2021-02-23 北京比洋生物技术有限公司 靶向pd-1或pd-l1且靶向vegf家族的双靶向融合蛋白及其用途
CA3090878A1 (en) * 2018-02-11 2019-08-15 Beijing Hanmi Pharmaceutical Co., Ltd. Anti-pd-1/anti-vegf natural antibody structure-like heterodimeric form bispecific antibody and preparation thereof
EP3758735B1 (en) * 2018-02-28 2023-12-13 AP Biosciences, Inc. Bifunctional proteins combining checkpoint blockade for targeted therapy
CN110305210B (zh) * 2018-03-27 2023-02-28 信达生物制药(苏州)有限公司 新型抗体分子、其制备方法及其用途
WO2019184909A1 (zh) * 2018-03-27 2019-10-03 信达生物制药(苏州)有限公司 新型抗体分子、其制备方法及其用途
CN109053895B (zh) 2018-08-30 2020-06-09 中山康方生物医药有限公司 抗pd-1-抗vegfa的双功能抗体、其药物组合物及其用途
CN109942712B (zh) * 2019-04-01 2022-12-20 华博生物医药技术(上海)有限公司 抗pd-l1/vegf双功能抗体及其用途
WO2021057836A1 (en) 2019-09-25 2021-04-01 Wuxi Biologics (Shanghai) Co. Ltd. Novel anti-pd-l1 antibodies

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