JP2023510590A5 - - Google Patents

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Publication number
JP2023510590A5
JP2023510590A5 JP2022543381A JP2022543381A JP2023510590A5 JP 2023510590 A5 JP2023510590 A5 JP 2023510590A5 JP 2022543381 A JP2022543381 A JP 2022543381A JP 2022543381 A JP2022543381 A JP 2022543381A JP 2023510590 A5 JP2023510590 A5 JP 2023510590A5
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JP
Japan
Prior art keywords
cell line
raav
weight
nucleic acid
transfected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022543381A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023510590A (ja
JP7846625B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/013689 external-priority patent/WO2021146591A2/en
Publication of JP2023510590A publication Critical patent/JP2023510590A/ja
Publication of JP2023510590A5 publication Critical patent/JP2023510590A5/ja
Priority to JP2025195186A priority Critical patent/JP2026032042A/ja
Application granted granted Critical
Publication of JP7846625B2 publication Critical patent/JP7846625B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2022543381A 2020-01-17 2021-01-15 組換えａａｖの産生 Active JP7846625B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025195186A JP2026032042A (ja) 2020-01-17 2025-11-14 組換えａａｖの産生

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062962911P 2020-01-17 2020-01-17
US62/962,911 2020-01-17
PCT/US2021/013689 WO2021146591A2 (en) 2020-01-17 2021-01-15 Recombinant aav production

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025195186A Division JP2026032042A (ja) 2020-01-17 2025-11-14 組換えａａｖの産生

Publications (3)

Publication Number Publication Date
JP2023510590A JP2023510590A (ja) 2023-03-14
JP2023510590A5 true JP2023510590A5 (https=) 2024-01-23
JP7846625B2 JP7846625B2 (ja) 2026-04-15

Family

ID=76864730

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022543381A Active JP7846625B2 (ja) 2020-01-17 2021-01-15 組換えａａｖの産生
JP2025195186A Pending JP2026032042A (ja) 2020-01-17 2025-11-14 組換えａａｖの産生

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025195186A Pending JP2026032042A (ja) 2020-01-17 2025-11-14 組換えａａｖの産生

Country Status (8)

Country Link
US (1) US20230048994A1 (https=)
EP (1) EP4090750A4 (https=)
JP (2) JP7846625B2 (https=)
CN (1) CN115315518A (https=)
AU (1) AU2021207683A1 (https=)
CA (1) CA3162520A1 (https=)
IL (1) IL294775A (https=)
WO (1) WO2021146591A2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12054738B2 (en) 2020-07-30 2024-08-06 Shape Therapeutics Inc. Stable cell lines for inducible production of rAAV virions
TW202323529A (zh) 2021-10-18 2023-06-16 美商再生元醫藥公司 包括腺病毒相關病毒聚核苷酸的真核細胞
EP4634370A1 (en) * 2022-12-14 2025-10-22 Astellas Gene Therapies, Inc. Compositions and methods for improved production of adeno-associated viral particles
CN120752344A (zh) * 2023-02-17 2025-10-03 新博基股份有限公司 ITR-Rep基因复合体
EP4527938A1 (en) * 2023-09-22 2025-03-26 LenioBio GmbH Method for cell-free polypeptide synthesis

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6989264B2 (en) * 1997-09-05 2006-01-24 Targeted Genetics Corporation Methods for generating high titer helper-free preparations of released recombinant AAV vectors
ES2535877T3 (es) * 2006-06-19 2015-05-18 Asklepios Biopharmaceutical, Inc. Genes de Factor VIII y Factor IX modificados y vectores para la terapia génica
EP2615167A1 (en) * 2006-09-15 2013-07-17 MedImmune, LLC Method for eliminating DNA contaminants from viral preparations
GB0901593D0 (en) * 2009-01-30 2009-03-11 Touchlight Genetics Ltd Production of closed linear DNA
CA2853482C (en) * 2011-10-28 2020-05-19 Joshua Grieger Cell line for production of adeno-associated virus
WO2015031686A1 (en) * 2013-08-30 2015-03-05 Amgen Inc. High titer recombinant aav vector production in adherent and suspension cells
EP3384015A4 (en) * 2015-12-01 2019-05-29 Spark Therapeutics, Inc. SCALABLE PROCESS FOR THE PREPARATION OF A RECOMBINANT ADENO ASSOCIATED VIRAL VECTOR IN A SERUM-FREE SUSPENSION CELL CULTURE SYSTEM SUITABLE FOR THE CLINICAL APPLICATION
EP3810782A2 (en) 2018-06-22 2021-04-28 Asklepios Biopharmaceutical, Inc. Vectors for gene delivery that persist within cells

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