JP2023509964A5 - - Google Patents

Info

Publication number
JP2023509964A5
JP2023509964A5 JP2022542207A JP2022542207A JP2023509964A5 JP 2023509964 A5 JP2023509964 A5 JP 2023509964A5 JP 2022542207 A JP2022542207 A JP 2022542207A JP 2022542207 A JP2022542207 A JP 2022542207A JP 2023509964 A5 JP2023509964 A5 JP 2023509964A5
Authority
JP
Japan
Prior art keywords
producing
eukaryotic
eukaryotically
mrna
ires
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022542207A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023509964A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/012992 external-priority patent/WO2021142458A1/en
Publication of JP2023509964A publication Critical patent/JP2023509964A/ja
Publication of JP2023509964A5 publication Critical patent/JP2023509964A5/ja
Pending legal-status Critical Current

Links

JP2022542207A 2020-01-11 2021-01-11 真核生物翻訳可能mRNAの生成および真核生物への送達のための微生物システム Pending JP2023509964A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202062959976P 2020-01-11 2020-01-11
US62/959,976 2020-01-11
US202063118593P 2020-11-25 2020-11-25
US63/118,593 2020-11-25
PCT/US2021/012992 WO2021142458A1 (en) 2020-01-11 2021-01-11 A microbial system for production and delivery of eukaryote-translatable mrna to eukarya

Publications (2)

Publication Number Publication Date
JP2023509964A JP2023509964A (ja) 2023-03-10
JP2023509964A5 true JP2023509964A5 (https=) 2024-01-18

Family

ID=76788329

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022542207A Pending JP2023509964A (ja) 2020-01-11 2021-01-11 真核生物翻訳可能mRNAの生成および真核生物への送達のための微生物システム

Country Status (8)

Country Link
US (1) US20210222178A1 (https=)
EP (1) EP4087934A4 (https=)
JP (1) JP2023509964A (https=)
KR (1) KR20220150276A (https=)
CN (1) CN115335527A (https=)
AU (1) AU2021206307A1 (https=)
CA (1) CA3164395A1 (https=)
WO (1) WO2021142458A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012019630A1 (en) 2010-08-13 2012-02-16 Curevac Gmbh Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded protein
WO2013120499A1 (en) 2012-02-15 2013-08-22 Curevac Gmbh Nucleic acid comprising or coding for a histone stem-loop and a poly (a) sequence or a polyadenylation signal for increasing the expression of an encoded pathogenic antigen
MX362981B (es) 2012-03-27 2019-02-28 Curevac Ag Moleculas artificiales de acido nucleico para la expresion mejorada de proteina o peptido.
SG10201913630YA (en) 2016-02-17 2020-03-30 Curevac Ag Zika virus vaccine
US12194089B2 (en) 2020-02-04 2025-01-14 CureVac SE Coronavirus vaccine
US11241493B2 (en) 2020-02-04 2022-02-08 Curevac Ag Coronavirus vaccine
IL300447A (en) * 2020-08-12 2023-04-01 Actym Therapeutics Inc Bacteria-based ingredients that stimulate the immune system, treatments and platforms for delivering RNA
US11918643B2 (en) 2020-12-22 2024-03-05 CureVac SE RNA vaccine against SARS-CoV-2 variants
AU2022286964A1 (en) * 2021-06-02 2024-01-18 Sivec Biotechnologies Llc Bacterial delivery of antibodies, antibody derivatives, and polypeptides to eukaryotic cells
CN114507691A (zh) * 2022-03-02 2022-05-17 深圳市瑞吉生物科技有限公司 一种用于制备环状rna的载体及其应用
CN114622020B (zh) * 2022-03-30 2022-09-27 华南农业大学 一种与鸡生长性状相关的klhl31基因分子标记及应用
EP4608442A1 (en) 2022-10-28 2025-09-03 GlaxoSmithKline Biologicals S.A. Nucleic acid based vaccine
CN120400199A (zh) * 2024-01-31 2025-08-01 上海缮维特生物技术有限公司 一种真核表达载体、包含其的细菌及应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1021548A1 (en) * 1997-10-07 2000-07-26 University Of Maryland Biotechnology Institute Method for introducing and expressing rna in animal cells
CN1820020B (zh) * 2003-05-06 2010-04-28 技术持有有限公司 Sars-冠状病毒病毒样颗粒以及应用方法
PL2922554T3 (pl) * 2012-11-26 2022-06-20 Modernatx, Inc. Na zmodyfikowany na końcach
EP2996697B1 (en) * 2013-05-15 2019-06-26 Robert Kruse Intracellular translation of circular rna
EP3607070A4 (en) * 2017-04-03 2020-12-16 Sivec Biotechnologies, LLC TRANS-REIGN PLATFORM FOR THE ADMINISTRATION OF THERAPEUTIC NUCLEIC ACIDS
WO2018185564A2 (en) * 2017-04-07 2018-10-11 Uti Limited Partnership Assay to measure the potency of receptor-ligand interactions in nanomedicines
EP3818163A4 (en) * 2018-07-04 2022-04-06 Pebble Labs USA, Inc. System and methods for engineering bacteria fit for eukaryotic mrna production, export, and translation in a eukaryotic host

Similar Documents

Publication Publication Date Title
JP2023509964A5 (https=)
US20240392304A1 (en) Circular rna and preparation method thereof
JP4321877B2 (ja) トランス―スプライスにより生成される治療用分子
JP2025120176A5 (https=)
TW202136508A (zh) 用於編輯目標rna之附加有功能性領域之反義型嚮導rna
WO2023241669A1 (zh) CRISPR-Cas效应子蛋白、其基因编辑系统及应用
JP2001136966A (ja) 改良組換dna分子
JP2020510426A5 (https=)
JP2004501646A5 (https=)
CN118222588B (zh) 一种减毒型弓形虫疫苗株及其制备方法和在抗肿瘤中的应用
JP2024539089A5 (https=)
CN113774085A (zh) 一种单碱基编辑工具TaC9-ABE及其应用
WO2025102994A1 (zh) 基于i型内含子的rna体外环化与滚环翻译的方法及其应用
CN119855906A (zh) 包含改善mRNA细胞内稳定性和生物合成的UTR序列的构建体及其用途
JP2006502691A (ja) 発現系
WO2024083095A1 (zh) 环状rna及载体和载体的应用
JP2023521149A5 (https=)
CN118652889B (zh) 一种环状核酶系统及其应用
CN111051509A (zh) 用于电介质校准的含有c2cl核酸内切酶的组合物以及使用其进行电介质校准的方法
CN110577969B (zh) CRISPR/Sa-SlugCas9基因编辑系统及其应用
CN111718964A (zh) 用于修复dmd基因突变的核酸序列及系统
Licis et al. Forced retroevolution of an RNA bacteriophage
CN116286738B (zh) Dsb-pe基因编辑系统及其应用
TW202503054A (zh) 環形rna及其製備方法
JP2025503476A5 (https=)