JP2023507729A5 - - Google Patents
Info
- Publication number
- JP2023507729A5 JP2023507729A5 JP2022536937A JP2022536937A JP2023507729A5 JP 2023507729 A5 JP2023507729 A5 JP 2023507729A5 JP 2022536937 A JP2022536937 A JP 2022536937A JP 2022536937 A JP2022536937 A JP 2022536937A JP 2023507729 A5 JP2023507729 A5 JP 2023507729A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- cancer
- molecule according
- antigen
- binding domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962949220P | 2019-12-17 | 2019-12-17 | |
| US62/949,220 | 2019-12-17 | ||
| US202063059638P | 2020-07-31 | 2020-07-31 | |
| US63/059,638 | 2020-07-31 | ||
| PCT/US2020/065617 WO2021127184A1 (en) | 2019-12-17 | 2020-12-17 | MANAbodies TARGETING TUMOR ANTIGENS AND METHODS OF USING |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023507729A JP2023507729A (ja) | 2023-02-27 |
| JP2023507729A5 true JP2023507729A5 (https=) | 2023-12-22 |
Family
ID=76478564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022536937A Pending JP2023507729A (ja) | 2019-12-17 | 2020-12-17 | 腫瘍抗原を標的とするｍａｎａボディおよび使用方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230051847A1 (https=) |
| EP (1) | EP4077370A4 (https=) |
| JP (1) | JP2023507729A (https=) |
| CN (1) | CN115210255A (https=) |
| AU (1) | AU2020407591A1 (https=) |
| CA (1) | CA3164446A1 (https=) |
| WO (1) | WO2021127184A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2018269370B2 (en) | 2017-05-16 | 2025-06-05 | The Johns Hopkins University | Manabodies and methods of using |
| LT3428194T (lt) | 2017-07-14 | 2021-12-10 | Immatics Biotechnologies Gmbh | Pagerinta dvejopo savitumo polipeptido molekulė |
| WO2022233956A1 (en) | 2021-05-05 | 2022-11-10 | Immatics Biotechnologies Gmbh | Antigen binding proteins specifically binding prame |
| IL313491A (en) * | 2021-12-16 | 2024-08-01 | Univ Johns Hopkins | Managbodies directed to P53 tumor antigens and methods of use |
| IL318933A (en) * | 2022-08-18 | 2025-04-01 | Immunocore Ltd | Multi-functional binding molecules |
| EP4474016A1 (en) * | 2023-06-07 | 2024-12-11 | Julius-Maximilians-Universität Würzburg | Strategies to target extracellularly accessible ras protein |
| AU2024325783A1 (en) * | 2023-08-11 | 2026-02-26 | Kelonia Therapeutics, Inc. | Compositions for modifying cells |
| AU2024353243A1 (en) | 2023-09-25 | 2026-04-09 | Kelonia Therapeutics, Inc. | Antigen binding polypeptides |
| AU2024353718A1 (en) | 2023-09-25 | 2026-04-09 | Kelonia Therapeutics, Inc. | Compositions for treating cancer |
| WO2025217204A1 (en) * | 2024-04-08 | 2025-10-16 | The Johns Hopkins University | Methods and materials for treating p53+ cancers |
| EP4659812A1 (en) * | 2024-06-07 | 2025-12-10 | Bumm, Thomas | Detection methods and combination therapies of cells with extracellular ras expression |
| CN119498254B (zh) * | 2024-12-06 | 2025-10-24 | 北京肿瘤医院(北京大学肿瘤医院) | 小鼠胃癌自发瘤模型的构建方法与应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016154246A1 (en) * | 2015-03-23 | 2016-09-29 | The Johns Hopkins University | Hla-restricted epitopes encoded by somatically mutated genes |
| GB201617564D0 (en) * | 2016-10-17 | 2016-11-30 | Agency For Science Technology And Research And National University Of Singapore And Singapore Health | Anti-p53 antibodies |
| CN108250301A (zh) * | 2016-12-29 | 2018-07-06 | 天津天锐生物科技有限公司 | 一种多靶点嵌合抗原受体 |
| EP3599250A4 (en) * | 2017-01-24 | 2021-06-09 | Benhealth Biopharmaceutic (Shenzhen) Co., Ltd. | ANTIBODY CONJUGATE AND RELATED PHARMACEUTICAL COMPOSITION AND APPLICATION |
| AU2018269370B2 (en) * | 2017-05-16 | 2025-06-05 | The Johns Hopkins University | Manabodies and methods of using |
| SG11202002635RA (en) * | 2017-09-29 | 2020-04-29 | The United States Of America As Represented By The Secretary | Methods of isolating t cells having antigenic specificity for a p53 cancer-specific mutation |
| EP3755802A4 (en) * | 2018-02-21 | 2021-11-17 | Singapore Health Services Pte Ltd | Cancer therapeutic targeting using mutant p53-specific sirnas |
-
2020
- 2020-12-17 WO PCT/US2020/065617 patent/WO2021127184A1/en not_active Ceased
- 2020-12-17 JP JP2022536937A patent/JP2023507729A/ja active Pending
- 2020-12-17 US US17/783,506 patent/US20230051847A1/en active Pending
- 2020-12-17 CA CA3164446A patent/CA3164446A1/en active Pending
- 2020-12-17 CN CN202080096879.8A patent/CN115210255A/zh active Pending
- 2020-12-17 EP EP20902329.0A patent/EP4077370A4/en active Pending
- 2020-12-17 AU AU2020407591A patent/AU2020407591A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023507729A5 (https=) | ||
| JP2024023228A5 (https=) | ||
| KR102952460B1 (ko) | Cd3 항체 및 그의 약제학적 용도 | |
| JP2022512684A5 (https=) | ||
| JP2020508655A5 (https=) | ||
| JP2025065142A5 (https=) | ||
| CN115052893A (zh) | 抗tigit抗体和使用方法 | |
| JP2019519492A5 (https=) | ||
| JP2022545647A5 (https=) | ||
| JP2020533311A5 (ja) | ＮＫＧ２Ｄ、ＣＤ１６およびＮｅｃｔｉｎ４に結合するタンパク質 | |
| JP2017504578A5 (https=) | ||
| JP2022512653A5 (https=) | ||
| JP2020525032A5 (https=) | ||
| RU2019126655A (ru) | Нуклеиновые кислоты, кодирующие химерные рецепторы, полипептидные химерные рецепторы, кодируемые ими, векторы экспрессии, содержащие их, выделенные клетки-хозяева, содержащие их, композиции, содержащие выделенные клетки-хозяева, а также способы получения выделенных клеток-хозяев in vitro, способы выбора нуклеиновых кислот, кодирующих химерные рецепторы, in vitro и способы проведения клеточной иммунотерапии у субъекта, имеющего опухоль | |
| CN112969476B (zh) | 多特异性蛋白分子 | |
| JP2020508334A5 (https=) | ||
| JP2022504802A5 (https=) | ||
| JP2020522473A5 (https=) | ||
| JP2019525738A5 (https=) | ||
| JP2019524693A5 (https=) | ||
| JP2024532485A5 (https=) | ||
| JP2018517431A5 (https=) | ||
| CN110799540A (zh) | 多特异性抗体及其制备和使用方法 | |
| CN115066274A (zh) | 三价结合分子 | |
| JP2024508672A5 (https=) |