JP2023506017A5 - - Google Patents

Info

Publication number
JP2023506017A5
JP2023506017A5 JP2022535811A JP2022535811A JP2023506017A5 JP 2023506017 A5 JP2023506017 A5 JP 2023506017A5 JP 2022535811 A JP2022535811 A JP 2022535811A JP 2022535811 A JP2022535811 A JP 2022535811A JP 2023506017 A5 JP2023506017 A5 JP 2023506017A5
Authority
JP
Japan
Prior art keywords
antigen
binding site
seq
amino acid
acid sequences
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022535811A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023506017A (ja
JP7780434B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/064706 external-priority patent/WO2021119551A1/en
Publication of JP2023506017A publication Critical patent/JP2023506017A/ja
Publication of JP2023506017A5 publication Critical patent/JP2023506017A5/ja
Application granted granted Critical
Publication of JP7780434B2 publication Critical patent/JP7780434B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022535811A 2019-12-11 2020-12-11 抗cd19抗体および多重特異性結合タンパク質 Active JP7780434B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962946931P 2019-12-11 2019-12-11
US62/946,931 2019-12-11
PCT/US2020/064706 WO2021119551A1 (en) 2019-12-11 2020-12-11 Anti-cd19 antibodies and multi-specific binding proteins

Publications (3)

Publication Number Publication Date
JP2023506017A JP2023506017A (ja) 2023-02-14
JP2023506017A5 true JP2023506017A5 (https=) 2023-12-15
JP7780434B2 JP7780434B2 (ja) 2025-12-04

Family

ID=76329102

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022535811A Active JP7780434B2 (ja) 2019-12-11 2020-12-11 抗cd19抗体および多重特異性結合タンパク質

Country Status (8)

Country Link
US (1) US12428480B2 (https=)
EP (1) EP4073122A4 (https=)
JP (1) JP7780434B2 (https=)
CN (1) CN115916818A (https=)
AU (1) AU2020403273A1 (https=)
CA (1) CA3161283A1 (https=)
IL (1) IL293725A (https=)
WO (1) WO2021119551A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL293725A (en) 2019-12-11 2022-08-01 Cullinan Oncology Inc Anti-cd19 antibodies and multispecific binding proteins
IL308258A (en) 2021-05-05 2024-01-01 Immatics Biotechnologies Gmbh Bma031 antigen binding polypeptides
KR20260020379A (ko) * 2023-04-07 2026-02-11 쿨리난 테라퓨틱스, 인코포레이티드 다중특이적 결합 단백질의 사용 방법
WO2025165980A1 (en) * 2024-01-31 2025-08-07 Cullinan Therapeutics, Inc. Therapies for autoimmune disorders

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9321832B2 (en) 2002-06-28 2016-04-26 Domantis Limited Ligand
US10000574B2 (en) 2003-11-28 2018-06-19 Amgen Research (Munich) Gmbh Compositions comprising polypeptides
CN101128487B (zh) 2004-12-02 2012-10-10 杜门蒂斯有限公司 靶向血清白蛋白和glp-1或pyy的双特异性结构域抗体
HRP20150175T1 (en) 2005-12-16 2015-03-27 Amgen Research (Munich) Gmbh Means and methods for the treatment of tumorous diseases
DK2211904T3 (en) 2007-10-19 2016-10-24 Seattle Genetics Inc Cd19-binding agents and uses thereof
EP2673297A2 (en) 2011-02-11 2013-12-18 Zyngenia, Inc. Monovalent and multivalent multispecific complexes and uses thereof
US9527925B2 (en) 2011-04-01 2016-12-27 Boehringer Ingelheim International Gmbh Bispecific binding molecules binding to VEGF and ANG2
WO2013013700A1 (en) 2011-07-22 2013-01-31 Affimed Therapeutics Ag Multivalent antigen-binding fv molecule
PE20141522A1 (es) 2011-08-17 2014-11-17 Glaxo Group Ltd Proteinas y peptidos modificados
WO2014012082A2 (en) 2012-07-13 2014-01-16 Zymeworks Inc. Multivalent heteromultimer scaffold design an constructs
AU2013289883B2 (en) 2012-07-13 2018-11-01 Zymeworks Bc Inc. Bispecific asymmetric heterodimers comprising anti-CD3 constructs
JP2017512814A (ja) 2014-04-07 2017-05-25 シアトル ジェネティックス, インコーポレイテッド 抗cd19抗体および抗体−薬物結合体のための安定な製剤
UY36245A (es) 2014-07-31 2016-01-29 Amgen Res Munich Gmbh Constructos de anticuerpos para cdh19 y cd3
CN120988137A (zh) 2015-01-23 2025-11-21 赛诺菲 抗cd3抗体、抗cd123抗体和与cd3和/或cd123特异性结合的双特异性抗体
CN107406507A (zh) 2015-02-12 2017-11-28 西雅图基因公司 使用cd19‑adc和长春新碱的组合疗法
CN114920848B (zh) 2015-05-13 2024-10-11 埃博灵克斯股份有限公司 基于cd3反应性的t细胞募集多肽
US9708412B2 (en) 2015-05-21 2017-07-18 Harpoon Therapeutics, Inc. Trispecific binding proteins and methods of use
EP3322735A4 (en) 2015-07-15 2019-03-13 Zymeworks Inc. ACTIVE CONJUGATED BIS-SPECIFIC ANTIGEN-BONDING CONSTRUCTS
IL319047A (en) 2015-08-28 2025-04-01 Amunix Operating Inc Chimeric polypeptide composition and methods for its preparation and use
WO2017055314A1 (en) 2015-10-02 2017-04-06 F. Hoffmann-La Roche Ag Bispecific anti-cd19xcd3 t cell activating antigen binding molecules
AU2016330807B2 (en) * 2015-10-02 2023-08-10 F. Hoffmann-La Roche Ag Anti-human CD19 antibodies with high affinity
AU2016357460B2 (en) * 2015-11-18 2023-07-27 Ablynx Nv Improved serum albumin binders
CN105399832A (zh) 2015-12-07 2016-03-16 四川大学 一种无标签单链型人源双特异性抗体及其用途
KR20180133442A (ko) 2016-04-13 2018-12-14 비비아 바이오테크 에스.엘. 생체외 bite 활성화된 t 세포
EP3243836A1 (en) 2016-05-11 2017-11-15 F. Hoffmann-La Roche AG C-terminally fused tnf family ligand trimer-containing antigen binding molecules
WO2018098356A1 (en) 2016-11-23 2018-05-31 Harpoon Therapeutics, Inc. Psma targeting trispecific proteins and methods of use
FR3068662B1 (fr) 2017-07-04 2019-08-30 Le Joint Francais Snc Passe-cloison pour un organe destine a traverser une cloison
WO2019077062A1 (en) 2017-10-18 2019-04-25 Vivia Biotech, S.L. C-CELLS ACTIVATED BY BIT
JP7383704B2 (ja) * 2018-06-07 2023-11-20 カリナン オンコロジー インコーポレイテッド 多重特異性結合タンパク質およびその使用方法
US10815311B2 (en) * 2018-09-25 2020-10-27 Harpoon Therapeutics, Inc. DLL3 binding proteins and methods of use
IL293725A (en) 2019-12-11 2022-08-01 Cullinan Oncology Inc Anti-cd19 antibodies and multispecific binding proteins
IL293780A (en) 2019-12-11 2022-08-01 Cullinan Man Inc Anti-serum albumin antibodies

Similar Documents

Publication Publication Date Title
JP2025111463A5 (https=)
JP2023506017A5 (https=)
JP2024038003A5 (https=)
JP2022177090A5 (https=)
JP2024167313A5 (https=)
RU2013125306A (ru) Связывающие протеины, специфичные по отношению к инсулин-подобным факторам роста, и их использование
JP2023506834A5 (https=)
JP2020536109A5 (https=)
CN116396386A (zh) Cd3抗体及其药物用途
JP2022533538A5 (https=)
RU2012112829A (ru) Анти-gitr-антитела
RU2020130795A (ru) Нейтрализующие антитела к env вич-1 и их применение
AR069062A1 (es) Anticuerpo anti-hepcidina
RU2018120695A (ru) Связывающие молекулы, специфичные в отношении asct2, и их применения
JP2024506315A5 (https=)
JP2025038088A5 (https=)
JP2020515277A5 (https=)
JP2024540148A5 (https=)
CN111712521A (zh) Cd38蛋白抗体及其应用
JP2021512652A5 (https=)
JP2023545183A5 (https=)
JP2024516098A5 (https=)
JP2017511152A5 (https=)
CN107488230A (zh) 一种抗人CD79a胞外端蛋白的抗体、编码基因及应用
IL278323B1 (en) Antibodies directed against glycoprotein IV