JP2023504661A5 - - Google Patents
Info
- Publication number
- JP2023504661A5 JP2023504661A5 JP2022533139A JP2022533139A JP2023504661A5 JP 2023504661 A5 JP2023504661 A5 JP 2023504661A5 JP 2022533139 A JP2022533139 A JP 2022533139A JP 2022533139 A JP2022533139 A JP 2022533139A JP 2023504661 A5 JP2023504661 A5 JP 2023504661A5
- Authority
- JP
- Japan
- Prior art keywords
- substitution
- variant
- trna
- optionally
- manipulated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962942667P | 2019-12-02 | 2019-12-02 | |
| US201962942690P | 2019-12-02 | 2019-12-02 | |
| US62/942,667 | 2019-12-02 | ||
| US62/942,690 | 2019-12-02 | ||
| US202063010856P | 2020-04-16 | 2020-04-16 | |
| US63/010,856 | 2020-04-16 | ||
| US202063111856P | 2020-11-10 | 2020-11-10 | |
| US63/111,856 | 2020-11-10 | ||
| PCT/US2020/062671 WO2021113218A1 (en) | 2019-12-02 | 2020-12-01 | Targeted transfer rnas for treatment of diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023504661A JP2023504661A (ja) | 2023-02-06 |
| JP2023504661A5 true JP2023504661A5 (https=) | 2023-12-08 |
Family
ID=74046150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022533139A Pending JP2023504661A (ja) | 2019-12-02 | 2020-12-01 | 疾患の処置のための標的化トランスファーｒｎａ |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP4069841A1 (https=) |
| JP (1) | JP2023504661A (https=) |
| CN (1) | CN115397983A (https=) |
| AU (1) | AU2020396868A1 (https=) |
| CA (1) | CA3163514A1 (https=) |
| WO (1) | WO2021113218A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102930465B1 (ko) | 2017-11-02 | 2026-02-25 | 더 위스타 인스티튜트 오브 아나토미 앤드 바이올로지 | ACE-tRNA를 이용한 유전 재할당을 통한 정지 코돈의 구조 방법 |
| MX2022012955A (es) | 2020-04-14 | 2023-02-23 | Flagship Pioneering Innovations Vi Llc | Composiciones de trem y usos de las mismas. |
| WO2023097268A2 (en) * | 2021-11-23 | 2023-06-01 | Mantra Bio, Inc. | Extracellular vesicles comprising non-naturally occurring modular rna hairpins and uses thereof |
| WO2023220342A2 (en) | 2022-05-13 | 2023-11-16 | Shape Therapeutics Inc. | Engineered tranfer rnas |
| WO2024149415A1 (en) * | 2023-01-10 | 2024-07-18 | Biologicke Centrum Av Cr, V. V. I. | Altered trnas for treatment of genetic diseases caused by premature termination codon |
| WO2024197081A1 (en) * | 2023-03-20 | 2024-09-26 | Hc Bioscience, Inc. | Minimally-sized dna threads for trna therapy |
| EP4442826A1 (en) | 2023-04-06 | 2024-10-09 | Universität Hamburg | Synthetic dna construct encoding transfer rna |
| EP4458967A1 (en) | 2023-05-02 | 2024-11-06 | Universität Hamburg | Pharmaceutical composition comprising multiple suppressor transfer rnas |
| TW202504646A (zh) * | 2023-06-16 | 2025-02-01 | 北京大學 | 利用環狀ｒｎａ抑制無義介導的降解的系統和方法 |
| WO2025036281A1 (en) * | 2023-08-11 | 2025-02-20 | Shanghai Codone Biotechnology Co. | Engineered suppressor trna molecules and methods |
| WO2026001270A1 (en) * | 2024-06-24 | 2026-01-02 | Zhuhai Codone Biotechnology Co., Ltd. | Engineered trna molecules and methods |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012006551A2 (en) * | 2010-07-08 | 2012-01-12 | The Brigham And Women's Hospital, Inc. | Neuroprotective molecules and methods of treating neurological disorders and inducing stress granules |
| IL310721B2 (en) * | 2015-10-23 | 2025-11-01 | Harvard College | Nucleobase editors and uses thereof |
| CN110612353A (zh) * | 2017-03-03 | 2019-12-24 | 加利福尼亚大学董事会 | 经由抑制性tRNAs和脱氨酶对突变进行RNA靶向 |
| KR102930465B1 (ko) * | 2017-11-02 | 2026-02-25 | 더 위스타 인스티튜트 오브 아나토미 앤드 바이올로지 | ACE-tRNA를 이용한 유전 재할당을 통한 정지 코돈의 구조 방법 |
| US10968257B2 (en) * | 2018-04-03 | 2021-04-06 | The Broad Institute, Inc. | Target recognition motifs and uses thereof |
| CA3125567A1 (en) * | 2019-01-18 | 2020-07-23 | Flagship Pioneering, Inc. | Trem compositions and uses thereof |
-
2020
- 2020-12-01 WO PCT/US2020/062671 patent/WO2021113218A1/en not_active Ceased
- 2020-12-01 JP JP2022533139A patent/JP2023504661A/ja active Pending
- 2020-12-01 CN CN202080093906.6A patent/CN115397983A/zh active Pending
- 2020-12-01 AU AU2020396868A patent/AU2020396868A1/en not_active Abandoned
- 2020-12-01 EP EP20829427.2A patent/EP4069841A1/en not_active Withdrawn
- 2020-12-01 CA CA3163514A patent/CA3163514A1/en active Pending
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