JP2023504048A5 - - Google Patents
Info
- Publication number
- JP2023504048A5 JP2023504048A5 JP2022530897A JP2022530897A JP2023504048A5 JP 2023504048 A5 JP2023504048 A5 JP 2023504048A5 JP 2022530897 A JP2022530897 A JP 2022530897A JP 2022530897 A JP2022530897 A JP 2022530897A JP 2023504048 A5 JP2023504048 A5 JP 2023504048A5
- Authority
- JP
- Japan
- Prior art keywords
- target
- circular guide
- artificial
- rna sequence
- guide rna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962942725P | 2019-12-02 | 2019-12-02 | |
| US62/942,725 | 2019-12-02 | ||
| US202063112492P | 2020-11-11 | 2020-11-11 | |
| US63/112,492 | 2020-11-11 | ||
| PCT/US2020/062748 WO2021113264A1 (en) | 2019-12-02 | 2020-12-01 | Engineering circular guide rnas |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023504048A JP2023504048A (ja) | 2023-02-01 |
| JP2023504048A5 true JP2023504048A5 (enExample) | 2023-12-04 |
Family
ID=76221931
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022530897A Pending JP2023504048A (ja) | 2019-12-02 | 2020-12-01 | 環状ガイドｒｎａの遺伝子操作 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230036370A1 (enExample) |
| EP (1) | EP4069830A4 (enExample) |
| JP (1) | JP2023504048A (enExample) |
| CN (1) | CN115210366A (enExample) |
| AU (1) | AU2020395111A1 (enExample) |
| CA (1) | CA3159799A1 (enExample) |
| WO (1) | WO2021113264A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230055682A1 (en) * | 2019-12-03 | 2023-02-23 | Beam Therapeutics lnc. | Synthetic guide rna, compositions, methods, and uses thereof |
| US20230059753A1 (en) * | 2019-12-09 | 2023-02-23 | Astellas Pharma Inc. | Antisense guide rna with added functional region for editing target rna |
| JP2023528039A (ja) * | 2020-05-26 | 2023-07-03 | シェイプ セラピューティクス インコーポレイテッド | 改変環状ポリヌクレオチド |
| WO2022147573A1 (en) * | 2021-01-04 | 2022-07-07 | The Regents Of The University Of California | Programmable rna editing in vivo via recruitment of endogenous adars |
| JP2024504608A (ja) * | 2021-01-12 | 2024-02-01 | 北京大学 | 遺伝子操作ｒｎａを使用した内因性ａｄａｒの活用による標的化ｒｎａの編集 |
| EP4423274A2 (en) * | 2021-10-26 | 2024-09-04 | Shape Therapeutics Inc. | Rna-editing compositions and methods of use |
| EP4667570A1 (en) * | 2024-06-20 | 2025-12-24 | Johannes Gutenberg-Universität Mainz | Nucleic acid molecule complex for target pseudouridylation in mammalian cells |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2925866T3 (en) * | 2012-11-30 | 2018-10-29 | Univ Aarhus | CIRCULAR RNA FOR INHIBITING MICRO-RNA |
| CN120574876A (zh) * | 2013-08-22 | 2025-09-02 | 纳幕尔杜邦公司 | 使用向导rna/cas内切核酸酶系统的植物基因组修饰及其使用方法 |
| WO2018237372A1 (en) * | 2017-06-23 | 2018-12-27 | Cornell University | RNA MOLECULES, METHODS FOR PRODUCING CIRCULAR RNA, AND METHODS OF TREATMENT |
| KR102761791B1 (ko) * | 2017-06-26 | 2025-02-05 | 더 브로드 인스티튜트, 인코퍼레이티드 | 표적화된 핵산 편집을 위한 crispr/cas-아데닌 데아미나아제 기반 조성물, 시스템 및 방법 |
| US20200362334A1 (en) * | 2017-12-07 | 2020-11-19 | The Broad Institute, Inc. | High-throughput methods for identifying gene interactions and networks |
| CN111819185A (zh) * | 2017-12-15 | 2020-10-23 | 旗舰创业创新第六有限责任公司 | 包含环状多核糖核苷酸的组合物及其用途 |
| US20220010333A1 (en) * | 2018-09-06 | 2022-01-13 | The Regents Of The University Of California | Rna and dna base editing via engineered adar recruitment |
| EP3997229A4 (en) * | 2019-07-12 | 2024-07-03 | Peking University | TARGETED RNA EDITING BY HARNESSING ENDOGENOUS ADAR USING MODIFIED RNA |
| JP2023528039A (ja) * | 2020-05-26 | 2023-07-03 | シェイプ セラピューティクス インコーポレイテッド | 改変環状ポリヌクレオチド |
-
2020
- 2020-12-01 WO PCT/US2020/062748 patent/WO2021113264A1/en not_active Ceased
- 2020-12-01 EP EP20895262.2A patent/EP4069830A4/en active Pending
- 2020-12-01 JP JP2022530897A patent/JP2023504048A/ja active Pending
- 2020-12-01 CA CA3159799A patent/CA3159799A1/en active Pending
- 2020-12-01 AU AU2020395111A patent/AU2020395111A1/en active Pending
- 2020-12-01 US US17/781,686 patent/US20230036370A1/en active Pending
- 2020-12-01 CN CN202080094276.4A patent/CN115210366A/zh active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023504048A5 (enExample) | ||
| JP2022535911A5 (enExample) | ||
| JP2021113232A (ja) | ペプチドオリゴヌクレオチドコンジュゲート | |
| JP2020503049A5 (enExample) | ||
| KR20240063964A (ko) | 올리고뉴클레오티드 조성물 및 이의 방법 | |
| JP7515400B2 (ja) | Ｂ型肝炎ウイルス感染を治療するためのｆｕｂｐ１阻害剤の使用 | |
| RU2015151202A (ru) | Композиции и способы модулирования экспрессии hbv и ttr | |
| RU2017101172A (ru) | Антисмысловые нуклеиновые кислоты | |
| JP2021529173A5 (enExample) | ||
| WO1990014090A1 (en) | SHORT THERAPEUTIC dsRNA OF DEFINED STRUCTURE | |
| JP2016000059A (ja) | 修飾されたサブユニット間結合および／または末端基を有するオリゴヌクレオチドアナログ | |
| JP2006511490A5 (enExample) | ||
| JP7363316B2 (ja) | ヘアピン型一本鎖ｒｎａ分子の製造方法 | |
| WO2018182008A1 (ja) | 遺伝子発現制御機能を有する環状型核酸分子 | |
| JP2017510293A5 (enExample) | ||
| EP4702145A2 (en) | Modified guide rna | |
| JP2020525502A5 (enExample) | ||
| JP2021524277A (ja) | Ｒｔｅｌ１発現の調節用のオリゴヌクレオチド | |
| Moon et al. | Stereoselective synthesis of a novel apio analogue of neplanocin A as potential S-adenosylhomocysteine hydrolase inhibitor | |
| RU2008106762A (ru) | Новые карбосилановые дендримеры, их получение и применение | |
| JP2021514368A5 (enExample) | ||
| JP2004526737A5 (enExample) | ||
| JP2006515854A5 (enExample) | ||
| CN115768439A (zh) | 双链siRNA类似物的缀合物 | |
| JPWO2022270487A5 (enExample) |