JP2023503985A5 - - Google Patents
Info
- Publication number
- JP2023503985A5 JP2023503985A5 JP2022530757A JP2022530757A JP2023503985A5 JP 2023503985 A5 JP2023503985 A5 JP 2023503985A5 JP 2022530757 A JP2022530757 A JP 2022530757A JP 2022530757 A JP2022530757 A JP 2022530757A JP 2023503985 A5 JP2023503985 A5 JP 2023503985A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- base
- nucleoside
- group
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025074104A JP2025105841A (ja) | 2019-11-27 | 2025-04-28 | ３’－ｒｎａオリゴヌクレオチドの合成 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962941153P | 2019-11-27 | 2019-11-27 | |
| US62/941,153 | 2019-11-27 | ||
| PCT/US2020/061755 WO2021108291A1 (en) | 2019-11-27 | 2020-11-23 | Synthesis of 3'-rna oligonucleotides |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025074104A Division JP2025105841A (ja) | 2019-11-27 | 2025-04-28 | ３’－ｒｎａオリゴヌクレオチドの合成 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023503985A JP2023503985A (ja) | 2023-02-01 |
| JP2023503985A5 true JP2023503985A5 (https=) | 2023-10-03 |
| JP7675716B2 JP7675716B2 (ja) | 2025-05-13 |
Family
ID=76129612
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022530757A Active JP7675716B2 (ja) | 2019-11-27 | 2020-11-23 | ３’－ｒｎａオリゴヌクレオチドの合成 |
| JP2025074104A Pending JP2025105841A (ja) | 2019-11-27 | 2025-04-28 | ３’－ｒｎａオリゴヌクレオチドの合成 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025074104A Pending JP2025105841A (ja) | 2019-11-27 | 2025-04-28 | ３’－ｒｎａオリゴヌクレオチドの合成 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20250325575A2 (https=) |
| EP (1) | EP4065715A4 (https=) |
| JP (2) | JP7675716B2 (https=) |
| KR (1) | KR20220107246A (https=) |
| CN (2) | CN118791543A (https=) |
| AU (1) | AU2020391116A1 (https=) |
| CA (1) | CA3162717A1 (https=) |
| IL (2) | IL293327B2 (https=) |
| MX (1) | MX2022006221A (https=) |
| WO (1) | WO2021108291A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2026085164A2 (en) | 2024-10-16 | 2026-04-23 | Alnylam Pharmaceuticals, Inc. | Snca irna formulations and methods of use thereof |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4924624A (en) * | 1987-10-22 | 1990-05-15 | Temple University-Of The Commonwealth System Of Higher Education | 2,',5'-phosphorothioate oligoadenylates and plant antiviral uses thereof |
| ATE299509T1 (de) * | 1992-07-23 | 2005-07-15 | Isis Pharmaceuticals Inc | Neue 2'-o-alkyl-nukleoside und -phosphoramidite, verfahren zu ihrer herstellung und ihre verwendungen |
| US6649750B1 (en) * | 2000-01-05 | 2003-11-18 | Isis Pharmaceuticals, Inc. | Process for the preparation of oligonucleotide compounds |
| WO2002018405A2 (en) * | 2000-09-01 | 2002-03-07 | Ribozyme Pharmaceuticals, Incorporated | Methods for synthesizing nucleosides, nucleoside derivatives and non-nucleoside derivatives |
| US7211654B2 (en) * | 2001-03-14 | 2007-05-01 | Regents Of The University Of Michigan | Linkers and co-coupling agents for optimization of oligonucleotide synthesis and purification on solid supports |
| WO2003039523A2 (en) * | 2001-11-05 | 2003-05-15 | Exiqon A/S | OLIGONUCLEOTIDES MODIFIED WITH NOVEL α-L-RNA ANALOGUES |
| CN100484949C (zh) * | 2005-07-18 | 2009-05-06 | 张必良 | 用于rna寡核苷酸合成中的核苷亚磷酰胺及其合成方法 |
| US8911948B2 (en) * | 2008-04-30 | 2014-12-16 | Integrated Dna Technologies, Inc. | RNase H-based assays utilizing modified RNA monomers |
| US8309707B2 (en) * | 2008-09-06 | 2012-11-13 | Chemgenes Corporation | RNA synthesis-phosphoramidites for synthetic RNA in the reverse direction, and application in convenient introduction of ligands, chromophores and modifications of synthetic RNA at the 3′-end |
| US8541569B2 (en) * | 2008-09-06 | 2013-09-24 | Chemgenes Corporation | Phosphoramidites for synthetic RNA in the reverse direction, efficient RNA synthesis and convenient introduction of 3'-end ligands, chromophores and modifications of synthetic RNA |
| CA2844769A1 (en) | 2010-08-23 | 2012-03-01 | The Royal Institution For The Advancement Of Learning/Mcgill University | Block synthesis of oligoribonucleotides |
| CA2900238A1 (en) * | 2013-02-22 | 2014-08-28 | Sirna Therapeutics, Inc. | Short interfering nucleic acid (sina) molecules containing a 2' internucleoside linkage |
| EP3154996B1 (en) * | 2014-06-10 | 2020-03-11 | Agilent Technologies, Inc. | Protecting groups for "z nucleotide" and methods thereof |
| EP3455232B1 (en) * | 2016-05-12 | 2020-05-06 | Roche Innovation Center Copenhagen A/S | Enhanced coupling of stereodefined oxazaphospholidine phosphoramidite monomers to nucleoside or oligonucleotide |
| WO2018019748A1 (en) * | 2016-07-27 | 2018-02-01 | F. Hoffmann-La Roche Ag | 5's-lna nucleotides and oligonucleotides |
-
2020
- 2020-11-22 IL IL293327A patent/IL293327B2/en unknown
- 2020-11-23 MX MX2022006221A patent/MX2022006221A/es unknown
- 2020-11-23 CN CN202410795160.3A patent/CN118791543A/zh active Pending
- 2020-11-23 AU AU2020391116A patent/AU2020391116A1/en active Pending
- 2020-11-23 WO PCT/US2020/061755 patent/WO2021108291A1/en not_active Ceased
- 2020-11-23 CA CA3162717A patent/CA3162717A1/en active Pending
- 2020-11-23 CN CN202080094679.9A patent/CN115038790B/zh active Active
- 2020-11-23 KR KR1020227021711A patent/KR20220107246A/ko active Pending
- 2020-11-23 JP JP2022530757A patent/JP7675716B2/ja active Active
- 2020-11-23 EP EP20892935.6A patent/EP4065715A4/en active Pending
- 2020-11-23 US US17/779,706 patent/US20250325575A2/en active Pending
-
2025
- 2025-04-28 JP JP2025074104A patent/JP2025105841A/ja active Pending
- 2025-10-23 IL IL324170A patent/IL324170A/en unknown
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