JP2023503470A5 - - Google Patents
Info
- Publication number
- JP2023503470A5 JP2023503470A5 JP2022530701A JP2022530701A JP2023503470A5 JP 2023503470 A5 JP2023503470 A5 JP 2023503470A5 JP 2022530701 A JP2022530701 A JP 2022530701A JP 2022530701 A JP2022530701 A JP 2022530701A JP 2023503470 A5 JP2023503470 A5 JP 2023503470A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- membered
- heteroaryl
- aryl
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19383036.1 | 2019-11-25 | ||
| EP19383036 | 2019-11-25 | ||
| PCT/IB2020/061156 WO2021105906A1 (en) | 2019-11-25 | 2020-11-25 | Aryl and heteroaryl compounds, and therapeutic uses thereof in conditions associated with the alteration of the activity of galactocerebrosidase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023503470A JP2023503470A (ja) | 2023-01-30 |
| JP2023503470A5 true JP2023503470A5 (https=) | 2023-11-24 |
Family
ID=68808238
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022530701A Pending JP2023503470A (ja) | 2019-11-25 | 2020-11-25 | ガラクトセレブロシダーゼの活性の変質に関連する状態におけるアリールおよびヘテロアリール化合物、ならびにそれらの治療的使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230058312A1 (https=) |
| EP (1) | EP4065546A1 (https=) |
| JP (1) | JP2023503470A (https=) |
| KR (1) | KR20220150880A (https=) |
| CN (1) | CN115397806A (https=) |
| AU (1) | AU2020393174A1 (https=) |
| BR (1) | BR112022010127A2 (https=) |
| CA (1) | CA3158290A1 (https=) |
| IL (1) | IL293409A (https=) |
| MX (1) | MX2022006059A (https=) |
| WO (1) | WO2021105906A1 (https=) |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4500714A (en) * | 1981-10-15 | 1985-02-19 | Chugai Seiyaku Kabushiki Kaisha | 3-Substituted-ureido-N-pyridyl benzamides |
| US6995162B2 (en) * | 2001-01-12 | 2006-02-07 | Amgen Inc. | Substituted alkylamine derivatives and methods of use |
| WO2004092177A1 (en) * | 2003-04-09 | 2004-10-28 | Biogen Idec Ma Inc. | Triazolopyrazines and methods of making and using the same |
| EP1644334B1 (en) * | 2003-05-30 | 2008-01-02 | Eli Lilly and Company | Antithrombotic ethers |
| WO2005049604A2 (en) * | 2003-09-30 | 2005-06-02 | Eli Lilly And Company | Antithrombotic aromatic ethers |
| WO2005085188A2 (en) * | 2004-03-02 | 2005-09-15 | Compass Pharmaceuticals Llc | Compounds and methods for anti-tumor therapy |
| SE0401343D0 (sv) * | 2004-05-25 | 2004-05-25 | Astrazeneca Ab | Therapeutic compounds: Pyridine N oxide as scaffold |
| SE0401345D0 (sv) * | 2004-05-25 | 2004-05-25 | Astrazeneca Ab | Therapeutic compounds: Pyridine as scaffold |
| US8354427B2 (en) * | 2004-06-24 | 2013-01-15 | Vertex Pharmaceutical Incorporated | Modulators of ATP-binding cassette transporters |
| US7470787B2 (en) * | 2005-07-11 | 2008-12-30 | Aerie Pharmaceuticals, Inc. | Isoquinoline compounds |
| EP1945632B1 (en) * | 2005-11-08 | 2013-09-18 | Vertex Pharmaceuticals Incorporated | Heterocyclic modulators of atp-binding cassette transporters |
| AU2006336504C9 (en) * | 2005-12-28 | 2015-05-14 | Vertex Pharmaceuticals Incorporated | 1-(benzo [D] [1,3] dioxol-5-yl) -N- (phenyl) cyclopropane- carboxamide derivatives and related compounds as modulators of ATP-Binding Cassette transporters for the treatment of Cystic Fibrosis |
| CN101790519B (zh) * | 2007-08-08 | 2013-10-16 | 默克雪兰诺有限公司 | 用于治疗多发性硬化症的结合于鞘氨醇1-磷酸(s1p)的6-氨基-嘧啶-4-羧酰胺衍生物及相关化合物 |
| JP2011526925A (ja) * | 2008-07-01 | 2011-10-20 | ザカロン ファーマシューティカルズ，インク． | ヘパラン硫酸阻害剤 |
| WO2010111713A2 (en) * | 2009-03-27 | 2010-09-30 | Zacharon Pharmaceuticals, Inc. | N-linked glycan biosynthesis modulators |
| SI2995306T1 (sl) | 2009-10-19 | 2019-04-30 | Amicus Therapeutics, Inc. | Novi sestavki za preprečevanje in/ali zdravljenje motenj lizosomskega shranjevanja |
| EP3366688B1 (en) * | 2010-12-08 | 2022-02-09 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | Substituted pyrazolopyrimidines as glucocerebrosidase activators |
| CN103458970A (zh) * | 2011-03-07 | 2013-12-18 | 泰莱托恩基金会 | Tfeb磷酸化抑制剂及其应用 |
| KR101987736B1 (ko) | 2011-03-18 | 2019-06-11 | 젠자임 코포레이션 | 글루코실세라마이드 합성효소 억제제 |
| WO2013078413A1 (en) * | 2011-11-22 | 2013-05-30 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Modulators of lipid storage |
| WO2015153410A1 (en) * | 2014-03-31 | 2015-10-08 | The Trustees Of Columbia University In The City Of New York | Histone acetyltransferase activators and uses thereof |
| US10201531B2 (en) * | 2015-08-12 | 2019-02-12 | Mochida Pharmaceutical Co., Ltd. | Indazolyl-oxo-isothiazole compounds |
| WO2017040971A1 (en) * | 2015-09-03 | 2017-03-09 | Biomarin Pharmaceutical Inc. | Methods of using inhibitors of pikfyve for the treatment of lysosomal storage disorders and neurodegenerative diseases |
| MX2018006856A (es) * | 2015-12-07 | 2018-08-01 | Plexxikon Inc | Compuestos y metodos para modulacion de la quinasa, e indicaciones de los mismos. |
| ES2904615T3 (es) * | 2016-03-16 | 2022-04-05 | Plexxikon Inc | Compuestos y métodos para la modulación de quinasas e indicaciones al respecto |
| CA3031365A1 (en) * | 2016-07-20 | 2018-01-25 | The Trustees Of Columbia University In The City Of New York | Histone acetyltransferase activators and compositions and uses thereof |
-
2020
- 2020-11-25 BR BR112022010127A patent/BR112022010127A2/pt not_active Application Discontinuation
- 2020-11-25 JP JP2022530701A patent/JP2023503470A/ja active Pending
- 2020-11-25 AU AU2020393174A patent/AU2020393174A1/en not_active Abandoned
- 2020-11-25 CN CN202080088133.2A patent/CN115397806A/zh active Pending
- 2020-11-25 WO PCT/IB2020/061156 patent/WO2021105906A1/en not_active Ceased
- 2020-11-25 IL IL293409A patent/IL293409A/en unknown
- 2020-11-25 KR KR1020227021341A patent/KR20220150880A/ko not_active Withdrawn
- 2020-11-25 EP EP20815951.7A patent/EP4065546A1/en active Pending
- 2020-11-25 CA CA3158290A patent/CA3158290A1/en active Pending
- 2020-11-25 US US17/779,485 patent/US20230058312A1/en active Pending
- 2020-11-25 MX MX2022006059A patent/MX2022006059A/es unknown
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