JP2023503455A5 - - Google Patents

Info

Publication number
JP2023503455A5
JP2023503455A5 JP2022529681A JP2022529681A JP2023503455A5 JP 2023503455 A5 JP2023503455 A5 JP 2023503455A5 JP 2022529681 A JP2022529681 A JP 2022529681A JP 2022529681 A JP2022529681 A JP 2022529681A JP 2023503455 A5 JP2023503455 A5 JP 2023503455A5
Authority
JP
Japan
Application number
JP2022529681A
Other languages
Japanese (ja)
Other versions
JP2023503455A (ja
JPWO2021102234A5 (https=
JP7712271B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/061464 external-priority patent/WO2021102234A1/en
Publication of JP2023503455A publication Critical patent/JP2023503455A/ja
Publication of JPWO2021102234A5 publication Critical patent/JPWO2021102234A5/ja
Publication of JP2023503455A5 publication Critical patent/JP2023503455A5/ja
Priority to JP2025044678A priority Critical patent/JP2025102825A/ja
Priority to JP2025116303A priority patent/JP2025148448A/ja
Application granted granted Critical
Publication of JP7712271B2 publication Critical patent/JP7712271B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022529681A 2019-11-22 2020-11-20 アデノ随伴ウイルスベクター変種 Active JP7712271B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2025044678A JP2025102825A (ja) 2019-11-22 2025-03-19 アデノ随伴ウイルスベクター変種
JP2025116303A JP2025148448A (ja) 2019-11-22 2025-07-10 アデノ随伴ウイルスベクター変種

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962939315P 2019-11-22 2019-11-22
US62/939,315 2019-11-22
US202063084709P 2020-09-29 2020-09-29
US63/084,709 2020-09-29
PCT/US2020/061464 WO2021102234A1 (en) 2019-11-22 2020-11-20 Adeno-associated viral vector variants

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2025044678A Division JP2025102825A (ja) 2019-11-22 2025-03-19 アデノ随伴ウイルスベクター変種
JP2025116303A Division JP2025148448A (ja) 2019-11-22 2025-07-10 アデノ随伴ウイルスベクター変種

Publications (4)

Publication Number Publication Date
JP2023503455A JP2023503455A (ja) 2023-01-30
JPWO2021102234A5 JPWO2021102234A5 (https=) 2024-01-30
JP2023503455A5 true JP2023503455A5 (https=) 2024-01-30
JP7712271B2 JP7712271B2 (ja) 2025-07-23

Family

ID=75980202

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2022529681A Active JP7712271B2 (ja) 2019-11-22 2020-11-20 アデノ随伴ウイルスベクター変種
JP2025044678A Pending JP2025102825A (ja) 2019-11-22 2025-03-19 アデノ随伴ウイルスベクター変種
JP2025116303A Pending JP2025148448A (ja) 2019-11-22 2025-07-10 アデノ随伴ウイルスベクター変種

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2025044678A Pending JP2025102825A (ja) 2019-11-22 2025-03-19 アデノ随伴ウイルスベクター変種
JP2025116303A Pending JP2025148448A (ja) 2019-11-22 2025-07-10 アデノ随伴ウイルスベクター変種

Country Status (13)

Country Link
US (2) US20230346981A1 (https=)
EP (1) EP4061427A4 (https=)
JP (3) JP7712271B2 (https=)
KR (1) KR20220116459A (https=)
CN (2) CN115023242B (https=)
AU (1) AU2020388404A1 (https=)
BR (1) BR112022009864A2 (https=)
CA (1) CA3159113A1 (https=)
CO (1) CO2022008507A2 (https=)
IL (1) IL293140A (https=)
MX (1) MX2022006188A (https=)
PH (1) PH12022551247A1 (https=)
WO (1) WO2021102234A1 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2022013030A (es) * 2020-04-17 2023-03-09 Regeneron Pharma Ensayos de deteccion para anticuerpos neutralizantes de coronavirus.
MX2024004217A (es) 2021-10-08 2024-06-26 Dyno Therapeutics Inc Variantes de cápside y métodos de uso de estas.
WO2023205397A1 (en) * 2022-04-22 2023-10-26 The Children's Hospital Of Philadelphia Human ependyma-specific promoter and uses thereof
AU2023269646A1 (en) * 2022-05-11 2024-12-05 The Children's Hospital Of Philadelphia Adeno-associated viral vectors for targeting deep brain structures
CN119562959A (zh) * 2022-05-13 2025-03-04 费城儿童医院 用于靶向脑微脉管系统的腺相关病毒载体
AU2023273809A1 (en) 2022-05-16 2025-01-02 Genzyme Corporation Methods of treating metachromatic leukodystrophy
CN119894920A (zh) 2022-07-22 2025-04-25 上海天泽云泰生物医药有限公司 用于靶向神经系统的新型aav衣壳及其用途
KR102870168B1 (ko) * 2022-08-26 2025-10-13 김선아 활막 표적화 화합물 및 이의 용도
JP2025532627A (ja) * 2022-09-19 2025-10-01 ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィア SPLiT-seqを用いたシングルセル解像でのAAV進化
IL322459A (en) * 2023-01-31 2025-09-01 Childrens Hospital Philadelphia Innovative gene therapy construct for cln2 disease
TW202502803A (zh) 2023-03-10 2025-01-16 美商戴諾治療公司 衣殼多肽及其使用方法
CN118005749B (zh) * 2023-07-21 2024-07-16 广州派真生物技术有限公司 腺相关病毒突变体及其应用
TW202525832A (zh) 2023-08-31 2025-07-01 美商戴諾治療公司 衣殼多肽及其使用方法(二)
WO2025090631A1 (en) * 2023-10-23 2025-05-01 The Children's Hospital Of Philadelphia Aav vectors for delivery of apoe2
WO2025090598A1 (en) * 2023-10-23 2025-05-01 The Children's Hospital Of Philadelphia Aav vectors for treatment of cln2 disease
WO2025106874A1 (en) * 2023-11-15 2025-05-22 Genzyme Corporation Methods of treating neurodegenerative disorders
US20250152747A1 (en) 2023-11-15 2025-05-15 Genzyme Corporation Methods of treating gaucher disease and gba-parkinson’s disease
TW202545971A (zh) 2024-02-08 2025-12-01 美商戴諾治療公司 殼體多肽及其使用方法
WO2025213097A1 (en) * 2024-04-05 2025-10-09 The Children's Hospital Of Philadelphia Novel gene therapy constructs for stxbp1 haploinsufficiency
WO2025231406A1 (en) * 2024-05-02 2025-11-06 The Children's Hospital Of Philadelphia Methods to increase transduction of ependyma cells in brain
WO2026064442A2 (en) 2024-09-18 2026-03-26 Dyno Therapeutics, Inc. Capsid polypeptides and methods of use thereof
CN120242044B (zh) * 2025-06-06 2025-09-23 昆明理工大学 一种靶向性的药物递送载体及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040031072A1 (en) * 1999-05-06 2004-02-12 La Rosa Thomas J. Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement
DK2359869T3 (en) * 2001-12-17 2019-04-15 Univ Pennsylvania Sequences of adeno-associated virus (AAV) serotype 8, vectors containing these, and uses thereof
US9585971B2 (en) * 2013-09-13 2017-03-07 California Institute Of Technology Recombinant AAV capsid protein
DE102014207498A1 (de) * 2014-04-17 2015-10-22 Universitätsklinikum Hamburg-Eppendorf Viraler Vektor für den zielgerichteten Gentransfer in Gehirn und Rückenmark
KR102423442B1 (ko) * 2015-12-11 2022-07-20 캘리포니아 인스티튜트 오브 테크놀로지 아데노-관련 바이러스를 지시하기 위한 타겟팅 펩타이드
BR112019016769A2 (pt) * 2017-02-15 2020-05-26 The University Of North Carolina At Chapel Hill Métodos e composições para transferência genética através da vasculatura
MX2019013528A (es) * 2017-05-12 2020-07-14 The Children´S Hospital Of Philadelphia Variantes de sulfamidasa (sgsh) y vectores, composiciones, metodos y usos para tratar la mucopolisacaridosis tipo iiia (mps iiia).
SG11202002276VA (en) * 2017-09-20 2020-04-29 4D Molecular Therapeutics Inc Adeno-associated virus variant capsids and methods of use thereof
US20200263199A1 (en) * 2017-09-29 2020-08-20 Voyager Therapeutics, Inc. Rescue of central and peripheral neurological phenotype of friedreich's ataxia by intravenous delivery
WO2019113538A2 (en) * 2017-12-07 2019-06-13 California Institute Of Technology Methods and systems for noninvasive control of brain cells and related vectors and compositions
TW202015742A (zh) * 2018-05-15 2020-05-01 美商航海家醫療公司 投遞腺相關病毒(aav)之組成物和方法
CN112703198B (zh) * 2018-07-11 2025-05-30 布里格姆妇女医院 用于跨血脑屏障递送试剂的方法和组合物

Similar Documents

Publication Publication Date Title
BR112023005462A2 (https=)
JP2023503455A5 (https=)
BR112023012656A2 (https=)
BR112021014123A2 (https=)
BR112023009656A2 (https=)
BR112022009896A2 (https=)
BR112021017747A2 (https=)
BR112022024743A2 (https=)
BR112022026905A2 (https=)
BR112023011738A2 (https=)
BR112023004146A2 (https=)
BR112023006729A2 (https=)
BR102021018859A2 (https=)
BR112023016292A2 (https=)
BR112023011610A2 (https=)
BR112023011539A2 (https=)
BR112023008976A2 (https=)
BR102021020147A2 (https=)
BR102021018926A2 (https=)
BR102021018167A2 (https=)
BR102021017576A2 (https=)
BR102021016837A2 (https=)
BR102021015247A2 (https=)
BR102021015220A2 (https=)
BR102021014044A2 (https=)