JP2023183417A5 - - Google Patents
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- Publication number
- JP2023183417A5 JP2023183417A5 JP2023159322A JP2023159322A JP2023183417A5 JP 2023183417 A5 JP2023183417 A5 JP 2023183417A5 JP 2023159322 A JP2023159322 A JP 2023159322A JP 2023159322 A JP2023159322 A JP 2023159322A JP 2023183417 A5 JP2023183417 A5 JP 2023183417A5
- Authority
- JP
- Japan
- Prior art keywords
- splice site
- codon
- donor splice
- antibody
- unpaired
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19183171 | 2019-06-28 | ||
| EP19183171.8 | 2019-06-28 | ||
| PCT/EP2020/067770 WO2020260431A1 (en) | 2019-06-28 | 2020-06-25 | Method for the production of an antibody |
| JP2021577247A JP7511591B2 (ja) | 2019-06-28 | 2020-06-25 | 抗体の製造方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021577247A Division JP7511591B2 (ja) | 2019-06-28 | 2020-06-25 | 抗体の製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023183417A JP2023183417A (ja) | 2023-12-27 |
| JP2023183417A5 true JP2023183417A5 (https=) | 2024-07-18 |
| JP7835713B2 JP7835713B2 (ja) | 2026-03-25 |
Family
ID=67253661
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021577247A Active JP7511591B2 (ja) | 2019-06-28 | 2020-06-25 | 抗体の製造方法 |
| JP2023159322A Active JP7835713B2 (ja) | 2019-06-28 | 2023-09-25 | 抗体の製造方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021577247A Active JP7511591B2 (ja) | 2019-06-28 | 2020-06-25 | 抗体の製造方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220220500A1 (https=) |
| EP (1) | EP3990484A1 (https=) |
| JP (2) | JP7511591B2 (https=) |
| KR (1) | KR102900433B1 (https=) |
| CN (1) | CN113993888B (https=) |
| AU (1) | AU2020304841B2 (https=) |
| BR (1) | BR112021025806A2 (https=) |
| CA (1) | CA3143803A1 (https=) |
| IL (1) | IL289210A (https=) |
| MX (1) | MX2021015193A (https=) |
| WO (1) | WO2020260431A1 (https=) |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| WO1988007089A1 (en) | 1987-03-18 | 1988-09-22 | Medical Research Council | Altered antibodies |
| US5010182A (en) | 1987-07-28 | 1991-04-23 | Chiron Corporation | DNA constructs containing a Kluyveromyces alpha factor leader sequence for directing secretion of heterologous polypeptides |
| AU4005289A (en) | 1988-08-25 | 1990-03-01 | Smithkline Beecham Corporation | Recombinant saccharomyces |
| US5082767A (en) | 1989-02-27 | 1992-01-21 | Hatfield G Wesley | Codon pair utilization |
| US5959177A (en) | 1989-10-27 | 1999-09-28 | The Scripps Research Institute | Transgenic plants expressing assembled secretory antibodies |
| US5795737A (en) | 1994-09-19 | 1998-08-18 | The General Hospital Corporation | High level expression of proteins |
| US6040498A (en) | 1998-08-11 | 2000-03-21 | North Caroline State University | Genetically engineered duckweed |
| CN100427603C (zh) | 1999-10-04 | 2008-10-22 | 麦迪卡格公司 | 调控外源基因转录的方法 |
| US7125978B1 (en) | 1999-10-04 | 2006-10-24 | Medicago Inc. | Promoter for regulating expression of foreign genes |
| JP2006238894A (ja) * | 2000-02-15 | 2006-09-14 | Amgen Inc | 線維芽細胞成長因子−２３分子およびその使用 |
| ATE318908T1 (de) | 2000-05-18 | 2006-03-15 | Geneart Gmbh | Synthetische gene für gagpol und deren verwendungen |
| US7879540B1 (en) | 2000-08-24 | 2011-02-01 | Promega Corporation | Synthetic nucleic acid molecule compositions and methods of preparation |
| AU2003206684A1 (en) | 2002-02-20 | 2003-09-09 | Novozymes A/S | Plant polypeptide production |
| US20040005600A1 (en) | 2002-04-01 | 2004-01-08 | Evelina Angov | Method of designing synthetic nucleic acid sequences for optimal protein expression in a host cell |
| US20060024670A1 (en) | 2004-05-18 | 2006-02-02 | Luke Catherine J | Influenza virus vaccine composition and methods of use |
| EA200700751A1 (ru) * | 2004-10-05 | 2008-06-30 | Элан Фарма Интернэшнл Лимитед | Способы и композиции для улучшения продуцирования рекомбинантного белка |
| EP2021489A2 (en) | 2006-05-30 | 2009-02-11 | Dow Global Technologies Inc. | Codon optimization method |
| DK2423315T3 (en) | 2006-06-29 | 2015-04-13 | Dsm Ip Assets Bv | A method for obtaining enhanced polypeptide expression |
| LT2167540T (lt) * | 2007-06-29 | 2018-04-25 | F. Hoffmann-La Roche Ag | Sunkioji grandinė mutantė, pagerinanti imunoglobulino gamybą |
| US7947495B2 (en) * | 2007-11-01 | 2011-05-24 | Abbott Biotherapeutics Corp. | Immunoglobulin display vectors |
| AU2009314111A1 (en) * | 2008-11-12 | 2010-05-20 | Merck Sharp & Dohme Corp. | BetaGI-IgG intron for enhanced anti-IGF1 R expression |
| US20100303776A1 (en) * | 2009-04-16 | 2010-12-02 | The University Of North Carolina At Chapel Hill | Methods and compositions for regulated expression of multiple nucleic acids |
| KR20130013435A (ko) | 2011-07-28 | 2013-02-06 | 차의과학대학교 산학협력단 | 태반-유래 줄기세포의 증식방법 |
| CN109810188A (zh) * | 2011-12-21 | 2019-05-28 | 弗·哈夫曼-拉罗切有限公司 | 用于克隆和表达关联抗体可变区基因区段的快速方法 |
| EP2794878B1 (en) * | 2011-12-22 | 2020-03-18 | F.Hoffmann-La Roche Ag | Expression vector organization, novel production cell generation methods and their use for the recombinant production of polypeptides |
| GB2502127A (en) * | 2012-05-17 | 2013-11-20 | Kymab Ltd | Multivalent antibodies and in vivo methods for their production |
| JP6224077B2 (ja) * | 2012-04-17 | 2017-11-01 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 改変された核酸を用いてポリペプチドを発現させるための方法 |
| SG10201913396RA (en) * | 2014-02-28 | 2020-03-30 | Ichnos Sciences SA | Expression constructs and methods for selecting host cells expressing polypeptides |
| KR20180018659A (ko) * | 2015-06-08 | 2018-02-21 | 코닝 인코포레이티드 | 전달이 없는 마이크로엘이디 디스플레이 |
-
2020
- 2020-06-25 EP EP20734039.9A patent/EP3990484A1/en active Pending
- 2020-06-25 AU AU2020304841A patent/AU2020304841B2/en active Active
- 2020-06-25 KR KR1020227002552A patent/KR102900433B1/ko active Active
- 2020-06-25 JP JP2021577247A patent/JP7511591B2/ja active Active
- 2020-06-25 MX MX2021015193A patent/MX2021015193A/es unknown
- 2020-06-25 BR BR112021025806A patent/BR112021025806A2/pt unknown
- 2020-06-25 CN CN202080045482.6A patent/CN113993888B/zh active Active
- 2020-06-25 WO PCT/EP2020/067770 patent/WO2020260431A1/en not_active Ceased
- 2020-06-25 CA CA3143803A patent/CA3143803A1/en active Pending
-
2021
- 2021-12-21 IL IL289210A patent/IL289210A/en unknown
- 2021-12-22 US US17/559,934 patent/US20220220500A1/en active Pending
-
2023
- 2023-09-25 JP JP2023159322A patent/JP7835713B2/ja active Active
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