JP2023076465A5 - - Google Patents
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- Publication number
- JP2023076465A5 JP2023076465A5 JP2023034704A JP2023034704A JP2023076465A5 JP 2023076465 A5 JP2023076465 A5 JP 2023076465A5 JP 2023034704 A JP2023034704 A JP 2023034704A JP 2023034704 A JP2023034704 A JP 2023034704A JP 2023076465 A5 JP2023076465 A5 JP 2023076465A5
- Authority
- JP
- Japan
- Prior art keywords
- formulation
- dexmedetomidine
- minutes
- subject
- insomnia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000009472 formulation Methods 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- HRLIOXLXPOHXTA-NSHDSACASA-N dexmedetomidine Chemical compound C1([C@@H](C)C=2C(=C(C)C=CC=2)C)=CN=C[N]1 HRLIOXLXPOHXTA-NSHDSACASA-N 0.000 claims 2
- 229960004253 dexmedetomidine Drugs 0.000 claims 2
- 208000019116 sleep disease Diseases 0.000 claims 2
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 claims 1
- 206010022437 insomnia Diseases 0.000 claims 1
- 210000002200 mouth mucosa Anatomy 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 208000020685 sleep-wake disease Diseases 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025030902A JP2025092508A (ja) | 2014-10-15 | 2025-02-28 | デクスメデトミジン製剤を使用する睡眠障害の予防または治療 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462064205P | 2014-10-15 | 2014-10-15 | |
| US62/064,205 | 2014-10-15 | ||
| JP2021025810A JP2021080276A (ja) | 2014-10-15 | 2021-02-22 | デクスメデトミジン製剤を使用する睡眠障害の予防または治療 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021025810A Division JP2021080276A (ja) | 2014-10-15 | 2021-02-22 | デクスメデトミジン製剤を使用する睡眠障害の予防または治療 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025030902A Division JP2025092508A (ja) | 2014-10-15 | 2025-02-28 | デクスメデトミジン製剤を使用する睡眠障害の予防または治療 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023076465A JP2023076465A (ja) | 2023-06-01 |
| JP2023076465A5 true JP2023076465A5 (https=) | 2024-03-25 |
Family
ID=55747372
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017520539A Pending JP2017534613A (ja) | 2014-10-15 | 2015-10-15 | デクスメデトミジン製剤を使用する睡眠障害の予防または治療 |
| JP2021025810A Pending JP2021080276A (ja) | 2014-10-15 | 2021-02-22 | デクスメデトミジン製剤を使用する睡眠障害の予防または治療 |
| JP2023034704A Pending JP2023076465A (ja) | 2014-10-15 | 2023-03-07 | デクスメデトミジン製剤を使用する睡眠障害の予防または治療 |
| JP2025030902A Pending JP2025092508A (ja) | 2014-10-15 | 2025-02-28 | デクスメデトミジン製剤を使用する睡眠障害の予防または治療 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017520539A Pending JP2017534613A (ja) | 2014-10-15 | 2015-10-15 | デクスメデトミジン製剤を使用する睡眠障害の予防または治療 |
| JP2021025810A Pending JP2021080276A (ja) | 2014-10-15 | 2021-02-22 | デクスメデトミジン製剤を使用する睡眠障害の予防または治療 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025030902A Pending JP2025092508A (ja) | 2014-10-15 | 2025-02-28 | デクスメデトミジン製剤を使用する睡眠障害の予防または治療 |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US20170239221A1 (https=) |
| EP (1) | EP3206685B1 (https=) |
| JP (4) | JP2017534613A (https=) |
| MA (1) | MA41689A (https=) |
| WO (1) | WO2016061413A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102793584B1 (ko) * | 2016-12-31 | 2025-04-09 | 바이오엑셀 테라퓨틱스 인코포레이티드 | 불안의 치료를 위한 설하 덱스메데토미딘의 용도 |
| PL3813802T3 (pl) | 2018-06-27 | 2025-04-22 | Bioxcel Therapeutics, Inc. | Formulacje błony zawierające deksmedetomidynę i sposoby ich wytwarzania |
| EP3999058A4 (en) * | 2019-07-19 | 2023-05-03 | Bioxcel Therapeutics, Inc. | NON-SEDATIVE DEXMEDETOMIDINE-BASED TREATMENT REGIMEN |
| CN118948739A (zh) * | 2020-06-08 | 2024-11-15 | 四川普锐特药业有限公司 | 右美托咪定滴鼻剂或鼻喷剂在助眠药物制备中的应用 |
| JP2024511394A (ja) | 2021-03-19 | 2024-03-13 | オリオン コーポレーション | タシピミジン製剤およびその使用 |
| CN115197149B (zh) * | 2021-04-02 | 2023-09-22 | 四川大学华西医院 | 一种5-苄基咪唑类化合物及其制备方法和用途 |
| EP4364729A4 (en) * | 2021-08-23 | 2024-11-27 | Yichang Humanwell Pharmaceutical Co., Ltd. | TRANSDERMAL COMPOSITION OF DEXMEDETOMIDINE, TRANSDERMAL PATCH AND METHOD OF PREPARATION AND USE THEREOF |
| IL318007A (en) | 2022-07-27 | 2025-02-01 | Universit?T Z?Rich | Dexmedetocidin for the treatment of sleep disorders |
| US11806334B1 (en) | 2023-01-12 | 2023-11-07 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
| KR102853305B1 (ko) * | 2023-05-25 | 2025-09-01 | 가톨릭대학교 산학협력단 | 상추 추출물 및 대추 추출물을 유효성분을 함유하는 불면증 해소용 구강 붕해 필름 조성물 |
| CN117771220B (zh) * | 2024-02-28 | 2024-05-28 | 山东第二医科大学 | 一种右美托咪定中药多糖口溶膜剂及其制备方法和应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7632517B2 (en) * | 1997-10-01 | 2009-12-15 | Novadel Pharma Inc. | Buccal, polar and non-polar spray containing zolpidem |
| WO2002089794A1 (en) * | 2001-05-07 | 2002-11-14 | Universite Catholique De Louvain | Method for treating neuropathic pain and pharmaceutical preparation therefor |
| US20050222270A1 (en) * | 2004-02-26 | 2005-10-06 | Olney John W | Prolonged administration of NMDA antagonist drug and safener drug to create improved stable neural homeostasis |
| CA2580694A1 (en) * | 2004-09-23 | 2006-03-30 | Alexander Michalow | Methods for regulating neurotransmitter systems by inducing counteradaptations |
| US7378508B2 (en) * | 2007-01-22 | 2008-05-27 | Optimer Pharmaceuticals, Inc. | Polymorphic crystalline forms of tiacumicin B |
| US20090076156A1 (en) * | 2005-07-18 | 2009-03-19 | Masud Husain | Use of a noradrenergic agonist, e.g. guanfacine, for the treatment of cognitive disorders |
| PT1986642E (pt) * | 2006-02-13 | 2014-01-30 | Orient Pharma Samoa Co Ltd | Combinação de agonista do receptor alfa-2 (clonidina) e um agente antimuscarínico (oxibutinina) para o tratamento de sialorreia |
| WO2008091592A1 (en) * | 2007-01-22 | 2008-07-31 | Targacept, Inc. | Intranasal, buccal, and sublingual administration of metanicotine analogs |
| CN101801346A (zh) * | 2007-05-10 | 2010-08-11 | 诺瓦德尔药品公司 | 抗失眠症组合物及方法 |
| PE20091084A1 (es) * | 2007-12-07 | 2009-07-23 | Schering Plough Healthcare | Formulaciones farmaceuticas de fenilefrina y composiciones para absorcion transmucosal |
| US20100196286A1 (en) * | 2008-12-01 | 2010-08-05 | Armer Thomas A | Inhalation delivery methods and devices |
| RU2572692C2 (ru) * | 2009-05-15 | 2016-01-20 | Рекро Фарма, Инк. | Сублингвальные композиции дексмедетомидина и способы их применения |
| AU2011204315A1 (en) * | 2010-01-08 | 2012-08-02 | Recro Pharma, Inc. | Topical transdermal dexmedetomidine compositions and methods of use thereof |
| US8241661B1 (en) * | 2011-06-24 | 2012-08-14 | Fuisz Richard C | Biocompatible film with variable cross-sectional properties |
| US20130116215A1 (en) * | 2011-10-28 | 2013-05-09 | Mireia Coma | Combination therapies for treating neurological disorders |
| AU2012352528B9 (en) * | 2011-12-11 | 2017-11-02 | Baudax Bio, Inc. | Intranasal dexmedetomidine compositions and methods of use thereof |
| CA2924233C (en) * | 2013-10-07 | 2018-10-23 | Teikoku Pharma Usa, Inc. | Methods and compositions for treating attention deficit hyperactivity disorder, anxiety and insomnia using dexmedetomidine transdermal compositions |
-
2015
- 2015-10-14 MA MA041689A patent/MA41689A/fr unknown
- 2015-10-15 WO PCT/US2015/055828 patent/WO2016061413A1/en not_active Ceased
- 2015-10-15 EP EP15850725.1A patent/EP3206685B1/en active Active
- 2015-10-15 US US15/519,463 patent/US20170239221A1/en not_active Abandoned
- 2015-10-15 JP JP2017520539A patent/JP2017534613A/ja active Pending
-
2021
- 2021-02-22 JP JP2021025810A patent/JP2021080276A/ja active Pending
-
2023
- 2023-03-07 JP JP2023034704A patent/JP2023076465A/ja active Pending
- 2023-09-05 US US18/242,236 patent/US20230414572A1/en not_active Abandoned
-
2024
- 2024-04-12 US US18/634,242 patent/US20250099430A1/en active Pending
-
2025
- 2025-02-28 JP JP2025030902A patent/JP2025092508A/ja active Pending
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