JP2023041862A5 - - Google Patents
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- Publication number
- JP2023041862A5 JP2023041862A5 JP2023014583A JP2023014583A JP2023041862A5 JP 2023041862 A5 JP2023041862 A5 JP 2023041862A5 JP 2023014583 A JP2023014583 A JP 2023014583A JP 2023014583 A JP2023014583 A JP 2023014583A JP 2023041862 A5 JP2023041862 A5 JP 2023041862A5
- Authority
- JP
- Japan
- Prior art keywords
- dextromethorphan
- person
- bupropion
- administered
- twice daily
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- MKXZASYAUGDDCJ-SZMVWBNQSA-N LSM-2525 Chemical compound C1CCC[C@H]2[C@@]3([H])N(C)CC[C@]21C1=CC(OC)=CC=C1C3 MKXZASYAUGDDCJ-SZMVWBNQSA-N 0.000 claims 20
- 229960001985 dextromethorphan Drugs 0.000 claims 20
- 229960001058 bupropion Drugs 0.000 claims 18
- SNPPWIUOZRMYNY-UHFFFAOYSA-N bupropion Chemical compound CC(C)(C)NC(C)C(=O)C1=CC=CC(Cl)=C1 SNPPWIUOZRMYNY-UHFFFAOYSA-N 0.000 claims 18
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 claims 4
- 229960002715 nicotine Drugs 0.000 claims 4
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 claims 4
- 206010057852 Nicotine dependence Diseases 0.000 claims 3
- 208000025569 Tobacco Use disease Diseases 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 2
- IKBZAUYPBWFMDI-UHFFFAOYSA-N 5-bromo-4-methoxy-7-methyl-2,3-dihydro-1h-indene Chemical compound C1=C(Br)C(OC)=C2CCCC2=C1C IKBZAUYPBWFMDI-UHFFFAOYSA-N 0.000 claims 1
- YZCKVEUIGOORGS-OUBTZVSYSA-N Deuterium Chemical compound [2H] YZCKVEUIGOORGS-OUBTZVSYSA-N 0.000 claims 1
- 229960004367 bupropion hydrochloride Drugs 0.000 claims 1
- 229910052805 deuterium Inorganic materials 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025077089A JP2025105965A (ja) | 2014-11-21 | 2025-05-07 | ブプロピオンおよびデキストロメトルファンを含む剤形 |
Applications Claiming Priority (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/550,618 | 2014-11-21 | ||
| US14/550,618 US9198905B2 (en) | 2013-11-05 | 2014-11-21 | Compositions and methods for reducing dextrorphan plasma levels and related pharmacodynamic effects |
| US14/554,988 US9205083B2 (en) | 2013-11-05 | 2014-11-26 | Compositions and methods comprising erythrohydroxybupropion and related compounds for improving the efficacy of dextromethorphan |
| US14/554,947 US20150126542A1 (en) | 2013-11-05 | 2014-11-26 | Compositions and Methods for Increasing the Metabolic Lifetime of Dextromethorphan and Related Pharmacodynamic Effects |
| US14/554,947 | 2014-11-26 | ||
| US14/555,085 | 2014-11-26 | ||
| US14/554,988 | 2014-11-26 | ||
| US14/555,085 US9238032B2 (en) | 2013-11-05 | 2014-11-26 | Compositions and methods comprising bupropion or related compounds for sustained delivery of dextromethorphan |
| US14/602,177 US9402843B2 (en) | 2013-11-05 | 2015-01-21 | Compositions and methods of using threohydroxybupropion for therapeutic purposes |
| US14/602,177 | 2015-01-21 | ||
| US14/604,397 US9168234B2 (en) | 2013-11-05 | 2015-01-23 | Bupropion as a modulator of drug activity |
| US14/604,397 | 2015-01-23 | ||
| US14/617,624 US9486450B2 (en) | 2013-11-05 | 2015-02-09 | Hydroxybupropion and related compounds as modulators of drug plasma levels |
| US14/617,624 | 2015-02-09 | ||
| US14/628,062 | 2015-02-20 | ||
| US14/628,062 US9402844B2 (en) | 2013-11-05 | 2015-02-20 | Methods of modulating drug plasma levels using erythrohydroxybupropion |
| JP2021016211A JP7226839B2 (ja) | 2014-11-21 | 2021-02-04 | ブプロピオンおよびデキストロメトルファンを含む組成物 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021016211A Division JP7226839B2 (ja) | 2014-11-21 | 2021-02-04 | ブプロピオンおよびデキストロメトルファンを含む組成物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025077089A Division JP2025105965A (ja) | 2014-11-21 | 2025-05-07 | ブプロピオンおよびデキストロメトルファンを含む剤形 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023041862A JP2023041862A (ja) | 2023-03-24 |
| JP2023041862A5 true JP2023041862A5 (https=) | 2023-06-01 |
Family
ID=56014366
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017527254A Active JP6602863B2 (ja) | 2014-11-21 | 2015-05-01 | ブプロピオンまたは関連組成物およびデキストロメトルファンを含む医薬組成物 |
| JP2019185676A Active JP6842129B2 (ja) | 2014-11-21 | 2019-10-09 | ブプロピオンまたは関連組成物およびデキストロメトルファンを含む組成物および方法 |
| JP2021016211A Active JP7226839B2 (ja) | 2014-11-21 | 2021-02-04 | ブプロピオンおよびデキストロメトルファンを含む組成物 |
| JP2023014583A Pending JP2023041862A (ja) | 2014-11-21 | 2023-02-02 | ニコチン中毒の治療が必要な人の治療のための医薬品の製造における、ブプロピオンまたはその薬学的に許容される塩と、デキストロメトルファンまたはその薬学的に許容される塩との組み合わせの使用 |
| JP2025077089A Pending JP2025105965A (ja) | 2014-11-21 | 2025-05-07 | ブプロピオンおよびデキストロメトルファンを含む剤形 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017527254A Active JP6602863B2 (ja) | 2014-11-21 | 2015-05-01 | ブプロピオンまたは関連組成物およびデキストロメトルファンを含む医薬組成物 |
| JP2019185676A Active JP6842129B2 (ja) | 2014-11-21 | 2019-10-09 | ブプロピオンまたは関連組成物およびデキストロメトルファンを含む組成物および方法 |
| JP2021016211A Active JP7226839B2 (ja) | 2014-11-21 | 2021-02-04 | ブプロピオンおよびデキストロメトルファンを含む組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025077089A Pending JP2025105965A (ja) | 2014-11-21 | 2025-05-07 | ブプロピオンおよびデキストロメトルファンを含む剤形 |
Country Status (22)
| Country | Link |
|---|---|
| EP (2) | EP3220909B2 (https=) |
| JP (5) | JP6602863B2 (https=) |
| KR (7) | KR101931896B1 (https=) |
| CN (2) | CN111297860A (https=) |
| AU (4) | AU2015350559C1 (https=) |
| CA (3) | CA3232022A1 (https=) |
| CY (1) | CY1123571T1 (https=) |
| DK (1) | DK3220909T3 (https=) |
| ES (1) | ES2835304T3 (https=) |
| HR (1) | HRP20201855T1 (https=) |
| HU (1) | HUE052609T2 (https=) |
| IL (4) | IL297349B2 (https=) |
| LT (1) | LT3220909T (https=) |
| MX (3) | MX2017006653A (https=) |
| MY (1) | MY189466A (https=) |
| PL (1) | PL3220909T3 (https=) |
| PT (1) | PT3220909T (https=) |
| RS (1) | RS61113B1 (https=) |
| SG (2) | SG11201704066VA (https=) |
| SI (1) | SI3220909T1 (https=) |
| SM (1) | SMT202000639T1 (https=) |
| WO (1) | WO2016081027A1 (https=) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11576909B2 (en) | 2013-11-05 | 2023-02-14 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11229640B2 (en) | 2013-11-05 | 2022-01-25 | Antecip Bioventures Ii Llc | Combination of dextromethorphan and bupropion for treating depression |
| US11576877B2 (en) | 2013-11-05 | 2023-02-14 | Antecip Bioventures Ii Llc | Bupropion as modulator of drug activity |
| US11419867B2 (en) | 2013-11-05 | 2022-08-23 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11291665B2 (en) | 2013-11-05 | 2022-04-05 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11590124B2 (en) | 2013-11-05 | 2023-02-28 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11344544B2 (en) | 2013-11-05 | 2022-05-31 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11357744B2 (en) | 2013-11-05 | 2022-06-14 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11524007B2 (en) | 2013-11-05 | 2022-12-13 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11285118B2 (en) | 2013-11-05 | 2022-03-29 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11534414B2 (en) | 2013-11-05 | 2022-12-27 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11497721B2 (en) | 2013-11-05 | 2022-11-15 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11426370B2 (en) | 2013-11-05 | 2022-08-30 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11596627B2 (en) | 2013-11-05 | 2023-03-07 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11382874B2 (en) | 2013-11-05 | 2022-07-12 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11617728B2 (en) | 2013-11-05 | 2023-04-04 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US12109178B2 (en) | 2013-11-05 | 2024-10-08 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US12194006B2 (en) | 2013-11-05 | 2025-01-14 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11617747B2 (en) | 2013-11-05 | 2023-04-04 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11517543B2 (en) | 2013-11-05 | 2022-12-06 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11571399B2 (en) | 2013-11-05 | 2023-02-07 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11433067B2 (en) | 2013-11-05 | 2022-09-06 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11969421B2 (en) | 2013-11-05 | 2024-04-30 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11364233B2 (en) | 2013-11-05 | 2022-06-21 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11207281B2 (en) | 2013-11-05 | 2021-12-28 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11478468B2 (en) | 2013-11-05 | 2022-10-25 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11191739B2 (en) | 2013-11-05 | 2021-12-07 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11571417B2 (en) | 2013-11-05 | 2023-02-07 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11541021B2 (en) | 2013-11-05 | 2023-01-03 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US20220233470A1 (en) | 2013-11-05 | 2022-07-28 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11439636B1 (en) | 2013-11-05 | 2022-09-13 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11426401B2 (en) | 2013-11-05 | 2022-08-30 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11197839B2 (en) | 2013-11-05 | 2021-12-14 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11298352B2 (en) | 2013-11-05 | 2022-04-12 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11510918B2 (en) | 2013-11-05 | 2022-11-29 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11541048B2 (en) | 2013-11-05 | 2023-01-03 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| US11298351B2 (en) | 2013-11-05 | 2022-04-12 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| CA3232022A1 (en) * | 2014-11-21 | 2016-05-26 | Antecip Bioventures Ii Llc | Methods of modulating drug plasma levels using erythrohydroxybupropion |
| US12569479B2 (en) | 2016-05-25 | 2026-03-10 | Antecip Bioventures Ii Llc | Bupropion as a modulator of drug activity |
| SMT202600055T1 (it) * | 2019-01-07 | 2026-03-09 | Antecip Bioventures Ii Llc | Combinazione di destrometorfano e bupropione per trattare la depressione in pazienti asiatici |
| US12433884B2 (en) | 2020-06-05 | 2025-10-07 | Antecip Bioventures Ii Llc | Compounds and combinations thereof for treating neurological and psychiatric conditions |
| US12472156B2 (en) | 2020-06-05 | 2025-11-18 | Antecip Bioventures Ii Llc | Compounds and combinations thereof for treating neurological and psychiatric conditions |
| US20250073188A1 (en) | 2020-06-05 | 2025-03-06 | Antecip Bioventures Ii Llc | Compounds and combinations thereof for treating neurological and psychiatric conditions |
| EP4183391A4 (en) * | 2020-07-20 | 2024-04-17 | Shenzhen Salubris Pharmaceuticals Co., Ltd. | PHARMACEUTICAL COMPOSITION AND ITS USE |
| US11717518B1 (en) | 2022-06-30 | 2023-08-08 | Antecip Bioventures Ii Llc | Bupropion dosage forms with reduced food and alcohol dosing effects |
| US11730706B1 (en) | 2022-07-07 | 2023-08-22 | Antecip Bioventures Ii Llc | Treatment of depression in certain patient populations |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5350756A (en) * | 1991-06-17 | 1994-09-27 | Smith Richard A | Use of a cytochrome oxidase inhibitor to increase the cough-suppressing activity of dextromorphan |
| EP1986639A4 (en) * | 2006-02-03 | 2010-04-28 | Avanir Pharmaceuticals | PHARMACEUTICAL COMPOSITIONS OF DEXTROMETHORPHANE AND CHINIDINE FOR THE TREATMENT OF DEPRESSION, FEAR STATES AND NEURODEEGENERATIVE DISEASES |
| WO2009006194A1 (en) | 2007-06-28 | 2009-01-08 | Avanir Pharmaceuticals | Pharmaceutical compositions for the treatment of involuntary emotional expression disorder |
| WO2012118562A1 (en) | 2011-03-02 | 2012-09-07 | Rhine Pharmaceuticals, Llc | Compositions and methods for treating depression, adhd and other central nervous system disorders employing novel bupropion compounds, and methods for production and use of novel bupropion compounds and formulations |
| US20130274282A1 (en) * | 2012-04-16 | 2013-10-17 | Herriot Tabuteau | Compositions and methods comprising celecoxib or related compounds and dextromethorphan |
| MY179696A (en) | 2013-11-05 | 2020-11-11 | Antecip Bioventures Ii Llc | Compositions and methods comprising bupropion or related compounds and dextromethorphan |
| US9402843B2 (en) | 2013-11-05 | 2016-08-02 | Antecip Bioventures Ii Llc | Compositions and methods of using threohydroxybupropion for therapeutic purposes |
| US9198905B2 (en) | 2013-11-05 | 2015-12-01 | Antecip Bioventures Ii Llc | Compositions and methods for reducing dextrorphan plasma levels and related pharmacodynamic effects |
| CA3232022A1 (en) | 2014-11-21 | 2016-05-26 | Antecip Bioventures Ii Llc | Methods of modulating drug plasma levels using erythrohydroxybupropion |
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2015
- 2015-05-01 CA CA3232022A patent/CA3232022A1/en active Pending
- 2015-05-01 MY MYPI2017701828A patent/MY189466A/en unknown
- 2015-05-01 SG SG11201704066VA patent/SG11201704066VA/en unknown
- 2015-05-01 IL IL297349A patent/IL297349B2/en unknown
- 2015-05-01 PT PT158611897T patent/PT3220909T/pt unknown
- 2015-05-01 WO PCT/US2015/028901 patent/WO2016081027A1/en not_active Ceased
- 2015-05-01 LT LTEP15861189.7T patent/LT3220909T/lt unknown
- 2015-05-01 HU HUE15861189A patent/HUE052609T2/hu unknown
- 2015-05-01 SI SI201531421T patent/SI3220909T1/sl unknown
- 2015-05-01 DK DK15861189.7T patent/DK3220909T3/da active
- 2015-05-01 ES ES15861189T patent/ES2835304T3/es active Active
- 2015-05-01 CN CN202010202397.8A patent/CN111297860A/zh active Pending
- 2015-05-01 CA CA2968371A patent/CA2968371C/en active Active
- 2015-05-01 IL IL280905A patent/IL280905B2/en unknown
- 2015-05-01 KR KR1020177017050A patent/KR101931896B1/ko active Active
- 2015-05-01 EP EP15861189.7A patent/EP3220909B2/en active Active
- 2015-05-01 CN CN201580074124.7A patent/CN107205998A/zh active Pending
- 2015-05-01 KR KR1020247005737A patent/KR102822654B1/ko active Active
- 2015-05-01 RS RS20201405A patent/RS61113B1/sr unknown
- 2015-05-01 EP EP20193845.3A patent/EP3763372A1/en active Pending
- 2015-05-01 IL IL314982A patent/IL314982A/en unknown
- 2015-05-01 JP JP2017527254A patent/JP6602863B2/ja active Active
- 2015-05-01 AU AU2015350559A patent/AU2015350559C1/en active Active
- 2015-05-01 CA CA3082645A patent/CA3082645C/en active Active
- 2015-05-01 MX MX2017006653A patent/MX2017006653A/es unknown
- 2015-05-01 HR HRP20201855TT patent/HRP20201855T1/hr unknown
- 2015-05-01 KR KR1020187036244A patent/KR102253986B1/ko active Active
- 2015-05-01 PL PL15861189T patent/PL3220909T3/pl unknown
- 2015-05-01 KR KR1020257019724A patent/KR20250092295A/ko active Pending
- 2015-05-01 SM SM20200639T patent/SMT202000639T1/it unknown
- 2015-05-01 MX MX2021001442A patent/MX2021001442A/es unknown
- 2015-05-01 KR KR1020227008513A patent/KR102524253B1/ko active Active
- 2015-05-01 KR KR1020217014289A patent/KR102376868B1/ko active Active
- 2015-05-01 KR KR1020237012943A patent/KR102640586B1/ko active Active
- 2015-05-02 SG SG10201911873XA patent/SG10201911873XA/en unknown
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2017
- 2017-05-19 MX MX2023000320A patent/MX2023000320A/es unknown
- 2017-05-21 IL IL252417A patent/IL252417B/en active IP Right Grant
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2019
- 2019-03-06 AU AU2019201548A patent/AU2019201548C1/en active Active
- 2019-10-09 JP JP2019185676A patent/JP6842129B2/ja active Active
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2020
- 2020-11-24 CY CY20201101110T patent/CY1123571T1/el unknown
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2021
- 2021-02-04 JP JP2021016211A patent/JP7226839B2/ja active Active
- 2021-02-15 AU AU2021200981A patent/AU2021200981B2/en active Active
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2023
- 2023-02-02 JP JP2023014583A patent/JP2023041862A/ja active Pending
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2024
- 2024-09-19 AU AU2024219871A patent/AU2024219871A1/en active Pending
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2025
- 2025-05-07 JP JP2025077089A patent/JP2025105965A/ja active Pending