JP2023038235A5 - - Google Patents
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- JP2023038235A5 JP2023038235A5 JP2023000803A JP2023000803A JP2023038235A5 JP 2023038235 A5 JP2023038235 A5 JP 2023038235A5 JP 2023000803 A JP2023000803 A JP 2023000803A JP 2023000803 A JP2023000803 A JP 2023000803A JP 2023038235 A5 JP2023038235 A5 JP 2023038235A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- pep
- attached
- gly
- carboxylic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762510370P | 2017-05-24 | 2017-05-24 | |
| US62/510,370 | 2017-05-24 | ||
| US201762557881P | 2017-09-13 | 2017-09-13 | |
| US62/557,881 | 2017-09-13 | ||
| JP2019565169A JP2020520981A (ja) | 2017-05-24 | 2018-05-23 | プロテアーゼのイメージング／検出のための化学発光プローブ |
| PCT/IL2018/050557 WO2018216012A1 (en) | 2017-05-24 | 2018-05-23 | Chemiluminescent probes for imaging/detection of proteases |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019565169A Division JP2020520981A (ja) | 2017-05-24 | 2018-05-23 | プロテアーゼのイメージング／検出のための化学発光プローブ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023038235A JP2023038235A (ja) | 2023-03-16 |
| JP2023038235A5 true JP2023038235A5 (enExample) | 2023-07-07 |
| JP7553615B2 JP7553615B2 (ja) | 2024-09-18 |
Family
ID=64396284
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019565169A Pending JP2020520981A (ja) | 2017-05-24 | 2018-05-23 | プロテアーゼのイメージング／検出のための化学発光プローブ |
| JP2023000803A Active JP7553615B2 (ja) | 2017-05-24 | 2023-01-06 | プロテアーゼのイメージング／検出のための化学発光プローブ |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019565169A Pending JP2020520981A (ja) | 2017-05-24 | 2018-05-23 | プロテアーゼのイメージング／検出のための化学発光プローブ |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US12173350B2 (enExample) |
| EP (1) | EP3630742B1 (enExample) |
| JP (2) | JP2020520981A (enExample) |
| CN (1) | CN110944985B (enExample) |
| ES (1) | ES2963606T3 (enExample) |
| PL (1) | PL3630742T3 (enExample) |
| WO (1) | WO2018216012A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112204020B (zh) * | 2018-05-25 | 2023-11-14 | 尼米斯技术公司 | 二氧杂环丁烷化合物及其用于检测微生物的用途 |
| WO2021165959A1 (en) * | 2020-02-19 | 2021-08-26 | Ramot At Tel-Aviv University Ltd. | Chemiluminescence probes for tuberculosis |
| EP4384515A4 (en) * | 2021-08-11 | 2025-09-03 | Univ Nanyang Tech | ULTRA-HIGH BRIGHTNESS CHEMILUMINESCENT PROBES FOR DETECTION AND IMAGING |
| CN114315791B (zh) * | 2021-12-22 | 2023-12-08 | 东南大学 | 用于实现手术导航和微小转移瘤成像的小分子化学发光探针及其制备方法和用途 |
| CN114380786B (zh) * | 2021-12-23 | 2023-03-24 | 苏州大学 | 基于氨基肽酶激活型化学发光探针及其在恶性肿瘤的活体检测与手术导航方面的应用 |
| CN114716407A (zh) * | 2022-03-16 | 2022-07-08 | 大连理工大学 | 一种检测泛酰巯基乙胺酶活性的化学发光探针、制备方法及其生物应用 |
| CN115819416B (zh) * | 2022-11-29 | 2024-06-25 | 遵义医科大学 | 一种用于检测和区分的多模态化学发光分子及其应用 |
| WO2024147125A1 (en) * | 2023-01-04 | 2024-07-11 | Ramot At Tel-Aviv University Ltd. | Cyclobutyl-substituted phenoxy-dioxetanes and uses thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6083486A (en) | 1998-05-14 | 2000-07-04 | The General Hospital Corporation | Intramolecularly-quenched near infrared fluorescent probes |
| KR100858640B1 (ko) * | 2000-03-29 | 2008-09-17 | 버텍스 파마슈티칼스 인코포레이티드 | 카스파제 억제용 카바메이트 화합물 |
| UA75093C2 (en) * | 2000-10-06 | 2006-03-15 | Dimensional Pharm Inc | Aminopyridinyl-,aminoguanidinyl-, and alkoxyguanidinesubstituted phenylsubstituted phenylacetamides as protease inhibitors |
| US9695251B2 (en) * | 2003-10-31 | 2017-07-04 | The Regents Of The University Of California | Activatable cell penetrating peptides with quenched fluorophores |
| US20100278745A1 (en) * | 2006-12-21 | 2010-11-04 | Norbert Lange | Compounds for fluorescence imaging |
| CN101772577A (zh) * | 2007-08-03 | 2010-07-07 | 塞诺菲-安万特股份有限公司 | 半胱天冬蛋白酶成像探针 |
| ES2658852T3 (es) * | 2008-01-18 | 2018-03-12 | Visen Medical, Inc. | Agentes de imaginología fluorescentes |
| CA2816041C (en) * | 2010-12-29 | 2019-01-08 | Arrowhead Research Corporation | In vivo polynucleotide delivery conjugates having enzyme sensitive linkages |
| EP2686385B1 (en) | 2011-03-15 | 2019-01-16 | Ramot at Tel Aviv University, Ltd. | Activatable fluorogenic compounds and uses thereof as near infrared probes |
| FR3022784B1 (fr) * | 2014-06-26 | 2017-09-08 | Ecole Normale Superieure Lyon | Sondes moleculaires activables hydrosolubles, intermediaires pour leur synthese et procedes de detection associes |
| CN108884386B (zh) * | 2016-01-26 | 2022-03-15 | 特拉维夫大学拉玛特有限公司 | 用于诊断和体内成像的化学发光探针 |
| CN112204020B (zh) * | 2018-05-25 | 2023-11-14 | 尼米斯技术公司 | 二氧杂环丁烷化合物及其用于检测微生物的用途 |
-
2018
- 2018-05-23 ES ES18804980T patent/ES2963606T3/es active Active
- 2018-05-23 PL PL18804980.3T patent/PL3630742T3/pl unknown
- 2018-05-23 US US16/616,356 patent/US12173350B2/en active Active
- 2018-05-23 EP EP18804980.3A patent/EP3630742B1/en active Active
- 2018-05-23 JP JP2019565169A patent/JP2020520981A/ja active Pending
- 2018-05-23 WO PCT/IL2018/050557 patent/WO2018216012A1/en not_active Ceased
- 2018-05-23 CN CN201880047726.7A patent/CN110944985B/zh active Active
-
2023
- 2023-01-06 JP JP2023000803A patent/JP7553615B2/ja active Active
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