JP2023026458A - 経腹膜蒸気焼灼システム及び方法 - Google Patents
経腹膜蒸気焼灼システム及び方法 Download PDFInfo
- Publication number
- JP2023026458A JP2023026458A JP2022196084A JP2022196084A JP2023026458A JP 2023026458 A JP2023026458 A JP 2023026458A JP 2022196084 A JP2022196084 A JP 2022196084A JP 2022196084 A JP2022196084 A JP 2022196084A JP 2023026458 A JP2023026458 A JP 2023026458A
- Authority
- JP
- Japan
- Prior art keywords
- electrode
- prostate
- tissue
- steam
- delivery device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title description 21
- 238000002679 ablation Methods 0.000 title description 3
- 210000002307 prostate Anatomy 0.000 claims abstract description 98
- 210000001519 tissue Anatomy 0.000 claims abstract description 90
- 239000012777 electrically insulating material Substances 0.000 claims abstract 2
- 230000010363 phase shift Effects 0.000 claims description 18
- 239000002131 composite material Substances 0.000 claims description 5
- 238000011282 treatment Methods 0.000 description 40
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 36
- 238000001816 cooling Methods 0.000 description 19
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 17
- 238000002560 therapeutic procedure Methods 0.000 description 16
- 239000011780 sodium chloride Substances 0.000 description 15
- 239000008223 sterile water Substances 0.000 description 13
- 208000000236 Prostatic Neoplasms Diseases 0.000 description 11
- 238000002604 ultrasonography Methods 0.000 description 11
- 206010060862 Prostate cancer Diseases 0.000 description 9
- 239000012530 fluid Substances 0.000 description 9
- 230000002093 peripheral effect Effects 0.000 description 9
- 210000003708 urethra Anatomy 0.000 description 9
- 239000004020 conductor Substances 0.000 description 8
- 239000003990 capacitor Substances 0.000 description 7
- 239000002775 capsule Substances 0.000 description 7
- 238000010438 heat treatment Methods 0.000 description 7
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 description 6
- 206010028980 Neoplasm Diseases 0.000 description 6
- 239000004642 Polyimide Substances 0.000 description 6
- 208000004403 Prostatic Hyperplasia Diseases 0.000 description 6
- 229910000831 Steel Inorganic materials 0.000 description 6
- 238000003384 imaging method Methods 0.000 description 6
- 229920001721 polyimide Polymers 0.000 description 6
- 239000010959 steel Substances 0.000 description 6
- 238000012285 ultrasound imaging Methods 0.000 description 6
- 238000004804 winding Methods 0.000 description 6
- 201000011510 cancer Diseases 0.000 description 5
- 230000000762 glandular Effects 0.000 description 5
- 238000009413 insulation Methods 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 238000005259 measurement Methods 0.000 description 5
- 210000004027 cell Anatomy 0.000 description 4
- 239000003989 dielectric material Substances 0.000 description 4
- 210000002640 perineum Anatomy 0.000 description 4
- 238000000926 separation method Methods 0.000 description 4
- 229920001774 Perfluoroether Polymers 0.000 description 3
- 230000004888 barrier function Effects 0.000 description 3
- 238000001574 biopsy Methods 0.000 description 3
- 210000000170 cell membrane Anatomy 0.000 description 3
- 230000001419 dependent effect Effects 0.000 description 3
- 229910001026 inconel Inorganic materials 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 230000007704 transition Effects 0.000 description 3
- 238000012800 visualization Methods 0.000 description 3
- 102000008186 Collagen Human genes 0.000 description 2
- 108010035532 Collagen Proteins 0.000 description 2
- 206010020880 Hypertrophy Diseases 0.000 description 2
- 230000005679 Peltier effect Effects 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 229920001436 collagen Polymers 0.000 description 2
- 230000001351 cycling effect Effects 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- 230000035699 permeability Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 102000006391 Ion Pumps Human genes 0.000 description 1
- 108010083687 Ion Pumps Proteins 0.000 description 1
- 240000007049 Juglans regia Species 0.000 description 1
- 235000009496 Juglans regia Nutrition 0.000 description 1
- 239000000232 Lipid Bilayer Substances 0.000 description 1
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 1
- 210000001789 adipocyte Anatomy 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 210000000436 anus Anatomy 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 229910001566 austenite Inorganic materials 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000012809 cooling fluid Substances 0.000 description 1
- 239000000498 cooling water Substances 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000003204 ejaculatory duct Anatomy 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 210000003722 extracellular fluid Anatomy 0.000 description 1
- 210000003195 fascia Anatomy 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 210000005260 human cell Anatomy 0.000 description 1
- 238000002847 impedance measurement Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 239000012212 insulator Substances 0.000 description 1
- 210000002977 intracellular fluid Anatomy 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 description 1
- 238000012153 long-term therapy Methods 0.000 description 1
- 229910000734 martensite Inorganic materials 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 238000013021 overheating Methods 0.000 description 1
- 230000002572 peristaltic effect Effects 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 238000002203 pretreatment Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000007674 radiofrequency ablation Methods 0.000 description 1
- 210000004927 skin cell Anatomy 0.000 description 1
- 210000002460 smooth muscle Anatomy 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000036962 time dependent Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 235000020234 walnut Nutrition 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/08—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by means of electrically-heated probes
- A61B18/082—Probes or electrodes therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/08—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by means of electrically-heated probes
- A61B18/10—Power sources therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/04—Protection of tissue around surgical sites against effects of non-mechanical surgery, e.g. laser surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
- A61B2018/00023—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids closed, i.e. without wound contact by the fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
- A61B2018/00029—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids open
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00047—Cooling or heating of the probe or tissue immediately surrounding the probe using Peltier effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00059—Material properties
- A61B2018/00071—Electrical conductivity
- A61B2018/00083—Electrical conductivity low, i.e. electrically insulating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00059—Material properties
- A61B2018/00089—Thermal conductivity
- A61B2018/00101—Thermal conductivity low, i.e. thermally insulating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00273—Anchoring means for temporary attachment of a device to tissue
- A61B2018/00279—Anchoring means for temporary attachment of a device to tissue deployable
- A61B2018/00285—Balloons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00547—Prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00577—Ablation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00791—Temperature
- A61B2018/00821—Temperature measured by a thermocouple
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00869—Phase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00875—Resistance or impedance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00898—Alarms or notifications created in response to an abnormal condition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00982—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body combined with or comprising means for visual or photographic inspections inside the body, e.g. endoscopes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B2018/044—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating the surgical action being effected by a circulating hot fluid
- A61B2018/048—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating the surgical action being effected by a circulating hot fluid in gaseous form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/04—Protection of tissue around surgical sites against effects of non-mechanical surgery, e.g. laser surgery
- A61B2090/0409—Specification of type of protection measures
- A61B2090/0427—Prevention of contact
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/04—Protection of tissue around surgical sites against effects of non-mechanical surgery, e.g. laser surgery
- A61B2090/0409—Specification of type of protection measures
- A61B2090/0436—Shielding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/1782—Devices aiding filling of syringes in situ
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/204—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically connected to external reservoirs for multiple refilling
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Otolaryngology (AREA)
- Plasma & Fusion (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Pathology (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Surgical Instruments (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
本出願は、2017年1月6日に出願された米国仮特許出願第62/443、555号に対する優先権の利益を主張するものであり、この文献は引用により本明細書に組み入れられる。
大量の蒸気をBPHシステムよりも高い割合で長い時間にわたって送出できる癌蒸気治療システムの要件としては、より多くの総滅菌水量に十分な電力を供給することが挙げられる。図1A~図1Bのシステムは、300~600kHzの範囲の周波数で最大500ワットのRF電力を供給することができる。
図3A~図3Bに示す蒸気発生送出ハンドル106は、ハンドル部分150と、治療送出ボタン152と、蒸気送出針のためのルアー継手154と、蒸気発生送出ハンドルをRF発生器に接続するケーブル及びコネクタ156を含む。図3Bに示すように、蒸気発生送出ハンドルは、更に、加熱素子158と、患者内に配置される針に取付けられるルアー継手を含み、加熱素子158は、押出し加工された高温PFA絶縁体を含むリッツ線のRFコイルと、インコネル(登録商標)625の内側コイルと、コイル及び出口用の熱電対を有する。
前立腺癌蒸気送出針は、会陰を穿刺し、前立腺被膜を穿刺して、会陰組織を焼灼することなしに前立腺のみに蒸気を送出する必要がある。本発明では、会陰組織に隣接した針の部分を絶縁し、先端を包囲する組織の電気的特性を測定して、蒸気を送出する前に針が前立腺組織内に存在することを検証することによってこれらの要件に対処する。
前立腺癌の蒸気治療を行う場合、医師は、患者の前立腺の周辺領域及び/又は移行領域内に蒸気送出針の先端を配置する必要がある。これを行うために、患者の会陰に針を挿通し、超音波ガイダンスを利用して、適切な前立腺領域への操縦を行う。場合によっては、針を適所に配置し、治療を行い、針を前立腺の先端部に向けて引戻し又は前立腺の基部に向けて押進め、その後に別の治療を行うように、単一の針を用いて複数回の蒸気治療を行う。このプロセスを、針の軸の周囲に連続する治療済み組織の領域が形成されるまで繰返す。
本発明は、蒸気送出針の先端に電極を組込む。電極間に高周波電流を流し、結果として生じる電極間の電圧、並びに電圧と電流との間の位相シフトを測定する。これらの測定は、針の先端を包囲する組織の性質に依存する。組織は、その内容に応じて電気的に抵抗性及び/又は電気的に容量性となり得る。具体的には、この測定によって前立腺組織が周囲組織と区別され、蒸気の送出前に蒸気送出針が前立腺内に存在するという明確な判断が可能になる。
図4Cに、治療中に蒸気を放出する4つの放出孔を3列有する蒸気送出針の先端123を示す。この先端は、それ自体がバイオコンデンサー測定のための第1の電極である。第2の電極は、PTFE絶縁体182の部分によって針の先端から電気的に分離されたリング電極180である。絶縁されたニッケルワイヤがこの電極に溶接され、針の長さにわたって延びる。蒸気針アセンブリの内部では、これらの2つの電極が、雄型MMCXコネクタにおいて終端するMMCV同軸ケーブルの6”セグメントにはんだ付けされる。蒸気針は、8’MMCX同軸延長ケーブル及びMMXCからN型へのアダプタ(MMXC to N-type adapter)を介してシステム発生器(system generator)内のベクトル電圧計回路に接続される。この回路は、1~100MHzで変動できる周波数の交流電流を供給し、初期周波数掃引を行って前立腺内の組織と前立腺の外側の組織の間のインピーダンスと位相のコントラストを最適化する作動周波数を決定する。インピーダンス振幅及び位相は、システムコンピュータにおいて分析されるベクトル電圧計回路の出力である。
図1Bに示す尿道冷却カテーテル110は、先端が膀胱内に至るまで尿道に挿通される。10ccシリンジを介して固定バルーン113を生理食塩水で膨らませて先端を係止する。カテーテルを引戻して、固定バルーン113を膀胱壁の内部に係合させる。これらのステップは、フォーリーカテーテルの挿入と同様である。
蒸気治療は、前治療MRI及び/又は超音波画像、並びに前立腺の生検に基づいて事前に計画することができる。治療計画は、癌であると診断された前立腺の領域における蒸気送出針の配置を含む。個々の針は、所与の領域に複数回の治療投与を適用することができる。1つの経験則としては、蒸気治療を行った組織は、未治療の組織よりも超音波に対する透過性が低く、従ってその後の治療投与に対する最適な可視化を保証するために超音波トランスデューサから最も遠い組織を最初に治療することが挙げられる。
Claims (15)
- 蒸気送出装置であって、
シャフトと、
前記シャフトに配置された第1の電極と、
前記第1の電極と近接して前記シャフトに配置された第2の電極と、
前記第1の電極と前記第2の電極の間に配置された電気絶縁材料と、
電子コントローラと、を有し、
前記第1の電極は、前記第1の電極に接触している第1の組織の第1の電気インピーダンスを測定するように構成され、
前記第2の電極は、前記第2の電極に接触している第2の組織の第2の電気インピーダンスを測定するように構成され、
前記電子コントローラは、前記第1の電極及び前記第2の電極が前立腺内に配置されているかどうかを決定するために、前記第1の電気インピーダンス及び前記第2の電気インピーダンスを使用するように構成される、蒸気送出装置。 - 前記第2の電極は、リング電極である、請求項1に記載の蒸気送出装置。
- 前記第1の電極は、前記第1の組織の第1の位相シフトを測定するように構成される、請求項1又は2に記載の蒸気送出装置。
- 前記第2の電極は、前記第2の組織の第2の位相シフトを測定するように構成される、請求項3に記載の蒸気送出装置。
- 前記電子コントローラは、前記第1の電極及び前記第2の電極が前立腺内に配置されているかどうかを決定するために、前記第1の位相シフト及び前記第2の位相シフトを使用するように構成される、請求項4に記載の蒸気送出装置。
- 前記電子コントローラは、前記第1の電気インピーダンス及び前記第1の位相シフトに基づいて、第1の複合スコアを計算するように構成される、請求項4又は5に記載の蒸気送出装置。
- 更に、ユーザインターフェイスを有し、前記ユーザインターフェイスは、第1の複合スコアを第1の電気インピーダンス又は第1の位相シフトに向かって偏向させるスライド目盛りを含む、請求項6に記載の蒸気送出装置。
- 前記電子コントローラは、前記第2のインピーダンス及び前記第2の位相シフトに基づいて、第2の複合スコアを計算するように構成される、請求項4~7の何れか1項に記載の蒸気送出装置。
- 前記ユーザインターフェイスは、前記第2の複合スコアを前記第2の電気インピーダンス又は前記第2の位相シフトに向かって偏向させるスライド目盛りを含む、請求項10に記載の蒸気送出装置。
- 前記シャフトは、蒸気を前立腺に送出するように構成された少なくとも1つの孔を含む、請求項1~9の何れか1項に記載の蒸気送出装置。
- 蒸気が、前記第1の電極及び前記第2の電極が両方とも前立腺の中に配置されていることを電気コントローラによって決定したときだけ、前記シャフトによって少なくとも1つの孔を通して送出可能である、請求項10に記載の蒸気送出装置。
- 更に、前記第1の電極及び前記第2の電極に電気的に接続された回路を有し、前記回路は、可変周波数を供給するように構成される、請求項1~11の何れか1項に記載の蒸気送出装置。
- 前記第1の電気インピーダンス及び前記第2の電気インピーダンスの少なくとも一方を最適化する作動周波数を決定するために、前記回路は、周波数掃引を行うように構成される、請求項12に記載の蒸気送出装置。
- 蒸気は、前記第1の電極及び前記第2の電極が前立腺内に配置されているときだけ前記前記シャフトによって送出可能である、請求項1~13の何れか1項に記載の蒸気送出装置。
- 前記第1の電極は、前記シャフトの遠位先端のところに配置される、請求項1~14の何れか1項に記載の蒸気送出装置。
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762443555P | 2017-01-06 | 2017-01-06 | |
US62/443,555 | 2017-01-06 | ||
PCT/US2018/012815 WO2018129466A1 (en) | 2017-01-06 | 2018-01-08 | Transperineal vapor ablation systems and methods |
JP2019536304A JP7193463B2 (ja) | 2017-01-06 | 2018-01-08 | 経腹膜蒸気焼灼システム及び方法 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2019536304A Division JP7193463B2 (ja) | 2017-01-06 | 2018-01-08 | 経腹膜蒸気焼灼システム及び方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2023026458A true JP2023026458A (ja) | 2023-02-24 |
JP7481418B2 JP7481418B2 (ja) | 2024-05-10 |
Family
ID=62782074
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2019536304A Active JP7193463B2 (ja) | 2017-01-06 | 2018-01-08 | 経腹膜蒸気焼灼システム及び方法 |
JP2022196084A Active JP7481418B2 (ja) | 2017-01-06 | 2022-12-08 | 経腹膜蒸気焼灼システム及び方法 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2019536304A Active JP7193463B2 (ja) | 2017-01-06 | 2018-01-08 | 経腹膜蒸気焼灼システム及び方法 |
Country Status (6)
Country | Link |
---|---|
US (2) | US10751107B2 (ja) |
EP (2) | EP4356944A2 (ja) |
JP (2) | JP7193463B2 (ja) |
CN (1) | CN110167473A (ja) |
AU (2) | AU2018205314B2 (ja) |
WO (1) | WO2018129466A1 (ja) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9833277B2 (en) | 2009-04-27 | 2017-12-05 | Nxthera, Inc. | Systems and methods for prostate treatment |
JP6422975B2 (ja) | 2013-12-10 | 2018-11-14 | エヌエックスセラ インコーポレイテッド | 蒸気焼灼システム及び方法 |
US10945789B2 (en) * | 2018-04-06 | 2021-03-16 | Elesta S.p.A. | Laser treatment of benign prostatic hypertrophy |
US20210220051A1 (en) * | 2018-04-06 | 2021-07-22 | Elesta S.p.A. | Laser treatment of the prostate |
AU2020419190A1 (en) * | 2019-12-30 | 2022-07-14 | Francis Medical, Inc. | Vapor therapy systems and methods |
AU2021251123A1 (en) * | 2020-04-06 | 2022-10-20 | Corbin Clinical Resources, Llc | Transperineal prostate biopsy and treatment methods |
CN113813042B (zh) * | 2021-10-22 | 2023-12-05 | 杭州维纳安可医疗科技有限责任公司 | 电极针及电极装置 |
Family Cites Families (285)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US408899A (en) | 1889-08-13 | Island | ||
US1719750A (en) | 1927-09-29 | 1929-07-02 | Charles E Parkhurst | Dental apparatus |
US5542915A (en) | 1992-08-12 | 1996-08-06 | Vidamed, Inc. | Thermal mapping catheter with ultrasound probe |
US5370675A (en) | 1992-08-12 | 1994-12-06 | Vidamed, Inc. | Medical probe device and method |
US5385544A (en) | 1992-08-12 | 1995-01-31 | Vidamed, Inc. | BPH ablation method and apparatus |
US5421819A (en) | 1992-08-12 | 1995-06-06 | Vidamed, Inc. | Medical probe device |
US5435805A (en) | 1992-08-12 | 1995-07-25 | Vidamed, Inc. | Medical probe device with optical viewing capability |
US4672963A (en) | 1985-06-07 | 1987-06-16 | Israel Barken | Apparatus and method for computer controlled laser surgery |
JPH01139081A (ja) | 1987-11-27 | 1989-05-31 | Olympus Optical Co Ltd | レーザ光照射装置 |
US4920982A (en) | 1988-06-27 | 1990-05-01 | Vastech Medical Products Inc. | Percutaneous vasectomy method |
US5249585A (en) | 1988-07-28 | 1993-10-05 | Bsd Medical Corporation | Urethral inserted applicator for prostate hyperthermia |
US5117482A (en) | 1990-01-16 | 1992-05-26 | Automated Dynamics Corporation | Porous ceramic body electrical resistance fluid heater |
CN2061443U (zh) | 1990-02-24 | 1990-09-05 | 山东省泰安市中心医院 | 医用泵式水刀 |
CA2048120A1 (en) | 1990-08-06 | 1992-02-07 | William J. Drasler | Thrombectomy method and device |
ES2075676T3 (es) | 1990-12-10 | 1995-10-01 | Howmedica | Dispositivo y procedimiento para la aplicacion intersticial de energia laser. |
US5409453A (en) | 1992-08-12 | 1995-04-25 | Vidamed, Inc. | Steerable medical probe with stylets |
US7549424B2 (en) | 1991-10-18 | 2009-06-23 | Pro Surg, Inc. | Method and apparatus for tissue treatment with laser and electromagnetic radiation |
US6461296B1 (en) | 1998-06-26 | 2002-10-08 | 2000 Injectx, Inc. | Method and apparatus for delivery of genes, enzymes and biological agents to tissue cells |
US6231591B1 (en) | 1991-10-18 | 2001-05-15 | 2000 Injectx, Inc. | Method of localized fluid therapy |
US6974453B2 (en) | 1993-05-10 | 2005-12-13 | Arthrocare Corporation | Dual mode electrosurgical clamping probe and related methods |
US7429262B2 (en) | 1992-01-07 | 2008-09-30 | Arthrocare Corporation | Apparatus and methods for electrosurgical ablation and resection of target tissue |
US5902272A (en) | 1992-01-07 | 1999-05-11 | Arthrocare Corporation | Planar ablation probe and method for electrosurgical cutting and ablation |
MX9300607A (es) | 1992-02-06 | 1993-10-01 | American Med Syst | Aparato y metodo para tratamiento intersticial. |
US5370677A (en) | 1992-03-06 | 1994-12-06 | Urologix, Inc. | Gamma matched, helical dipole microwave antenna with tubular-shaped capacitor |
US5330518A (en) | 1992-03-06 | 1994-07-19 | Urologix, Inc. | Method for treating interstitial tissue associated with microwave thermal therapy |
US5300099A (en) | 1992-03-06 | 1994-04-05 | Urologix, Inc. | Gamma matched, helical dipole microwave antenna |
US5413588A (en) | 1992-03-06 | 1995-05-09 | Urologix, Inc. | Device and method for asymmetrical thermal therapy with helical dipole microwave antenna |
US5222185A (en) | 1992-03-26 | 1993-06-22 | Mccord Jr Harry C | Portable water heater utilizing combined fluid-in-circuit and induction heating effects |
US5341807A (en) * | 1992-06-30 | 1994-08-30 | American Cardiac Ablation Co., Inc. | Ablation catheter positioning system |
US5556377A (en) | 1992-08-12 | 1996-09-17 | Vidamed, Inc. | Medical probe apparatus with laser and/or microwave monolithic integrated circuit probe |
US5470308A (en) | 1992-08-12 | 1995-11-28 | Vidamed, Inc. | Medical probe with biopsy stylet |
US5630794A (en) | 1992-08-12 | 1997-05-20 | Vidamed, Inc. | Catheter tip and method of manufacturing |
US5667488A (en) | 1992-08-12 | 1997-09-16 | Vidamed, Inc. | Transurethral needle ablation device and method for the treatment of the prostate |
US5484400A (en) | 1992-08-12 | 1996-01-16 | Vidamed, Inc. | Dual channel RF delivery system |
US5672153A (en) | 1992-08-12 | 1997-09-30 | Vidamed, Inc. | Medical probe device and method |
US5542916A (en) | 1992-08-12 | 1996-08-06 | Vidamed, Inc. | Dual-channel RF power delivery system |
US5720718A (en) | 1992-08-12 | 1998-02-24 | Vidamed, Inc. | Medical probe apparatus with enhanced RF, resistance heating, and microwave ablation capabilities |
US5720719A (en) | 1992-08-12 | 1998-02-24 | Vidamed, Inc. | Ablative catheter with conformable body |
AU5008293A (en) | 1992-08-17 | 1994-03-15 | Thomas L. Mehl | Hand-held, multi-purpose portable steamer |
US5312399A (en) | 1992-09-29 | 1994-05-17 | Hakky Said I | Laser resectoscope with mechanical cutting means and laser coagulating means |
DE4235506A1 (de) | 1992-10-21 | 1994-04-28 | Bavaria Med Tech | Katheter zur Injektion von Arzneimitteln |
EP0631514A4 (en) | 1993-02-02 | 1995-04-26 | Vidamed Inc | METHOD AND DEVICE FOR ABLATION WITH A TRANSURETRAL NEEDLE. |
CA2164860C (en) | 1993-06-10 | 2005-09-06 | Mir A. Imran | Transurethral radio frequency ablation apparatus |
US5464437A (en) | 1993-07-08 | 1995-11-07 | Urologix, Inc. | Benign prostatic hyperplasia treatment catheter with urethral cooling |
US5709680A (en) | 1993-07-22 | 1998-01-20 | Ethicon Endo-Surgery, Inc. | Electrosurgical hemostatic device |
US5807395A (en) | 1993-08-27 | 1998-09-15 | Medtronic, Inc. | Method and apparatus for RF ablation and hyperthermia |
DE4496959T1 (de) | 1993-09-14 | 1996-09-26 | Microsurge Inc | Endoskopisches chirurgisches Instrument mit geführten Klemmbacken bzw. Backen und Sperrsteuerung |
US5797903A (en) | 1996-04-12 | 1998-08-25 | Ep Technologies, Inc. | Tissue heating and ablation systems and methods using porous electrode structures with electrically conductive surfaces |
US5545171A (en) | 1994-09-22 | 1996-08-13 | Vidamed, Inc. | Anastomosis catheter |
US5601591A (en) | 1994-09-23 | 1997-02-11 | Vidamed, Inc. | Stent for use in prostatic urethra, apparatus and placement device for same and method |
US5558673A (en) | 1994-09-30 | 1996-09-24 | Vidamed, Inc. | Medical probe device and method having a flexible resilient tape stylet |
US5531763A (en) | 1994-10-07 | 1996-07-02 | United States Surgical Corporation | Suture cinching apparatus |
US5588960A (en) | 1994-12-01 | 1996-12-31 | Vidamed, Inc. | Transurethral needle delivery device with cystoscope and method for treatment of urinary incontinence |
US6544211B1 (en) | 1995-02-06 | 2003-04-08 | Mark S. Andrew | Tissue liquefaction and aspiration |
US6409722B1 (en) | 1998-07-07 | 2002-06-25 | Medtronic, Inc. | Apparatus and method for creating, maintaining, and controlling a virtual electrode used for the ablation of tissue |
US6063081A (en) | 1995-02-22 | 2000-05-16 | Medtronic, Inc. | Fluid-assisted electrocautery device |
US5897553A (en) | 1995-11-02 | 1999-04-27 | Medtronic, Inc. | Ball point fluid-assisted electrocautery device |
JPH08264272A (ja) | 1995-03-27 | 1996-10-11 | Seta Giken:Kk | 電磁誘導加熱装置 |
US6221045B1 (en) * | 1995-04-20 | 2001-04-24 | Acist Medical Systems, Inc. | Angiographic injector system with automatic high/low pressure switching |
US5645528A (en) | 1995-06-06 | 1997-07-08 | Urologix, Inc. | Unitary tip and balloon for transurethral catheter |
US5628770A (en) | 1995-06-06 | 1997-05-13 | Urologix, Inc. | Devices for transurethral thermal therapy |
US6238391B1 (en) | 1995-06-07 | 2001-05-29 | Arthrocare Corporation | Systems for tissue resection, ablation and aspiration |
US5849011A (en) | 1995-06-19 | 1998-12-15 | Vidamed, Inc. | Medical device with trigger actuation assembly |
US6607529B1 (en) | 1995-06-19 | 2003-08-19 | Medtronic Vidamed, Inc. | Electrosurgical device |
US5843144A (en) | 1995-06-26 | 1998-12-01 | Urologix, Inc. | Method for treating benign prostatic hyperplasia with thermal therapy |
US6036713A (en) | 1996-01-24 | 2000-03-14 | Archimedes Surgical, Inc. | Instruments and methods for minimally invasive vascular procedures |
GB9605206D0 (en) | 1996-03-12 | 1996-05-15 | Boc Group Plc | Medical devices |
US5938692A (en) | 1996-03-26 | 1999-08-17 | Urologix, Inc. | Voltage controlled variable tuning antenna |
US5830179A (en) * | 1996-04-09 | 1998-11-03 | Endocare, Inc. | Urological stent therapy system and method |
US5733319A (en) | 1996-04-25 | 1998-03-31 | Urologix, Inc. | Liquid coolant supply system |
US5987360A (en) | 1996-05-03 | 1999-11-16 | Urologix, Inc. | Axial preferential thermal therapy |
US6077257A (en) | 1996-05-06 | 2000-06-20 | Vidacare, Inc. | Ablation of rectal and other internal body structures |
US5776176A (en) | 1996-06-17 | 1998-07-07 | Urologix Inc. | Microwave antenna for arterial for arterial microwave applicator |
US5800486A (en) | 1996-06-17 | 1998-09-01 | Urologix, Inc. | Device for transurethral thermal therapy with cooling balloon |
US5861021A (en) | 1996-06-17 | 1999-01-19 | Urologix Inc | Microwave thermal therapy of cardiac tissue |
US6565561B1 (en) | 1996-06-20 | 2003-05-20 | Cyrus Medical Limited | Electrosurgical instrument |
GB2314274A (en) | 1996-06-20 | 1997-12-24 | Gyrus Medical Ltd | Electrode construction for an electrosurgical instrument |
US5976123A (en) | 1996-07-30 | 1999-11-02 | Laser Aesthetics, Inc. | Heart stabilization |
US5792070A (en) | 1996-08-30 | 1998-08-11 | Urologix, Inc. | Rectal thermosensing unit |
US6017361A (en) | 1997-03-13 | 2000-01-25 | Endo Care, Inc. | Urethral warming catheter |
US5873877A (en) | 1997-04-11 | 1999-02-23 | Vidamed, Inc. | Medical probe device with transparent distal extremity |
US5964756A (en) | 1997-04-11 | 1999-10-12 | Vidamed, Inc. | Transurethral needle ablation device with replaceable stylet cartridge |
US5871481A (en) | 1997-04-11 | 1999-02-16 | Vidamed, Inc. | Tissue ablation apparatus and method |
US6017358A (en) | 1997-05-01 | 2000-01-25 | Inbae Yoon | Surgical instrument with multiple rotatably mounted offset end effectors |
US6223085B1 (en) | 1997-05-06 | 2001-04-24 | Urologix, Inc. | Device and method for preventing restenosis |
US6009351A (en) | 1997-07-14 | 1999-12-28 | Urologix, Inc. | System and method for transurethral heating with rectal cooling |
US6123083A (en) | 1997-08-29 | 2000-09-26 | Urologix, Inc. | Device and method for treatment of a prostate while preventing urethral constriction due to collagen rich tissue shrinkage |
US6238389B1 (en) | 1997-09-30 | 2001-05-29 | Boston Scientific Corporation | Deflectable interstitial ablation device |
US5964752A (en) | 1998-02-02 | 1999-10-12 | Stone; Kevin R. | Articular cartilage surface shaping apparatus and method |
US6517534B1 (en) | 1998-02-11 | 2003-02-11 | Cosman Company, Inc. | Peri-urethral ablation |
US6440127B2 (en) | 1998-02-11 | 2002-08-27 | Cosman Company, Inc. | Method for performing intraurethral radio-frequency urethral enlargement |
US6258087B1 (en) | 1998-02-19 | 2001-07-10 | Curon Medical, Inc. | Expandable electrode assemblies for forming lesions to treat dysfunction in sphincters and adjoining tissue regions |
US6147336A (en) | 1998-02-26 | 2000-11-14 | Japanese Research And Development Association For Application Of Electronic Technology In Food Industry | Induction heaters for heating food, fluids or the like |
US6183442B1 (en) * | 1998-03-02 | 2001-02-06 | Board Of Regents Of The University Of Texas System | Tissue penetrating device and methods for using same |
US6036631A (en) | 1998-03-09 | 2000-03-14 | Urologix, Inc. | Device and method for intracavitary cancer treatment |
US6053909A (en) | 1998-03-27 | 2000-04-25 | Shadduck; John H. | Ionothermal delivery system and technique for medical procedures |
US6210404B1 (en) | 1998-10-28 | 2001-04-03 | John H. Shadduck | Microjoule electrical discharge catheter for thrombolysis in stroke patients |
US7674259B2 (en) | 2000-12-09 | 2010-03-09 | Tsunami Medtech | Medical instruments and techniques for thermally-mediated therapies |
US8016823B2 (en) | 2003-01-18 | 2011-09-13 | Tsunami Medtech, Llc | Medical instrument and method of use |
US6911028B2 (en) | 1998-10-28 | 2005-06-28 | John H. Shadduck | Medical instrument working end and method for endoluminal treatments |
US7892229B2 (en) | 2003-01-18 | 2011-02-22 | Tsunami Medtech, Llc | Medical instruments and techniques for treating pulmonary disorders |
US6508816B2 (en) | 1998-03-27 | 2003-01-21 | John H. Shadduck | Medical instrument working end creating very high pressure gradients |
US6669694B2 (en) | 2000-09-05 | 2003-12-30 | John H. Shadduck | Medical instruments and techniques for highly-localized thermally-mediated therapies |
JP2000005191A (ja) | 1998-06-25 | 2000-01-11 | Olympus Optical Co Ltd | 高周波治療装置 |
US6216703B1 (en) | 1998-05-08 | 2001-04-17 | Thermatrx, Inc. | Therapeutic prostatic thermotherapy |
JPH11318925A (ja) | 1998-05-21 | 1999-11-24 | Olympus Optical Co Ltd | 医療用プローブ |
US6398759B1 (en) | 1998-06-04 | 2002-06-04 | Alcon Manufacturing, Ltd. | Liquefracture handpiece tip |
US6676628B2 (en) | 1998-06-04 | 2004-01-13 | Alcon Manufacturing, Ltd. | Pumping chamber for a liquefracture handpiece |
US6589201B1 (en) | 1998-06-04 | 2003-07-08 | Alcon Manufacturing, Ltd. | Liquefracture handpiece tip |
US6179805B1 (en) | 1998-06-04 | 2001-01-30 | Alcon Laboratories, Inc. | Liquefracture handpiece |
US6579270B2 (en) | 1998-06-04 | 2003-06-17 | Alcon Manufacturing, Ltd. | Liquefracture handpiece tip |
JP2000014663A (ja) | 1998-06-30 | 2000-01-18 | Olympus Optical Co Ltd | 前立腺肥大治療用装置 |
US6537248B2 (en) | 1998-07-07 | 2003-03-25 | Medtronic, Inc. | Helical needle apparatus for creating a virtual electrode used for the ablation of tissue |
US6706039B2 (en) | 1998-07-07 | 2004-03-16 | Medtronic, Inc. | Method and apparatus for creating a bi-polar virtual electrode used for the ablation of tissue |
US6494902B2 (en) | 1998-07-07 | 2002-12-17 | Medtronic, Inc. | Method for creating a virtual electrode for the ablation of tissue and for selected protection of tissue during an ablation |
US6537272B2 (en) | 1998-07-07 | 2003-03-25 | Medtronic, Inc. | Apparatus and method for creating, maintaining, and controlling a virtual electrode used for the ablation of tissue |
US6238393B1 (en) | 1998-07-07 | 2001-05-29 | Medtronic, Inc. | Method and apparatus for creating a bi-polar virtual electrode used for the ablation of tissue |
US6315777B1 (en) | 1998-07-07 | 2001-11-13 | Medtronic, Inc. | Method and apparatus for creating a virtual electrode used for the ablation of tissue |
US6302903B1 (en) | 1998-07-07 | 2001-10-16 | Medtronic, Inc. | Straight needle apparatus for creating a virtual electrode used for the ablation of tissue |
WO2000023147A1 (en) | 1998-10-20 | 2000-04-27 | Dornier Medtech Holding International Gmbh | Thermal therapy with tissue protection |
US6148236A (en) | 1998-11-04 | 2000-11-14 | Urologix, Inc. | Cancer treatment system employing supplemented thermal therapy |
US6067475A (en) | 1998-11-05 | 2000-05-23 | Urologix, Inc. | Microwave energy delivery system including high performance dual directional coupler for precisely measuring forward and reverse microwave power during thermal therapy |
JP4129500B2 (ja) | 1998-11-17 | 2008-08-06 | サントル・デチュード・エ・ドゥ・レシェルシュ・メディカル・ダルシャン−セルマ | 活性物質を細胞組織内へと直接的に搬送するためのデバイスおよびこのようなデバイスの埋設手段ならびにデバイス内に活性物質を注入することを意図した器具 |
US6122551A (en) | 1998-12-11 | 2000-09-19 | Urologix, Inc. | Method of controlling thermal therapy |
US6113593A (en) | 1999-02-01 | 2000-09-05 | Tu; Lily Chen | Ablation apparatus having temperature and force sensing capabilities |
US6287297B1 (en) | 1999-03-05 | 2001-09-11 | Plc Medical Systems, Inc. | Energy delivery system and method for performing myocardial revascular |
DE19912844A1 (de) | 1999-03-22 | 2000-09-28 | Saphir Medical Products Gmbh | Verwendung eines Schneidegerätes, welches ein Fluid als Schneidemedium einsetzt, zur chirurgischen Behandlung |
US6161049A (en) | 1999-03-26 | 2000-12-12 | Urologix, Inc. | Thermal therapy catheter |
US6348039B1 (en) | 1999-04-09 | 2002-02-19 | Urologix, Inc. | Rectal temperature sensing probe |
US6272384B1 (en) | 1999-05-27 | 2001-08-07 | Urologix, Inc. | Microwave therapy apparatus |
US6156036A (en) | 1999-06-11 | 2000-12-05 | Alcon Laboratories, Inc. | Surgical handpiece tip |
JP2003510159A (ja) | 1999-10-05 | 2003-03-18 | オムニソニクス メディカル テクノロジーズ インコーポレイテッド | 特に前立腺を縮小させる超音波治療方法および超音波治療装置 |
SE515932C2 (sv) | 1999-12-23 | 2001-10-29 | Prostalund Operations Ab | Sätt och anordning vid behandling av prostata |
US6312391B1 (en) | 2000-02-16 | 2001-11-06 | Urologix, Inc. | Thermodynamic modeling of tissue treatment procedure |
US6575929B2 (en) | 2000-03-14 | 2003-06-10 | Alcon Manufacturing, Ltd. | Pumping chamber for a liquefaction handpiece |
US6988983B2 (en) | 2000-04-14 | 2006-01-24 | Solace Therapeutics, Inc. | Implantable self-inflating attenuation device |
WO2001078618A1 (en) | 2000-04-14 | 2001-10-25 | American Medical Systems, Inc. | Method and apparatus for coagulation of superficial blood vessels in bladder and proximal urethra |
CN2418844Y (zh) | 2000-05-11 | 2001-02-14 | 中国科学院低温技术实验中心 | 用于肿瘤治疗的微创型蒸汽探针热疗仪 |
EP1289415A4 (en) | 2000-05-18 | 2008-12-03 | Nuvasive Inc | TISSUE DISTRACTION AND APPLICATIONS IN MEDICAL PROCEDURES |
US6716252B2 (en) | 2000-06-30 | 2004-04-06 | Wit Ip Corporation | Prostatic stent with localized tissue engaging anchoring means and methods for inhibiting obstruction of the prostatic urethra |
EP1306101B1 (en) | 2000-07-12 | 2008-11-05 | Nipro Corporation | Safe retained needle |
US6965732B2 (en) | 2000-08-22 | 2005-11-15 | A.T.C.T. Advanced Thermal Chips Technologies Ltd. | Liquid heating method and apparatus particularly useful for vaporizing a liquid condensate from cooling devices |
US6551300B1 (en) | 2000-10-04 | 2003-04-22 | Vidamed, Inc. | Device and method for delivery of topically applied local anesthetic to wall forming a passage in tissue |
US6638275B1 (en) | 2000-10-05 | 2003-10-28 | Medironic, Inc. | Bipolar ablation apparatus and method |
US7549987B2 (en) | 2000-12-09 | 2009-06-23 | Tsunami Medtech, Llc | Thermotherapy device |
US6681998B2 (en) | 2000-12-22 | 2004-01-27 | Chrysalis Technologies Incorporated | Aerosol generator having inductive heater and method of use thereof |
US20020087151A1 (en) | 2000-12-29 | 2002-07-04 | Afx, Inc. | Tissue ablation apparatus with a sliding ablation instrument and method |
US6743226B2 (en) | 2001-02-09 | 2004-06-01 | Cosman Company, Inc. | Adjustable trans-urethral radio-frequency ablation |
US20020177846A1 (en) | 2001-03-06 | 2002-11-28 | Mulier Peter M.J. | Vaporous delivery of thermal energy to tissue sites |
US6740108B1 (en) | 2001-04-05 | 2004-05-25 | Urologix, Inc. | Thermal treatment catheter having preferential asymmetrical heating pattern |
US6726696B1 (en) | 2001-04-24 | 2004-04-27 | Advanced Catheter Engineering, Inc. | Patches and collars for medical applications and methods of use |
US7344507B2 (en) | 2002-04-19 | 2008-03-18 | Pelikan Technologies, Inc. | Method and apparatus for lancet actuation |
WO2003088851A1 (en) | 2001-06-12 | 2003-10-30 | Pelikan Technologies, Inc. | Tissue penetration device |
US7015253B2 (en) | 2001-07-10 | 2006-03-21 | American Medical Systems, Inc. | Regimen for treating prostate tissue and surgical kit for use in the regimen |
CA2453410A1 (en) | 2001-07-27 | 2003-02-13 | Wit Ip Corporation | Methods for treating prostatitis |
US7130697B2 (en) | 2002-08-13 | 2006-10-31 | Minnesota Medical Physics Llc | Apparatus and method for the treatment of benign prostatic hyperplasia |
US6827718B2 (en) | 2001-08-14 | 2004-12-07 | Scimed Life Systems, Inc. | Method of and apparatus for positioning and maintaining the position of endoscopic instruments |
WO2003030756A2 (en) | 2001-10-12 | 2003-04-17 | Ams Research Corporation | Surgical instrument and method |
US8444636B2 (en) | 2001-12-07 | 2013-05-21 | Tsunami Medtech, Llc | Medical instrument and method of use |
US7041121B1 (en) | 2002-01-31 | 2006-05-09 | Medtronicvidamed, Inc. | Apparatus for treating prostate cancer and method for same |
US7288109B2 (en) | 2002-04-04 | 2007-10-30 | Innercool Therapies. Inc. | Method of manufacturing a heat transfer element for in vivo cooling without undercuts |
US6974455B2 (en) | 2002-04-10 | 2005-12-13 | Boston Scientific Scimed, Inc. | Auto advancing radio frequency array |
AU2003237089B2 (en) | 2002-04-22 | 2009-01-22 | The Johns Hopkins University | Apparatus for insertion of a medical device during a medical imaging process |
US6780178B2 (en) | 2002-05-03 | 2004-08-24 | The Board Of Trustees Of The Leland Stanford Junior University | Method and apparatus for plasma-mediated thermo-electrical ablation |
IL149706A0 (en) | 2002-05-16 | 2002-11-10 | Dolopaz Technologies Ltd | Multipurpose fluid jet surgical device |
US7458967B2 (en) | 2003-10-31 | 2008-12-02 | Angiodynamics, Inc. | Endovascular treatment apparatus and method |
US6855141B2 (en) | 2002-07-22 | 2005-02-15 | Medtronic, Inc. | Method for monitoring impedance to control power and apparatus utilizing same |
US6730079B2 (en) | 2002-07-22 | 2004-05-04 | Medtronic Vidamed, Inc. | Method for calculating impedance and apparatus utilizing same |
US6887237B2 (en) | 2002-07-22 | 2005-05-03 | Medtronic, Inc. | Method for treating tissue with a wet electrode and apparatus for using same |
US7369894B2 (en) | 2002-09-06 | 2008-05-06 | Medtronic, Inc. | Method, system and device for treating disorders of the pelvic floor by electrical stimulation of the sacral and/or pudendal nerves |
US7328068B2 (en) | 2003-03-31 | 2008-02-05 | Medtronic, Inc. | Method, system and device for treating disorders of the pelvic floor by means of electrical stimulation of the pudendal and associated nerves, and the optional delivery of drugs in association therewith |
US7328069B2 (en) | 2002-09-06 | 2008-02-05 | Medtronic, Inc. | Method, system and device for treating disorders of the pelvic floor by electrical stimulation of and the delivery of drugs to the left and right pudendal nerves |
US20040267340A1 (en) | 2002-12-12 | 2004-12-30 | Wit Ip Corporation | Modular thermal treatment systems with single-use disposable catheter assemblies and related methods |
US7273479B2 (en) | 2003-01-15 | 2007-09-25 | Cryodynamics, Llc | Methods and systems for cryogenic cooling |
US8512290B2 (en) | 2003-03-20 | 2013-08-20 | Boston Scientific Scimed, Inc. | Devices and methods for delivering therapeutic or diagnostic agents |
US7238182B2 (en) | 2003-04-25 | 2007-07-03 | Medtronic, Inc. | Device and method for transurethral prostate treatment |
US7340300B2 (en) | 2003-04-25 | 2008-03-04 | Medtronic, Inc. | Neurostimulation delivery during transurethral prostate treatment |
US20040230316A1 (en) | 2003-05-12 | 2004-11-18 | Iulian Cioanta | Method for treating the prostate and inhibiting obstruction of the prostatic urethra using biodegradable stents |
WO2005009213A2 (en) | 2003-07-16 | 2005-02-03 | Arthrocare Corporation | Rotary electrosurgical apparatus and methods thereof |
US7494473B2 (en) | 2003-07-30 | 2009-02-24 | Intact Medical Corp. | Electrical apparatus and system with improved tissue capture component |
US20050159676A1 (en) | 2003-08-13 | 2005-07-21 | Taylor James D. | Targeted biopsy delivery system |
US7763052B2 (en) | 2003-12-05 | 2010-07-27 | N Spine, Inc. | Method and apparatus for flexible fixation of a spine |
US20050096629A1 (en) | 2003-10-31 | 2005-05-05 | Medtronic, Inc. | Techniques for transurethral delivery of a denervating agent to the prostate gland |
US7437194B2 (en) | 2003-10-31 | 2008-10-14 | Medtronic, Inc. | Stimulating the prostate gland |
EP1541091A1 (en) | 2003-12-10 | 2005-06-15 | EL.EN. S.p.A. | Device for treating tumors by laser thermotherapy |
US8409109B2 (en) | 2004-04-01 | 2013-04-02 | Urologix, Inc. | Rectal probe with disposable balloon assembly |
US7066935B2 (en) | 2004-04-30 | 2006-06-27 | Medtronic, Inc. | Ion eluting tuna device |
CN101072544A (zh) | 2004-05-14 | 2007-11-14 | 卡帝玛股份有限公司 | 带稳固构件的消融探针 |
US7894913B2 (en) | 2004-06-10 | 2011-02-22 | Medtronic Urinary Solutions, Inc. | Systems and methods of neuromodulation stimulation for the restoration of sexual function |
SE0401708D0 (sv) | 2004-06-30 | 2004-06-30 | Wallsten Medical Sa | Balloon Catheter |
US8911438B2 (en) | 2004-08-10 | 2014-12-16 | Medtronic, Inc. | Tuna device with integrated saline reservoir |
US7322974B2 (en) | 2004-08-10 | 2008-01-29 | Medtronic, Inc. | TUNA device with integrated saline reservoir |
US7261709B2 (en) | 2004-10-13 | 2007-08-28 | Medtronic, Inc. | Transurethral needle ablation system with automatic needle retraction |
US7335197B2 (en) | 2004-10-13 | 2008-02-26 | Medtronic, Inc. | Transurethral needle ablation system with flexible catheter tip |
US7261710B2 (en) | 2004-10-13 | 2007-08-28 | Medtronic, Inc. | Transurethral needle ablation system |
US7959577B2 (en) | 2007-09-06 | 2011-06-14 | Baxano, Inc. | Method, system, and apparatus for neural localization |
US20060089636A1 (en) | 2004-10-27 | 2006-04-27 | Christopherson Mark A | Ultrasound visualization for transurethral needle ablation |
WO2006050384A2 (en) | 2004-11-01 | 2006-05-11 | Salter Labs | System and method for conserving oxygen delivery while maintaining saturation |
US7585308B2 (en) | 2005-03-30 | 2009-09-08 | Ethicon Endo-Surgery, Inc. | Handle system and method for use in anastomotic procedures |
US7806871B2 (en) | 2005-05-09 | 2010-10-05 | Boston Scientific Scimed, Inc. | Method and device for tissue removal and for delivery of a therapeutic agent or bulking agent |
EP1885438A4 (en) | 2005-05-13 | 2013-01-16 | Ndi Medical Inc | SYSTEMS FOR THE ELECTRICAL STIMULATION OF NERVES IN FAT TWEBEREGIONS |
US7909836B2 (en) | 2005-05-20 | 2011-03-22 | Neotract, Inc. | Multi-actuating trigger anchor delivery system |
US8945152B2 (en) | 2005-05-20 | 2015-02-03 | Neotract, Inc. | Multi-actuating trigger anchor delivery system |
US7896891B2 (en) | 2005-05-20 | 2011-03-01 | Neotract, Inc. | Apparatus and method for manipulating or retracting tissue and anatomical structure |
US20060270916A1 (en) | 2005-05-20 | 2006-11-30 | Medtronic, Inc. | Portable therapy delivery device with a removable connector board |
US7645286B2 (en) | 2005-05-20 | 2010-01-12 | Neotract, Inc. | Devices, systems and methods for retracting, lifting, compressing, supporting or repositioning tissues or anatomical structures |
US7758594B2 (en) | 2005-05-20 | 2010-07-20 | Neotract, Inc. | Devices, systems and methods for treating benign prostatic hyperplasia and other conditions |
US8157815B2 (en) | 2005-05-20 | 2012-04-17 | Neotract, Inc. | Integrated handle assembly for anchor delivery system |
US20070038089A1 (en) | 2005-06-29 | 2007-02-15 | Olympus Medical Systems Corp. | Transurethral diagnostic method and treatment method using ultrasonic endoscope |
US20070032785A1 (en) | 2005-08-03 | 2007-02-08 | Jennifer Diederich | Tissue evacuation device |
US8550743B2 (en) | 2005-09-30 | 2013-10-08 | Medtronic, Inc. | Sliding lock device |
US20110077628A1 (en) | 2006-01-10 | 2011-03-31 | Tsunami Medtech, Llc | Medical system and method of use |
US8241279B2 (en) | 2006-02-23 | 2012-08-14 | Olympus Medical Systems Corp. | Overtube and natural opening medical procedures using the same |
US20070179491A1 (en) | 2006-01-31 | 2007-08-02 | Medtronic, Inc. | Sensing needle for ablation therapy |
US20070213703A1 (en) | 2006-03-13 | 2007-09-13 | Jang Hyun Naam | Electrode for radio frequency tissue ablation |
WO2007130382A2 (en) | 2006-04-29 | 2007-11-15 | Board Of Regents, The University Of Texas System | Devices for use in transluminal and endoluminal surgery |
US7718935B2 (en) | 2006-08-16 | 2010-05-18 | Itherm Technologies, Lp | Apparatus and method for inductive heating of a material in a channel |
US8048069B2 (en) | 2006-09-29 | 2011-11-01 | Medtronic, Inc. | User interface for ablation therapy |
US8585645B2 (en) | 2006-11-13 | 2013-11-19 | Uptake Medical Corp. | Treatment with high temperature vapor |
EP3510959B1 (en) | 2007-01-02 | 2021-03-03 | AquaBeam LLC | Minimally invasive devices for the treatment of prostate diseases |
WO2008086195A1 (en) | 2007-01-05 | 2008-07-17 | Kim Daniel H | Apparatus and method for prostatic tissue removal |
CN100434047C (zh) | 2007-01-18 | 2008-11-19 | 上海交通大学 | 局灶性前列腺癌适形射频消融电极 |
US7896871B2 (en) | 2007-02-22 | 2011-03-01 | Medtronic, Inc. | Impedance computation for ablation therapy |
US8945114B2 (en) | 2007-04-26 | 2015-02-03 | Medtronic, Inc. | Fluid sensor for ablation therapy |
US8814856B2 (en) | 2007-04-30 | 2014-08-26 | Medtronic, Inc. | Extension and retraction mechanism for a hand-held device |
US20080275440A1 (en) | 2007-05-03 | 2008-11-06 | Medtronic, Inc. | Post-ablation verification of lesion size |
US9226731B2 (en) | 2007-05-21 | 2016-01-05 | The Board Of Regents Of The University Of Texas System | Optically guided needle biopsy system using multi-modal spectroscopy in combination with a transrectal ultrasound probe |
US20080297287A1 (en) | 2007-05-30 | 2008-12-04 | Magnetecs, Inc. | Magnetic linear actuator for deployable catheter tools |
US9186207B2 (en) | 2007-06-14 | 2015-11-17 | Medtronic, Inc. | Distal viewing window of a medical catheter |
US20080312521A1 (en) * | 2007-06-14 | 2008-12-18 | Solomon Edward G | System and method for determining electrode-tissue contact using phase difference |
WO2009009398A1 (en) | 2007-07-06 | 2009-01-15 | Tsunami Medtech, Llc | Medical system and method of use |
US8758366B2 (en) | 2007-07-09 | 2014-06-24 | Neotract, Inc. | Multi-actuating trigger anchor delivery system |
US8197470B2 (en) | 2007-08-23 | 2012-06-12 | Aegea Medical, Inc. | Uterine therapy device and method |
JP2011500281A (ja) | 2007-10-22 | 2011-01-06 | アップテイク・メディカル・コーポレイション | 患者に特有の蒸気処置及び供給パラメータを決定する方法 |
GB0801419D0 (en) | 2008-01-25 | 2008-03-05 | Prosurgics Ltd | Albation device |
US9924992B2 (en) | 2008-02-20 | 2018-03-27 | Tsunami Medtech, Llc | Medical system and method of use |
WO2009111736A1 (en) | 2008-03-06 | 2009-09-11 | Aquabeam Llc | Tissue ablation and cautery with optical energy carried in fluid stream |
US8301264B2 (en) | 2008-04-25 | 2012-10-30 | Urologix, Inc. | Thermal therapy temperature sensor calibration method |
US8272383B2 (en) | 2008-05-06 | 2012-09-25 | Nxthera, Inc. | Systems and methods for male sterilization |
US8721632B2 (en) | 2008-09-09 | 2014-05-13 | Tsunami Medtech, Llc | Methods for delivering energy into a target tissue of a body |
JP2011522633A (ja) | 2008-06-06 | 2011-08-04 | バリックス・メディカル・コーポレイション | 血管治療装置および方法 |
US8932207B2 (en) | 2008-07-10 | 2015-01-13 | Covidien Lp | Integrated multi-functional endoscopic tool |
US10842555B2 (en) * | 2008-08-20 | 2020-11-24 | Prostacare Pty Ltd | Catheter for treating tissue with non-thermal ablation |
US9561068B2 (en) | 2008-10-06 | 2017-02-07 | Virender K. Sharma | Method and apparatus for tissue ablation |
US9561066B2 (en) | 2008-10-06 | 2017-02-07 | Virender K. Sharma | Method and apparatus for tissue ablation |
CN104739502B (zh) | 2008-10-06 | 2018-01-19 | 维兰德·K·沙马 | 用于组织消融的方法和装置 |
CA2742522C (en) | 2008-11-06 | 2019-02-12 | Michael Hoey | Systems and methods for treatment of prostatic tissue |
EP2352447A4 (en) * | 2008-11-06 | 2017-08-23 | Nxthera, Inc. | Systems and methods for treatment of bph |
WO2010054220A1 (en) | 2008-11-06 | 2010-05-14 | Nxthera, Inc. | Systems and methods for treatment of prostatic tissue |
US20110264176A1 (en) | 2008-11-18 | 2011-10-27 | Jerome Jackson | Hot tip vein therapy device |
US20100154419A1 (en) | 2008-12-19 | 2010-06-24 | E. I. Du Pont De Nemours And Company | Absorption power cycle system |
US20100179416A1 (en) | 2009-01-14 | 2010-07-15 | Michael Hoey | Medical Systems and Methods |
US8388611B2 (en) | 2009-01-14 | 2013-03-05 | Nxthera, Inc. | Systems and methods for treatment of prostatic tissue |
US11284931B2 (en) | 2009-02-03 | 2022-03-29 | Tsunami Medtech, Llc | Medical systems and methods for ablating and absorbing tissue |
US8517239B2 (en) | 2009-02-05 | 2013-08-27 | Ethicon Endo-Surgery, Inc. | Surgical stapling instrument comprising a magnetic element driver |
US8728068B2 (en) | 2009-04-09 | 2014-05-20 | Urologix, Inc. | Cooled antenna for device insertable into a body |
US20100298948A1 (en) | 2009-04-27 | 2010-11-25 | Michael Hoey | Systems and Methods for Prostate Treatment |
US9833277B2 (en) | 2009-04-27 | 2017-12-05 | Nxthera, Inc. | Systems and methods for prostate treatment |
CN101554498B (zh) * | 2009-05-21 | 2011-03-30 | 陈凯 | 一种用于动物连续注射的无针注射系统 |
CN101690834B (zh) * | 2009-10-29 | 2012-02-15 | 陈凯 | 电磁力驱动的连续无针注射系统 |
US8900223B2 (en) | 2009-11-06 | 2014-12-02 | Tsunami Medtech, Llc | Tissue ablation systems and methods of use |
US9161801B2 (en) | 2009-12-30 | 2015-10-20 | Tsunami Medtech, Llc | Medical system and method of use |
CN101803947B (zh) | 2010-03-11 | 2012-09-05 | 中国科学院理化技术研究所 | 一种用于肿瘤冷热联合治疗的冷热探针装置 |
EP2549963B1 (en) | 2010-03-25 | 2023-08-23 | Boston Scientific Scimed, Inc. | Systems for prostate treatment |
US9943353B2 (en) | 2013-03-15 | 2018-04-17 | Tsunami Medtech, Llc | Medical system and method of use |
WO2012075112A1 (en) | 2010-12-01 | 2012-06-07 | Enable Urology, Llc | Method and apparatus for remodeling/profiling a tissue lumen, particularly in the urethral lumen in the prostate gland |
JP6170037B2 (ja) | 2011-04-12 | 2017-07-26 | サーメディカル・インコーポレイテッド | アブレーション器具 |
JP6318088B2 (ja) | 2011-07-26 | 2018-04-25 | アンフォラ メディカル, インコーポレイテッド | 骨盤神経組織を変調するための装置および方法 |
US20130066308A1 (en) | 2011-08-31 | 2013-03-14 | Jaime Landman | Ablation-based therapy for bladder pathologies |
ES2656021T3 (es) * | 2011-09-13 | 2018-02-22 | Nxthera, Inc. | Sistemas de tratamiento de la próstata |
US9517083B2 (en) | 2011-09-16 | 2016-12-13 | Boston Scientific Scimed, Inc. | Apparatus for treating an organ and related methods of use |
US20130261692A1 (en) | 2012-03-27 | 2013-10-03 | Urologix Inc. | Neuromodulation system and related methods |
EP3777738A1 (en) * | 2012-04-03 | 2021-02-17 | Boston Scientific Scimed, Inc. | Induction coil vapor generator |
JP6374374B2 (ja) | 2012-04-22 | 2018-08-15 | オムリ ベン−エズラ, | 過活動膀胱障害に対する膀胱組織改変 |
EP2945556A4 (en) | 2013-01-17 | 2016-08-31 | Virender K Sharma | METHOD AND DEVICE FOR TISSUE REMOVAL |
JP2016513563A (ja) * | 2013-03-14 | 2016-05-16 | エヌエックスセラ インコーポレイテッド | 前立腺癌を治療するためのシステムおよび方法 |
WO2014150553A1 (en) | 2013-03-15 | 2014-09-25 | Boston Scientific Scimed, Inc. | Methods and apparatuses for remodeling tissue of or adjacent to a body passage |
US9390875B2 (en) | 2013-05-29 | 2016-07-12 | Active Signal Technologies, Inc. | Electromagnetic opposing field actuators |
WO2015073108A1 (en) * | 2013-11-13 | 2015-05-21 | Gyrus Acmi, Inc., D.B.A. Olympus Surgical Technologies America | Fibroid ablation positioning device and methods |
JP6422975B2 (ja) | 2013-12-10 | 2018-11-14 | エヌエックスセラ インコーポレイテッド | 蒸気焼灼システム及び方法 |
US9968395B2 (en) | 2013-12-10 | 2018-05-15 | Nxthera, Inc. | Systems and methods for treating the prostate |
CN107205770B (zh) * | 2015-01-29 | 2020-11-10 | 波士顿科学医学有限公司 | 蒸汽消融系统和方法 |
US10702327B2 (en) | 2015-05-13 | 2020-07-07 | Boston Scientific Scimed, Inc. | Systems and methods for treating the bladder with condensable vapor |
EP3389527B1 (en) | 2015-12-18 | 2023-09-13 | Nxthera, Inc. | Vapor ablation systems |
CN105944188B (zh) * | 2016-05-25 | 2020-03-13 | 张云鹤 | 磁动力助推器 |
-
2018
- 2018-01-08 AU AU2018205314A patent/AU2018205314B2/en active Active
- 2018-01-08 WO PCT/US2018/012815 patent/WO2018129466A1/en unknown
- 2018-01-08 EP EP24162910.4A patent/EP4356944A2/en active Pending
- 2018-01-08 CN CN201880006169.4A patent/CN110167473A/zh active Pending
- 2018-01-08 US US15/864,957 patent/US10751107B2/en active Active
- 2018-01-08 EP EP18736699.2A patent/EP3565493B1/en active Active
- 2018-01-08 JP JP2019536304A patent/JP7193463B2/ja active Active
-
2022
- 2022-12-08 JP JP2022196084A patent/JP7481418B2/ja active Active
-
2023
- 2023-09-12 AU AU2023229500A patent/AU2023229500A1/en active Pending
- 2023-11-03 US US18/501,235 patent/US20240074806A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP4356944A2 (en) | 2024-04-24 |
US20240074806A1 (en) | 2024-03-07 |
AU2018205314B2 (en) | 2023-06-15 |
AU2023229500A1 (en) | 2023-09-28 |
AU2018205314A1 (en) | 2019-07-18 |
JP7481418B2 (ja) | 2024-05-10 |
JP2020505093A (ja) | 2020-02-20 |
EP3565493B1 (en) | 2024-04-17 |
EP3565493A4 (en) | 2020-11-11 |
US20200397495A1 (en) | 2020-12-24 |
JP7193463B2 (ja) | 2022-12-20 |
US20180193080A1 (en) | 2018-07-12 |
US10751107B2 (en) | 2020-08-25 |
CN110167473A (zh) | 2019-08-23 |
EP3565493A1 (en) | 2019-11-13 |
WO2018129466A1 (en) | 2018-07-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP7193463B2 (ja) | 経腹膜蒸気焼灼システム及び方法 | |
US11583330B2 (en) | Devices and methods for remote temperature monitoring in fluid enhanced ablation therapy | |
EP1440665B1 (en) | Apparatus for therapeutic cauterization of predetermined volumes of biological tissue | |
US5947964A (en) | Methods and apparatus for therapeutic cauterization of predetermined volumes of biological tissue | |
US20240138901A1 (en) | Vapor ablation systems and methods | |
US6312428B1 (en) | Methods and apparatus for therapeutic cauterization of predetermined volumes of biological tissue | |
AU2017382873B2 (en) | Vapor ablation systems and methods | |
JP5909054B2 (ja) | 切除サイズを査定するためのエネルギーアプリケータ温度監視 | |
JP2009527331A (ja) | アブレーション器具および関連する方法 | |
SE532140C2 (sv) | Anordning för positionering av implanterbara ledningar | |
US11992254B2 (en) | Medical devices and methods |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20230105 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20230914 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20231212 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20240304 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20240401 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20240425 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 7481418 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |