JP2023022079A - アルカリ性化剤による血液浄化 - Google Patents

アルカリ性化剤による血液浄化 Download PDF

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JP2023022079A
JP2023022079A JP2022180930A JP2022180930A JP2023022079A JP 2023022079 A JP2023022079 A JP 2023022079A JP 2022180930 A JP2022180930 A JP 2022180930A JP 2022180930 A JP2022180930 A JP 2022180930A JP 2023022079 A JP2023022079 A JP 2023022079A
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Prior art keywords
pharmaceutical composition
concentration
alkalinizing agent
administration
day
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JP2022180930A
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English (en)
Japanese (ja)
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JP7525868B2 (ja
Inventor
倫明 阿部
Michiaki ABE
生造 小柴
Seizo Koshiba
浩一郎 西岡
Koichiro Nishioka
和彦 川口
Kazuhiko Kawaguchi
里美 山崎
Satomi Yamazaki
康行 寺中
Yasuyuki TERANAKA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tohoku University NUC
Nippon Chemiphar Co Ltd
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Tohoku University NUC
Nippon Chemiphar Co Ltd
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Priority claimed from JP2017085741A external-priority patent/JP7578234B2/ja
Priority claimed from JP2019513213A external-priority patent/JP7219898B2/ja
Application filed by Tohoku University NUC, Nippon Chemiphar Co Ltd filed Critical Tohoku University NUC
Publication of JP2023022079A publication Critical patent/JP2023022079A/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/194Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Mycology (AREA)
  • Pain & Pain Management (AREA)
  • Food Science & Technology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2022180930A 2017-04-18 2022-11-11 アルカリ性化剤による血液浄化 Active JP7525868B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP2017082423 2017-04-18
JP2017082423 2017-04-18
JP2017085741A JP7578234B2 (ja) 2017-04-18 2017-04-24 アルカリ性化剤による血液浄化
JP2017103935 2017-05-25
JP2017103935 2017-05-25
JP2019513213A JP7219898B2 (ja) 2017-04-18 2017-09-12 アルカリ性化剤による血液浄化
PCT/JP2017/032931 WO2018193648A1 (fr) 2017-04-18 2017-09-12 Procédé de purification du sang à l'aide d'un agent d'alcalinisation

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2019513213A Division JP7219898B2 (ja) 2017-04-18 2017-09-12 アルカリ性化剤による血液浄化

Publications (2)

Publication Number Publication Date
JP2023022079A true JP2023022079A (ja) 2023-02-14
JP7525868B2 JP7525868B2 (ja) 2024-07-31

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JP2022180930A Active JP7525868B2 (ja) 2017-04-18 2022-11-11 アルカリ性化剤による血液浄化

Country Status (4)

Country Link
JP (1) JP7525868B2 (fr)
KR (1) KR20240110103A (fr)
TW (1) TWI847827B (fr)
WO (2) WO2018193648A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019361520A1 (en) 2018-10-17 2021-05-20 Nippon Chemiphar Co., Ltd. Novel pharmaceutical composition
AU2019360846A1 (en) * 2018-10-17 2021-05-20 Kyoto Prefectural Public University Corporation Inhibitor of renal fibrosis in diabetic nephropathy
US20220202752A1 (en) 2019-04-28 2022-06-30 Tohoku University Novel pharmaceutical composition
KR20210013760A (ko) * 2019-07-18 2021-02-05 데루타-후라이 화마 가부시키가이샤 항암제의 효과 증강제
MX2022011722A (es) 2020-03-26 2023-02-22 Univ Tohoku Agente protector de la funcion renal.
TW202308604A (zh) * 2021-05-10 2023-03-01 國立大學法人東北大學 肌肉量增加用組成物

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1171287A (ja) * 1997-08-27 1999-03-16 Nisshin Flour Milling Co Ltd 猫慢性腎不全治療用組成物及びその治療方法
JP2007217366A (ja) * 2006-02-17 2007-08-30 Kirin Brewery Co Ltd 尿酸値降下用組成物
JP2009525276A (ja) * 2006-01-30 2009-07-09 グロボアジア エルエルシー 慢性腎疾患の治療法
WO2010126146A1 (fr) * 2009-04-30 2010-11-04 Tanaka Noriaki Procédé ou appareil pour déterminer la gravité des maladies rénales et procédé pour faire fonctionner ledit appareil
WO2011052765A1 (fr) * 2009-10-27 2011-05-05 味の素株式会社 Atténuateur de troubles rénaux provoqués par l'administration d'un médicament contenant du platine
WO2012005240A1 (fr) * 2010-07-05 2012-01-12 株式会社明治 Bifidobactérium possédant une activité de réduction de la quantité de substance putréfiée intestinale
WO2016153331A1 (fr) * 2015-03-20 2016-09-29 Hernández Miramontes Jorge Antonio Mélange d'acides carboxyliques pour traiter des patients avec une insuffisance rénale
JP2016191707A (ja) * 2015-03-30 2016-11-10 株式会社バイオマーカーサイエンス インドキシル硫酸の測定方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60105619A (ja) * 1983-11-15 1985-06-11 Nippon Chemiphar Co Ltd 尿アルカリ化性食品組成物
JPS60197624A (ja) * 1984-03-21 1985-10-07 Nippon Chemiphar Co Ltd 尿アルカリ化性食品組成物
JP2017082423A (ja) 2015-10-23 2017-05-18 信越ポリマー株式会社 トリム部材、及び該トリム部材を用いた施工方法
JP2017085741A (ja) 2015-10-27 2017-05-18 住友電装株式会社 ワイヤハーネスの外装材
JP2017103935A (ja) 2015-12-02 2017-06-08 田淵電機株式会社 分散型電源のシステム制御装置、及びパワーコンディショナ

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1171287A (ja) * 1997-08-27 1999-03-16 Nisshin Flour Milling Co Ltd 猫慢性腎不全治療用組成物及びその治療方法
JP2009525276A (ja) * 2006-01-30 2009-07-09 グロボアジア エルエルシー 慢性腎疾患の治療法
JP2007217366A (ja) * 2006-02-17 2007-08-30 Kirin Brewery Co Ltd 尿酸値降下用組成物
WO2010126146A1 (fr) * 2009-04-30 2010-11-04 Tanaka Noriaki Procédé ou appareil pour déterminer la gravité des maladies rénales et procédé pour faire fonctionner ledit appareil
WO2011052765A1 (fr) * 2009-10-27 2011-05-05 味の素株式会社 Atténuateur de troubles rénaux provoqués par l'administration d'un médicament contenant du platine
WO2012005240A1 (fr) * 2010-07-05 2012-01-12 株式会社明治 Bifidobactérium possédant une activité de réduction de la quantité de substance putréfiée intestinale
WO2016153331A1 (fr) * 2015-03-20 2016-09-29 Hernández Miramontes Jorge Antonio Mélange d'acides carboxyliques pour traiter des patients avec une insuffisance rénale
JP2016191707A (ja) * 2015-03-30 2016-11-10 株式会社バイオマーカーサイエンス インドキシル硫酸の測定方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SOROT PHISITKUL ET AL.: "Amelioration of metabolic acidosis in patients with low GFR reduced kidney endothelin production and", KIDNEY INTERNATIONAL, vol. 77, no. 7, JPN6022036650, 13 January 2010 (2010-01-13), pages 617 - 623, XP055751794, ISSN: 0005201523, DOI: 10.1038/ki.2009.519 *
阿部倫明, 2012年度実績報告書 腎尿細管液の酸性化とアルブミン尿による腎障害機序の解明と新規腎臓病治療戦略の開発, JPN6018021568, 2014, ISSN: 0005201522 *

Also Published As

Publication number Publication date
TWI847827B (zh) 2024-07-01
TW202345784A (zh) 2023-12-01
KR20240110103A (ko) 2024-07-12
WO2018193648A1 (fr) 2018-10-25
WO2018193752A1 (fr) 2018-10-25
JP7525868B2 (ja) 2024-07-31

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