JP2023011898A5 - - Google Patents
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- Publication number
- JP2023011898A5 JP2023011898A5 JP2022178888A JP2022178888A JP2023011898A5 JP 2023011898 A5 JP2023011898 A5 JP 2023011898A5 JP 2022178888 A JP2022178888 A JP 2022178888A JP 2022178888 A JP2022178888 A JP 2022178888A JP 2023011898 A5 JP2023011898 A5 JP 2023011898A5
- Authority
- JP
- Japan
- Prior art keywords
- aqueous suspension
- nonionic surfactant
- zinc
- trifluoromethylchroman
- tetrahydronaphthalen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007900 aqueous suspension Substances 0.000 claims 15
- 239000002736 nonionic surfactant Substances 0.000 claims 5
- MAWBBYZCTDJMDD-GXDHUFHOSA-N (2e)-n-(7-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)-2-[7-(trifluoromethyl)-2,3-dihydrochromen-4-ylidene]acetamide Chemical compound C\1COC2=CC(C(F)(F)F)=CC=C2C/1=C/C(=O)NC1=C(CC(O)CC2)C2=CC=C1 MAWBBYZCTDJMDD-GXDHUFHOSA-N 0.000 claims 3
- GGCZERPQGJTIQP-UHFFFAOYSA-N sodium;9,10-dioxoanthracene-2-sulfonic acid Chemical compound [Na+].C1=CC=C2C(=O)C3=CC(S(=O)(=O)O)=CC=C3C(=O)C2=C1 GGCZERPQGJTIQP-UHFFFAOYSA-N 0.000 claims 3
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- SQGYOTSLMSWVJD-UHFFFAOYSA-N silver(1+) nitrate Chemical group [Ag+].[O-]N(=O)=O SQGYOTSLMSWVJD-UHFFFAOYSA-N 0.000 claims 2
- 239000012453 solvate Substances 0.000 claims 2
- 239000011701 zinc Substances 0.000 claims 2
- 229910052725 zinc Inorganic materials 0.000 claims 2
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical group [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 claims 2
- RFVNOJDQRGSOEL-UHFFFAOYSA-N 2-hydroxyethyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCO RFVNOJDQRGSOEL-UHFFFAOYSA-N 0.000 claims 1
- BTBUEUYNUDRHOZ-UHFFFAOYSA-N Borate Chemical compound [O-]B([O-])[O-] BTBUEUYNUDRHOZ-UHFFFAOYSA-N 0.000 claims 1
- MAWBBYZCTDJMDD-HFQYIWAZSA-N FC(C1=CC=C2\C(\CCOC2=C1)=C\C(=O)NC1=CC=CC=2CC[C@H](CC1=2)O)(F)F Chemical group FC(C1=CC=C2\C(\CCOC2=C1)=C\C(=O)NC1=CC=CC=2CC[C@H](CC1=2)O)(F)F MAWBBYZCTDJMDD-HFQYIWAZSA-N 0.000 claims 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- 239000004359 castor oil Substances 0.000 claims 1
- 235000019438 castor oil Nutrition 0.000 claims 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- -1 polyoxyethylene Polymers 0.000 claims 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 claims 1
- 229920000053 polysorbate 80 Polymers 0.000 claims 1
- 229940068968 polysorbate 80 Drugs 0.000 claims 1
- 229910001961 silver nitrate Inorganic materials 0.000 claims 1
- 229920001664 tyloxapol Polymers 0.000 claims 1
- MDYZKJNTKZIUSK-UHFFFAOYSA-N tyloxapol Chemical compound O=C.C1CO1.CC(C)(C)CC(C)(C)C1=CC=C(O)C=C1 MDYZKJNTKZIUSK-UHFFFAOYSA-N 0.000 claims 1
- 229960004224 tyloxapol Drugs 0.000 claims 1
- 150000003751 zinc Chemical class 0.000 claims 1
- 235000005074 zinc chloride Nutrition 0.000 claims 1
- 239000011592 zinc chloride Substances 0.000 claims 1
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 claims 1
- 229960001763 zinc sulfate Drugs 0.000 claims 1
- 229910000368 zinc sulfate Inorganic materials 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023073689A JP2023099107A (ja) | 2021-03-30 | 2023-04-27 | ヘテロシクリデンアセトアミド誘導体含有懸濁液 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021057713 | 2021-03-30 | ||
| JP2021057713 | 2021-03-30 | ||
| JP2022546133A JP7175431B1 (ja) | 2021-03-30 | 2022-03-29 | ヘテロシクリデンアセトアミド誘導体含有懸濁液 |
| PCT/JP2022/015691 WO2022210784A1 (ja) | 2021-03-30 | 2022-03-29 | ヘテロシクリデンアセトアミド誘導体含有懸濁液 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022546133A Division JP7175431B1 (ja) | 2021-03-30 | 2022-03-29 | ヘテロシクリデンアセトアミド誘導体含有懸濁液 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023073689A Division JP2023099107A (ja) | 2021-03-30 | 2023-04-27 | ヘテロシクリデンアセトアミド誘導体含有懸濁液 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023011898A JP2023011898A (ja) | 2023-01-24 |
| JP2023011898A5 true JP2023011898A5 (https=) | 2023-01-31 |
| JP7273235B2 JP7273235B2 (ja) | 2023-05-12 |
Family
ID=83459508
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022546133A Active JP7175431B1 (ja) | 2021-03-30 | 2022-03-29 | ヘテロシクリデンアセトアミド誘導体含有懸濁液 |
| JP2022178888A Active JP7273235B2 (ja) | 2021-03-30 | 2022-11-08 | ヘテロシクリデンアセトアミド誘導体含有懸濁液 |
| JP2023073689A Pending JP2023099107A (ja) | 2021-03-30 | 2023-04-27 | ヘテロシクリデンアセトアミド誘導体含有懸濁液 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022546133A Active JP7175431B1 (ja) | 2021-03-30 | 2022-03-29 | ヘテロシクリデンアセトアミド誘導体含有懸濁液 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023073689A Pending JP2023099107A (ja) | 2021-03-30 | 2023-04-27 | ヘテロシクリデンアセトアミド誘導体含有懸濁液 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US12564553B2 (https=) |
| EP (1) | EP4316485A4 (https=) |
| JP (3) | JP7175431B1 (https=) |
| KR (1) | KR20230163502A (https=) |
| CN (1) | CN117120048A (https=) |
| AU (1) | AU2022250028A1 (https=) |
| BR (1) | BR112023019820A2 (https=) |
| CA (1) | CA3215750A1 (https=) |
| MX (1) | MX2023011649A (https=) |
| WO (1) | WO2022210784A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2024019118A1 (https=) | 2022-07-20 | 2024-01-25 | ||
| WO2025206172A1 (ja) * | 2024-03-28 | 2025-10-02 | 千寿製薬株式会社 | 電子線滅菌処理したヘテロシクリデンアセトアミド誘導体含有組成物 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61164725A (ja) | 1985-01-11 | 1986-07-25 | Inoue Japax Res Inc | ワイヤ電極案内 |
| JPH07304663A (ja) * | 1994-03-18 | 1995-11-21 | Senju Pharmaceut Co Ltd | 眼圧降下用点眼剤 |
| ATE166227T1 (de) | 1994-03-18 | 1998-06-15 | Senju Pharma Co | Sarpogrelat enthaltende opthalmologische zubereitungen zur senkung des intraokularen druckes |
| JP3402195B2 (ja) * | 1997-05-14 | 2003-04-28 | 千寿製薬株式会社 | 再分散性の良い水性懸濁液剤 |
| EP0995435B1 (en) * | 1997-05-14 | 2007-04-25 | Senju Pharmaceutical Co., Ltd. | Aqueous suspension preparations with excellent redispersibility |
| JP4754566B2 (ja) | 2005-07-22 | 2011-08-24 | 持田製薬株式会社 | 新規なヘテロシクリデンアセトアミド誘導体 |
| WO2008123396A1 (ja) | 2007-03-29 | 2008-10-16 | Santen Pharmaceutical Co., Ltd. | フルオロメトロンを含有する懸濁型点眼剤 |
| ES2493641T3 (es) * | 2007-06-28 | 2014-09-12 | Cydex Pharmaceuticals, Inc. | Administración nasal de soluciones acuosas de corticosteroides |
| JP6230743B1 (ja) * | 2017-05-31 | 2017-11-15 | 持田製薬株式会社 | ヘテロシクリデンアセトアミド誘導体の結晶 |
| WO2021039023A1 (ja) | 2019-08-23 | 2021-03-04 | 持田製薬株式会社 | ヘテロシクリデンアセトアミド誘導体の製造方法 |
| CN112409191A (zh) | 2019-08-23 | 2021-02-26 | 持田制药株式会社 | 光学活性的氨基醇的制备方法 |
| KR102656181B1 (ko) * | 2019-08-27 | 2024-04-08 | 산텐 세이야꾸 가부시키가이샤 | 디쿠아포솔 또는 그 염 및 폴리비닐피롤리돈을 함유하는 수성 안과용 조성물 |
| JP7419728B2 (ja) | 2019-09-27 | 2024-01-23 | ブラザー工業株式会社 | 通信装置と通信装置のためのコンピュータプログラム |
| CA3156484A1 (en) | 2019-10-04 | 2021-04-08 | Senju Pharmaceutical Co., Ltd. | PHARMACEUTICAL MEDICINAL PRODUCT CONTAINING A HETEROCYCLIDENE ACETAMIDE DERIVATIVE |
-
2022
- 2022-03-29 CN CN202280026310.3A patent/CN117120048A/zh active Pending
- 2022-03-29 US US18/553,141 patent/US12564553B2/en active Active
- 2022-03-29 EP EP22780995.1A patent/EP4316485A4/en active Pending
- 2022-03-29 BR BR112023019820A patent/BR112023019820A2/pt unknown
- 2022-03-29 AU AU2022250028A patent/AU2022250028A1/en active Pending
- 2022-03-29 WO PCT/JP2022/015691 patent/WO2022210784A1/ja not_active Ceased
- 2022-03-29 KR KR1020237037161A patent/KR20230163502A/ko active Pending
- 2022-03-29 JP JP2022546133A patent/JP7175431B1/ja active Active
- 2022-03-29 CA CA3215750A patent/CA3215750A1/en active Pending
- 2022-03-29 MX MX2023011649A patent/MX2023011649A/es unknown
- 2022-11-08 JP JP2022178888A patent/JP7273235B2/ja active Active
-
2023
- 2023-04-27 JP JP2023073689A patent/JP2023099107A/ja active Pending
-
2025
- 2025-01-03 US US19/009,331 patent/US12527740B2/en active Active
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