JP2022553862A - 活性剤投与用胃内滞留型システム - Google Patents

活性剤投与用胃内滞留型システム Download PDF

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Publication number
JP2022553862A
JP2022553862A JP2022526215A JP2022526215A JP2022553862A JP 2022553862 A JP2022553862 A JP 2022553862A JP 2022526215 A JP2022526215 A JP 2022526215A JP 2022526215 A JP2022526215 A JP 2022526215A JP 2022553862 A JP2022553862 A JP 2022553862A
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Japan
Prior art keywords
gastric retention
retention system
arm
linker
plga
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JP2022526215A
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English (en)
Japanese (ja)
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JP2022553862A5 (OSRAM
Inventor
カナスティー ローズマリー
グラント タイラー
オルトルーター デイビッド
ウェイト アリシャ
ムアシー ソームヤ
タイ タミー
ジャラミロ モンテスコ ジュアン
シュワルツ マーリーン
フン ヤン チュン
トラン ジーン
ドゥアン ミッシェル
チン チエ
シー．デュフォア デイビッド
ロバート ワルデマー ライド エリック
ビース ヌプラ
デ ラ トール ニコラス
ホラー ソニア
ベギン エステレ
シムセス クレイグ
ピーク エリック
レイ エリカ
Original Assignee
リンドラ セラピューティクス， インコーポレイティド
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Publication of JP2022553862A publication Critical patent/JP2022553862A/ja
Publication of JP2022553862A5 publication Critical patent/JP2022553862A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2022526215A 2019-11-08 2020-11-06 活性剤投与用胃内滞留型システム Pending JP2022553862A (ja)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US201962933210P 2019-11-08 2019-11-08
US201962933313P 2019-11-08 2019-11-08
US201962933211P 2019-11-08 2019-11-08
US201962933348P 2019-11-08 2019-11-08
US201962933226P 2019-11-08 2019-11-08
US62/933,348 2019-11-08
US62/933,226 2019-11-08
US62/933,313 2019-11-08
US62/933,211 2019-11-08
US62/933,210 2019-11-08
US202062992075P 2020-03-19 2020-03-19
US62/992,075 2020-03-19
US202063052905P 2020-07-16 2020-07-16
US63/052,905 2020-07-16
PCT/US2020/059541 WO2021092491A1 (en) 2019-11-08 2020-11-06 Gastric residence systems for administration of active agents

Publications (2)

Publication Number Publication Date
JP2022553862A true JP2022553862A (ja) 2022-12-26
JP2022553862A5 JP2022553862A5 (OSRAM) 2023-11-14

Family

ID=75849597

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022526215A Pending JP2022553862A (ja) 2019-11-08 2020-11-06 活性剤投与用胃内滞留型システム

Country Status (10)

Country Link
US (1) US20220387311A1 (OSRAM)
EP (1) EP4054545A4 (OSRAM)
JP (1) JP2022553862A (OSRAM)
CN (1) CN115003335A (OSRAM)
AU (1) AU2020378438A1 (OSRAM)
BR (1) BR112022008908A2 (OSRAM)
CA (1) CA3160665A1 (OSRAM)
IL (1) IL292849A (OSRAM)
MX (1) MX2022005494A (OSRAM)
WO (1) WO2021092491A1 (OSRAM)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12142158B2 (en) 2018-12-03 2024-11-12 Lyndra Therapeutics, Inc. Stomach simulating device
CA3134186A1 (en) 2019-03-20 2020-09-24 Lyndra Therapeutics, Inc. Coatings for gastric residence dosage forms
US12447130B2 (en) 2019-03-20 2025-10-21 Lyndra Therapeutics, Inc. Capsules and capsule coatings for gastric residence dosage forms
US12144894B2 (en) 2020-07-29 2024-11-19 The Secant Group, Llc Shape-guided controlled release and retention with structures including crosslinked poly(glycerol sebacate)
CA3173792A1 (en) * 2021-01-19 2022-07-28 Rosemary KANASTY Gastric residence systems for administration of risperidone
EP4465964A4 (en) * 2022-01-19 2026-01-07 Lyndra Therapeutics Inc Pharmaceutical forms for gastric retention
CN115227879B (zh) * 2022-09-15 2023-01-06 北京天星博迈迪医疗器械有限公司 一种用于可降解关节球囊的组合物及其应用、一种可降解关节球囊及其制备方法
EP4719179A2 (en) * 2023-06-02 2026-04-08 Nortiva Bio, Inc. Manufacturing methods for gastric residence systems
WO2025042350A1 (en) * 2023-08-24 2025-02-27 Junion Therapeutics (Xiamen) Co., Ltd. A gastric residence article for oral administration
WO2025042349A1 (en) * 2023-08-24 2025-02-27 Junion Therapeutics (Xiamen) Co., Ltd. A gastric residence article for oral administration
WO2025148850A1 (zh) * 2024-01-09 2025-07-17 厦门君德医药科技有限公司 一种胃滞留装置
WO2025153071A1 (en) * 2024-01-18 2025-07-24 Junion Therapeutics (Xiamen) Co., Ltd. Gastric residence article for oral administration
CN120154807B (zh) * 2024-03-22 2025-11-21 厦门君德医药科技有限公司 一种胃滞留装置

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018064630A1 (en) * 2016-09-30 2018-04-05 Lyndra, Inc. Gastric residence systems for sustained delivery of adamantane-class drugs
JP2019503347A (ja) * 2015-12-08 2019-02-07 リンドラ，インコーポレイティド 胃滞留システムのための幾何学的構成
JP2022526233A (ja) * 2019-03-25 2022-05-24 ダグラス ファーマシューティカルズ エルティーディー． 持続放出性の医薬製剤

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GB9925962D0 (en) * 1999-11-02 1999-12-29 Novartis Ag Organic compounds
AU2007207618B2 (en) * 2006-01-18 2011-03-24 Foresee Pharmaceuticals Co., Ltd. Pharmaceutical compositions with enhanced stability
ES2368356T3 (es) * 2007-07-06 2011-11-16 Basf Corporation Composición de retención gástrica basada en un producto de reacción hidrosoluble procedente de un precursor que contiene un grupo vinilo.
EP2555756B1 (en) * 2010-04-07 2018-08-22 Lupin Limited Controlled release pharmaceutical compositions of tapentadol
EP3482776B1 (en) * 2010-08-06 2020-07-15 Endoshape, Inc. Radiopaque shape memory polymers for medical devices
RU2766335C2 (ru) * 2014-06-11 2022-03-15 Массачусетс Инститьют Оф Текнолоджи Удерживаемые структуры и связанные способы
CN108472249A (zh) * 2015-10-23 2018-08-31 林德拉有限公司 用于治疗剂缓释的胃驻留系统及其使用方法
CN109310639A (zh) * 2016-05-27 2019-02-05 林德拉有限公司 用于胃驻留系统的材料结构
EP3634382A4 (en) * 2017-06-09 2021-07-07 Lyndra Therapeutics, Inc. STOMACHING SYSTEMS WITH RELEASE RATE MODULATING FILMS
WO2019060458A1 (en) * 2017-09-20 2019-03-28 Lyndra, Inc. ENCAPSULATION OF GASTRIC SYSTEMS

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019503347A (ja) * 2015-12-08 2019-02-07 リンドラ，インコーポレイティド 胃滞留システムのための幾何学的構成
WO2018064630A1 (en) * 2016-09-30 2018-04-05 Lyndra, Inc. Gastric residence systems for sustained delivery of adamantane-class drugs
JP2022526233A (ja) * 2019-03-25 2022-05-24 ダグラス ファーマシューティカルズ エルティーディー． 持続放出性の医薬製剤

Also Published As

Publication number Publication date
CN115003335A (zh) 2022-09-02
AU2020378438A1 (en) 2022-06-02
WO2021092491A1 (en) 2021-05-14
MX2022005494A (es) 2022-08-11
EP4054545A1 (en) 2022-09-14
BR112022008908A2 (pt) 2022-10-11
US20220387311A1 (en) 2022-12-08
CA3160665A1 (en) 2021-05-14
IL292849A (en) 2022-07-01
EP4054545A4 (en) 2024-02-14

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