MX2022005494A - Sistemas de residencia gastrica para la administracion de agentes activos. - Google Patents

Sistemas de residencia gastrica para la administracion de agentes activos.

Info

Publication number
MX2022005494A
MX2022005494A MX2022005494A MX2022005494A MX2022005494A MX 2022005494 A MX2022005494 A MX 2022005494A MX 2022005494 A MX2022005494 A MX 2022005494A MX 2022005494 A MX2022005494 A MX 2022005494A MX 2022005494 A MX2022005494 A MX 2022005494A
Authority
MX
Mexico
Prior art keywords
gastric residence
disclosed
administration
gastric
active agents
Prior art date
Application number
MX2022005494A
Other languages
English (en)
Inventor
Tyler Grant
Rosemary Kanasty
Jeanne Tran
Erick Peeke
David Altreuter
Marlene Schwarz
Sonia Holar
Alisha Weight
Saumya Moorthy
Tammy Tai
Juan Jaramillo Montezco
Jung Hoon Yang
Michelle Duan
Jie Jing
David C Dufour
Erik Robert Waldemar Ryde
Nupura Bhise
La Torre Nicholas De
Estelle Beguin
Craig Simses
Erica Lai
Original Assignee
Lyndra Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lyndra Therapeutics Inc filed Critical Lyndra Therapeutics Inc
Publication of MX2022005494A publication Critical patent/MX2022005494A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se describen sistemas de residencia gástrica para la administración de agentes, tales como fármacos. Se describen características que mejoran la retención gástrica durante el tiempo de residencia deseado y que permiten un control más preciso sobre el tiempo de residencia, que incluyen filamentos circunferenciales que conectan los brazos de un sistema de residencia gástrica estrellado; brazos flexibles para un sistema de residencia gástrica; matrices de desintegración entéricas y dependientes del tiempo mejoradas (conectores); y recubrimientos poliméricos moduladores de la velocidad de liberación que son resistentes al cambio en las propiedades de la velocidad de liberación durante el montaje asistido por calor o ciclos térmicos. También se describen combinaciones de estas características.
MX2022005494A 2019-11-08 2020-11-06 Sistemas de residencia gastrica para la administracion de agentes activos. MX2022005494A (es)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201962933210P 2019-11-08 2019-11-08
US201962933348P 2019-11-08 2019-11-08
US201962933226P 2019-11-08 2019-11-08
US201962933313P 2019-11-08 2019-11-08
US201962933211P 2019-11-08 2019-11-08
US202062992075P 2020-03-19 2020-03-19
US202063052905P 2020-07-16 2020-07-16
PCT/US2020/059541 WO2021092491A1 (en) 2019-11-08 2020-11-06 Gastric residence systems for administration of active agents

Publications (1)

Publication Number Publication Date
MX2022005494A true MX2022005494A (es) 2022-08-11

Family

ID=75849597

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022005494A MX2022005494A (es) 2019-11-08 2020-11-06 Sistemas de residencia gastrica para la administracion de agentes activos.

Country Status (10)

Country Link
US (1) US20220387311A1 (es)
EP (1) EP4054545A4 (es)
JP (1) JP2022553862A (es)
CN (1) CN115003335A (es)
AU (1) AU2020378438A1 (es)
BR (1) BR112022008908A2 (es)
CA (1) CA3160665A1 (es)
IL (1) IL292849A (es)
MX (1) MX2022005494A (es)
WO (1) WO2021092491A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022159529A1 (en) * 2021-01-19 2022-07-28 Lyndra Therapeutics, Inc. Gastric residence systems for administration of risperidone

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007084460A2 (en) * 2006-01-18 2007-07-26 Qps, Llc Pharmaceutical compositions with enhanced stability
WO2012019145A1 (en) * 2010-08-06 2012-02-09 Endoshape, Inc. Radiopaque shape memory polymers for medical devices
AU2016342374B2 (en) * 2015-10-23 2022-08-04 Lyndra Therapeutics, Inc. Gastric residence systems for sustained release of therapeutic agents and methods of use thereof
WO2017100367A1 (en) * 2015-12-08 2017-06-15 Lyndra, Inc. Geometric configurations for gastric residence systems
CA3025650A1 (en) * 2016-05-27 2017-11-30 Lyndra, Inc. Materials architecture for gastric residence systems
WO2018064630A1 (en) * 2016-09-30 2018-04-05 Lyndra, Inc. Gastric residence systems for sustained delivery of adamantane-class drugs
WO2018227147A1 (en) * 2017-06-09 2018-12-13 Lyndra, Inc. Gastric residence systems with release rate-modulating films
WO2019060458A1 (en) * 2017-09-20 2019-03-28 Lyndra, Inc. ENCAPSULATION OF GASTRIC SYSTEMS

Also Published As

Publication number Publication date
BR112022008908A2 (pt) 2022-10-11
US20220387311A1 (en) 2022-12-08
AU2020378438A1 (en) 2022-06-02
CA3160665A1 (en) 2021-05-14
WO2021092491A1 (en) 2021-05-14
JP2022553862A (ja) 2022-12-26
IL292849A (en) 2022-07-01
EP4054545A4 (en) 2024-02-14
CN115003335A (zh) 2022-09-02
EP4054545A1 (en) 2022-09-14

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