BR112022008908A2 - Sistemas de permanência gástrica para administração de agentes ativos - Google Patents
Sistemas de permanência gástrica para administração de agentes ativosInfo
- Publication number
- BR112022008908A2 BR112022008908A2 BR112022008908A BR112022008908A BR112022008908A2 BR 112022008908 A2 BR112022008908 A2 BR 112022008908A2 BR 112022008908 A BR112022008908 A BR 112022008908A BR 112022008908 A BR112022008908 A BR 112022008908A BR 112022008908 A2 BR112022008908 A2 BR 112022008908A2
- Authority
- BR
- Brazil
- Prior art keywords
- gastric
- systems
- disclosed
- permanence
- active agents
- Prior art date
Links
- 230000002496 gastric effect Effects 0.000 title abstract 6
- 239000013543 active substance Substances 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 230000014759 maintenance of location Effects 0.000 abstract 1
- 238000005382 thermal cycling Methods 0.000 abstract 1
- 230000036962 time dependent Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SISTEMAS DE PERMANÊNCIA GÁSTRICA PARA ADMINISTRAÇÃO DE AGENTES ATIVOS. Sistemas de residência gástrica para administração de agentes, tais como drogas, são divulgados. São divulgadas características que aumentam a retenção gástrica durante o tempo de residência desejado e que permitem um controle mais preciso sobre o tempo de residência, incluindo filamentos circunferenciais que conectam os braços de um sistema de residência gástrico estrelado; braços flexíveis para sistema de residência gástrica; matrizes de desintegração entérica e dependentes do tempo melhoradas (ligantes); e revestimentos poliméricos moduladores da taxa de liberação que são resistentes à mudança nas propriedades da taxa de liberação durante a montagem assistida por calor ou ciclo térmico. Combinações dessas características também são divulgadas.
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962933226P | 2019-11-08 | 2019-11-08 | |
US201962933211P | 2019-11-08 | 2019-11-08 | |
US201962933210P | 2019-11-08 | 2019-11-08 | |
US201962933313P | 2019-11-08 | 2019-11-08 | |
US201962933348P | 2019-11-08 | 2019-11-08 | |
US202062992075P | 2020-03-19 | 2020-03-19 | |
US202063052905P | 2020-07-16 | 2020-07-16 | |
PCT/US2020/059541 WO2021092491A1 (en) | 2019-11-08 | 2020-11-06 | Gastric residence systems for administration of active agents |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112022008908A2 true BR112022008908A2 (pt) | 2022-10-11 |
Family
ID=75849597
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112022008908A BR112022008908A2 (pt) | 2019-11-08 | 2020-11-06 | Sistemas de permanência gástrica para administração de agentes ativos |
Country Status (10)
Country | Link |
---|---|
US (1) | US20220387311A1 (pt) |
EP (1) | EP4054545A4 (pt) |
JP (1) | JP2022553862A (pt) |
CN (1) | CN115003335A (pt) |
AU (1) | AU2020378438A1 (pt) |
BR (1) | BR112022008908A2 (pt) |
CA (1) | CA3160665A1 (pt) |
IL (1) | IL292849A (pt) |
MX (1) | MX2022005494A (pt) |
WO (1) | WO2021092491A1 (pt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2022159529A1 (en) * | 2021-01-19 | 2022-07-28 | Lyndra Therapeutics, Inc. | Gastric residence systems for administration of risperidone |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101728868B1 (ko) * | 2006-01-18 | 2017-05-02 | 포시 파마슈티컬스 컴퍼니 리미티드 | 안정성이 강화된 약학 조성물 |
EP2600902A4 (en) * | 2010-08-06 | 2015-01-07 | Endoshape Inc | X-RAY DENSITY RESIN POLYMERS FOR MEDICAL DEVICES |
CN108472249A (zh) * | 2015-10-23 | 2018-08-31 | 林德拉有限公司 | 用于治疗剂缓释的胃驻留系统及其使用方法 |
CA3025650A1 (en) * | 2016-05-27 | 2017-11-30 | Lyndra, Inc. | Materials architecture for gastric residence systems |
CN110022861A (zh) * | 2016-09-30 | 2019-07-16 | 林德拉有限公司 | 用于金刚烷类药物缓释的胃驻留系统 |
CN110996906A (zh) * | 2017-06-09 | 2020-04-10 | 林德拉有限公司 | 具有调节释放速度的膜的胃驻留系统 |
US11793751B2 (en) * | 2017-09-20 | 2023-10-24 | Lyndra Therapeutics, Inc. | Encapsulation of gastric residence systems |
-
2020
- 2020-11-06 CA CA3160665A patent/CA3160665A1/en active Pending
- 2020-11-06 EP EP20884024.9A patent/EP4054545A4/en active Pending
- 2020-11-06 BR BR112022008908A patent/BR112022008908A2/pt not_active Application Discontinuation
- 2020-11-06 US US17/774,132 patent/US20220387311A1/en active Pending
- 2020-11-06 JP JP2022526215A patent/JP2022553862A/ja active Pending
- 2020-11-06 CN CN202080092586.2A patent/CN115003335A/zh active Pending
- 2020-11-06 MX MX2022005494A patent/MX2022005494A/es unknown
- 2020-11-06 AU AU2020378438A patent/AU2020378438A1/en active Pending
- 2020-11-06 WO PCT/US2020/059541 patent/WO2021092491A1/en unknown
-
2022
- 2022-05-08 IL IL292849A patent/IL292849A/en unknown
Also Published As
Publication number | Publication date |
---|---|
MX2022005494A (es) | 2022-08-11 |
US20220387311A1 (en) | 2022-12-08 |
EP4054545A1 (en) | 2022-09-14 |
CN115003335A (zh) | 2022-09-02 |
EP4054545A4 (en) | 2024-02-14 |
CA3160665A1 (en) | 2021-05-14 |
IL292849A (en) | 2022-07-01 |
JP2022553862A (ja) | 2022-12-26 |
AU2020378438A1 (en) | 2022-06-02 |
WO2021092491A1 (en) | 2021-05-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B04C | Request for examination: application reinstated [chapter 4.3 patent gazette] |