IL292849A - A gastric retention system for administering active substances - Google Patents

A gastric retention system for administering active substances

Info

Publication number
IL292849A
IL292849A IL292849A IL29284922A IL292849A IL 292849 A IL292849 A IL 292849A IL 292849 A IL292849 A IL 292849A IL 29284922 A IL29284922 A IL 29284922A IL 292849 A IL292849 A IL 292849A
Authority
IL
Israel
Prior art keywords
administration
active agents
gastric residence
residence systems
systems
Prior art date
Application number
IL292849A
Other languages
English (en)
Hebrew (he)
Original Assignee
Lyndra Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lyndra Therapeutics Inc filed Critical Lyndra Therapeutics Inc
Publication of IL292849A publication Critical patent/IL292849A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL292849A 2019-11-08 2022-05-08 A gastric retention system for administering active substances IL292849A (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201962933211P 2019-11-08 2019-11-08
US201962933210P 2019-11-08 2019-11-08
US201962933313P 2019-11-08 2019-11-08
US201962933348P 2019-11-08 2019-11-08
US201962933226P 2019-11-08 2019-11-08
US202062992075P 2020-03-19 2020-03-19
US202063052905P 2020-07-16 2020-07-16
PCT/US2020/059541 WO2021092491A1 (en) 2019-11-08 2020-11-06 Gastric residence systems for administration of active agents

Publications (1)

Publication Number Publication Date
IL292849A true IL292849A (en) 2022-07-01

Family

ID=75849597

Family Applications (1)

Application Number Title Priority Date Filing Date
IL292849A IL292849A (en) 2019-11-08 2022-05-08 A gastric retention system for administering active substances

Country Status (10)

Country Link
US (1) US20220387311A1 (OSRAM)
EP (1) EP4054545A4 (OSRAM)
JP (1) JP2022553862A (OSRAM)
CN (1) CN115003335A (OSRAM)
AU (1) AU2020378438A1 (OSRAM)
BR (1) BR112022008908A2 (OSRAM)
CA (1) CA3160665A1 (OSRAM)
IL (1) IL292849A (OSRAM)
MX (1) MX2022005494A (OSRAM)
WO (1) WO2021092491A1 (OSRAM)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12142158B2 (en) 2018-12-03 2024-11-12 Lyndra Therapeutics, Inc. Stomach simulating device
CA3134186A1 (en) 2019-03-20 2020-09-24 Lyndra Therapeutics, Inc. Coatings for gastric residence dosage forms
US12447130B2 (en) 2019-03-20 2025-10-21 Lyndra Therapeutics, Inc. Capsules and capsule coatings for gastric residence dosage forms
US12144894B2 (en) 2020-07-29 2024-11-19 The Secant Group, Llc Shape-guided controlled release and retention with structures including crosslinked poly(glycerol sebacate)
CA3173792A1 (en) * 2021-01-19 2022-07-28 Rosemary KANASTY Gastric residence systems for administration of risperidone
EP4465964A4 (en) * 2022-01-19 2026-01-07 Lyndra Therapeutics Inc Pharmaceutical forms for gastric retention
CN115227879B (zh) * 2022-09-15 2023-01-06 北京天星博迈迪医疗器械有限公司 一种用于可降解关节球囊的组合物及其应用、一种可降解关节球囊及其制备方法
EP4719179A2 (en) * 2023-06-02 2026-04-08 Nortiva Bio, Inc. Manufacturing methods for gastric residence systems
WO2025042350A1 (en) * 2023-08-24 2025-02-27 Junion Therapeutics (Xiamen) Co., Ltd. A gastric residence article for oral administration
WO2025042349A1 (en) * 2023-08-24 2025-02-27 Junion Therapeutics (Xiamen) Co., Ltd. A gastric residence article for oral administration
WO2025148850A1 (zh) * 2024-01-09 2025-07-17 厦门君德医药科技有限公司 一种胃滞留装置
WO2025153071A1 (en) * 2024-01-18 2025-07-24 Junion Therapeutics (Xiamen) Co., Ltd. Gastric residence article for oral administration
CN120154807B (zh) * 2024-03-22 2025-11-21 厦门君德医药科技有限公司 一种胃滞留装置

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9925962D0 (en) * 1999-11-02 1999-12-29 Novartis Ag Organic compounds
AU2007207618B2 (en) * 2006-01-18 2011-03-24 Foresee Pharmaceuticals Co., Ltd. Pharmaceutical compositions with enhanced stability
ES2368356T3 (es) * 2007-07-06 2011-11-16 Basf Corporation Composición de retención gástrica basada en un producto de reacción hidrosoluble procedente de un precursor que contiene un grupo vinilo.
EP2555756B1 (en) * 2010-04-07 2018-08-22 Lupin Limited Controlled release pharmaceutical compositions of tapentadol
EP3482776B1 (en) * 2010-08-06 2020-07-15 Endoshape, Inc. Radiopaque shape memory polymers for medical devices
RU2766335C2 (ru) * 2014-06-11 2022-03-15 Массачусетс Инститьют Оф Текнолоджи Удерживаемые структуры и связанные способы
CN108472249A (zh) * 2015-10-23 2018-08-31 林德拉有限公司 用于治疗剂缓释的胃驻留系统及其使用方法
EP3386488B1 (en) * 2015-12-08 2023-09-06 Lyndra Therapeutics, Inc. Geometric configurations for gastric residence systems
CN109310639A (zh) * 2016-05-27 2019-02-05 林德拉有限公司 用于胃驻留系统的材料结构
JP2019532947A (ja) * 2016-09-30 2019-11-14 リンドラ,インコーポレイティド アダマンタン系薬物の持続的送達のための胃内滞留システム
EP3634382A4 (en) * 2017-06-09 2021-07-07 Lyndra Therapeutics, Inc. STOMACHING SYSTEMS WITH RELEASE RATE MODULATING FILMS
WO2019060458A1 (en) * 2017-09-20 2019-03-28 Lyndra, Inc. ENCAPSULATION OF GASTRIC SYSTEMS
CN113939286A (zh) * 2019-03-25 2022-01-14 道格拉斯制药有限公司 缓释药物制剂

Also Published As

Publication number Publication date
CN115003335A (zh) 2022-09-02
JP2022553862A (ja) 2022-12-26
AU2020378438A1 (en) 2022-06-02
WO2021092491A1 (en) 2021-05-14
MX2022005494A (es) 2022-08-11
EP4054545A1 (en) 2022-09-14
BR112022008908A2 (pt) 2022-10-11
US20220387311A1 (en) 2022-12-08
CA3160665A1 (en) 2021-05-14
EP4054545A4 (en) 2024-02-14

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