JP2022553839A5 - - Google Patents

Info

Publication number
JP2022553839A5
JP2022553839A5 JP2022525948A JP2022525948A JP2022553839A5 JP 2022553839 A5 JP2022553839 A5 JP 2022553839A5 JP 2022525948 A JP2022525948 A JP 2022525948A JP 2022525948 A JP2022525948 A JP 2022525948A JP 2022553839 A5 JP2022553839 A5 JP 2022553839A5
Authority
JP
Japan
Prior art keywords
here
antibody
amino acid
seq
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022525948A
Other languages
English (en)
Japanese (ja)
Other versions
JP7716399B2 (ja
JP2022553839A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/058373 external-priority patent/WO2021087368A2/en
Publication of JP2022553839A publication Critical patent/JP2022553839A/ja
Publication of JP2022553839A5 publication Critical patent/JP2022553839A5/ja
Application granted granted Critical
Publication of JP7716399B2 publication Critical patent/JP7716399B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022525948A 2019-11-01 2020-10-30 抗-cd45抗体及びそのコンジュゲート Active JP7716399B2 (ja)

Applications Claiming Priority (27)

Application Number Priority Date Filing Date Title
US201962929601P 2019-11-01 2019-11-01
US201962929194P 2019-11-01 2019-11-01
US201962929137P 2019-11-01 2019-11-01
US201962929288P 2019-11-01 2019-11-01
US201962929283P 2019-11-01 2019-11-01
US201962929347P 2019-11-01 2019-11-01
US201962929207P 2019-11-01 2019-11-01
US62/929,207 2019-11-01
US62/929,288 2019-11-01
US62/929,601 2019-11-01
US62/929,347 2019-11-01
US62/929,194 2019-11-01
US62/929,137 2019-11-01
US62/929,283 2019-11-01
US201962940742P 2019-11-26 2019-11-26
US62/940,742 2019-11-26
US202062978147P 2020-02-18 2020-02-18
US62/978,147 2020-02-18
US202063015348P 2020-04-24 2020-04-24
US63/015,348 2020-04-24
US202063046164P 2020-06-30 2020-06-30
US202063046046P 2020-06-30 2020-06-30
US63/046,164 2020-06-30
US63/046,046 2020-06-30
US202063084903P 2020-09-29 2020-09-29
US63/084,903 2020-09-29
PCT/US2020/058373 WO2021087368A2 (en) 2019-11-01 2020-10-30 Anti-cd45 antibodies and conjugates thereof

Publications (3)

Publication Number Publication Date
JP2022553839A JP2022553839A (ja) 2022-12-26
JP2022553839A5 true JP2022553839A5 (https=) 2023-11-14
JP7716399B2 JP7716399B2 (ja) 2025-07-31

Family

ID=75715351

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022525948A Active JP7716399B2 (ja) 2019-11-01 2020-10-30 抗-cd45抗体及びそのコンジュゲート

Country Status (12)

Country Link
US (2) US12570756B2 (https=)
EP (1) EP4051711A4 (https=)
JP (1) JP7716399B2 (https=)
KR (1) KR20220091567A (https=)
CN (2) CN121574249A (https=)
AU (1) AU2020376934A1 (https=)
BR (1) BR112022008371A2 (https=)
CA (1) CA3156740A1 (https=)
IL (1) IL292628A (https=)
MX (1) MX2022005249A (https=)
TW (1) TWI904109B (https=)
WO (1) WO2021087368A2 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3877416A4 (en) 2018-10-30 2022-07-27 Magenta Therapeutics, Inc. ANTI-CD45 ANTIBODIES AND CONJUGATES THEREOF
WO2020092655A1 (en) * 2018-10-30 2020-05-07 Magenta Therapeutics, Inc. Methods for allogeneic hematopoietic stem cell transplantation
IL292628A (en) 2019-11-01 2022-07-01 Magenta Therapeutics Inc Anti-cd45 antibody and conjugates accordingly
US20250326856A1 (en) * 2022-05-31 2025-10-23 Fred Hutchison Cancer Center Humanized anti-cd45 antibodies and uses thereof
WO2024064771A1 (en) * 2022-09-20 2024-03-28 Vor Biopharma Inc. Anti-cd45-ign antibody drug conjugates and uses thereof
IL321599A (en) * 2022-12-23 2025-08-01 Cimeio Therapeutics Ag Antibodies targeting cd45
WO2025064944A1 (en) * 2023-09-20 2025-03-27 Vor Biopharma Inc. Anti-cd45 antibody-drug conjugate pharmaceutical compositions
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof
CN120554516B (zh) * 2025-07-30 2025-10-24 杭州华大生命科学研究院 抗cd45抗体及其应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7112661B1 (en) * 1998-10-30 2006-09-26 The Research Foundation Of State University Of New York Variable heavy chain and variable light chain regions of antibodies to human platelet glycoprotein Ib alpha
CN101356189A (zh) * 2005-11-10 2009-01-28 受体生物公司 肝细胞生长因子内含子融合蛋白
AR056857A1 (es) * 2005-12-30 2007-10-24 U3 Pharma Ag Anticuerpos dirigidos hacia her-3 (receptor del factor de crecimiento epidérmico humano-3) y sus usos
AU2007284651B2 (en) 2006-08-09 2014-03-20 Institute For Systems Biology Organ-specific proteins and methods of their use
WO2008085878A2 (en) * 2007-01-03 2008-07-17 Morphotek, Inc. High affinity antibodies that neutralize staphylcoccus enterotoxin b
JP2010532158A (ja) * 2007-04-02 2010-10-07 アムジェン フレモント インク. 抗IgE抗体
US9243057B2 (en) * 2010-08-31 2016-01-26 The Regents Of The University Of California Antibodies for botulinum neurotoxins
KR102276528B1 (ko) * 2011-09-30 2021-07-12 추가이 세이야쿠 가부시키가이샤 이온 농도 의존성 결합 분자 라이브러리
CN104178454B (zh) * 2013-05-24 2019-03-08 益善生物技术股份有限公司 一种循环肿瘤细胞的富集、分析方法
ES3007999T3 (en) * 2015-04-21 2025-03-21 Genentech Inc Compositions and methods for prostate cancer analysis
GB201601073D0 (en) * 2016-01-20 2016-03-02 Ucb Biopharma Sprl Antibodies
US20170189548A1 (en) 2015-11-25 2017-07-06 Immunogen, Inc. Pharmaceutical formulations and methods of use thereof
WO2017155937A1 (en) * 2016-03-07 2017-09-14 Actinium Pharmaceuticals, Inc. Stabilized radiolabeled anti-cd45 immunoglobulin compositions
CN109641051A (zh) * 2016-06-17 2019-04-16 美真达治疗公司 用于耗尽细胞的组合物和方法
JP2020530280A (ja) * 2017-07-03 2020-10-22 トルク セラピューティクス, インコーポレイテッド 免疫刺激性融合分子およびその使用
CN109991410B (zh) * 2017-12-29 2022-07-05 上海白泽医学检验所有限公司 一种含抗cd45单抗的组合物及其使用方法
AU2019366960A1 (en) 2018-10-23 2021-05-27 Regeneron Pharmaceuticals, Inc. Fc silenced antibody drug conjugates (ADCs) and uses thereof
US20200376135A1 (en) 2018-10-23 2020-12-03 Magenta Therapeutics, Inc. Fc silenced antibody drug conjugates (adcs) and uses thereof
EP3877416A4 (en) * 2018-10-30 2022-07-27 Magenta Therapeutics, Inc. ANTI-CD45 ANTIBODIES AND CONJUGATES THEREOF
IL292628A (en) 2019-11-01 2022-07-01 Magenta Therapeutics Inc Anti-cd45 antibody and conjugates accordingly
WO2021168128A1 (en) * 2020-02-18 2021-08-26 Magenta Therapeutics, Inc. Compositions and methods for allogeneic transplantation

Similar Documents

Publication Publication Date Title
JP2022553839A5 (https=)
JP2025160215A5 (https=)
JP2022512629A5 (https=)
JP7650819B2 (ja) 抗-cd45抗体薬物コンジュゲート及びその使用
JP7791923B2 (ja) Cd5+細胞の枯渇のための組成物および方法
JP2022530089A5 (https=)
CN106414465B (zh) 带电荷链接体及其在共轭反应上的应用
AU2021225125B9 (en) Antibody drug conjugate loaded with binary toxins and its application
CN105849086B (zh) 亲水性链接体及其在药物分子和细胞结合分子共轭反应上的应用
JP2020504112A5 (https=)
JP2022163075A (ja) 細胞の枯渇のための組成物および方法
US10576161B2 (en) Compositions and methods for the depletion of CD137+ cells
JP5314590B2 (ja) カンプトテシン結合部分
JP2019522050A5 (https=)
RU2014116878A (ru) Цитотоксические пептиды и их конъюгаты антитело-лекарственное средство
JP2016505019A5 (https=)
JP2015534579A5 (https=)
CN107683146A (zh) 位点特异性抗体‑药物缀合物
JP2025183307A5 (https=)
US20220175944A1 (en) Anti-cd117 antibody-drug conjugates and uses thereof
CN108601952B (zh) 雷公藤内酯的葡萄糖缀合物、类似物及其用途
JP2022530438A5 (https=)
US20220177577A1 (en) Anti-cd117 antibody drug conjugates and uses thereof
WO2019108860A4 (en) Compositions and methods for the depletion of cd2+ cells
JP2022531141A5 (https=)