JP2022553351A5 - - Google Patents
Info
- Publication number
- JP2022553351A5 JP2022553351A5 JP2022523718A JP2022523718A JP2022553351A5 JP 2022553351 A5 JP2022553351 A5 JP 2022553351A5 JP 2022523718 A JP2022523718 A JP 2022523718A JP 2022523718 A JP2022523718 A JP 2022523718A JP 2022553351 A5 JP2022553351 A5 JP 2022553351A5
- Authority
- JP
- Japan
- Prior art keywords
- amino
- carboxamide
- chlorophenyl
- alkyl
- hydroxyethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962926869P | 2019-10-28 | 2019-10-28 | |
| US62/926,869 | 2019-10-28 | ||
| PCT/US2020/056936 WO2021086726A1 (en) | 2019-10-28 | 2020-10-22 | Improved methods, kits, compositions and dosing regimens for the use of heterocyclic inhibitors of erk1 and erk2 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022553351A JP2022553351A (ja) | 2022-12-22 |
| JP2022553351A5 true JP2022553351A5 (enExample) | 2023-10-27 |
| JP7738550B2 JP7738550B2 (ja) | 2025-09-12 |
Family
ID=73476229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022523718A Active JP7738550B2 (ja) | 2019-10-28 | 2020-10-22 | Ｅｒｋ１およびｅｒｋ２の複素環式阻害剤の使用のための改善された方法、キット、組成物、ならびに投与レジメン |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230027072A1 (enExample) |
| EP (1) | EP4051264A1 (enExample) |
| JP (1) | JP7738550B2 (enExample) |
| KR (1) | KR20220106754A (enExample) |
| CN (2) | CN120204227A (enExample) |
| AU (1) | AU2020375720A1 (enExample) |
| CA (1) | CA3158910A1 (enExample) |
| TW (1) | TW202128665A (enExample) |
| WO (1) | WO2021086726A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107922387B (zh) | 2015-06-15 | 2024-11-22 | 阿沙纳生物科学公司 | Erk1与erk2的杂环抑制剂及其在癌症治疗中的应用 |
| US11866421B2 (en) * | 2021-05-31 | 2024-01-09 | Epigen Biosciences, Inc. | Pyrimidine and pyridine amine compounds and usage thereof in disease treatment |
| WO2022271919A1 (en) * | 2021-06-24 | 2022-12-29 | Erasca, Inc. | Erk1/2 or shp2 inhibitors and flt3 inhibitors combination therapy |
| KR20240055721A (ko) * | 2021-06-24 | 2024-04-29 | 아사나 바이오사이언시스 엘엘씨 | Erk1/2 억제제 조합 요법 |
| EP4358964A1 (en) * | 2021-06-24 | 2024-05-01 | Erasca, Inc. | Erk1/2 and kras g12c inhibitors combination therapy |
| TW202317123A (zh) * | 2021-06-24 | 2023-05-01 | 美商艾瑞斯卡公司 | Erk1/2及cdk4/6抑制劑之組合療法 |
| US20240299388A1 (en) * | 2021-06-24 | 2024-09-12 | Erasca, Inc. | Erk1/2 and shp2 inhibitors combination therapy |
| KR20240044419A (ko) * | 2021-06-24 | 2024-04-04 | 에라스카, 아이엔씨. | Erk1/2 및 egfr 억제제 조합 요법 |
| CN117940132A (zh) * | 2021-06-24 | 2024-04-26 | 医睿世康药业研发公司 | Erk1/2和kras g12c抑制剂组合疗法 |
| WO2023044065A1 (en) * | 2021-09-17 | 2023-03-23 | Erasca, Inc. | Jak inhibitor with erk1/2 and/or shp2 inhibitors combination therapy |
| WO2024064690A1 (en) * | 2022-09-20 | 2024-03-28 | Erasca, Inc. | Erk1/2 inhibitor polymorph forms |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6743941B2 (en) | 2001-06-15 | 2004-06-01 | Aventis Pharma Deutschland Gmbh | Process for the production of piperidine derivatives |
| CA2547080A1 (en) | 2003-12-02 | 2005-07-28 | Vertex Pharmaceuticals, Inc. | Heterocyclic protein kinase inhibitors and uses thereof |
| US8546404B2 (en) | 2005-12-13 | 2013-10-01 | Merck Sharp & Dohme | Compounds that are ERK inhibitors |
| CA2780892C (en) | 2009-11-13 | 2017-02-14 | Genosco | Kinase inhibitors |
| CN107922387B (zh) | 2015-06-15 | 2024-11-22 | 阿沙纳生物科学公司 | Erk1与erk2的杂环抑制剂及其在癌症治疗中的应用 |
-
2020
- 2020-10-22 US US17/771,945 patent/US20230027072A1/en not_active Abandoned
- 2020-10-22 CN CN202510314107.1A patent/CN120204227A/zh active Pending
- 2020-10-22 KR KR1020227017170A patent/KR20220106754A/ko not_active Ceased
- 2020-10-22 CA CA3158910A patent/CA3158910A1/en active Pending
- 2020-10-22 JP JP2022523718A patent/JP7738550B2/ja active Active
- 2020-10-22 TW TW109136668A patent/TW202128665A/zh unknown
- 2020-10-22 EP EP20808556.3A patent/EP4051264A1/en not_active Withdrawn
- 2020-10-22 CN CN202080091003.4A patent/CN114901274A/zh active Pending
- 2020-10-22 AU AU2020375720A patent/AU2020375720A1/en active Pending
- 2020-10-22 WO PCT/US2020/056936 patent/WO2021086726A1/en not_active Ceased
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