JP2022552199A5 - - Google Patents
Info
- Publication number
- JP2022552199A5 JP2022552199A5 JP2022520968A JP2022520968A JP2022552199A5 JP 2022552199 A5 JP2022552199 A5 JP 2022552199A5 JP 2022520968 A JP2022520968 A JP 2022520968A JP 2022520968 A JP2022520968 A JP 2022520968A JP 2022552199 A5 JP2022552199 A5 JP 2022552199A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- use according
- pemphigus
- human patient
- ennitrile
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025120944A JP2025157438A (ja) | 2019-10-09 | 2025-07-18 | （ｒ）－２－［３－［４－アミノ－３－（２－フルオロ－４－フェノキシ－フェニル）ピラゾロ［３，４－ｄ］ピリミジン－１－イル］ピペリジン－１－カルボニル］－４－メチル－４－［４－（オキセタン－３－イル）ピペラジン－１－イル］ペンタ－２－エンニトリルを投与することによる天疱瘡を処置する方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962913029P | 2019-10-09 | 2019-10-09 | |
| US62/913,029 | 2019-10-09 | ||
| US201962942877P | 2019-12-03 | 2019-12-03 | |
| US62/942,877 | 2019-12-03 | ||
| PCT/US2020/054809 WO2021072095A1 (en) | 2019-10-09 | 2020-10-08 | Methods of treating pemphigus by administering (r)-2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025120944A Division JP2025157438A (ja) | 2019-10-09 | 2025-07-18 | （ｒ）－２－［３－［４－アミノ－３－（２－フルオロ－４－フェノキシ－フェニル）ピラゾロ［３，４－ｄ］ピリミジン－１－イル］ピペリジン－１－カルボニル］－４－メチル－４－［４－（オキセタン－３－イル）ピペラジン－１－イル］ペンタ－２－エンニトリルを投与することによる天疱瘡を処置する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022552199A JP2022552199A (ja) | 2022-12-15 |
| JP2022552199A5 true JP2022552199A5 (https=) | 2023-10-17 |
| JP7784995B2 JP7784995B2 (ja) | 2025-12-12 |
Family
ID=73030241
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022520968A Active JP7784995B2 (ja) | 2019-10-09 | 2020-10-08 | （ｒ）－２－［３－［４－アミノ－３－（２－フルオロ－４－フェノキシ－フェニル）ピラゾロ［３，４－ｄ］ピリミジン－１－イル］ピペリジン－１－カルボニル］－４－メチル－４－［４－（オキセタン－３－イル）ピペラジン－１－イル］ペンタ－２－エンニトリルを投与することによる天疱瘡を処置する方法 |
| JP2025120944A Pending JP2025157438A (ja) | 2019-10-09 | 2025-07-18 | （ｒ）－２－［３－［４－アミノ－３－（２－フルオロ－４－フェノキシ－フェニル）ピラゾロ［３，４－ｄ］ピリミジン－１－イル］ピペリジン－１－カルボニル］－４－メチル－４－［４－（オキセタン－３－イル）ピペラジン－１－イル］ペンタ－２－エンニトリルを投与することによる天疱瘡を処置する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025120944A Pending JP2025157438A (ja) | 2019-10-09 | 2025-07-18 | （ｒ）－２－［３－［４－アミノ－３－（２－フルオロ－４－フェノキシ－フェニル）ピラゾロ［３，４－ｄ］ピリミジン－１－イル］ピペリジン－１－カルボニル］－４－メチル－４－［４－（オキセタン－３－イル）ピペラジン－１－イル］ペンタ－２－エンニトリルを投与することによる天疱瘡を処置する方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20210106583A1 (https=) |
| EP (1) | EP4041240A1 (https=) |
| JP (2) | JP7784995B2 (https=) |
| KR (1) | KR20220079909A (https=) |
| CN (1) | CN115190798A (https=) |
| AU (1) | AU2020363873A1 (https=) |
| BR (1) | BR112022005575A2 (https=) |
| CA (1) | CA3153750A1 (https=) |
| CO (1) | CO2022005949A2 (https=) |
| IL (1) | IL291726A (https=) |
| MX (1) | MX2022004283A (https=) |
| WO (1) | WO2021072095A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025090703A1 (en) * | 2023-10-25 | 2025-05-01 | Principia Biopharma Inc. | Treatment of chronic spontaneous urticaria by administering (r)-2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4- d]pyrimidin-l-yl]piperidine-l-carbonyl]-4-methyl-4-[4-(oxetan-3- yl)piperazin-l-yl]pent-2-enenitrile |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2892900T1 (en) | 2012-09-10 | 2018-01-31 | Principia Biopharma Inc. | Pyrazolopyrimidine compounds as kinase inhibitors |
| CN112353806A (zh) | 2014-02-21 | 2021-02-12 | 普林斯匹亚生物制药公司 | Btk抑制剂的盐和固体形式 |
| SG11201704808VA (en) | 2014-12-18 | 2017-07-28 | Principia Biopharma Inc | Treatment of pemphigus |
| PT3236953T (pt) | 2014-12-24 | 2021-01-29 | Principia Biopharma Inc | Dosagem específica de sítio de um inibidor de btk |
| CN115054586B (zh) * | 2016-06-29 | 2024-08-02 | 普林斯匹亚生物制药公司 | 改性的释放制剂 |
| WO2019208805A1 (ja) * | 2018-04-27 | 2019-10-31 | 小野薬品工業株式会社 | Ｂｔｋ阻害活性を有する化合物を有効成分として含む自己免疫疾患の予防および／または治療剤 |
-
2020
- 2020-10-08 KR KR1020227015113A patent/KR20220079909A/ko active Pending
- 2020-10-08 JP JP2022520968A patent/JP7784995B2/ja active Active
- 2020-10-08 CA CA3153750A patent/CA3153750A1/en active Pending
- 2020-10-08 BR BR112022005575A patent/BR112022005575A2/pt unknown
- 2020-10-08 US US17/066,300 patent/US20210106583A1/en not_active Abandoned
- 2020-10-08 CN CN202080083113.6A patent/CN115190798A/zh active Pending
- 2020-10-08 EP EP20797943.6A patent/EP4041240A1/en active Pending
- 2020-10-08 AU AU2020363873A patent/AU2020363873A1/en active Pending
- 2020-10-08 WO PCT/US2020/054809 patent/WO2021072095A1/en not_active Ceased
- 2020-10-08 MX MX2022004283A patent/MX2022004283A/es unknown
-
2022
- 2022-03-27 IL IL291726A patent/IL291726A/en unknown
- 2022-05-06 CO CONC2022/0005949A patent/CO2022005949A2/es unknown
- 2022-09-30 US US17/957,073 patent/US20230158033A1/en active Pending
-
2025
- 2025-07-18 JP JP2025120944A patent/JP2025157438A/ja active Pending
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