JP2022551081A5 - - Google Patents

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Publication number
JP2022551081A5
JP2022551081A5 JP2022520371A JP2022520371A JP2022551081A5 JP 2022551081 A5 JP2022551081 A5 JP 2022551081A5 JP 2022520371 A JP2022520371 A JP 2022520371A JP 2022520371 A JP2022520371 A JP 2022520371A JP 2022551081 A5 JP2022551081 A5 JP 2022551081A5
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JP
Japan
Prior art keywords
seq
amino acid
acid sequence
antigen
variable domain
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JP2022520371A
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English (en)
Japanese (ja)
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JP7387885B2 (ja
JP2022551081A (ja
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Priority claimed from PCT/EP2020/077586 external-priority patent/WO2021064137A2/en
Publication of JP2022551081A publication Critical patent/JP2022551081A/ja
Publication of JP2022551081A5 publication Critical patent/JP2022551081A5/ja
Priority to JP2023194494A priority Critical patent/JP7809680B2/ja
Application granted granted Critical
Publication of JP7387885B2 publication Critical patent/JP7387885B2/ja
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JP2022520371A 2019-10-02 2020-10-01 癌処置のための多重特異性結合タンパク質 Active JP7387885B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023194494A JP7809680B2 (ja) 2019-10-02 2023-11-15 癌処置のための多重特異性結合タンパク質

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19201200.3 2019-10-02
EP19201200 2019-10-02
PCT/EP2020/077586 WO2021064137A2 (en) 2019-10-02 2020-10-01 Multi-specific binding proteins for cancer treatment

Related Child Applications (1)

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JP2023194494A Division JP7809680B2 (ja) 2019-10-02 2023-11-15 癌処置のための多重特異性結合タンパク質

Publications (3)

Publication Number Publication Date
JP2022551081A JP2022551081A (ja) 2022-12-07
JP2022551081A5 true JP2022551081A5 (enExample) 2022-12-27
JP7387885B2 JP7387885B2 (ja) 2023-11-28

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ID=68136317

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JP2022520371A Active JP7387885B2 (ja) 2019-10-02 2020-10-01 癌処置のための多重特異性結合タンパク質
JP2023194494A Active JP7809680B2 (ja) 2019-10-02 2023-11-15 癌処置のための多重特異性結合タンパク質

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Country Status (24)

Country Link
US (2) US11732045B2 (enExample)
EP (1) EP4038100A2 (enExample)
JP (2) JP7387885B2 (enExample)
KR (1) KR20220075383A (enExample)
CN (4) CN122103354A (enExample)
AR (1) AR120138A1 (enExample)
AU (1) AU2020358893A1 (enExample)
BR (1) BR112022004047A2 (enExample)
CA (1) CA3153372A1 (enExample)
CL (1) CL2022000664A1 (enExample)
CO (1) CO2022003552A2 (enExample)
CR (1) CR20220136A (enExample)
DO (1) DOP2022000060A (enExample)
EC (1) ECSP22019193A (enExample)
IL (1) IL291817A (enExample)
JO (1) JOP20220079A1 (enExample)
MX (1) MX2022004042A (enExample)
MY (1) MY209387A (enExample)
PE (1) PE20221412A1 (enExample)
PH (1) PH12022550693A1 (enExample)
SA (1) SA522432139B1 (enExample)
TW (1) TWI878355B (enExample)
UA (1) UA130106C2 (enExample)
WO (1) WO2021064137A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023504675A (ja) 2020-05-19 2023-02-06 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ガンの処置のための結合分子
CN117321087A (zh) 2021-03-26 2023-12-29 先天制药公司 包含与细胞因子融合用于nk细胞衔接的nkp46结合位点、癌抗原结合位点的多特异性蛋白质
US12065427B2 (en) 2021-04-29 2024-08-20 Boehringer Ingelheim International Gmbh Heterocyclic compounds capable of activating STING
WO2022258678A1 (en) 2021-06-09 2022-12-15 Innate Pharma Multispecific proteins binding to nkp30, a cytokine receptor, a tumour antigen and cd16a
CN117616050A (zh) 2021-06-09 2024-02-27 先天制药公司 与nkp46、细胞因子受体、肿瘤抗原和cd16a结合的多特异性蛋白质
WO2022258691A1 (en) 2021-06-09 2022-12-15 Innate Pharma Multispecific proteins binding to nkg2d, a cytokine receptor, a tumour antigen and cd16a
CN114395045B (zh) * 2021-12-07 2023-06-09 合肥天港免疫药物有限公司 B7h6抗体及其应用
CN114395047B (zh) * 2021-12-07 2023-11-07 合肥天港免疫药物有限公司 双特异性抗体及其应用
CN114395043B (zh) * 2021-12-07 2023-07-11 合肥天港免疫药物有限公司 Ncr3lg1抗体及其应用
US20240174642A1 (en) 2022-10-26 2024-05-30 Boehringer Ingelheim International Gmbh Heterocyclic compounds capable of activating sting
WO2024088991A1 (en) 2022-10-26 2024-05-02 Boehringer Ingelheim International Gmbh Heterocyclic compounds capable of activating sting
AU2023370123A1 (en) 2022-10-26 2025-04-17 Boehringer Ingelheim International Gmbh Heterocyclic compounds capable of activating sting
WO2024208818A1 (en) 2023-04-04 2024-10-10 Innate Pharma Modular chimeric antigen receptor

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5731A (en) 1848-08-22 Elisha k
US168A (en) 1837-04-17 Improvement in fire-arms
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
EP0281604B1 (en) 1986-09-02 1993-03-31 Enzon Labs Inc. Single polypeptide chain binding molecules
FI903489A7 (fi) 1988-11-11 1990-07-10 Medical Res Council Yhden osan sisältävät ligandit, näitä ligandeja sisältävät reseptorit, menetelmiä niiden valmistamiseksi sekä ligandien ja reseptorien käytt ö
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
WO1993008829A1 (en) 1991-11-04 1993-05-13 The Regents Of The University Of California Compositions that mediate killing of hiv-infected cells
WO1994003678A1 (en) 1992-08-10 1994-02-17 Alcan Aluminium Uk Limited Fence
DE69334275D1 (de) 1992-08-21 2009-05-20 Univ Bruxelles Immunoglobuline ohne Leichtkette
ATE199392T1 (de) 1992-12-04 2001-03-15 Medical Res Council Multivalente und multispezifische bindungsproteine, deren herstellung und verwendung
CA2163032C (en) 1993-06-03 2001-02-06 John Landon Antibody fragments in therapy
EP0739981A1 (en) 1995-04-25 1996-10-30 Vrije Universiteit Brussel Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes
EP1361892A4 (en) 2001-01-17 2004-10-13 Trubion Pharmaceuticals Inc BINDING DOMAIN FUSION PROTEIN Immunoglobulin
EP1456410A2 (en) 2001-12-11 2004-09-15 AlgoNomics N.V. Method for displaying loops from immunoglobulin domains in different contexts
NL1019562C2 (nl) 2001-12-13 2003-06-17 Heineken Tech Services Klepsamenstel voor gebruik bij drankafgifte.
US8764654B2 (en) 2008-03-19 2014-07-01 Zin Technologies, Inc. Data acquisition for modular biometric monitoring system
US8236308B2 (en) * 2005-10-11 2012-08-07 Micromet Ag Composition comprising cross-species-specific antibodies and uses thereof
CN101287764B (zh) 2005-10-12 2013-11-13 莫佛塞斯公司 特异性针对人CD38的完全人HuCAL GOLD-衍生治疗抗体的生成和鉴定
US7858759B2 (en) 2007-10-04 2010-12-28 Zymogenetics, Inc. Anti-zB7H6 antibody-drug conjugates
EP3663318A1 (en) 2008-01-07 2020-06-10 Amgen Inc. Method for making antibody fc-heterodimeric molecules using electrostatic steering effects
FI20090280L (fi) 2009-07-17 2011-01-18 Kone Corp Hissijärjestely ja menetelmä hissikorin liikuttamiseksi hissikuilussa
CA2777527C (en) 2009-12-23 2020-06-23 Esbatech, An Alcon Biomedical Research Unit Llc Method for decreasing immunogenicity
WO2012162067A2 (en) 2011-05-21 2012-11-29 Macrogenics, Inc. Cd3-binding molecules capable of binding to human and non-human cd3
CA3141978A1 (en) 2011-06-23 2012-12-27 Ablynx Nv Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains
MY167125A (en) 2011-08-17 2018-08-13 Glaxo Group Ltd Modified proteins and peptides
DK2766392T3 (da) * 2011-10-10 2019-10-07 Xencor Inc Fremgangsmåde til oprensning af antistoffer
CN104395344B (zh) * 2012-05-07 2019-08-13 达特茅斯大学理事会 抗b7-h6抗体、融合蛋白及其使用方法
CN104640561A (zh) * 2012-07-23 2015-05-20 酵活有限公司 包含轻链和重链的选择性配对的免疫球蛋白构建体
US11291721B2 (en) * 2016-03-21 2022-04-05 Marengo Therapeutics, Inc. Multispecific and multifunctional molecules and uses thereof
CN114634569B (zh) * 2016-04-15 2024-08-20 达特茅斯大学理事会 高亲和力b7-h6抗体和抗体片段
EP3848393A1 (en) 2016-05-18 2021-07-14 Boehringer Ingelheim International GmbH Antibody molecules for cancer treatment
TWI848953B (zh) * 2018-06-09 2024-07-21 德商百靈佳殷格翰國際股份有限公司 針對癌症治療之多特異性結合蛋白

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