JP2024544757A5 - - Google Patents

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Publication number
JP2024544757A5
JP2024544757A5 JP2024529287A JP2024529287A JP2024544757A5 JP 2024544757 A5 JP2024544757 A5 JP 2024544757A5 JP 2024529287 A JP2024529287 A JP 2024529287A JP 2024529287 A JP2024529287 A JP 2024529287A JP 2024544757 A5 JP2024544757 A5 JP 2024544757A5
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JP
Japan
Prior art keywords
domain
linker
immunoglobulin
dba
hinge
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024529287A
Other languages
English (en)
Japanese (ja)
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JP2024544757A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/080043 external-priority patent/WO2023092006A1/en
Publication of JP2024544757A publication Critical patent/JP2024544757A/ja
Publication of JP2024544757A5 publication Critical patent/JP2024544757A5/ja
Pending legal-status Critical Current

Links

JP2024529287A 2021-11-17 2022-11-17 タンパク質複合体の組成物およびその使用方法 Pending JP2024544757A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163280494P 2021-11-17 2021-11-17
US63/280,494 2021-11-17
PCT/US2022/080043 WO2023092006A1 (en) 2021-11-17 2022-11-17 Compositions of protein complexes and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2024544757A JP2024544757A (ja) 2024-12-04
JP2024544757A5 true JP2024544757A5 (enExample) 2025-11-26

Family

ID=84981857

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024529287A Pending JP2024544757A (ja) 2021-11-17 2022-11-17 タンパク質複合体の組成物およびその使用方法

Country Status (11)

Country Link
US (1) US20240366776A1 (enExample)
EP (1) EP4433097A1 (enExample)
JP (1) JP2024544757A (enExample)
KR (1) KR20240101593A9 (enExample)
CN (1) CN118555973A (enExample)
AU (1) AU2022390563A1 (enExample)
CA (1) CA3238260A1 (enExample)
IL (1) IL312802A (enExample)
MX (1) MX2024005948A (enExample)
TW (1) TW202330628A (enExample)
WO (1) WO2023092006A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2026517390A (ja) * 2023-05-16 2026-05-29 エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト Pd-1調節il-2免疫サイトカインおよびその使用
WO2026104330A1 (en) * 2024-11-12 2026-05-21 F. Hoffmann-La Roche Ag Pd-1-regulated il-2 immunoconjugates and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7148539B2 (ja) * 2017-04-03 2022-10-05 エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト 免疫抱合体
KR102461885B1 (ko) * 2017-04-03 2022-11-03 에프. 호프만-라 로슈 아게 항-pd-1 항체와 돌연변이 il-2 또는 il-15의 면역접합체
AU2018287317B2 (en) * 2017-06-19 2024-06-20 Medicenna Therapeutics Inc. Uses and methods for IL-2 superagonists, agonists, and fusions thereof
US11970537B2 (en) * 2017-12-26 2024-04-30 Nanjing GenScript Biotech Co., Ltd. Fusion protein dimer using antibody Fc region as backbone and use thereof
JP7778571B2 (ja) * 2019-06-05 2025-12-02 アッシャー バイオセラピューティクス, インコーポレイテッド 免疫細胞機能をモジュレートするための変異体インターロイキン-2ポリペプチドと抗原結合分子の融合体
KR20230010251A (ko) * 2020-05-13 2023-01-18 보넘 테라퓨틱스, 인크. 단백질 복합체의 조성물 및 그의 사용 방법

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