JP2022547915A5 - - Google Patents
Info
- Publication number
- JP2022547915A5 JP2022547915A5 JP2022514985A JP2022514985A JP2022547915A5 JP 2022547915 A5 JP2022547915 A5 JP 2022547915A5 JP 2022514985 A JP2022514985 A JP 2022514985A JP 2022514985 A JP2022514985 A JP 2022514985A JP 2022547915 A5 JP2022547915 A5 JP 2022547915A5
- Authority
- JP
- Japan
- Prior art keywords
- unsubstituted
- groups
- substituted
- group
- further substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910843097 | 2019-09-06 | ||
| CN201910843097.5 | 2019-09-06 | ||
| PCT/CN2020/113265 WO2021043217A1 (zh) | 2019-09-06 | 2020-09-03 | 具有Axl与c-Met激酶抑制活性的化合物及其制备和应用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022547915A JP2022547915A (ja) | 2022-11-16 |
| JP2022547915A5 true JP2022547915A5 (https=) | 2023-10-30 |
| JP7542613B2 JP7542613B2 (ja) | 2024-08-30 |
Family
ID=74832853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022514985A Active JP7542613B2 (ja) | 2019-09-06 | 2020-09-03 | Ａｘｌとｃ－Ｍｅｔキナーゼ阻害活性を有する化合物およびその製造と使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US12479850B2 (https=) |
| EP (1) | EP4029862A4 (https=) |
| JP (1) | JP7542613B2 (https=) |
| KR (1) | KR102826937B1 (https=) |
| CN (2) | CN112457295B (https=) |
| AU (1) | AU2020342108B2 (https=) |
| WO (1) | WO2021043217A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022551422A (ja) * | 2019-09-26 | 2022-12-09 | エグゼリクシス， インコーポレイテッド | ピリドン化合物およびタンパク質キナーゼの調節における使用の方法 |
| BR112022019517A2 (pt) | 2020-03-30 | 2022-12-06 | Hutchison Medipharma Ltd | Compostos de amida e usos dos mesmos |
| IT202100022682A1 (it) * | 2021-09-01 | 2023-03-01 | Luigi Frati | Derivati pirimidinici e loro uso nel trattamento di tumori |
| CN114573553B (zh) * | 2022-01-27 | 2023-11-10 | 广州六顺生物科技有限公司 | 杂芳环类衍生物及其制备方法和应用 |
| US12421207B2 (en) * | 2022-02-16 | 2025-09-23 | Cmg Pharmaceutical Co., Ltd. | Pyrimidinedione-based compounds as AXL, c-MET, and Mer inhibitors and methods of use thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201402004YA (en) * | 2011-11-14 | 2014-05-29 | Cephalon Inc | Uracil derivatives as axl and c-met kinase inhibitors |
| TW201422592A (zh) | 2012-08-27 | 2014-06-16 | Boehringer Ingelheim Int | β－分泌酶抑制劑 |
| AU2014370186A1 (en) | 2013-12-26 | 2016-07-14 | Ignyta, Inc. | Pyrazolo[1,5-a]pyridine derivatives and methods of their use |
| KR102483020B1 (ko) | 2016-03-28 | 2023-01-04 | 인사이트 코포레이션 | Tam 저해제로서의 피롤로트리아진 화합물 |
| CN106543145B (zh) * | 2016-10-28 | 2019-07-19 | 山西医科大学 | c-Met激酶抑剂3-(4-氟苯基)嘧啶酮-5-甲酸酰胺衍生物、制备方法与应用 |
| US11623923B2 (en) * | 2017-11-24 | 2023-04-11 | Medshine Discovery, Inc. | Uracil compound as c-MET/AXL inhibitor |
| US20210177828A1 (en) * | 2018-01-17 | 2021-06-17 | Nanjing Transthera Biosciences Co., Ltd. | Tam family kinase /and csf1r kinase inhibitor and use thereof |
| CA3114987A1 (en) | 2018-08-27 | 2020-03-05 | Beijing Yuezhikangtai Biomedicines Co., Ltd. | Multi-substituted pyridone derivatives and medical use thereof |
| UY38349A (es) * | 2018-08-30 | 2020-03-31 | Array Biopharma Inc | Compuestos de pirazolo[3,4-b]piridina como inhibidores de cinasas tam y met |
-
2020
- 2020-09-03 JP JP2022514985A patent/JP7542613B2/ja active Active
- 2020-09-03 WO PCT/CN2020/113265 patent/WO2021043217A1/zh not_active Ceased
- 2020-09-03 EP EP20861098.0A patent/EP4029862A4/en active Pending
- 2020-09-03 KR KR1020227011083A patent/KR102826937B1/ko active Active
- 2020-09-03 AU AU2020342108A patent/AU2020342108B2/en active Active
- 2020-09-03 US US17/640,424 patent/US12479850B2/en active Active
- 2020-09-03 CN CN202010916067.5A patent/CN112457295B/zh active Active
- 2020-09-03 CN CN202211096410.1A patent/CN116283916B/zh active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022547915A5 (https=) | ||
| JP2024105360A5 (https=) | ||
| JP2023052069A5 (https=) | ||
| CA2587528A1 (en) | Method for preparing n-phenylpyrazole-1-carboxamides | |
| JP2018530587A5 (https=) | ||
| RU2009105669A (ru) | Способ получения 3-замещенных 2-амино-5-галогенбензамидов | |
| CA2454306A1 (en) | Substituted dihydro 3-halo-1h-pyrazole-5-carboxylates their preparation and use | |
| AR040350A1 (es) | Inhibidores de caspasa y usos de los mismos | |
| JP2024519815A5 (https=) | ||
| JPH1036206A5 (https=) | ||
| ATE75737T1 (de) | Indenothiazolderivate und verfahren zu ihrer herstellung. | |
| KR850003719A (ko) | 시아노피라졸 제초제에 대한 개량 | |
| PE20220580A1 (es) | Carboxamidas de tiofeno sustituidas y derivados de estas | |
| JP2024000769A5 (https=) | ||
| PT78238A (fr) | Preparation de nouveaux <carbethoxy-2 benzalkylamido-4 phenoxy>-1 amino-3 propanols-2 utiles en therapeutique | |
| ATE273981T1 (de) | Fungiizide 6-(trifluormethyl-phenyl)- triazolpyrimidine | |
| GB1477957A (en) | Heterocyclic substituted styrenes and their use as optical brighteners | |
| NZ335105A (en) | Process for alkylating hindered sulfonamides | |
| DK412581A (da) | Ethenylimidazolderivater og fremgangsmaade til fremstilling heraf | |
| GB1124539A (en) | New substituted-hydrazino benzisothiazoles and process for preparing same | |
| ATE282040T1 (de) | 6-phenyl-pyrazolpyrimidine | |
| KR960007566A (ko) | 신규한 퀴놀릴아민 유도체, 그의 제조방법 및 항부정맥제로서의 용도 | |
| IL164436A0 (en) | Fungicidal triazolopyrimidines, method for hte production thereof, use therof for controlling harmful fungi, and agents containing said fungicidal triazolopyrimidines | |
| JP2022518265A5 (https=) | ||
| RU2008145046A (ru) | Производное 2-алкенил-3-аминотиофена и способ его получения |