JP2022545782A5 - - Google Patents

Info

Publication number
JP2022545782A5
JP2022545782A5 JP2022510801A JP2022510801A JP2022545782A5 JP 2022545782 A5 JP2022545782 A5 JP 2022545782A5 JP 2022510801 A JP2022510801 A JP 2022510801A JP 2022510801 A JP2022510801 A JP 2022510801A JP 2022545782 A5 JP2022545782 A5 JP 2022545782A5
Authority
JP
Japan
Prior art keywords
cells
induction medium
population
mesoderm
differentiation factors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022510801A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022545782A (ja
Filing date
Publication date
Priority claimed from GBGB1911957.7A external-priority patent/GB201911957D0/en
Application filed filed Critical
Publication of JP2022545782A publication Critical patent/JP2022545782A/ja
Publication of JP2022545782A5 publication Critical patent/JP2022545782A5/ja
Pending legal-status Critical Current

Links

JP2022510801A 2019-08-20 2020-08-20 多能性幹細胞から造血性前駆細胞を生産する方法 Pending JP2022545782A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1911957.7A GB201911957D0 (en) 2019-08-20 2019-08-20 Methods of producing haemogenic progenitor cells from pluripotent stem cells
GB1911957.7 2019-08-20
PCT/EP2020/073396 WO2021032851A1 (en) 2019-08-20 2020-08-20 Methods of producing haemogenic progenitor cells from pluripotent stem cells

Publications (2)

Publication Number Publication Date
JP2022545782A JP2022545782A (ja) 2022-10-31
JP2022545782A5 true JP2022545782A5 (https=) 2023-08-18

Family

ID=68099409

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022510801A Pending JP2022545782A (ja) 2019-08-20 2020-08-20 多能性幹細胞から造血性前駆細胞を生産する方法

Country Status (12)

Country Link
US (1) US20220267733A1 (https=)
EP (1) EP4017967A1 (https=)
JP (1) JP2022545782A (https=)
KR (1) KR20220049032A (https=)
CN (1) CN114269906A (https=)
AU (1) AU2020332863A1 (https=)
BR (1) BR112022003089A2 (https=)
CA (1) CA3150427A1 (https=)
GB (1) GB201911957D0 (https=)
IL (1) IL290605A (https=)
MX (1) MX2022001960A (https=)
WO (1) WO2021032851A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11459372B2 (en) 2020-11-30 2022-10-04 Crispr Therapeutics Ag Gene-edited natural killer cells
WO2022144632A1 (en) 2020-12-30 2022-07-07 Crispr Therapeutics Ag Compositions and methods for differentiating stem cells into nk cells
GB202102297D0 (en) * 2021-02-18 2021-04-07 Adaptimmune Ltd Methods of Producing Haemogenic Endothelial Cells from Pluripotent Stem Cells
CN113046318B (zh) * 2021-04-13 2023-04-18 中国科学院深圳先进技术研究院 一种诱导多能干细胞向造血前体细胞分化的培养基以及方法
EP4326852A4 (en) * 2021-04-22 2025-04-23 Artec Biotech, Inc. Method for producing hematopoietic cells from stem cells using vascular organoids
CN113265377B (zh) * 2021-06-11 2023-01-24 中国医学科学院血液病医院(中国医学科学院血液学研究所) 一种动脉内皮促进功能性t细胞再生的方法
WO2023038436A1 (ko) * 2021-09-10 2023-03-16 의료법인 성광의료재단 전분화능 줄기세포 유래 조혈모세포 제조방법 및 상기 제조된 조혈모세포를 이용한 인간화 마우스 모델 제작방법
CN116410927A (zh) * 2021-12-31 2023-07-11 士泽生物医药（苏州）有限公司 干细胞诱导分化为造血祖细胞的方法
CN116376822A (zh) * 2021-12-31 2023-07-04 北京大学 利用人多潜能干细胞体外制备t淋巴细胞
TW202340453A (zh) * 2022-01-28 2023-10-16 中國大陸商杭州啟函生物科技有限公司 用於基於細胞的免疫療法的方法和組合物
GB202205572D0 (en) 2022-04-14 2022-06-01 Adaptimmune Ltd Engineered T cells
GB202208545D0 (en) 2022-06-10 2022-07-27 Adaptimmune Ltd Production of immune cells
CN114958771B (zh) * 2022-06-27 2023-12-05 广东康盾创新产业集团股份公司 一种ipsc-car-nk细胞的制备方法
CN115247151B (zh) * 2022-09-21 2022-12-27 呈诺再生医学科技(北京)有限公司 制备造血内皮细胞的方法及制备造血干细胞或造血干祖细胞的方法
KR20240054468A (ko) * 2022-10-18 2024-04-26 의료법인 성광의료재단 줄기세포에서 대식세포로의 분화 유도용 배지 조성물 및 이를 이용한 분화 방법
AU2022489613A1 (en) * 2022-12-02 2025-07-10 Nuwacell Biotechnologies Co., Ltd. Methods and compositions for differentiation of pluripotent stem cells and derived natural killer cells
CN117264888A (zh) * 2023-10-11 2023-12-22 苏州艾凯利元生物科技有限公司 一种制备造血干细胞和祖细胞的方法
GB202318950D0 (en) 2023-12-12 2024-01-24 Adaptimmune Ltd Production of immune cells

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008151390A1 (en) * 2007-06-15 2008-12-18 Australian Stem Cell Centre Ltd Differentiation of human embryonic stem cells
US8652845B2 (en) * 2010-03-18 2014-02-18 Kyoto University Method for producing mesodermal cells by culturing under adherent conditions and without co-culture with cells from a different species in a serum-free medium
HUE043785T2 (hu) * 2013-03-13 2019-09-30 Wisconsin Alumni Res Found Módszerek és anyagok humán pluripotens õssejtek hematoendothelialis differenciálására meghatározott körülmények között
US10385313B2 (en) * 2013-10-01 2019-08-20 The Usa, As Represented By The Secretary, Department Of Health And Human Services Human IPSC-derived vascular-related and hematopoetic cells for therapies and toxicology/drug screenings
WO2016123100A1 (en) * 2015-01-26 2016-08-04 Fate Therapeutics, Inc. Methods and compositions for inducing hematopoietic cell differentiation
SG11201706706XA (en) * 2015-02-20 2017-09-28 Wisconsin Alumni Res Found Generating arterial endothelial cell populations
KR20250141836A (ko) * 2015-11-04 2025-09-29 페이트 세러퓨틱스, 인코포레이티드 만능 세포의 유전자 조작
SG11201803145RA (en) * 2015-11-04 2018-05-30 Fate Therapeutics Inc Methods and compositions for inducing hematopoietic cell differentiation
US11261430B2 (en) * 2016-05-03 2022-03-01 The Children's Medical Center Corporation Hematopoietic stem and progenitor cells derived from hemogenic endothelial cells
EP3621630A4 (en) * 2017-06-14 2021-03-10 The Children's Medical Center HEMATOPOIETIC STEM AND PRECURSOR CELLS FROM HEMOGENIC ENDOTHELIAL CELLS BY EPISOMAL PLASMID GENERAL TRANSFER
CN112041428B (zh) * 2018-01-18 2024-05-24 新加坡科技研究局 用于在悬浮培养物中分化人多能干细胞系的方法
GB202006903D0 (en) * 2020-05-11 2020-06-24 Adaptimmune Ltd Modified iPSCs

Similar Documents

Publication Publication Date Title
JP2022545782A5 (https=)
JP2022545415A5 (https=)
US12241087B2 (en) Compositions and methods for differentiating stem cells into NK cells
JP7061961B2 (ja) 多能性幹細胞の免疫細胞への分化を誘導する方法
JP6344821B2 (ja) 造血前駆体の集団および造血前駆体のための幹細胞を富化する方法
JP7212615B2 (ja) 多能性幹細胞からｈｌａホモ接合免疫細胞への指向分化方法
US9771561B2 (en) Method of making primate cells expressing apelin receptor that have mesangioblast potential
JP2024507472A5 (https=)
JP2022545078A5 (https=)
CN103003416A (zh) 从小体积的外周血产生诱导性多潜能干细胞
Netsrithong et al. Engineered T cells from induced pluripotent stem cells: from research towards clinical implementation
CN107429230A (zh) 用于诱导造血细胞分化的方法和组合物
CA2905786A1 (en) Methods and materials for hematoendothelial differentiation of human pluripotent stem cells under defined conditions
IL305018A (en) Methods of producing haemogenic endothelial cells from pluripotent stem cells
Galić et al. Generation of T lineage cells from human embryonic stem cells in a feeder free system
JP2022545416A5 (https=)
Liu et al. Progress and challenges in generating functional hematopoietic stem/progenitor cells from human pluripotent stem cells
Lu et al. Enhanced generation of hematopoietic cells from human hepatocarcinoma cell− stimulated human embryonic and induced pluripotent stem cells
Philonenko et al. Recapitulative haematopoietic development of human pluripotent stem cells in the absence of exogenous haematopoietic cytokines
Gong et al. Interplay of transcription factors and microRNAs during embryonic hematopoiesis
Lee et al. Forced expression of HoxB4 enhances hematopoietic differentiation by human embryonic stem cells
CN115087732B (zh) 来自人T细胞来源的iPS细胞的细胞毒性T细胞
Wilkinson et al. Expanded potential stem cell media as a tool to study human developmental hematopoiesis in vitro
Wang Endothelial and hematopoietic cell fate of human embryonic stem cells
WO2023233339A1 (en) Compositions and methods for differentiating stem cells into nk cells