AU2020332863A1 - Methods of producing haemogenic progenitor cells from pluripotent stem cells - Google Patents

Methods of producing haemogenic progenitor cells from pluripotent stem cells Download PDF

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Publication number
AU2020332863A1
AU2020332863A1 AU2020332863A AU2020332863A AU2020332863A1 AU 2020332863 A1 AU2020332863 A1 AU 2020332863A1 AU 2020332863 A AU2020332863 A AU 2020332863A AU 2020332863 A AU2020332863 A AU 2020332863A AU 2020332863 A1 AU2020332863 A1 AU 2020332863A1
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cells
population
mesoderm
progenitor
induction medium
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AU2020332863A
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Lee Carpenter
Cheng Tao Yang
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Adaptimmune Ltd
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Adaptimmune Ltd
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
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    • A61K40/32—T-cell receptors [TCR]
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12N5/10—Cells modified by introduction of foreign genetic material
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/20—Cytokines; Chemokines
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    • C12N2501/20—Cytokines; Chemokines
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2020332863A 2019-08-20 2020-08-20 Methods of producing haemogenic progenitor cells from pluripotent stem cells Abandoned AU2020332863A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1911957.7 2019-08-20
GBGB1911957.7A GB201911957D0 (en) 2019-08-20 2019-08-20 Methods of producing haemogenic progenitor cells from pluripotent stem cells
PCT/EP2020/073396 WO2021032851A1 (en) 2019-08-20 2020-08-20 Methods of producing haemogenic progenitor cells from pluripotent stem cells

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AU2020332863A1 true AU2020332863A1 (en) 2022-03-24

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AU2020332863A Abandoned AU2020332863A1 (en) 2019-08-20 2020-08-20 Methods of producing haemogenic progenitor cells from pluripotent stem cells

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US (1) US20220267733A1 (https=)
EP (1) EP4017967A1 (https=)
JP (1) JP2022545782A (https=)
KR (1) KR20220049032A (https=)
CN (1) CN114269906A (https=)
AU (1) AU2020332863A1 (https=)
BR (1) BR112022003089A2 (https=)
CA (1) CA3150427A1 (https=)
GB (1) GB201911957D0 (https=)
IL (1) IL290605A (https=)
MX (1) MX2022001960A (https=)
WO (1) WO2021032851A1 (https=)

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US11591381B2 (en) 2020-11-30 2023-02-28 Crispr Therapeutics Ag Gene-edited natural killer cells
WO2022144632A1 (en) 2020-12-30 2022-07-07 Crispr Therapeutics Ag Compositions and methods for differentiating stem cells into nk cells
GB202102297D0 (en) * 2021-02-18 2021-04-07 Adaptimmune Ltd Methods of Producing Haemogenic Endothelial Cells from Pluripotent Stem Cells
CN113046318B (zh) * 2021-04-13 2023-04-18 中国科学院深圳先进技术研究院 一种诱导多能干细胞向造血前体细胞分化的培养基以及方法
EP4326852A4 (en) * 2021-04-22 2025-04-23 Artec Biotech, Inc. Method for producing hematopoietic cells from stem cells using vascular organoids
CN113265377B (zh) * 2021-06-11 2023-01-24 中国医学科学院血液病医院(中国医学科学院血液学研究所) 一种动脉内皮促进功能性t细胞再生的方法
JP2024531626A (ja) * 2021-09-10 2024-08-29 スンクワン メディカル ファウンデーション 分化全能性幹細胞由来の造血幹細胞の製造方法、及び製造された造血幹細胞を利用したヒト化マウスモデル作製方法
CN116410927A (zh) * 2021-12-31 2023-07-11 士泽生物医药（苏州）有限公司 干细胞诱导分化为造血祖细胞的方法
CN116376822A (zh) * 2021-12-31 2023-07-04 北京大学 利用人多潜能干细胞体外制备t淋巴细胞
TW202340453A (zh) * 2022-01-28 2023-10-16 中國大陸商杭州啟函生物科技有限公司 用於基於細胞的免疫療法的方法和組合物
GB202205572D0 (en) 2022-04-14 2022-06-01 Adaptimmune Ltd Engineered T cells
GB202208545D0 (en) 2022-06-10 2022-07-27 Adaptimmune Ltd Production of immune cells
CN114958771B (zh) * 2022-06-27 2023-12-05 广东康盾创新产业集团股份公司 一种ipsc-car-nk细胞的制备方法
CN115247151B (zh) * 2022-09-21 2022-12-27 呈诺再生医学科技(北京)有限公司 制备造血内皮细胞的方法及制备造血干细胞或造血干祖细胞的方法
KR20240054468A (ko) * 2022-10-18 2024-04-26 의료법인 성광의료재단 줄기세포에서 대식세포로의 분화 유도용 배지 조성물 및 이를 이용한 분화 방법
US20240316196A1 (en) * 2022-12-02 2024-09-26 Nuwacell Biotechnologies Co., Ltd. Methods and compositions for differentiation of pluripotent stem cells and derived natural killer cells
CN117264888A (zh) * 2023-10-11 2023-12-22 苏州艾凯利元生物科技有限公司 一种制备造血干细胞和祖细胞的方法
GB202318950D0 (en) 2023-12-12 2024-01-24 Adaptimmune Ltd Production of immune cells

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WO2008151390A1 (en) * 2007-06-15 2008-12-18 Australian Stem Cell Centre Ltd Differentiation of human embryonic stem cells
JP5777115B2 (ja) * 2010-03-18 2015-09-09 国立大学法人京都大学 多能性幹細胞から中胚葉細胞への分化誘導法
JP6677631B2 (ja) * 2013-03-13 2020-04-08 ウイスコンシン アラムナイ リサーチ ファウンデーシヨンＷｉｓｃｏｎｓｉｎ Ａｌｕｍｎｉ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ 定義された条件下におけるヒト多能性幹細胞の造血内皮分化のための方法及び材料
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CN114269906A (zh) 2022-04-01
MX2022001960A (es) 2022-03-11
EP4017967A1 (en) 2022-06-29
US20220267733A1 (en) 2022-08-25
GB201911957D0 (en) 2019-10-02
IL290605A (en) 2022-04-01
WO2021032851A1 (en) 2021-02-25
KR20220049032A (ko) 2022-04-20
JP2022545782A (ja) 2022-10-31
CA3150427A1 (en) 2021-02-25
BR112022003089A2 (pt) 2022-05-17

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