|
IL123986A
(en)
*
|
1997-04-24 |
2011-10-31 |
Organon Nv |
Medicinal compounds
|
|
ATE306481T1
(de)
*
|
1999-05-12 |
2005-10-15 |
Ortho Mcneil Pharm Inc |
Pyrazolecarboxamide zur behandlung von fettleibigkeit und anderen erkrankungen
|
|
US7320992B2
(en)
*
|
2003-08-25 |
2008-01-22 |
Amgen Inc. |
Substituted 2,3-dihydro-1h-isoindol-1-one derivatives and methods of use
|
|
NZ592039A
(en)
|
2003-08-27 |
2013-03-28 |
Ophthotech Corp |
Combination therapy for the treatment of ocular neovascular disorders
|
|
GB0518237D0
(en)
*
|
2005-09-07 |
2005-10-19 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
|
US8338437B2
(en)
*
|
2007-02-28 |
2012-12-25 |
Methylgene Inc. |
Amines as small molecule inhibitors
|
|
US8658635B2
(en)
*
|
2008-06-05 |
2014-02-25 |
Glaxosmithkline Intellectual Property Development Limited |
Benzpyrazol derivatives as inhibitors of PI3 kinases
|
|
EP2149552A1
(de)
*
|
2008-07-30 |
2010-02-03 |
Bayer Schering Pharma AG |
5,6 substituierte Benzamid-Derivate als Modulatoren des EP2-Rezeptors
|
|
US9290485B2
(en)
*
|
2010-08-04 |
2016-03-22 |
Novartis Ag |
N-((6-amino-pyridin-3-yl)methyl)-heteroaryl-carboxamides
|
|
RU2013130019A
(ru)
*
|
2010-12-03 |
2015-01-10 |
Аллерган, Инк. |
Новые производные азетидина в качестве модуляторов рецептора сфингозин 1-фосфата (s1p)
|
|
CN103415301A
(zh)
*
|
2011-03-09 |
2013-11-27 |
德国杰特贝林生物制品有限公司 |
用于与包括与人造表面接触的医疗操作一起施用的fxii抑制剂
|
|
US8404859B2
(en)
*
|
2011-03-16 |
2013-03-26 |
Hoffmann-La Roche Inc. |
Thiazole and thiophene compounds
|
|
US20120252853A1
(en)
*
|
2011-04-01 |
2012-10-04 |
H. Lundbeck A/S |
Positive allosteric modulators of nicotinic acetylcholine receptor
|
|
JP2014514302A
(ja)
*
|
2011-04-13 |
2014-06-19 |
メルク・シャープ・アンド・ドーム・コーポレーション |
Bace阻害薬としての5−置換されたイミノチアジン類およびそれのモノおよびジオキシド、組成物およびそれらの使用
|
|
US9340500B2
(en)
*
|
2011-04-20 |
2016-05-17 |
Shionogi & Co., Ltd. |
Aromatic heterocyclic derivative having TRPV4-inhibiting activity
|
|
US9938269B2
(en)
*
|
2011-06-30 |
2018-04-10 |
Abbvie Inc. |
Inhibitor compounds of phosphodiesterase type 10A
|
|
BR112014013136B1
(pt)
*
|
2011-11-30 |
2020-05-26 |
F. Hoffmann-La Roche Ag |
Novos derivados de dihidroisoquinolina-1-ona biciclicos
|
|
AR091022A1
(es)
*
|
2012-05-11 |
2014-12-30 |
Abbvie Inc |
Inhibidores del nampt
|
|
GB201300304D0
(en)
|
2013-01-08 |
2013-02-20 |
Kalvista Pharmaceuticals Ltd |
Benzylamine derivatives
|
|
MY174018A
(en)
|
2013-05-23 |
2020-03-04 |
Kalvista Pharmaceuticals Ltd |
Heterocyclic derivates
|
|
CN106257976B
(zh)
*
|
2014-03-07 |
2021-02-02 |
拜奥克里斯特制药公司 |
人类血浆激肽释放酶抑制剂
|
|
US10772881B2
(en)
*
|
2017-02-27 |
2020-09-15 |
Russell Dahl |
Quinolines that modulate SERCA and their use for treating disease
|
|
GB201421088D0
(en)
|
2014-11-27 |
2015-01-14 |
Kalvista Pharmaceuticals Ltd |
New enzyme inhibitors
|
|
CN104592204B
(zh)
*
|
2014-12-26 |
2017-05-17 |
华润赛科药业有限责任公司 |
达比加群衍生物及其制备方法和用途
|
|
WO2017123518A1
(en)
|
2016-01-11 |
2017-07-20 |
The Rockefeller University |
Aminotriazole immunomodulators for treating autoimmune diseases
|
|
GB201604647D0
(en)
*
|
2016-03-18 |
2016-05-04 |
Mission Therapeutics Ltd |
Novel compounds
|
|
WO2017176958A1
(en)
*
|
2016-04-06 |
2017-10-12 |
The Regents Of The University Of Michigan |
Monofunctional intermediates for ligand-dependent target protein degradation
|
|
AU2017269256B2
(en)
|
2016-05-23 |
2021-02-25 |
The Rockefeller University |
Aminoacylindazole immunomodulators for treatment of autoimmune diseases
|
|
US10858319B2
(en)
*
|
2016-10-03 |
2020-12-08 |
Iomet Pharma Ltd. |
Indole derivatives for use in medicine
|
|
WO2018093695A1
(en)
|
2016-11-18 |
2018-05-24 |
Merck Sharp & Dohme Corp. |
FACTOR XIIa INHIBITORS
|
|
EP3541381B1
(en)
|
2016-11-18 |
2022-12-28 |
Merck Sharp & Dohme LLC |
Inhibitors of factor xiia
|
|
JP2021504490A
(ja)
|
2017-11-29 |
2021-02-15 |
ザ ロックフェラー ユニバーシティーThe Rockefeller University |
自己免疫疾患治療用ピラノピラゾールおよびピラゾロピリジン免疫調節薬
|
|
CN112585119A
(zh)
*
|
2018-08-14 |
2021-03-30 |
Epizyme股份有限公司 |
经取代的吲哚及其使用方法
|
|
WO2021028645A1
(en)
*
|
2019-08-09 |
2021-02-18 |
Kalvista Pharmaceuticals Limited |
Plasma kallikrein inhibitors
|
|
EP4017587A1
(en)
*
|
2019-08-21 |
2022-06-29 |
Kalvista Pharmaceuticals Limited |
Enzyme inhibitors
|