JP2022545159A5 - - Google Patents

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Publication number
JP2022545159A5
JP2022545159A5 JP2022503834A JP2022503834A JP2022545159A5 JP 2022545159 A5 JP2022545159 A5 JP 2022545159A5 JP 2022503834 A JP2022503834 A JP 2022503834A JP 2022503834 A JP2022503834 A JP 2022503834A JP 2022545159 A5 JP2022545159 A5 JP 2022545159A5
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JP
Japan
Application number
JP2022503834A
Other languages
Japanese (ja)
Other versions
JP2022545159A (ja
JPWO2021032938A5 (https=
Filing date
Publication date
Priority claimed from PCT/GB2019/052358 external-priority patent/WO2021032935A1/en
Application filed filed Critical
Publication of JP2022545159A publication Critical patent/JP2022545159A/ja
Publication of JP2022545159A5 publication Critical patent/JP2022545159A5/ja
Publication of JPWO2021032938A5 publication Critical patent/JPWO2021032938A5/ja
Ceased legal-status Critical Current

Links

JP2022503834A 2019-08-21 2020-02-13 酵素阻害剤 Ceased JP2022545159A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/GB2019/052358 WO2021032935A1 (en) 2019-08-21 2019-08-21 Enzyme inhibitors
GBPCT/GB2019/052358 2019-08-21
PCT/GB2020/050334 WO2021032938A1 (en) 2019-08-21 2020-02-13 Enzyme inhibitors

Publications (3)

Publication Number Publication Date
JP2022545159A JP2022545159A (ja) 2022-10-26
JP2022545159A5 true JP2022545159A5 (https=) 2023-02-20
JPWO2021032938A5 JPWO2021032938A5 (https=) 2023-02-20

Family

ID=67777358

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022503834A Ceased JP2022545159A (ja) 2019-08-21 2020-02-13 酵素阻害剤

Country Status (15)

Country Link
US (1) US20220289727A1 (https=)
EP (1) EP4017850A1 (https=)
JP (1) JP2022545159A (https=)
KR (1) KR20220050925A (https=)
CN (1) CN114258392A (https=)
AR (1) AR118083A1 (https=)
AU (1) AU2020331720A1 (https=)
BR (1) BR112022001390A2 (https=)
CA (1) CA3148028A1 (https=)
CO (1) CO2022000270A2 (https=)
IL (1) IL289778A (https=)
MX (1) MX2022000811A (https=)
PH (1) PH12022550118A1 (https=)
TW (1) TW202115021A (https=)
WO (2) WO2021032935A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201609607D0 (en) 2016-06-01 2016-07-13 Kalvista Pharmaceuticals Ltd Polymorphs of N-(3-Fluoro-4-methoxypyridin-2-yl)methyl)-3-(methoxymethyl)-1-({4-((2-oxopy ridin-1-yl)methyl)phenyl}methyl)pyrazole-4-carboxamide and salts
GB201719881D0 (en) 2017-11-29 2018-01-10 Kalvista Pharmaceuticals Ltd Solid forms of plasma kallikrein inhibitor and salts thereof
WO2021028645A1 (en) 2019-08-09 2021-02-18 Kalvista Pharmaceuticals Limited Plasma kallikrein inhibitors
EP4017587A1 (en) * 2019-08-21 2022-06-29 Kalvista Pharmaceuticals Limited Enzyme inhibitors
CN119264065A (zh) * 2023-07-05 2025-01-07 中国科学院上海有机化学研究所 一类细胞程序性坏死抑制剂及其制备方法和用途

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL123986A (en) * 1997-04-24 2011-10-31 Organon Nv Medicinal compounds
ATE306481T1 (de) * 1999-05-12 2005-10-15 Ortho Mcneil Pharm Inc Pyrazolecarboxamide zur behandlung von fettleibigkeit und anderen erkrankungen
US7320992B2 (en) * 2003-08-25 2008-01-22 Amgen Inc. Substituted 2,3-dihydro-1h-isoindol-1-one derivatives and methods of use
NZ592039A (en) 2003-08-27 2013-03-28 Ophthotech Corp Combination therapy for the treatment of ocular neovascular disorders
GB0518237D0 (en) * 2005-09-07 2005-10-19 Angeletti P Ist Richerche Bio Therapeutic compounds
US8338437B2 (en) * 2007-02-28 2012-12-25 Methylgene Inc. Amines as small molecule inhibitors
US8658635B2 (en) * 2008-06-05 2014-02-25 Glaxosmithkline Intellectual Property Development Limited Benzpyrazol derivatives as inhibitors of PI3 kinases
EP2149552A1 (de) * 2008-07-30 2010-02-03 Bayer Schering Pharma AG 5,6 substituierte Benzamid-Derivate als Modulatoren des EP2-Rezeptors
US9290485B2 (en) * 2010-08-04 2016-03-22 Novartis Ag N-((6-amino-pyridin-3-yl)methyl)-heteroaryl-carboxamides
RU2013130019A (ru) * 2010-12-03 2015-01-10 Аллерган, Инк. Новые производные азетидина в качестве модуляторов рецептора сфингозин 1-фосфата (s1p)
CN103415301A (zh) * 2011-03-09 2013-11-27 德国杰特贝林生物制品有限公司 用于与包括与人造表面接触的医疗操作一起施用的fxii抑制剂
US8404859B2 (en) * 2011-03-16 2013-03-26 Hoffmann-La Roche Inc. Thiazole and thiophene compounds
US20120252853A1 (en) * 2011-04-01 2012-10-04 H. Lundbeck A/S Positive allosteric modulators of nicotinic acetylcholine receptor
JP2014514302A (ja) * 2011-04-13 2014-06-19 メルク・シャープ・アンド・ドーム・コーポレーション Bace阻害薬としての5−置換されたイミノチアジン類およびそれのモノおよびジオキシド、組成物およびそれらの使用
US9340500B2 (en) * 2011-04-20 2016-05-17 Shionogi & Co., Ltd. Aromatic heterocyclic derivative having TRPV4-inhibiting activity
US9938269B2 (en) * 2011-06-30 2018-04-10 Abbvie Inc. Inhibitor compounds of phosphodiesterase type 10A
BR112014013136B1 (pt) * 2011-11-30 2020-05-26 F. Hoffmann-La Roche Ag Novos derivados de dihidroisoquinolina-1-ona biciclicos
AR091022A1 (es) * 2012-05-11 2014-12-30 Abbvie Inc Inhibidores del nampt
GB201300304D0 (en) 2013-01-08 2013-02-20 Kalvista Pharmaceuticals Ltd Benzylamine derivatives
MY174018A (en) 2013-05-23 2020-03-04 Kalvista Pharmaceuticals Ltd Heterocyclic derivates
CN106257976B (zh) * 2014-03-07 2021-02-02 拜奥克里斯特制药公司 人类血浆激肽释放酶抑制剂
US10772881B2 (en) * 2017-02-27 2020-09-15 Russell Dahl Quinolines that modulate SERCA and their use for treating disease
GB201421088D0 (en) 2014-11-27 2015-01-14 Kalvista Pharmaceuticals Ltd New enzyme inhibitors
CN104592204B (zh) * 2014-12-26 2017-05-17 华润赛科药业有限责任公司 达比加群衍生物及其制备方法和用途
WO2017123518A1 (en) 2016-01-11 2017-07-20 The Rockefeller University Aminotriazole immunomodulators for treating autoimmune diseases
GB201604647D0 (en) * 2016-03-18 2016-05-04 Mission Therapeutics Ltd Novel compounds
WO2017176958A1 (en) * 2016-04-06 2017-10-12 The Regents Of The University Of Michigan Monofunctional intermediates for ligand-dependent target protein degradation
AU2017269256B2 (en) 2016-05-23 2021-02-25 The Rockefeller University Aminoacylindazole immunomodulators for treatment of autoimmune diseases
US10858319B2 (en) * 2016-10-03 2020-12-08 Iomet Pharma Ltd. Indole derivatives for use in medicine
WO2018093695A1 (en) 2016-11-18 2018-05-24 Merck Sharp & Dohme Corp. FACTOR XIIa INHIBITORS
EP3541381B1 (en) 2016-11-18 2022-12-28 Merck Sharp & Dohme LLC Inhibitors of factor xiia
JP2021504490A (ja) 2017-11-29 2021-02-15 ザ ロックフェラー ユニバーシティーThe Rockefeller University 自己免疫疾患治療用ピラノピラゾールおよびピラゾロピリジン免疫調節薬
CN112585119A (zh) * 2018-08-14 2021-03-30 Epizyme股份有限公司 经取代的吲哚及其使用方法
WO2021028645A1 (en) * 2019-08-09 2021-02-18 Kalvista Pharmaceuticals Limited Plasma kallikrein inhibitors
EP4017587A1 (en) * 2019-08-21 2022-06-29 Kalvista Pharmaceuticals Limited Enzyme inhibitors

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