JP2022545158A5 - - Google Patents
Info
- Publication number
- JP2022545158A5 JP2022545158A5 JP2022503825A JP2022503825A JP2022545158A5 JP 2022545158 A5 JP2022545158 A5 JP 2022545158A5 JP 2022503825 A JP2022503825 A JP 2022503825A JP 2022503825 A JP2022503825 A JP 2022503825A JP 2022545158 A5 JP2022545158 A5 JP 2022545158A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- independently selected
- halo
- alkoxy
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/GB2019/052359 WO2021032936A1 (en) | 2019-08-21 | 2019-08-21 | Enzyme inhibitors |
| GBPCT/GB2019/052359 | 2019-08-21 | ||
| PCT/GB2020/050332 WO2021032937A1 (en) | 2019-08-21 | 2020-02-13 | Enzyme inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022545158A JP2022545158A (ja) | 2022-10-26 |
| JP2022545158A5 true JP2022545158A5 (https=) | 2023-02-20 |
| JP7566870B2 JP7566870B2 (ja) | 2024-10-15 |
Family
ID=67777359
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022503825A Active JP7566870B2 (ja) | 2019-08-21 | 2020-02-13 | 酵素阻害剤 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20220363668A1 (https=) |
| EP (1) | EP4017587A1 (https=) |
| JP (1) | JP7566870B2 (https=) |
| KR (1) | KR20220051207A (https=) |
| CN (1) | CN114269430A (https=) |
| AR (1) | AR118085A1 (https=) |
| AU (1) | AU2020333222A1 (https=) |
| BR (1) | BR112022000936A2 (https=) |
| CA (1) | CA3147228A1 (https=) |
| CO (1) | CO2022000266A2 (https=) |
| IL (1) | IL289783A (https=) |
| MX (1) | MX2022002069A (https=) |
| PH (1) | PH12022550078A1 (https=) |
| TW (1) | TW202115033A (https=) |
| WO (2) | WO2021032936A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201609607D0 (en) | 2016-06-01 | 2016-07-13 | Kalvista Pharmaceuticals Ltd | Polymorphs of N-(3-Fluoro-4-methoxypyridin-2-yl)methyl)-3-(methoxymethyl)-1-({4-((2-oxopy ridin-1-yl)methyl)phenyl}methyl)pyrazole-4-carboxamide and salts |
| GB201719881D0 (en) | 2017-11-29 | 2018-01-10 | Kalvista Pharmaceuticals Ltd | Solid forms of plasma kallikrein inhibitor and salts thereof |
| EP4010333A1 (en) | 2019-08-09 | 2022-06-15 | Kalvista Pharmaceuticals Limited | Plasma kallikrein inhibitors |
| WO2021032935A1 (en) * | 2019-08-21 | 2021-02-25 | Kalvista Pharmaceuticals Limited | Enzyme inhibitors |
| WO2025153806A1 (en) * | 2024-01-15 | 2025-07-24 | Kalvista Pharmaceuticals Limited | Methods for determining amidolytic activity |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ592039A (en) | 2003-08-27 | 2013-03-28 | Ophthotech Corp | Combination therapy for the treatment of ocular neovascular disorders |
| US9352016B2 (en) | 2011-03-09 | 2016-05-31 | Csl Behring Gmbh | Factor XII inhibitors for the administration with medical procedures comprising contact with artificial surfaces |
| GB2517908A (en) * | 2013-08-14 | 2015-03-11 | Kalvista Pharmaceuticals Ltd | Bicyclic inhibitors |
| WO2015171527A1 (en) * | 2014-05-05 | 2015-11-12 | Global Blood Therapeutics, Inc. | Pyrazolopyridine pyrazolopyrimidine and related compounds |
| GB201421088D0 (en) | 2014-11-27 | 2015-01-14 | Kalvista Pharmaceuticals Ltd | New enzyme inhibitors |
| WO2017123518A1 (en) | 2016-01-11 | 2017-07-20 | The Rockefeller University | Aminotriazole immunomodulators for treating autoimmune diseases |
| AU2017269256B2 (en) | 2016-05-23 | 2021-02-25 | The Rockefeller University | Aminoacylindazole immunomodulators for treatment of autoimmune diseases |
| EP3541375B1 (en) | 2016-11-18 | 2023-08-23 | Merck Sharp & Dohme LLC | Factor xiia inhibitors |
| WO2018093716A1 (en) | 2016-11-18 | 2018-05-24 | Merck Sharp & Dohme Corp. | FACTOR XIIa INHIBITORS |
| EP3716972A4 (en) | 2017-11-29 | 2021-08-25 | The Rockefeller University | PYRANOPYRAZOLE AND PYRAZOLOPYRIDINE IMMUNOMODULATORS FOR THE TREATMENT OF AUTOIMMUNE DISEASES |
| WO2021032935A1 (en) * | 2019-08-21 | 2021-02-25 | Kalvista Pharmaceuticals Limited | Enzyme inhibitors |
-
2019
- 2019-08-21 WO PCT/GB2019/052359 patent/WO2021032936A1/en not_active Ceased
- 2019-08-21 CN CN201980099528.XA patent/CN114269430A/zh active Pending
- 2019-08-21 EP EP19759703.2A patent/EP4017587A1/en not_active Withdrawn
-
2020
- 2020-02-13 AR ARP200100399A patent/AR118085A1/es not_active Application Discontinuation
- 2020-02-13 MX MX2022002069A patent/MX2022002069A/es unknown
- 2020-02-13 PH PH1/2022/550078A patent/PH12022550078A1/en unknown
- 2020-02-13 CA CA3147228A patent/CA3147228A1/en active Pending
- 2020-02-13 BR BR112022000936A patent/BR112022000936A2/pt not_active Application Discontinuation
- 2020-02-13 TW TW109104437A patent/TW202115033A/zh unknown
- 2020-02-13 KR KR1020227008821A patent/KR20220051207A/ko not_active Withdrawn
- 2020-02-13 WO PCT/GB2020/050332 patent/WO2021032937A1/en not_active Ceased
- 2020-02-13 AU AU2020333222A patent/AU2020333222A1/en active Pending
- 2020-02-13 US US17/634,367 patent/US20220363668A1/en not_active Abandoned
- 2020-02-13 JP JP2022503825A patent/JP7566870B2/ja active Active
-
2022
- 2022-01-12 IL IL289783A patent/IL289783A/en unknown
- 2022-01-17 CO CONC2022/0000266A patent/CO2022000266A2/es unknown
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