JP2022543038A5 - - Google Patents

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Publication number
JP2022543038A5
JP2022543038A5 JP2022506401A JP2022506401A JP2022543038A5 JP 2022543038 A5 JP2022543038 A5 JP 2022543038A5 JP 2022506401 A JP2022506401 A JP 2022506401A JP 2022506401 A JP2022506401 A JP 2022506401A JP 2022543038 A5 JP2022543038 A5 JP 2022543038A5
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JP
Japan
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polymerosomes
group
antigen
poly
pharmaceutical product
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JP2022506401A
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English (en)
Japanese (ja)
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JP2022543038A (ja
JP7676030B2 (ja
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Priority claimed from PCT/EP2020/071809 external-priority patent/WO2021019102A2/en
Publication of JP2022543038A publication Critical patent/JP2022543038A/ja
Publication of JP2022543038A5 publication Critical patent/JP2022543038A5/ja
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Publication of JP7676030B2 publication Critical patent/JP7676030B2/ja
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JP2022506401A 2019-08-01 2020-08-03 関連づけられた抗原を有するポリマーソームの集団を、関連づけられたアジュバントを有するポリマーソームの集団と一緒に投与することによって、免疫応答を誘発する方法、およびそれら2つのポリマーソーム集団を含む組成物 Active JP7676030B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP19189549 2019-08-01
EP19189549.9 2019-08-01
EP20171327.8 2020-04-24
EP20171327 2020-04-24
PCT/EP2020/071809 WO2021019102A2 (en) 2019-08-01 2020-08-03 A method of eliciting an immune response by administering a population of polymersomes having an associated antigen together with a population of polymersomes having an associated adjuvant as well as compositions comprising the two populations of polymersomes

Publications (3)

Publication Number Publication Date
JP2022543038A JP2022543038A (ja) 2022-10-07
JP2022543038A5 true JP2022543038A5 (enExample) 2024-02-20
JP7676030B2 JP7676030B2 (ja) 2025-05-14

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ID=72148072

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022506401A Active JP7676030B2 (ja) 2019-08-01 2020-08-03 関連づけられた抗原を有するポリマーソームの集団を、関連づけられたアジュバントを有するポリマーソームの集団と一緒に投与することによって、免疫応答を誘発する方法、およびそれら2つのポリマーソーム集団を含む組成物

Country Status (9)

Country Link
US (1) US20220273792A1 (enExample)
EP (1) EP4007597A2 (enExample)
JP (1) JP7676030B2 (enExample)
CN (1) CN114502191B (enExample)
AU (1) AU2020322107A1 (enExample)
BR (1) BR112022001185A2 (enExample)
CA (1) CA3143533A1 (enExample)
PH (1) PH12022550112A1 (enExample)
WO (1) WO2021019102A2 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104936579B (zh) * 2012-11-19 2020-02-07 新加坡科技研究局 用于引发对免疫原的免疫响应的方法
US20180128545A1 (en) 2016-11-08 2018-05-10 Berry Metal Company Modular furnace cooling wall
US12384811B2 (en) 2019-04-05 2025-08-12 Academia Sinica Sialidase-resistant saccharide and method of making and using the same
KR102657261B1 (ko) * 2020-04-03 2024-04-15 조선대학교산학협력단 Covid-19 진단을 위한 재조합 코로나-19 바이러스 스파이크 단백질의 생산 및 이의 용도
WO2021214339A2 (en) * 2020-04-24 2021-10-28 Acm Biolabs Pte Ltd Vaccine against human-pathogenic coronaviruses
TWI870591B (zh) 2020-05-08 2025-01-21 中央研究院 嵌合流感疫苗
JP2023550094A (ja) * 2020-11-12 2023-11-30 ティースキャン セラピューティクス インコーポレイテッド Sars-cov-2免疫優性ペプチドの構築物及びその使用
JP2024500360A (ja) * 2020-12-11 2024-01-09 エイシーエム バイオラブズ プライベート リミテッド 関連づけられた抗原および関連づけられたアジュバントを有する2つのポリマーソーム集団を投与することによる、Th1/Th2免疫応答の調整方法
CN117597109A (zh) * 2021-02-02 2024-02-23 Acm 生物实验室私人有限公司 聚合物囊泡相关联的佐剂用于刺激免疫应答的单独使用
WO2022171182A1 (zh) * 2021-02-10 2022-08-18 斯微(上海)生物科技股份有限公司 一种治疗或者预防冠状病毒病突变株的疫苗试剂
WO2022180635A1 (en) * 2021-02-25 2022-09-01 Migvax Ltd. Oral compositions and use of same in vaccination
US20240181041A1 (en) * 2021-03-16 2024-06-06 The Wistar Institute Adenovirus SARS-CoV-2 Vaccine
US20220323569A1 (en) * 2021-03-30 2022-10-13 Qiang Chen Plant-produced vlps and ric vaccines
WO2022212505A1 (en) * 2021-03-30 2022-10-06 Arizona Board Of Regents On Behalf Of Arizona State University Optimal production of sars-cov-2 virus-like particles (vlps) produced in mammalian cells
BR112023005961A2 (pt) * 2021-04-12 2023-10-24 Academia Sinica Molécula de ácido nucleico modificada, vacina combinada, nanopartícula, nanocluster de mrna, método para prevenir ou tratar uma infecção por coronavírus, método para reforço de uma resposta imune adaptativa, peptídeo imunogênico e composição imunogênica
BR112023000666A2 (pt) * 2021-04-12 2023-10-24 Academia Sinica Imunógeno, composição imunogênica, método para induzir uma resposta imune contra um coronavírus 2 da síndrome respiratória aguda grave e uso da composição imunogênica
CN115337404A (zh) * 2021-05-12 2022-11-15 中国医学科学院基础医学研究所 细胞微颗粒在治疗呼吸道病毒性肺炎上的应用
WO2022251101A2 (en) * 2021-05-24 2022-12-01 nference, inc. Compositions and methods related to surge-associated sars-cov-2 mutants
WO2023004415A2 (en) * 2021-07-22 2023-01-26 University Of Miami Sars-cov-2 vaccine using bacterial spores expressing antigenic fragments
CN113633764B (zh) * 2021-09-02 2024-05-14 中国食品药品检定研究院 一种含佐剂的新冠dna疫苗
IT202100023816A1 (it) * 2021-09-16 2023-03-16 Takis S R L Anticorpo contro SARS-CoV-2 e suoi usi in campo medico.
TW202334429A (zh) 2021-10-01 2023-09-01 中央研究院 Sars-cov-2棘蛋白特異性抗體及其用途
WO2023060220A1 (en) * 2021-10-07 2023-04-13 BioVaxys Inc. Methods of immunization against coronavirus
CN114470186B (zh) * 2022-02-17 2023-10-20 唐颐控股(深圳)有限公司 一种可吸入式纳米新冠疫苗的制备方法
AU2024252371B2 (en) 2023-04-08 2026-02-12 Rock Biomedical Inc. Methods and compositions for dendritic cell targeting nano-delivery
US12318485B2 (en) 2023-04-08 2025-06-03 Rock Biomedical, Inc. Methods and compositions for targeted delivery by polymersomes
WO2024238734A2 (en) 2023-05-17 2024-11-21 Rock Biomedical Inc. Mgat1 deficient cells and uses thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5354934A (en) 1993-02-04 1994-10-11 Amgen Inc. Pulmonary administration of erythropoietin
JP2002514397A (ja) * 1998-05-14 2002-05-21 コーリー ファーマシューティカル ゲーエムベーハー CpGオリゴヌクレオチドを用いる造血調節の方法
US6835394B1 (en) * 1999-12-14 2004-12-28 The Trustees Of The University Of Pennsylvania Polymersomes and related encapsulating membranes
US20080181939A1 (en) * 1999-12-14 2008-07-31 Trustees Of The University Of Pennsylvania Polymersomes and related encapsulating membranes
EP2281033B1 (en) 2008-04-17 2014-10-15 Vin de Bona Trading Co Pte Post release modification of viral envelopes
US8323696B2 (en) 2008-08-29 2012-12-04 Ecole Polytechnique Federale De Lausanne Nanoparticles for immunotherapy
CN102460150B (zh) 2009-04-20 2015-05-20 新加坡科技研究局 囊泡系统及其用途
CN102917690B (zh) * 2010-03-19 2016-08-24 麻省理工学院 脂质囊泡组合物和使用方法
EP2601262A4 (en) 2010-08-05 2014-01-22 Agency Science Tech & Res VESIGN STRUCTURE WITH SEVERAL CHAMBERS AND METHOD FOR THEIR EDUCATION
EP4218808A3 (en) 2012-03-12 2023-08-09 Advanced BioAdjuvants, LLC Adjuvant and vaccine compositions
DK2906717T3 (en) 2012-10-11 2019-04-01 Vin De Bona Trading Company Pte Ltd PROCEDURE FOR PAINTING MICROVESICS
CN104936579B (zh) 2012-11-19 2020-02-07 新加坡科技研究局 用于引发对免疫原的免疫响应的方法
EP2898894A1 (en) 2014-01-27 2015-07-29 LTS LOHMANN Therapie-Systeme AG Nano-in-micro particles for intradermal delivery
WO2016055611A1 (en) * 2014-10-09 2016-04-14 Universität Basel Self-assembled nanostructures and methods of use thereof
US9636397B2 (en) 2015-03-24 2017-05-02 VaxLiant, LLC Adjuvant compositions and related methods
WO2019145475A2 (en) * 2018-01-25 2019-08-01 Acm Biolabs Pte Ltd Polymersomes comprising a soluble encapsulated antigen as well as methods of making and uses thereof
CN108969771B (zh) * 2018-08-07 2021-06-29 中国医学科学院生物医学工程研究所 甘露糖修饰的共载抗原和双免疫激动剂磷脂杂化聚合物囊泡及其制备方法与应用

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