JP2022541459A5 - - Google Patents

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Publication number
JP2022541459A5
JP2022541459A5 JP2022502422A JP2022502422A JP2022541459A5 JP 2022541459 A5 JP2022541459 A5 JP 2022541459A5 JP 2022502422 A JP2022502422 A JP 2022502422A JP 2022502422 A JP2022502422 A JP 2022502422A JP 2022541459 A5 JP2022541459 A5 JP 2022541459A5
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JP
Japan
Prior art keywords
polypeptide according
subject
conjugated polypeptide
soluble
sequence numbers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022502422A
Other languages
English (en)
Japanese (ja)
Other versions
JP7685985B2 (ja
JP2022541459A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/042161 external-priority patent/WO2021011673A2/en
Publication of JP2022541459A publication Critical patent/JP2022541459A/ja
Publication of JP2022541459A5 publication Critical patent/JP2022541459A5/ja
Application granted granted Critical
Publication of JP7685985B2 publication Critical patent/JP7685985B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2022502422A 2019-07-16 2020-07-15 アルツハイマー病の処置のための中和抗アミロイドベータ抗体 Active JP7685985B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962874724P 2019-07-16 2019-07-16
US62/874,724 2019-07-16
PCT/US2020/042161 WO2021011673A2 (en) 2019-07-16 2020-07-15 Neutralizing anti-amyloid beta antibodies for the treatment of alzheimer's disease

Publications (3)

Publication Number Publication Date
JP2022541459A JP2022541459A (ja) 2022-09-26
JP2022541459A5 true JP2022541459A5 (https=) 2023-07-24
JP7685985B2 JP7685985B2 (ja) 2025-05-30

Family

ID=71895293

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022502422A Active JP7685985B2 (ja) 2019-07-16 2020-07-15 アルツハイマー病の処置のための中和抗アミロイドベータ抗体

Country Status (7)

Country Link
US (1) US20230107034A1 (https=)
EP (1) EP3999532A2 (https=)
JP (1) JP7685985B2 (https=)
KR (1) KR20220034857A (https=)
CN (3) CN115175932B (https=)
CA (1) CA3147239A1 (https=)
WO (1) WO2021011673A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111201030B (zh) 2017-07-25 2024-11-01 真和制药有限公司 通过阻断tim-3和其配体的相互作用治疗癌症
WO2020160156A2 (en) 2019-01-30 2020-08-06 Immutics, Inc. Anti-gal3 antibodies and uses thereof
EP4157338A4 (en) 2020-05-26 2024-11-13 TrueBinding, Inc. METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING
WO2026082154A1 (en) * 2024-10-18 2026-04-23 Lepu Biopharma Co., Ltd. Anti-beta amyloid antibodies and uses thereof

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Publication number Priority date Publication date Assignee Title
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
WO1993008829A1 (en) 1991-11-04 1993-05-13 The Regents Of The University Of California Compositions that mediate killing of hiv-infected cells
EP0627932B1 (en) 1992-11-04 2002-05-08 City Of Hope Antibody construct
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
WO1996033761A1 (en) 1995-04-28 1996-10-31 Medtronic, Inc. Intraparenchymal infusion catheter system
BR9606706A (pt) 1995-10-16 1999-04-06 Unilever Nv Análogo de fragmento de anticorpo biespecífico ou bivalente uso processo para produzir o mesmo
GB9524973D0 (en) 1995-12-06 1996-02-07 Lynxvale Ltd Viral vectors
US5735814A (en) 1996-04-30 1998-04-07 Medtronic, Inc. Techniques of treating neurodegenerative disorders by brain infusion
US20030068316A1 (en) * 1997-02-05 2003-04-10 Klein William L. Anti-ADDL antibodies and uses thereof
ATE299938T1 (de) 1997-05-02 2005-08-15 Genentech Inc Ein verfahren zur herstellung multispezifischer antikörper die heteromultimere und gemeinsame komponenten besitzen
CA2410551A1 (en) 2000-06-30 2002-01-10 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw (Vib) Heterodimeric fusion proteins
EP1545582A4 (en) 2002-10-01 2008-09-17 Univ Northwestern DIFFUSIBLE DERIVATIVES DERIVED FROM AMYLOID BETA (ADDL), ADDL SUBSTITUTE, ADDL BINDING MOLECULES, AND USES THEREOF
US20160213794A1 (en) * 2002-10-01 2016-07-28 Northwestern University Amyloid beta-derived diffusible ligands (addls), addl-surrogates, addl-binding molecules and uses thereof
AU2004266159A1 (en) 2003-08-22 2005-03-03 Biogen Idec Ma Inc. Improved antibodies having altered effector function and methods for making the same
AU2006232287B2 (en) 2005-03-31 2011-10-06 Chugai Seiyaku Kabushiki Kaisha Methods for producing polypeptides by regulating polypeptide association
US7612181B2 (en) 2005-08-19 2009-11-03 Abbott Laboratories Dual variable domain immunoglobulin and uses thereof
PE20090329A1 (es) * 2007-05-30 2009-03-27 Abbott Lab Anticuerpos humanizados contra el globulomero ab(20-42) y sus usos
ES2529174T3 (es) * 2007-06-12 2015-02-17 Ac Immune S.A. Anticuerpos humanizados para amiloide beta
EP2050764A1 (en) 2007-10-15 2009-04-22 sanofi-aventis Novel polyvalent bispecific antibody format and uses thereof
JP6157046B2 (ja) 2008-01-07 2017-07-05 アムジェン インコーポレイテッド 静電的ステアリング(electrostaticsteering)効果を用いた抗体Fcヘテロ二量体分子を作製するための方法
CA2742969A1 (en) * 2008-11-07 2010-05-14 Fabrus Llc Anti-dll4 antibodies and uses thereof
EP2560681A4 (en) * 2010-04-22 2013-09-25 Janssen Alzheimer Immunotherap USE OF TAU FOR MONITORING IMMUNOTHERAPY
EP2593475B1 (en) * 2010-07-14 2016-03-02 Merck Sharp & Dohme Corp. Anti-addl monoclonal antibody and uses thereof
SMT202000340T1 (it) * 2012-10-15 2020-07-08 Medimmune Ltd Anticorpi contro il beta amiloide

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