JP2022536934A - ｉｎ ｖｉｖｏ二重リコンビナーゼ媒介カセット交換（ｄＲＭＣＥ）のためのシステム及び方法ならびにその疾患モデル - Google Patents

ｉｎ ｖｉｖｏ二重リコンビナーゼ媒介カセット交換（ｄＲＭＣＥ）のためのシステム及び方法ならびにその疾患モデル Download PDF

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JP2022536934A
JP2022536934A JP2021574914A JP2021574914A JP2022536934A JP 2022536934 A JP2022536934 A JP 2022536934A JP 2021574914 A JP2021574914 A JP 2021574914A JP 2021574914 A JP2021574914 A JP 2021574914A JP 2022536934 A JP2022536934 A JP 2022536934A
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cells
cell
transgene
recombinase
madr
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ジョシュア ブルーニグ
モイーズ ダニエルポア
ギ ブン キム
アルベルト アヤラ－サルミエント
エイミー ヤン
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シーダーズ－サイナイ メディカル センター
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    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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JP2021574914A 2019-06-17 2020-06-16 ｉｎ ｖｉｖｏ二重リコンビナーゼ媒介カセット交換（ｄＲＭＣＥ）のためのシステム及び方法ならびにその疾患モデル Pending JP2022536934A (ja)

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PCT/US2020/037946 WO2020257205A1 (en) 2019-06-17 2020-06-16 SYSTEMS AND METHODS FOR IN VIVO DUAL RECOMBINASE-MEDIATED CASSETTE EXCHANGE (dRMCE) AND DISEASE MODELS THEREOF

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WO2024071424A1 (ja) * 2022-09-29 2024-04-04 慶應義塾 細胞内の応答を引き起こす機能性分子の探索方法

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WO2017131926A1 (en) 2016-01-26 2017-08-03 Cedars-Sinai Medical Center SYSTEMS AND METHODS FOR IN VIVO DUAL RECOMBINASE-MEDIATED CASSETTE EXCHANGE (dRMCE) AND DISEASE MODELS THEREOF
WO2019178550A1 (en) 2018-03-16 2019-09-19 Cedars-Sinai Medical Center Methods and compositions for inducible expression of neurotrophic factors
CN114480457A (zh) * 2021-12-21 2022-05-13 浙江大学 一种基于pCAG-flox-neo载体的高效稳定的定点整合基因敲入方法
CN114438039A (zh) * 2022-04-07 2022-05-06 中国科学院天津工业生物技术研究所 一种哺乳动物细胞疾病模型的高通量构建方法
CN118460688A (zh) * 2023-02-09 2024-08-09 中国人民解放军军事科学院军事医学研究院 多聚甲醛固定细胞的单细胞转录组及多重靶向蛋白质同时检测方法的建立
CN116463380A (zh) * 2023-03-30 2023-07-21 中国科学院深圳先进技术研究院 一种重组腺相关病毒载体组合物、外源基因表达系统及方法
WO2024243040A2 (en) * 2023-05-19 2024-11-28 The Board Of Trustees Of The Leland Stanford Junior University High-throughput multiomic readout of rna and genomic dna within single cells
IT202300019377A1 (it) * 2023-09-20 2025-03-20 Univ Degli Studi Di Pavia Linee di cellule staminali contenenti proteine endogene marcate con espressione differenziale, metodi di produzione e loro utilizzo per l’identificazione del ciclo cellulare
CN118086394B (zh) * 2024-04-24 2024-07-12 中国农业科学院北京畜牧兽医研究所 猪脂肪组织发育示踪系统及应用

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JP2019511243A (ja) * 2016-01-26 2019-04-25 シーダーズ−サイナイ メディカル センター インビボのデュアルリコンビナーゼ媒介性カセット交換（ｄＲＭＣＥ）のためのシステム及び方法ならびにその疾患モデル

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EP1614755A1 (en) * 2004-07-07 2006-01-11 ARTEMIS Pharmaceuticals GmbH Target transgenesis of short hairpin RNA expression cassette using recombinase mediated cassette exchange
WO2011001247A2 (en) * 2009-06-29 2011-01-06 University Of Basel Methods and kits for high efficiency engineering of conditional mouse alleles
JP6856919B2 (ja) * 2016-05-10 2021-04-14 大学共同利用機関法人情報・システム研究機構 ベクターシステム、遺伝子発現方法、標的遺伝子ノックアウト方法、標的遺伝子ノックダウン方法、標的遺伝子編集方法、及び遺伝子発現キット

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JP2019511243A (ja) * 2016-01-26 2019-04-25 シーダーズ−サイナイ メディカル センター インビボのデュアルリコンビナーゼ媒介性カセット交換（ｄＲＭＣＥ）のためのシステム及び方法ならびにその疾患モデル

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024071424A1 (ja) * 2022-09-29 2024-04-04 慶應義塾 細胞内の応答を引き起こす機能性分子の探索方法

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CA3143981A1 (en) 2020-12-24
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