JP2022534420A5 - - Google Patents

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Publication number
JP2022534420A5
JP2022534420A5 JP2021570895A JP2021570895A JP2022534420A5 JP 2022534420 A5 JP2022534420 A5 JP 2022534420A5 JP 2021570895 A JP2021570895 A JP 2021570895A JP 2021570895 A JP2021570895 A JP 2021570895A JP 2022534420 A5 JP2022534420 A5 JP 2022534420A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
composition according
alkyl
hydrogen
alkenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021570895A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022534420A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/035592 external-priority patent/WO2020243720A1/en
Publication of JP2022534420A publication Critical patent/JP2022534420A/ja
Publication of JP2022534420A5 publication Critical patent/JP2022534420A5/ja
Pending legal-status Critical Current

Links

JP2021570895A 2019-05-31 2020-06-01 眼のタンパク質凝集疾患を治療するための薬剤 Pending JP2022534420A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962855560P 2019-05-31 2019-05-31
US62/855,560 2019-05-31
PCT/US2020/035592 WO2020243720A1 (en) 2019-05-31 2020-06-01 Pharmacological agents for treating protein aggregation diseases of the eye

Publications (2)

Publication Number Publication Date
JP2022534420A JP2022534420A (ja) 2022-07-29
JP2022534420A5 true JP2022534420A5 (https=) 2023-06-09

Family

ID=73553335

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021570895A Pending JP2022534420A (ja) 2019-05-31 2020-06-01 眼のタンパク質凝集疾患を治療するための薬剤

Country Status (8)

Country Link
US (1) US20220241247A1 (https=)
EP (1) EP3976017A4 (https=)
JP (1) JP2022534420A (https=)
CN (1) CN114173771A (https=)
BR (1) BR112021024151A2 (https=)
CA (1) CA3141998A1 (https=)
MX (1) MX2021014682A (https=)
WO (1) WO2020243720A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4097092A1 (en) * 2020-01-28 2022-12-07 Protego Biopharma, Inc. Compounds, compositions and methods for stabilizing transthyretin and inhibiting transthyretin misfolding
US20250019352A1 (en) * 2021-06-29 2025-01-16 Plex Pharmaceuticals, Inc. Pharmacological agents for treating ophthalmic diseases
WO2023009585A2 (en) * 2021-07-28 2023-02-02 Protego Biopharma, Inc. Transthyretin stabilizing compounds

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005113523A1 (en) * 2004-05-20 2005-12-01 Foldrx Pharmaceuticals, Inc. 2-((hetero) aryl)-benzoxazole compounds and derivatives, compositions and methods for stabilizing transthyretin and inhibiting transthyretin misfolding
WO2011116123A1 (en) * 2010-03-19 2011-09-22 Irm Llc Tafamidis for the treatment of ophthalmic diseases
RU2586330C2 (ru) * 2011-09-16 2016-06-10 Пфайзер Инк. Твердые формы ингибитора диссоциации транстиретина
RU2747536C2 (ru) * 2011-10-24 2021-05-06 Сом Инновэйшн Биотек, С.Л. Новая терапия транстиретин-ассоциированного амилоидоза
US9499527B2 (en) * 2012-05-10 2016-11-22 Cellix Bio Private Limited Compositions and methods for the treatment of familial amyloid polyneuropathy
US9169214B2 (en) * 2012-12-21 2015-10-27 The Board Of Trustees Of The Leland Stanford Junior University Compounds and compositions that bind and stabilize transthyretin and their use for inhibiting transthyretin amyloidosis and protein-protein interactions
US9790269B2 (en) * 2013-02-08 2017-10-17 Misfolding Diagnostics, Inc. Transthyretin antibodies and uses thereof
RU2015138891A (ru) * 2013-03-08 2017-04-11 Аллерган, Инк. Конъюгаты антибиотиков, напрямую связанные со стероидными препаратами
PE20151747A1 (es) * 2013-03-14 2015-12-18 Univ Massachusetts Metodo para inhibir cataratas y presbicia
US11872236B2 (en) * 2018-04-05 2024-01-16 Calasia Pharmaceuticals, Inc. Pharmacological agents for treating ocular diseases

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